Maternal prepregnancy weight as an independent risk factor for congenital heart defects: systematic review and meta-analysis stratified by cardiac defect subtypes and severity
CONCLUSIONS: Maternal weight emerged as a crucial modifiable risk factor for preventing CHDs, particularly the severe forms. Future research is needed to investigate whether weight management prior to pregnancy might serve as a preventive measure against CHDs. Additionally, for pregnant women with obesity, fetal echocardiography ought to be a routine diagnostic procedure. This article is protected by copyright. All rights reserved.PMID:38629488 | DOI:10.1002/uog.27659 (Source: The Ultrasound Review of Obstetrics and Gynecology)
Source: The Ultrasound Review of Obstetrics and Gynecology - April 17, 2024 Category: Radiology Authors: N Salmeri A Seidenari P I Cavoretto M Papale M Candiani A Farina Source Type: research

Maternal prepregnancy weight as an independent risk factor for congenital heart defects: systematic review and meta-analysis stratified by cardiac defect subtypes and severity
CONCLUSIONS: Maternal weight emerged as a crucial modifiable risk factor for preventing CHDs, particularly the severe forms. Future research is needed to investigate whether weight management prior to pregnancy might serve as a preventive measure against CHDs. Additionally, for pregnant women with obesity, fetal echocardiography ought to be a routine diagnostic procedure. This article is protected by copyright. All rights reserved.PMID:38629488 | DOI:10.1002/uog.27659 (Source: The Ultrasound Review of Obstetrics and Gynecology)
Source: The Ultrasound Review of Obstetrics and Gynecology - April 17, 2024 Category: Radiology Authors: N Salmeri A Seidenari P I Cavoretto M Papale M Candiani A Farina Source Type: research

Repair of a fistula between the aorta and right ventricular outflow tract secondary to infective endocarditis of a unicuspid aortic valve and previously repaired ventricular septal defect
Infective endocarditis of the aortic valve can result in a wide range of destructive pathology beyond the valve leaflets and annulus which require careful surgical planning to provide appropriate debridement a... (Source: Journal of Cardiothoracic Surgery)
Source: Journal of Cardiothoracic Surgery - April 16, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Rickesh B. Karsan, Katie E. O ’Sullivan, Christopher J. Lockhart and Christopher Austin Tags: Case Report Source Type: research

Early and Late Results after Surgical Mitral Valve Repair: A High-Volume Center Experience
Conclusion MV surgery, both minimally invasive and via sternotomy, is associated with high repair rates, excellent perioperative outcomes, and long-term survival. Data underscore the effectiveness of surgical repair in managing MR, even in the era of advancing interventional techniques. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: The Thoracic and Cardiovascular Surgeon)
Source: The Thoracic and Cardiovascular Surgeon - April 16, 2024 Category: Cardiovascular & Thoracic Surgery Authors: G ötte, Julia Zittermann, Armin Deutsch, Marcus-Andre Schramm, Rene Bleiziffer, Sabine Renner, Andre Gummert, Jan F. Tags: Original Cardiovascular Source Type: research

Exposure to Endocrine-Disrupting Chemicals and Congenital Heart Diseases: The Pooled Results Based on the Current Evidence
In conclusion, based on the latest evidence, maternal EDC exposure may increase CHD risks in human offspring, especially in heavy metal exposure conditions. (Source: Pediatric Cardiology)
Source: Pediatric Cardiology - April 11, 2024 Category: Cardiology Source Type: research

Bartonella quintana pulmonary native valve endocarditis
AbstractBartonella quintana is a well-known cause of blood culture-negative endocarditis; however, pulmonary valve involvement is rare. The case of a 40-year-old African male who presented to the Emergency Department with chest pain, cardiac failure, and a 2-week history of fever is presented. Transoesophageal echocardiography confirmed an atrial septal defect, severe pulmonary insufficiency with large vegetations, severe mitral regurgitation due to anterior leaflet prolapse, and right ventricular dysfunction. Empirical antibiotic therapy was started, and urgent surgical intervention was decided. There were vegetations on ...
Source: Indian Journal of Thoracic and Cardiovascular Surgery - April 10, 2024 Category: Cardiovascular & Thoracic Surgery Source Type: research

Spectrum of Genital and Extragenital Anomalies in Malformation Syndromes Associated With 46, XY Disorders of Sex Development: A Single Center Experience
CONCLUSIONS: Integration between clinical, laboratory and genetic data is the cornerstone in the management of XY DSD patients for appropriate decision making of surgical intervention and sex assignment, in addition to screening for other associated features of each mutation.PMID:38584411 (Source: Indian Pediatrics)
Source: Indian Pediatrics - April 8, 2024 Category: Pediatrics Authors: Shaymaa Raafat Yasmine Abdelmeguid Mostafa Kotb Ahmed Oshiba Source Type: research

Spectrum of Genital and Extragenital Anomalies in Malformation Syndromes Associated With 46, XY Disorders of Sex Development: A Single Center Experience
CONCLUSIONS: Integration between clinical, laboratory and genetic data is the cornerstone in the management of XY DSD patients for appropriate decision making of surgical intervention and sex assignment, in addition to screening for other associated features of each mutation.PMID:38584411 (Source: Indian Pediatrics)
Source: Indian Pediatrics - April 8, 2024 Category: Pediatrics Authors: Shaymaa Raafat Yasmine Abdelmeguid Mostafa Kotb Ahmed Oshiba Source Type: research

Spectrum of Genital and Extragenital Anomalies in Malformation Syndromes Associated With 46, XY Disorders of Sex Development: A Single Center Experience
CONCLUSIONS: Integration between clinical, laboratory and genetic data is the cornerstone in the management of XY DSD patients for appropriate decision making of surgical intervention and sex assignment, in addition to screening for other associated features of each mutation.PMID:38584411 (Source: Indian Pediatrics)
Source: Indian Pediatrics - April 8, 2024 Category: Pediatrics Authors: Shaymaa Raafat Yasmine Abdelmeguid Mostafa Kotb Ahmed Oshiba Source Type: research

Early Post-operative ECG Changes as a Predictor of Post-pericardiotomy Syndrome Following Atrial Septal Defect Repair
AbstractTo identify risk factors associated with post-pericardiotomy syndrome (PPS) in patients undergoing surgical repair of atrial septal defects (ASD). A single-center retrospective study. Tertiary academic hospital. Included were patients of all ages who underwent surgical ASD repair, while exclusion criteria included the absence of post-operative electrocardiogram (ECG), lack of follow-up post-discharge and factors hindering ECG interpretation. Demographic and clinical data, including ECG changes indicative of pericardial inflammation, were collected. The primary outcome measure was the development of PPS, determined ...
Source: Mammalian Genome - April 6, 2024 Category: Genetics & Stem Cells Source Type: research

Partial heart transplantation for destructive infective endocarditis
AbstractInfective endocarditis frequently spreads beyond the valve tissue, especially in the aortic location. Invasive endocarditis may lead to abscess formation or fistula, with substantial tissue loss. Here, the case of a 31-year-old male patient with destructive aortic and pulmonary valve endocarditis and a subaortic mural defect who underwent patch closure of the ventricular septal defect and aortic and pulmonary root replacement and right coronary artery bypass graft is presented. This is an uncommon condition and stress is placed on imaging of the technical aspects of the case. (Source: Indian Journal of Thoracic and...
Source: Indian Journal of Thoracic and Cardiovascular Surgery - April 6, 2024 Category: Cardiovascular & Thoracic Surgery Source Type: research

Hypogammaglobulinemia in Two Children with Zhu-Tokita-Takenouchi-Kim Syndrome
Zhu-Tokita-Takenouchi-Kim (ZTTK) syndrome is a rare genetic disorder caused by mutations in the SON gene (a gene located on the 21q22 chromosome), associated with multisystem involvement including brain abnormalities (commonly hypoplasia or agenesis of corpus callosum and ventricular enlargement), cardiac and renal anomalies (such as atrial septal defects and vesicoureteral reflux), optic atrophy, craniofacial dysmorphism, musculoskeletal abnormalities (such as clinodactyly or syndactyly), and developmental delay/intellectual disability. (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - April 6, 2024 Category: Allergy & Immunology Authors: Payge Van Stechelman, Bridget Wilson, Theresa A. Grebe, Syed Jaffery, Cindy S. Bauer Tags: Letters Source Type: research

Hypogammaglobulinemia in 2 children with Zhu-Tokita-Takenouchi-Kim syndrome
Zhu-Tokita-Takenouchi-Kim (ZTTK) syndrome is a rare genetic disorder caused by mutations in the SON gene (a gene located on the 21q22 chromosome), associated with multisystem involvement including brain abnormalities (typically hypoplasia or agenesis of corpus callosum and ventricular enlargement), cardiac and renal anomalies (such as atrial septal defects and vesicoureteral reflux), optic atrophy, craniofacial dysmorphism, musculoskeletal abnormalities (such as clinodactyly or syndactyly), and developmental delay/intellectual disability. (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - April 6, 2024 Category: Allergy & Immunology Authors: Payge Van Stechelman, Bridget Wilson, Theresa A. Grebe, Syed Jaffery, Cindy S. Bauer Tags: Letters Source Type: research

Commentary on the mitral regurgitation outcomes after transcatheter atrial septal defect closure
In this study, they aimed to elucidate mitral regurgitation (MR) outcomes and predictors of worsening MR after transcatheter atrial septal defect (ASD) closure. Based on the univariable and multiple logistic regression analysis, they found the associations between clinical or echocardiographic findings and worsening MR, and concluded that worsening MR after transcatheter ASD closure might depend on mitral valve (MV) leaflet findings and annulus size in patients with long-standing persistent atrial fibrillation. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - April 5, 2024 Category: Cardiology Authors: Yun Cheng, Qinggang Zhang Source Type: research

Association study of FLT4 and HYDIN single nucleotide polymorphisms with atrial septal defect susceptibility in the Han Chinese population of Southwest China
This study aimed to evaluate the corre... (Source: Italian Journal of Pediatrics)
Source: Italian Journal of Pediatrics - April 5, 2024 Category: Pediatrics Authors: Ye Jin, Miao Zhao, Qiuzhe Guo, Wanyu Zhao, Min Lei, Yifei Zhang, Yunhan zhang, Yan Shen, Keqin Lin, Zhaoqing Yang, Jiayou Chu, Hao Sun and Zhiling Luo Tags: Research Source Type: research