Molecules, Vol. 28, Pages 2680: Chemical Composition of Hazelnut Skin Food Waste and Protective Role against Advanced Glycation End-Products (AGEs) Damage in THP-1-Derived Macrophages
a De Gara
Glycation and the accumulation of advanced glycation end-products (AGEs) are known to occur during aging, diabetes and neurodegenerative diseases. Increased glucose or methylglyoxal (MGO) levels in the blood of diabetic patients result in increased AGEs. A diet rich in bioactive food compounds, like polyphenols, has a protective effect. The aim of this work is to evaluate the capacity of hazelnut skin polyphenolic extract to protect THP-1-macrophages from damage induced by AGEs. The main polyphenolic subclass was identified and quantified by means of HPLC/MS and the Folin–Ciocalteu method. AGEs ...
Source: Molecules - March 16, 2023 Category: Chemistry Authors: Ludovica Spagnuolo Susanna Della Posta Chiara Fanali Laura Dugo Laura De Gara Tags: Article Source Type: research
Prevalence of nut allergen sensitization among children in central Poland
CONCLUSIONS: Component-based diagnostics enables differentiation between primary and cross-reactive sensitization to nut allergens and detects co-sensitization. The clinical relevance of the latter observation is remarkable as co-sensitization increases the risk of life-threatening reactions even in trace nut contamination.PMID:36909898 | PMC:PMC9993204 | DOI:10.5114/ada.2022.124730 (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - March 13, 2023 Category: Dermatology Authors: Magdalena Chojnowska-W ójtowicz Klementyna Łyżwa Joanna Zieli ńska Wioletta Zag órska Katarzyna Grzela Source Type: research
