Undercooked Wheat Allergy and New Wheat Allergens - A Case Report
Wheat is an important food source worldwide, but its consumption occurs after being submitted to thermal processing.1,2 Most IgE mediated allergic reactions to wheat include food allergy, wheat-dependent exercise-induced anaphylaxis,3 respiratory allergy and contact urticaria. With the exception of baker ´s asthma, most are correlated with both unprocessed and processed wheat allergy. Only a few cases of specific unprocessed wheat food allergy have been reported3 and the allergens involved in these specific phenotypes are mostly unknown. (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - March 11, 2024 Category: Allergy & Immunology Authors: Ana Lu ísa Pinhal, Borja Bartolomé, Diana Silva Tags: Letters Source Type: research

Who are the potential patients for Omalizumab for Food Allergy?
Food allergies affect an estimated 8% of the United States population and have risen significantly in the last 20 years.1 IgE-mediated reactions to food can range from simple urticaria to life-threatening anaphylaxis. The only treatment was avoidance of the allergen and treatment of allergic reactions with epinephrine until 2020, when an oral immunotherapy (OIT) product (Palforzia) was approved for the treatment of peanut allergy.2 There was no FDA approved treatment for other foods or multiple foods until the recent approval of omalizumab for any food allergy for patients 1 years of age or older with the appropriate total...
Source: Annals of Allergy, Asthma and Immunology - March 11, 2024 Category: Allergy & Immunology Authors: Hugh A. Sampson, J. Andrew Bird, David Fleischer, Wayne G. Shreffler, Jonathan Spergel Tags: Perspective Source Type: research

Undercooked wheat allergy and new wheat allergens
Wheat is an important food source worldwide but its consumption occurs after being submitted to thermal processing.1,2 Most IgE –mediated allergic reactions to wheat include food allergy, wheat-dependent exercise-induced anaphylaxis,3 respiratory allergy, and contact urticaria. With the exception of baker´s asthma, most are correlated with both unprocessed and processed wheat allergy. Only a few cases of specific unproces sed wheat food allergy have been reported,3 and the allergens involved in these specific phenotypes are mostly unknown. (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - March 11, 2024 Category: Allergy & Immunology Authors: Ana Lu ísa Pinhal, Borja Bartolomé, Diana Silva Tags: Letters Source Type: research

Cold-induced anaphylaxis triggered by drinking cold water
We report the case of an 11-year-old boy previously diagnosed with chronic spontaneous urticaria who developed facial swelling, itchy hives, difficulty in breathing, vomiting and abdominal pain within 5 minutes of drinking cold water. He received a standard dose of non-sedating second-generation antihistamines at home. He was observed in the emergency room for 2 hours and discharged with an epinephrin autoinjector. During the subsequent outpatient clinic visit, an ice cube test was performed which confirmed the new diagnosis of comorbid cold-induced chronic urticaria. On further questioning, the parents reported occurrence...
Source: Allergologia et Immunopathologia - March 9, 2024 Category: Allergy & Immunology Authors: Abdulaziz S Alrafiaah Elena Netchiporouk Moshe Ben-Shoshan Source Type: research

Safety of direct oral provocation test to delabel reported mild beta-lactam allergy in infants
CONCLUSIONS: A direct DPT without prior tests is a safe and effective procedure to delabel BL allergy, even in infants. The authors wish to emphasize the importance of properly validating BL allergy suspicions by promoting appropriate diagnostic procedures in infants as, in most cases, DHRs can be excluded and there is no need for further therapeutic restrictions.PMID:38459885 | DOI:10.15586/aei.v52i2.887 (Source: Allergologia et Immunopathologia)
Source: Allergologia et Immunopathologia - March 9, 2024 Category: Allergy & Immunology Authors: Francisca Cunha In ês Cunha Eva Gomes Source Type: research

Cold-induced anaphylaxis triggered by drinking cold water
We report the case of an 11-year-old boy previously diagnosed with chronic spontaneous urticaria who developed facial swelling, itchy hives, difficulty in breathing, vomiting and abdominal pain within 5 minutes of drinking cold water. He received a standard dose of non-sedating second-generation antihistamines at home. He was observed in the emergency room for 2 hours and discharged with an epinephrin autoinjector. During the subsequent outpatient clinic visit, an ice cube test was performed which confirmed the new diagnosis of comorbid cold-induced chronic urticaria. On further questioning, the parents reported occurrence...
Source: Allergologia et Immunopathologia - March 9, 2024 Category: Allergy & Immunology Authors: Abdulaziz S Alrafiaah Elena Netchiporouk Moshe Ben-Shoshan Source Type: research

Safety of direct oral provocation test to delabel reported mild beta-lactam allergy in infants
CONCLUSIONS: A direct DPT without prior tests is a safe and effective procedure to delabel BL allergy, even in infants. The authors wish to emphasize the importance of properly validating BL allergy suspicions by promoting appropriate diagnostic procedures in infants as, in most cases, DHRs can be excluded and there is no need for further therapeutic restrictions.PMID:38459885 | DOI:10.15586/aei.v52i2.887 (Source: Allergologia et Immunopathologia)
Source: Allergologia et Immunopathologia - March 9, 2024 Category: Allergy & Immunology Authors: Francisca Cunha In ês Cunha Eva Gomes Source Type: research

Cold-induced anaphylaxis triggered by drinking cold water
We report the case of an 11-year-old boy previously diagnosed with chronic spontaneous urticaria who developed facial swelling, itchy hives, difficulty in breathing, vomiting and abdominal pain within 5 minutes of drinking cold water. He received a standard dose of non-sedating second-generation antihistamines at home. He was observed in the emergency room for 2 hours and discharged with an epinephrin autoinjector. During the subsequent outpatient clinic visit, an ice cube test was performed which confirmed the new diagnosis of comorbid cold-induced chronic urticaria. On further questioning, the parents reported occurrence...
Source: Allergologia et Immunopathologia - March 9, 2024 Category: Allergy & Immunology Authors: Abdulaziz S Alrafiaah Elena Netchiporouk Moshe Ben-Shoshan Source Type: research

Safety of direct oral provocation test to delabel reported mild beta-lactam allergy in infants
CONCLUSIONS: A direct DPT without prior tests is a safe and effective procedure to delabel BL allergy, even in infants. The authors wish to emphasize the importance of properly validating BL allergy suspicions by promoting appropriate diagnostic procedures in infants as, in most cases, DHRs can be excluded and there is no need for further therapeutic restrictions.PMID:38459885 | DOI:10.15586/aei.v52i2.887 (Source: Allergologia et Immunopathologia)
Source: Allergologia et Immunopathologia - March 9, 2024 Category: Allergy & Immunology Authors: Francisca Cunha In ês Cunha Eva Gomes Source Type: research

Cold-induced anaphylaxis triggered by drinking cold water
We report the case of an 11-year-old boy previously diagnosed with chronic spontaneous urticaria who developed facial swelling, itchy hives, difficulty in breathing, vomiting and abdominal pain within 5 minutes of drinking cold water. He received a standard dose of non-sedating second-generation antihistamines at home. He was observed in the emergency room for 2 hours and discharged with an epinephrin autoinjector. During the subsequent outpatient clinic visit, an ice cube test was performed which confirmed the new diagnosis of comorbid cold-induced chronic urticaria. On further questioning, the parents reported occurrence...
Source: Allergologia et Immunopathologia - March 9, 2024 Category: Allergy & Immunology Authors: Abdulaziz S Alrafiaah Elena Netchiporouk Moshe Ben-Shoshan Source Type: research

Safety of direct oral provocation test to delabel reported mild beta-lactam allergy in infants
CONCLUSIONS: A direct DPT without prior tests is a safe and effective procedure to delabel BL allergy, even in infants. The authors wish to emphasize the importance of properly validating BL allergy suspicions by promoting appropriate diagnostic procedures in infants as, in most cases, DHRs can be excluded and there is no need for further therapeutic restrictions.PMID:38459885 | DOI:10.15586/aei.v52i2.887 (Source: Allergologia et Immunopathologia)
Source: Allergologia et Immunopathologia - March 9, 2024 Category: Allergy & Immunology Authors: Francisca Cunha In ês Cunha Eva Gomes Source Type: research

Cold-induced anaphylaxis triggered by drinking cold water
We report the case of an 11-year-old boy previously diagnosed with chronic spontaneous urticaria who developed facial swelling, itchy hives, difficulty in breathing, vomiting and abdominal pain within 5 minutes of drinking cold water. He received a standard dose of non-sedating second-generation antihistamines at home. He was observed in the emergency room for 2 hours and discharged with an epinephrin autoinjector. During the subsequent outpatient clinic visit, an ice cube test was performed which confirmed the new diagnosis of comorbid cold-induced chronic urticaria. On further questioning, the parents reported occurrence...
Source: Allergologia et Immunopathologia - March 9, 2024 Category: Allergy & Immunology Authors: Abdulaziz S Alrafiaah Elena Netchiporouk Moshe Ben-Shoshan Source Type: research

Safety of direct oral provocation test to delabel reported mild beta-lactam allergy in infants
CONCLUSIONS: A direct DPT without prior tests is a safe and effective procedure to delabel BL allergy, even in infants. The authors wish to emphasize the importance of properly validating BL allergy suspicions by promoting appropriate diagnostic procedures in infants as, in most cases, DHRs can be excluded and there is no need for further therapeutic restrictions.PMID:38459885 | DOI:10.15586/aei.v52i2.887 (Source: Allergologia et Immunopathologia)
Source: Allergologia et Immunopathologia - March 9, 2024 Category: Allergy & Immunology Authors: Francisca Cunha In ês Cunha Eva Gomes Source Type: research