Coffee and cigarettes: Modulation of high and low sensitivity α4β2 nicotinic acetylcholine receptors by n-MP, a biomarker of coffee consumption
Neuropharmacology. 2022 Jun 27;216:109173. doi: 10.1016/j.neuropharm.2022.109173. Online ahead of print.ABSTRACTSmokers report particular appreciation for coffee with their first cigarettes of the day. We investigated with voltage-clamp experiments, effects of aqueous extracts (coffees) of unroasted and roasted coffee beans on the activity of human brain nicotinic acetylcholine receptor (nAChR) subtypes expressed in Xenopus oocytes, looking at complex brews, low molecular weight (LMW) fractions, and specific compounds present in coffee. When co-applied with PNU-120596, a positive allosteric modulator (PAM), the coffees sti...
Source: Neuropharmacology - June 30, 2022 Category: Drugs & Pharmacology Authors: Roger L Papke Madison Karaffa Nicole A Horenstein Clare Stokes Source Type: research
Coffee and cigarettes: Modulation of high and low sensitivity α4β2 nicotinic acetylcholine receptors by n-MP, a biomarker of coffee consumption
Neuropharmacology. 2022 Jun 27;216:109173. doi: 10.1016/j.neuropharm.2022.109173. Online ahead of print.ABSTRACTSmokers report particular appreciation for coffee with their first cigarettes of the day. We investigated with voltage-clamp experiments, effects of aqueous extracts (coffees) of unroasted and roasted coffee beans on the activity of human brain nicotinic acetylcholine receptor (nAChR) subtypes expressed in Xenopus oocytes, looking at complex brews, low molecular weight (LMW) fractions, and specific compounds present in coffee. When co-applied with PNU-120596, a positive allosteric modulator (PAM), the coffees sti...
Source: Neuropharmacology - June 30, 2022 Category: Drugs & Pharmacology Authors: Roger L Papke Madison Karaffa Nicole A Horenstein Clare Stokes Source Type: research
Coffee and cigarettes: Modulation of high and low sensitivity α4β2 nicotinic acetylcholine receptors by n-MP, a biomarker of coffee consumption
Neuropharmacology. 2022 Jun 27;216:109173. doi: 10.1016/j.neuropharm.2022.109173. Online ahead of print.ABSTRACTSmokers report particular appreciation for coffee with their first cigarettes of the day. We investigated with voltage-clamp experiments, effects of aqueous extracts (coffees) of unroasted and roasted coffee beans on the activity of human brain nicotinic acetylcholine receptor (nAChR) subtypes expressed in Xenopus oocytes, looking at complex brews, low molecular weight (LMW) fractions, and specific compounds present in coffee. When co-applied with PNU-120596, a positive allosteric modulator (PAM), the coffees sti...
Source: Neuropharmacology - June 30, 2022 Category: Drugs & Pharmacology Authors: Roger L Papke Madison Karaffa Nicole A Horenstein Clare Stokes Source Type: research
Complementary food introduction practices in infants with intestinal failure
CONCLUSION: Institutional practices related to the introduction of CF to infants with IF vary. Similarities with first food choice and foods to avoid were observed. Evidenced-based practice guidelines for the introduction of CF to infants with IF need to be established to determine best practices for reducing stool output, encouraging weaning from parenteral nutrition, and achieving enteral autonomy.PMID:35762260 | DOI:10.1002/ncp.10883 (Source: Nutrition in Clinical Practice)
Source: Nutrition in Clinical Practice - June 28, 2022 Category: Nutrition Authors: Anita M Nucci Kate Samela Elizabeth Bobo Jacqueline Wessel ASPEN Pediatric Intestinal Failure Section Source Type: research
Complementary food introduction practices in infants with intestinal failure
CONCLUSION: Institutional practices related to the introduction of CF to infants with IF vary. Similarities with first food choice and foods to avoid were observed. Evidenced-based practice guidelines for the introduction of CF to infants with IF need to be established to determine best practices for reducing stool output, encouraging weaning from parenteral nutrition, and achieving enteral autonomy.PMID:35762260 | DOI:10.1002/ncp.10883 (Source: Nutrition in Clinical Practice)
Source: Nutrition in Clinical Practice - June 28, 2022 Category: Nutrition Authors: Anita M Nucci Kate Samela Elizabeth Bobo Jacqueline Wessel ASPEN Pediatric Intestinal Failure Section Source Type: research
