Impact of diet on CVD and diabetes mortality in Latin America and the Caribbean: a comparative risk assessment analysis.
CONCLUSIONS: Suboptimal intakes of commonly consumed foods were associated with substantial CMD mortality in LAC with significant heterogeneity across countries. Improved access to healthful foods, such as nuts and fruits, and limits in availability of unhealthful factors, such as processed foods, would reduce diet-related burdens of CMD in LAC.
PMID: 32489172 [PubMed - as supplied by publisher] (Source: Public Health Nutrition)
Source: Public Health Nutrition - June 2, 2020 Category: International Medicine & Public Health Authors: Sisa I, Abeyá-Gilardon E, Fisberg RM, Jackson MD, Mangialavori GL, Sichieri R, Cudhea F, Bannuru RR, Ruthazer R, Mozaffarian D, Singh GM Tags: Public Health Nutr Source Type: research
Evaluation of resistance to pyrethroid and organophosphate adulticides and kdr genotyping in Aedes aegypti populations from Roraima, the northernmost Brazilian State
Roraima, the northernmost State in Brazil, borders Venezuela and Guyana. Although mostly covered by the tropical forests, the urban centers of this state are highly infested with Ae. aegypti and are endemic for d... (Source: Parasites and Vectors)
Source: Parasites and Vectors - May 20, 2020 Category: Microbiology Authors: Ram ão Luciano Nogueira Hayd, Luana Carrara, Joel de Melo Lima, Nathalia Coelho Vargas de Almeida, José Bento Pereira Lima and Ademir Jesus Martins Tags: Research Source Type: research
Local emergence in Amazonia of < i > Plasmodium falciparum k13 < /i > C580Y mutants associated with < i > in vitro < /i > artemisinin resistance
We report that mutantpfk13 has emerged independently in Guyana, with genome analysis indicating an evolutionary origin distinct from Southeast Asia.Pfk13 C580Y parasites were observed in 1.6% (14/854) of samples collected in Guyana in 2016 –2017. Introducingpfk13 C580Y or R539T mutations by gene editing into local parasites conferred high levels ofin vitro artemisinin resistance.In vitro growth competition assays revealed a fitness cost associated with thesepfk13 variants, potentially explaining why these resistance alleles have not increased in frequency more quickly in South America. These data place local malaria cont...
Source: eLife - May 12, 2020 Category: Biomedical Science Tags: Epidemiology and Global Health Microbiology and Infectious Disease Source Type: research
A survey of self-reported research knowledge in Guyanese, Rwandan, Zambian, and Ethiopian anesthesia residents.
PMID: 32347458 [PubMed - as supplied by publisher] (Source: Canadian Journal of Anaesthesia)
Source: Canadian Journal of Anaesthesia - April 27, 2020 Category: Anesthesiology Authors: Bleeker H, Bould MD, Harvey A, Hamstra J, McIsaac DI Tags: Can J Anaesth Source Type: research
Venomics and antivenomics of the poorly studied Brazil’s lancehead, Bothrops brazili (Hoge, 1954), from the Brazilian State of Pará
Conclusion: The proteomics outcome contribute to a deeper insight into the spectrum of toxins present in the venom of the Brazil ’ s lancehead, and rationalize the pathophysiology underlying this snake bite envenomings. The comparative qualitative and quantitative immunorecognition profile of the Brazilian pentabothropic antivenom toward the venom toxins of B. brazili and B. jararaca (the reference venom for assessing the bothropic antivenom's potency in Brazil), provides clues about the proper use of the Brazilian antibothropic polyvalent antivenom in the treatment of bites by the Brazil ’ s lancehead. (Source: Journa...
Source: Journal of Venomous Animals and Toxins including Tropical Diseases - April 17, 2020 Category: Tropical Medicine Source Type: research
