Dietary Supplement-Induced Hepatotoxicity: A Clinical Perspective
This article delves into the clinical perspective of DS-related hepatotoxicity, highlighting key concepts such as a systematic diagnostic approach. The discussion extends to notable examples of both currently popular and potential future dietary supplements, such as garcinia cambogia, turmeric, and ashwagandha, accompanied by an overview of recent findings. Causality assessment tools play a crucial role in establishing a connection between these products and instances of liver injury, with consideration of the advantages and disadvantages associated with their use. Fostering a comprehensive understanding of regulatory stan...
Source: Journal of Dietary Supplements - March 26, 2024 Category: Nutrition Authors: Jordan Carty Victor J Navarro Source Type: research
Hydroxycitric Acid Alleviated Lung Ischemia-Reperfusion Injury by Inhibiting Oxidative Stress and Ferroptosis through the Hif-1 α Pathway
Curr Issues Mol Biol. 2023 Dec 8;45(12):9868-9886. doi: 10.3390/cimb45120616.ABSTRACTLung ischemia-reperfusion injury (LIRI) is a prevalent occurrence in various pulmonary diseases and surgical procedures, including lung resections and transplantation. LIRI can result in systemic hypoxemia and multi-organ failure. Hydroxycitric acid (HCA), the primary acid present in the peel of Garcinia cambogia, exhibits anti-inflammatory, antioxidant, and anticancer properties. However, the effects of HCA on LIRI remain unknown. To investigate the impact of HCA on LIRI in mice, the mice were randomly divided into four groups: the contro...
Source: Current Issues in Molecular Biology - December 22, 2023 Category: Molecular Biology Authors: Zi-Long Lu Cong-Kuan Song Shi-Shi Zou Shi-Ze Pan Kai Lai Ning Li Qing Geng Source Type: research
Hydroxycitric Acid Alleviated Lung Ischemia-Reperfusion Injury by Inhibiting Oxidative Stress and Ferroptosis through the Hif-1 α Pathway
Curr Issues Mol Biol. 2023 Dec 8;45(12):9868-9886. doi: 10.3390/cimb45120616.ABSTRACTLung ischemia-reperfusion injury (LIRI) is a prevalent occurrence in various pulmonary diseases and surgical procedures, including lung resections and transplantation. LIRI can result in systemic hypoxemia and multi-organ failure. Hydroxycitric acid (HCA), the primary acid present in the peel of Garcinia cambogia, exhibits anti-inflammatory, antioxidant, and anticancer properties. However, the effects of HCA on LIRI remain unknown. To investigate the impact of HCA on LIRI in mice, the mice were randomly divided into four groups: the contro...
Source: Current Issues in Molecular Biology - December 22, 2023 Category: Molecular Biology Authors: Zi-Long Lu Cong-Kuan Song Shi-Shi Zou Shi-Ze Pan Kai Lai Ning Li Qing Geng Source Type: research
Hydroxycitric Acid Alleviated Lung Ischemia-Reperfusion Injury by Inhibiting Oxidative Stress and Ferroptosis through the Hif-1 α Pathway
Curr Issues Mol Biol. 2023 Dec 8;45(12):9868-9886. doi: 10.3390/cimb45120616.ABSTRACTLung ischemia-reperfusion injury (LIRI) is a prevalent occurrence in various pulmonary diseases and surgical procedures, including lung resections and transplantation. LIRI can result in systemic hypoxemia and multi-organ failure. Hydroxycitric acid (HCA), the primary acid present in the peel of Garcinia cambogia, exhibits anti-inflammatory, antioxidant, and anticancer properties. However, the effects of HCA on LIRI remain unknown. To investigate the impact of HCA on LIRI in mice, the mice were randomly divided into four groups: the contro...
Source: Current Issues in Molecular Biology - December 22, 2023 Category: Molecular Biology Authors: Zi-Long Lu Cong-Kuan Song Shi-Shi Zou Shi-Ze Pan Kai Lai Ning Li Qing Geng Source Type: research
Hydroxycitric Acid Alleviated Lung Ischemia-Reperfusion Injury by Inhibiting Oxidative Stress and Ferroptosis through the Hif-1 α Pathway
Curr Issues Mol Biol. 2023 Dec 8;45(12):9868-9886. doi: 10.3390/cimb45120616.ABSTRACTLung ischemia-reperfusion injury (LIRI) is a prevalent occurrence in various pulmonary diseases and surgical procedures, including lung resections and transplantation. LIRI can result in systemic hypoxemia and multi-organ failure. Hydroxycitric acid (HCA), the primary acid present in the peel of Garcinia cambogia, exhibits anti-inflammatory, antioxidant, and anticancer properties. However, the effects of HCA on LIRI remain unknown. To investigate the impact of HCA on LIRI in mice, the mice were randomly divided into four groups: the contro...
Source: Mol Biol Cell - December 22, 2023 Category: Molecular Biology Authors: Zi-Long Lu Cong-Kuan Song Shi-Shi Zou Shi-Ze Pan Kai Lai Ning Li Qing Geng Source Type: research
Hydroxycitric Acid Alleviated Lung Ischemia-Reperfusion Injury by Inhibiting Oxidative Stress and Ferroptosis through the Hif-1 α Pathway
Curr Issues Mol Biol. 2023 Dec 8;45(12):9868-9886. doi: 10.3390/cimb45120616.ABSTRACTLung ischemia-reperfusion injury (LIRI) is a prevalent occurrence in various pulmonary diseases and surgical procedures, including lung resections and transplantation. LIRI can result in systemic hypoxemia and multi-organ failure. Hydroxycitric acid (HCA), the primary acid present in the peel of Garcinia cambogia, exhibits anti-inflammatory, antioxidant, and anticancer properties. However, the effects of HCA on LIRI remain unknown. To investigate the impact of HCA on LIRI in mice, the mice were randomly divided into four groups: the contro...
Source: Current Issues in Molecular Biology - December 22, 2023 Category: Molecular Biology Authors: Zi-Long Lu Cong-Kuan Song Shi-Shi Zou Shi-Ze Pan Kai Lai Ning Li Qing Geng Source Type: research
Hydroxycitric Acid Alleviated Lung Ischemia-Reperfusion Injury by Inhibiting Oxidative Stress and Ferroptosis through the Hif-1 α Pathway
Curr Issues Mol Biol. 2023 Dec 8;45(12):9868-9886. doi: 10.3390/cimb45120616.ABSTRACTLung ischemia-reperfusion injury (LIRI) is a prevalent occurrence in various pulmonary diseases and surgical procedures, including lung resections and transplantation. LIRI can result in systemic hypoxemia and multi-organ failure. Hydroxycitric acid (HCA), the primary acid present in the peel of Garcinia cambogia, exhibits anti-inflammatory, antioxidant, and anticancer properties. However, the effects of HCA on LIRI remain unknown. To investigate the impact of HCA on LIRI in mice, the mice were randomly divided into four groups: the contro...
Source: Mol Biol Cell - December 22, 2023 Category: Molecular Biology Authors: Zi-Long Lu Cong-Kuan Song Shi-Shi Zou Shi-Ze Pan Kai Lai Ning Li Qing Geng Source Type: research
Hydroxycitric Acid Alleviated Lung Ischemia-Reperfusion Injury by Inhibiting Oxidative Stress and Ferroptosis through the Hif-1 α Pathway
Curr Issues Mol Biol. 2023 Dec 8;45(12):9868-9886. doi: 10.3390/cimb45120616.ABSTRACTLung ischemia-reperfusion injury (LIRI) is a prevalent occurrence in various pulmonary diseases and surgical procedures, including lung resections and transplantation. LIRI can result in systemic hypoxemia and multi-organ failure. Hydroxycitric acid (HCA), the primary acid present in the peel of Garcinia cambogia, exhibits anti-inflammatory, antioxidant, and anticancer properties. However, the effects of HCA on LIRI remain unknown. To investigate the impact of HCA on LIRI in mice, the mice were randomly divided into four groups: the contro...
Source: Current Issues in Molecular Biology - December 22, 2023 Category: Molecular Biology Authors: Zi-Long Lu Cong-Kuan Song Shi-Shi Zou Shi-Ze Pan Kai Lai Ning Li Qing Geng Source Type: research
Hydroxycitric Acid Alleviated Lung Ischemia-Reperfusion Injury by Inhibiting Oxidative Stress and Ferroptosis through the Hif-1 α Pathway
Curr Issues Mol Biol. 2023 Dec 8;45(12):9868-9886. doi: 10.3390/cimb45120616.ABSTRACTLung ischemia-reperfusion injury (LIRI) is a prevalent occurrence in various pulmonary diseases and surgical procedures, including lung resections and transplantation. LIRI can result in systemic hypoxemia and multi-organ failure. Hydroxycitric acid (HCA), the primary acid present in the peel of Garcinia cambogia, exhibits anti-inflammatory, antioxidant, and anticancer properties. However, the effects of HCA on LIRI remain unknown. To investigate the impact of HCA on LIRI in mice, the mice were randomly divided into four groups: the contro...
Source: Current Issues in Molecular Biology - December 22, 2023 Category: Molecular Biology Authors: Zi-Long Lu Cong-Kuan Song Shi-Shi Zou Shi-Ze Pan Kai Lai Ning Li Qing Geng Source Type: research
Hydroxycitric Acid Alleviated Lung Ischemia-Reperfusion Injury by Inhibiting Oxidative Stress and Ferroptosis through the Hif-1 α Pathway
Curr Issues Mol Biol. 2023 Dec 8;45(12):9868-9886. doi: 10.3390/cimb45120616.ABSTRACTLung ischemia-reperfusion injury (LIRI) is a prevalent occurrence in various pulmonary diseases and surgical procedures, including lung resections and transplantation. LIRI can result in systemic hypoxemia and multi-organ failure. Hydroxycitric acid (HCA), the primary acid present in the peel of Garcinia cambogia, exhibits anti-inflammatory, antioxidant, and anticancer properties. However, the effects of HCA on LIRI remain unknown. To investigate the impact of HCA on LIRI in mice, the mice were randomly divided into four groups: the contro...
Source: Current Issues in Molecular Biology - December 22, 2023 Category: Molecular Biology Authors: Zi-Long Lu Cong-Kuan Song Shi-Shi Zou Shi-Ze Pan Kai Lai Ning Li Qing Geng Source Type: research
