An observational study of symmetrical VSD occluder for transcatheter closure of ruptured sinus of Valsalva aneurysm
In conclusion, the TCC of RSVA with the China made symmetrical VSD occluder is safe and effective.PMID:38655039 | PMC:PMC11036356 | DOI:10.3892/etm.2024.12532 (Source: Experimental and Therapeutic Medicine)
Source: Experimental and Therapeutic Medicine - April 24, 2024 Category: General Medicine Authors: Wei Chen Tongbin Li Xiaolin Lei Haitao Liu Source Type: research

Contribution of VEGF-B-Induced Endocardial Endothelial Cell Lineage in Physiological Versus Pathological Cardiac Hypertrophy
CONCLUSIONS: Paracrine and autocrine secretions of VEGF-B induce expansion of a specific endocardium-derived endothelial cell population with distinct angiogenic markers. However, autocrine VEGF-B signaling fails to promote VEGF-B-induced endothelial cell migration and contribution to myocardial capillaries, predisposing to septal defects and inducing a mismatch between angiogenesis and myocardial growth, which results in pathological cardiac hypertrophy.PMID:38655691 | DOI:10.1161/CIRCRESAHA.123.324136 (Source: Cell Research)
Source: Cell Research - April 24, 2024 Category: Cytology Authors: Ibrahim Sultan Markus Ramste Pim Peletier Karthik Amudhala Hemanthakumar Deepak Ramanujam Annakaisa Tirronen Ylva von Wright Salli Antila Pipsa Saharinen Lauri Eklund Eero Mervaala Seppo Yl ä-Herttuala Stefan Engelhardt Riikka Kivel ä Kari Alitalo Source Type: research

Delayed Diagnosis of Right Heart Failure Due to Sinus Venosus Atrial Septal Defect, Persistent Left Superior Vena Cava and Partial Anomalous Pulmonary Venous Return
Atrial septal defects (ASD) are an uncommon cause of right heart failure and pulmonary hypertension. Sinus venosus ASD (SVASD) are an uncommon form of ASD, amounting to 5 –10% of all ASD. They are commonly underdiagnosed as the defects are often located superior and adjacent to the superior vena cava (SVC), w... Delayed Diagnosis of Right Heart Failure Due to Sinus Venosus Atrial Septal Defect, Persistent Left Superior Vena Cava and Partial Anomalous Pulmonary Venous Return Atrial septal defects (ASD) are an uncommon cause of right heart failure and pulmonary hypertension. Sinus venosus ASD ...
Source: Radcliffe Cardiology - April 23, 2024 Category: Cardiology Authors: dbarot525787 Source Type: research

Echogenic intracardiac foci detection and location in the second-trimester ultrasound and association with fetal outcomes: A systematic literature review
ConclusionEIF alone was not associated with adverse outcomes for the infant. Only persistent EIF on the right side showed evidence of carrying a higher risk of cardiac abnormality and would warrant further follow-up. (Source: PLoS One)
Source: PLoS One - April 22, 2024 Category: Biomedical Science Authors: Hope Eleri Jones Source Type: research

Role of maternal hyperoxygenation testing to predict need for balloon atrial septostomy in fetal d-transposition of great arteries
CONCLUSIONS: In d-TGA, measurement of PFO size and direction of PDA shunting during MH testing improves our ability to predict need for BAS postnatally, although additional study is needed. We propose incorporating third trimester MH testing when planning deliveries of d-TGA fetuses. This article is protected by copyright. All rights reserved.PMID:38642340 | DOI:10.1002/uog.27664 (Source: The Ultrasound Review of Obstetrics and Gynecology)
Source: The Ultrasound Review of Obstetrics and Gynecology - April 20, 2024 Category: Radiology Authors: A Szwast C Penney P Sharma J Rychik Source Type: research

Prenatal diagnosis and outcomes for fetuses with suspected pelvic kidney
CONCLUSION: Pelvic kidney can be diagnosed in fetal abnormality screening ultrasound and postnatal follow-up should be performed closely for the assessment of renal functions.PMID:38636123 | DOI:10.1016/j.ejogrb.2024.04.014 (Source: Reproductive Biology)
Source: Reproductive Biology - April 18, 2024 Category: Reproduction Medicine Authors: Refaettin Sahin Atakan Tanacan Hakki Serbetci Osman Onur Ozkavak Murat Haksever Alperen Simsek Ozgur Kara Dilek Sahin Source Type: research

Clinical characteristics, imaging findings, management, and outcomes of patients with scimitar syndrome at a tertiary referral healthcare center in Colombia
AbstractScimitar Syndrome is part of a complex spectrum of congenital cardiovascular anomalies related to anomalous pulmonary venous return. Depending on the extent of involvement, treatment can be either expectant or surgical. Prognosis and survival have been controversial, with some results supporting early surgical management. This research aims to disclose the outcomes and describe the management, clinical and imaging characteristics of patients diagnosed with Scimitar Syndrome treated in a tertiary referral healthcare center. Longitudinal descriptive observational study. The study included all patients diagnosed with ...
Source: The International Journal of Cardiovascular Imaging - April 18, 2024 Category: Radiology Source Type: research

How do Age at the Surgery and Birth Weight Influence Post-Operative Anthropometric Parameters in Infants with Surgical Closure of Large Ventricular Septal Defects? A Prospective Cohort Study from a Lower-Middle-Income Country
AbstractClosure of the large ventricular septal defects (VSD) in infancy can lead to normalization of growth, but data are limited. Our study is done to assess the growth pattern in different age groups of children and lower birth weight babies after shunt closure. This is a prospective observational study that included infants with isolated large VSD operated in infancy. Anthropometric data were collected at baseline and at follow-up, and growth patterns were analyzed. 99 infants were included in the study. The mean age and weight at the time of surgery were 6.97  ± 2.79 months and 5.07 ± 1.16 kg, respectively...
Source: Mammalian Genome - April 18, 2024 Category: Genetics & Stem Cells Source Type: research

Maternal prepregnancy weight as an independent risk factor for congenital heart defects: systematic review and meta-analysis stratified by cardiac defect subtypes and severity
CONCLUSIONS: Maternal weight emerged as a crucial modifiable risk factor for preventing CHDs, particularly the severe forms. Future research is needed to investigate whether weight management prior to pregnancy might serve as a preventive measure against CHDs. Additionally, for pregnant women with obesity, fetal echocardiography ought to be a routine diagnostic procedure. This article is protected by copyright. All rights reserved.PMID:38629488 | DOI:10.1002/uog.27659 (Source: The Ultrasound Review of Obstetrics and Gynecology)
Source: The Ultrasound Review of Obstetrics and Gynecology - April 17, 2024 Category: Radiology Authors: N Salmeri A Seidenari P I Cavoretto M Papale M Candiani A Farina Source Type: research

Maternal prepregnancy weight as an independent risk factor for congenital heart defects: systematic review and meta-analysis stratified by cardiac defect subtypes and severity
CONCLUSIONS: Maternal weight emerged as a crucial modifiable risk factor for preventing CHDs, particularly the severe forms. Future research is needed to investigate whether weight management prior to pregnancy might serve as a preventive measure against CHDs. Additionally, for pregnant women with obesity, fetal echocardiography ought to be a routine diagnostic procedure. This article is protected by copyright. All rights reserved.PMID:38629488 | DOI:10.1002/uog.27659 (Source: The Ultrasound Review of Obstetrics and Gynecology)
Source: The Ultrasound Review of Obstetrics and Gynecology - April 17, 2024 Category: Radiology Authors: N Salmeri A Seidenari P I Cavoretto M Papale M Candiani A Farina Source Type: research

Repair of a fistula between the aorta and right ventricular outflow tract secondary to infective endocarditis of a unicuspid aortic valve and previously repaired ventricular septal defect
Infective endocarditis of the aortic valve can result in a wide range of destructive pathology beyond the valve leaflets and annulus which require careful surgical planning to provide appropriate debridement a... (Source: Journal of Cardiothoracic Surgery)
Source: Journal of Cardiothoracic Surgery - April 16, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Rickesh B. Karsan, Katie E. O ’Sullivan, Christopher J. Lockhart and Christopher Austin Tags: Case Report Source Type: research

Early and Late Results after Surgical Mitral Valve Repair: A High-Volume Center Experience
Conclusion MV surgery, both minimally invasive and via sternotomy, is associated with high repair rates, excellent perioperative outcomes, and long-term survival. Data underscore the effectiveness of surgical repair in managing MR, even in the era of advancing interventional techniques. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: The Thoracic and Cardiovascular Surgeon)
Source: The Thoracic and Cardiovascular Surgeon - April 16, 2024 Category: Cardiovascular & Thoracic Surgery Authors: G ötte, Julia Zittermann, Armin Deutsch, Marcus-Andre Schramm, Rene Bleiziffer, Sabine Renner, Andre Gummert, Jan F. Tags: Original Cardiovascular Source Type: research

Exposure to Endocrine-Disrupting Chemicals and Congenital Heart Diseases: The Pooled Results Based on the Current Evidence
In conclusion, based on the latest evidence, maternal EDC exposure may increase CHD risks in human offspring, especially in heavy metal exposure conditions. (Source: Pediatric Cardiology)
Source: Pediatric Cardiology - April 11, 2024 Category: Cardiology Source Type: research

Bartonella quintana pulmonary native valve endocarditis
AbstractBartonella quintana is a well-known cause of blood culture-negative endocarditis; however, pulmonary valve involvement is rare. The case of a 40-year-old African male who presented to the Emergency Department with chest pain, cardiac failure, and a 2-week history of fever is presented. Transoesophageal echocardiography confirmed an atrial septal defect, severe pulmonary insufficiency with large vegetations, severe mitral regurgitation due to anterior leaflet prolapse, and right ventricular dysfunction. Empirical antibiotic therapy was started, and urgent surgical intervention was decided. There were vegetations on ...
Source: Indian Journal of Thoracic and Cardiovascular Surgery - April 10, 2024 Category: Cardiovascular & Thoracic Surgery Source Type: research

Spectrum of Genital and Extragenital Anomalies in Malformation Syndromes Associated With 46, XY Disorders of Sex Development: A Single Center Experience
CONCLUSIONS: Integration between clinical, laboratory and genetic data is the cornerstone in the management of XY DSD patients for appropriate decision making of surgical intervention and sex assignment, in addition to screening for other associated features of each mutation.PMID:38584411 (Source: Indian Pediatrics)
Source: Indian Pediatrics - April 8, 2024 Category: Pediatrics Authors: Shaymaa Raafat Yasmine Abdelmeguid Mostafa Kotb Ahmed Oshiba Source Type: research