Garcinia Cambogia, Either Alone or in Combination with Green Tea Causes Moderate to Severe Liver Injury
Garcinia cambogia, either alone or with green tea, is commonly promoted for weight loss. Sporadic cases of liver failure from G. cambogia have been reported, but its role in liver injury is controversial. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - August 13, 2021 Category: Gastroenterology Authors: Raj Vuppalanchi, Herbert L. Bonkovsky, Jawad Ahmad, Huiman Barnhart, Francisco Durazo, Robert J. Fontana, Jiezhun Gu, Ikhlas Khan, David E. Kleiner, Christopher Koh, Don C. Rockey, Elizabeth J. Phillips, Yi-Ju Li, Jose Serrano, Andrew Stolz, Hans L. Tillm Source Type: research

Garcinia cambogia, Either Alone or in Combination With Green Tea, Causes Moderate to Severe Liver Injury
Garcinia cambogia, either alone or with green tea, is commonly promoted for weight loss. Sporadic cases of liver failure from G cambogia have been reported, but its role in liver injury is controversial. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - August 13, 2021 Category: Gastroenterology Authors: Raj Vuppalanchi, Herbert L. Bonkovsky, Jawad Ahmad, Huiman Barnhart, Francisco Durazo, Robert J. Fontana, Jiezhun Gu, Ikhlas Khan, David E. Kleiner, Christopher Koh, Don C. Rockey, Elizabeth J. Phillips, Yi-Ju Li, Jose Serrano, Andrew Stolz, Hans L. Tillm Source Type: research

< em > Garcinia cambogia < /em > attenuates adipogenesis by affecting CEBPB and SQSTM1/p62-mediated selective autophagic degradation of KLF3 through RPS6KA1 and STAT3 suppression
Autophagy. 2021 Jun 8:1-22. doi: 10.1080/15548627.2021.1936356. Online ahead of print.ABSTRACTThe overexpansion of adipose tissues leads to obesity and eventually results in metabolic disorders. Garcinia cambogia (G. cambogia) has been used as an antiobesity supplement. However, the molecular mechanisms underlying the effects of G. cambogia on cellular processes have yet to be fully understood. Here, we discovered that G. cambogia attenuated the expression of CEBPB (CCAAT/enhancer binding protein (C/EBP), beta), an important adipogenic factor, suppressing its transcription in differentiated cells. In addition, G. cambogia ...
Source: Autophagy - June 8, 2021 Category: Cytology Authors: Joo-Hui Han Keun-Woo Jang Chang-Seon Myung Source Type: research

< em > Garcinia cambogia < /em > attenuates adipogenesis by affecting CEBPB and SQSTM1/p62-mediated selective autophagic degradation of KLF3 through RPS6KA1 and STAT3 suppression
Autophagy. 2021 Jun 8:1-22. doi: 10.1080/15548627.2021.1936356. Online ahead of print.ABSTRACTThe overexpansion of adipose tissues leads to obesity and eventually results in metabolic disorders. Garcinia cambogia (G. cambogia) has been used as an antiobesity supplement. However, the molecular mechanisms underlying the effects of G. cambogia on cellular processes have yet to be fully understood. Here, we discovered that G. cambogia attenuated the expression of CEBPB (CCAAT/enhancer binding protein (C/EBP), beta), an important adipogenic factor, suppressing its transcription in differentiated cells. In addition, G. cambogia ...
Source: Autophagy - June 8, 2021 Category: Cytology Authors: Joo-Hui Han Keun-Woo Jang Chang-Seon Myung Source Type: research

Efficacy of a Novel Herbal Formulation (F2) on the Management of Obesity: < em > In Vitro < /em > and < em > In Vivo < /em > Study
CONCLUSION: The results revealed that the formulation F2 exhibited potential antiobesity activity through the inhibition of adipocyte differentiation, dietary fat absorption, and reduction of free fatty acids deposition in tissues.PMID:33628322 | PMC:PMC7884115 | DOI:10.1155/2021/8854915 (Source: Evidence-based Complementary and Alternative Medicine)
Source: Evidence-based Complementary and Alternative Medicine - February 25, 2021 Category: Complementary Medicine Authors: Prakash Raj Pandeya Ramakanta Lamichhane Kyung-Hee Lee Gopal Lamichhane Se-Gun Kim Hyun-Ju Jung Source Type: research

Garcinia cambogia and Glucomannan reduce weight, change body composition and ameliorate lipid and glucose blood profiles in overweight/obese patients
Publication date: Available online 8 January 2021Source: Journal of Herbal MedicineAuthor(s): Andrea Maia-Landim, Juan M. Ramírez, Carolina Lancho, María S. Poblador, José L. Lancho (Source: Journal of Herbal Medicine)
Source: Journal of Herbal Medicine - January 9, 2021 Category: Complementary Medicine Source Type: research

In silico studies reveal antiviral effects of traditional Indian spices on COVID-19.
CONCLUSION: Optimal use of traditional spices in our daily meals may help fight against COVID-19. This study also paves the path for herbal drug formulation against SARS-CoV-2 after wet lab validation. PMID: 33357192 [PubMed - as supplied by publisher] (Source: Current Pharmaceutical Design)
Source: Current Pharmaceutical Design - December 22, 2020 Category: Drugs & Pharmacology Authors: Kumar B, Zaidi S, Haque S, Dasgupta N, Hussain A, Unni S, Singh V, Mishra BN Tags: Curr Pharm Des Source Type: research

Molecules, Vol. 25, Pages 4452: Extracts from Eleutherococcus senticosus (Rupr. et Maxim.) Maxim. Roots: A New Hope Against Honeybee Death Caused by Nosemosis
In this study, we have tested extracts obtained from: Eleutherococcus senticosus, Garcinia cambogia, Panax ginseng, Ginkgo biloba, Schisandra chinensis, and Camellia sinensis. The 75% ethanol E. senticosus root extract proved to be the most effective, both as a cure and in the prophylaxis of nosemosis. Therefore, Eleutherococcus senticosus, and its active compounds, eleutherosides, are considered the most powerful adaptogens, in the pool of all extracts that were selected for screening, for supporting immunity and improving resistance of honeybees. The optimum effective concentration of 0.4 mg/mL E. senticosus extract resp...
Source: Molecules - September 27, 2020 Category: Chemistry Authors: Aneta A. Ptaszy ńska Daniel Za łuski Tags: Article Source Type: research