Interferon- γ-induced GBP1 is an inhibitor of human papillomavirus 18
Human papillomavirus (HPV) infection is an important factor leading to cervical cell abnormalities. 90% of cervical cancers are closely associated with persistent infection of high-risk HPV, with the highest c... (Source: BMC Women's Health)
Source: BMC Women's Health - April 15, 2024 Category: OBGYN Authors: Min Xu, Miao-Chun Lin and Zhao-Hui Li Tags: Research Source Type: research

Pattern of multiple human papillomavirus infection and type competition: An analysis in healthy Chinese women aged 18 –45 years
Volume 20, Issue 1, December 2024 . (Source: Human Vaccines and Immunotherapeutics)
Source: Human Vaccines and Immunotherapeutics - April 15, 2024 Category: Allergy & Immunology Authors: Yingying SuTingquan ZhengZhaofeng BiXinhua JiaYufei LiXuefeng KuangYuan YangQi ChenHongyan LinYue HuangShoujie HuangYoulin QiaoTing WuJun ZhangNingshao Xiaa State Key Laboratory of Vaccines for Infectious Diseases, Xiang an Biomedicine Laboratory, School Source Type: research

Predictable changes in the accuracy of human papillomavirus tests after vaccination: review with implications for performance monitoring in cervical screening
British Journal of Cancer, Published online: 13 April 2024; doi:10.1038/s41416-024-02681-zPredictable changes in the accuracy of human papillomavirus tests after vaccination: review with implications for performance monitoring in cervical screening (Source: British Journal of Cancer)
Source: British Journal of Cancer - April 13, 2024 Category: Cancer & Oncology Authors: Matejka Rebolj Adam R. Brentnall Kate Cuschieri Source Type: research

Cancers, Vol. 16, Pages 1484: Plasma IL-1 and IL-6 Family Cytokines with Soluble Receptor Levels at Diagnosis in Head and Neck Squamous Cell Carcinoma: High Levels Predict Decreased Five-Year Disease-Specific and Overall Survival
In conclusion, high plasma levels of IL-6, IL-31, and IL-1RA, as well as the soluble receptors IL-6Rα, gp130, and IL33Rα, predicted clinical outcome. This shows their potential as candidates for both general therapy and immune therapy stratification, as well as being future platforms for the development of new immunotherapy. (Source: Cancers)
Source: Cancers - April 12, 2024 Category: Cancer & Oncology Authors: Helene Hersvik Aarstad Svein Erik Emblem Moe Stein Lybak Øystein Bruserud Tor Henrik Anderson Tvedt Hans J ørgen Aarstad Tags: Article Source Type: research

Pathology of Squamous Cell Carcinoma of the Penis: Back to Square One
The landscape of squamous cell carcinoma of the penis (SCC-P) has undergone a significant transformation since the new World Health Organization classification of genitourinary cancers and recent European Association of Urology/American Association of Clinical Oncology guidelines. These changes emphasize the necessity to categorize SCC-P into 2 groups based on its association with human papillomavirus (HPV) infection. This shift has major implications, considering that prior knowledge was derived from a mix of both groups. Given the distinct prognosis, treatment options, and staging systems observed for HPV-associated tumo...
Source: Urologic Clinics of North America - April 12, 2024 Category: Urology & Nephrology Authors: Diego F. Sanchez, Pedro Oliveira Source Type: research

Correction to: Impact of Different Cofactors on Naturally Acquired Human Papillomavirus Antibody Levels Among Unvaccinated Pregnant Women, by Kirjavainen, et al. Viral Immunology 2024;37(1):36 –43; doi: 10.1089/vim.2023.0108.
Viral Immunology,Volume 37, Issue 3, Page 176-176, April 2024. (Source: Viral Immunology)
Source: Viral Immunology - April 12, 2024 Category: Allergy & Immunology Source Type: research

Neoadjuvant Chemotherapy and Transoral Robotic Surgery for Oropharynx Cancer and Quality of Life
To the Editor To deintensify treatment (avoid overtreatment) for patients with human papillomavirus virus –associated oropharyngeal squamous cell carcinoma (HPV-OPSCC) is certainly one of the hot topics in head and neck cancer, driven by the goal of enhancing quality of life. Although various strategies are under exploration, the unconventional inclusion of neoadjuvant chemotherapy by Silver et al has captured our attention. (Source: JAMA Otolaryngology - Head and Neck Surgery)
Source: JAMA Otolaryngology - Head and Neck Surgery - April 11, 2024 Category: ENT & OMF Source Type: research

Neoadjuvant Chemotherapy and Transoral Robotic Surgery for Oropharynx Cancer and Quality of Life —Reply
In Reply In reaction to our recent report on quality-of-life outcomes following neoadjuvant chemotherapy and transoral robotic surgery (NECTORS) for human papillomavirus virus –associated oropharyngeal squamous cell carcinoma (HPV-OPSCC), Granell and Gutierrez-Fonseca have raised concerns to which we would like to respond. (Source: JAMA Otolaryngology - Head and Neck Surgery)
Source: JAMA Otolaryngology - Head and Neck Surgery - April 11, 2024 Category: ENT & OMF Source Type: research

Impact of high-performance HPV testing to improve cervical cancer screening in China: A prospective population-based multicenter cohort study
CONCLUSIONS: The study has indicated that HBRT-14 has a reliable clinical performance for use in cervical screening. The validated HPV test would improve the quality of population screening.PMID:38599463 | DOI:10.1016/j.cmi.2024.03.035 (Source: Cancer Control)
Source: Cancer Control - April 10, 2024 Category: Cancer & Oncology Authors: Jian Yin Shaokai Zhang Zhifang Li Yufei Li Hong Wang Xun Zhang Qinjing Pan Wen Chen Xiping Luo Xibin Sun Fanghui Zhao Youlin Qiao Source Type: research

Moving the Needle: A Qualitative Exploration of the School Nurses' Experience with Virginia's Human Papillomavirus Mandate
This study aims to understand Virginia school nurses' practice in implementing the HPV vaccine mandate through the exploration of their subjective experiences. Semi-structured interviews were conducted. Thematic analysis using the socioecological model guided data analysis. Factors that influence nursing practice were identified at all socioecological model levels The data from this study is intended to provide an understanding of school nursing practice so that interventions to improve HPV vaccination rates can be developed.PMID:38594950 | DOI:10.1177/10598405241241229 (Source: The Journal of School Nursing)
Source: The Journal of School Nursing - April 10, 2024 Category: Nursing Authors: Kimberly McNally Ali Weinstein Lisa Lindley Robin Wallin Amira Roess Source Type: research

Biplex quantitative PCR to detect transcriptionally active human papillomavirus 16 from patient saliva
Head and neck cancers, particularly oropharyngeal cancers (OPC), have been increasingly associated with human papillomavirus (HPV) infections, specifically HPV16. The current methods for HPV16 detection primar... (Source: BMC Cancer)
Source: BMC Cancer - April 10, 2024 Category: Cancer & Oncology Authors: Fiona Deutsch, Dayna Sais, Ni Keatinge, Meredith Hill, Ngoc Ha Tran, Michael Elliott and Nham Tran Tags: Research Source Type: research

Cutaneous Warts Treated with Individualised Homoeopathic Medicine: A Case Series
Homœopathic Links 2024; 37: 082-093 DOI: 10.1055/s-0043-1778681Cutaneous warts are visible growths on the skin caused by infection of keratinocytes caused by the human papilloma virus. They appear in various forms on different locations on the skin and mucous membranes, the most common being hands, feet, face and neck. Despite the availability of various treatments, its persistent and recurring nature remains a matter of frustration among the medical fraternity. This case series includes eight cutaneous warts cases treated with an individualistic approach. Each case was prescribed a single medicine as per the cardinal pri...
Source: Homoeopathic Links - April 10, 2024 Category: Complementary Medicine Authors: Ram, Hanuman Singh, Uttam Tuteja, Sonia Singh, Anuradha Singh, Shweta Tags: Case Report Source Type: research

Advances and residual knowledge gaps in the neck management of head and neck squamous cell carcinoma patients with advanced nodal disease undergoing definitive (chemo)radiotherapy for their primary
ConclusionPersonalized neck management is an increasingly important aspect of the overall therapeutic strategies in cN+ HNSCC.Graphic abstract (Source: Strahlentherapie und Onkologie)
Source: Strahlentherapie und Onkologie - April 10, 2024 Category: Cancer & Oncology Source Type: research

Randomized Phase II Trial of Imiquimod with or without 9-Valent HPV Vaccine versus Observation in Patients with High-grade Pre-neoplastic Cervical Lesions (NCT02864147)
CONCLUSIONS: Although imiquimod induced a higher regression to CIN1 or less and significant increases in CD4/CD8 T cells infiltrating the cervix, it did not meet its prespecified statistical outcome for efficacy. A higher regression rate than expected was observed in the surveillance arm of this prospective trial. Future clinical trials with imiquimod targeting CIN3 patients are warranted.PMID:38592381 | DOI:10.1158/1078-0432.CCR-23-3639 (Source: Clinical Cancer Research)
Source: Clinical Cancer Research - April 9, 2024 Category: Cancer & Oncology Authors: Sangini S Sheth Ji Eun Oh Stefania Bellone Eric R Siegel Michelle Greenman Levent Mutlu Blair McNamara Shefali Pathy Mitchell Clark Masoud Azodi Gary Altwerger Vaagn Andikyan Gloria Huang Elena Ratner Daniel J Kim Akiko Iwasaki Angelique W Levi Natalia Bu Source Type: research