Fetal Alcohol Syndrome Disorder Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Juvenile Competency Complications: Protocol, Unmet Needs, Developmental Immaturity, FASD, and Comorbidity
Am J Law Med. 2023 Jul;49(2-3):173-192. doi: 10.1017/amj.2023.26. Epub 2024 Feb 12.ABSTRACTThis Article focuses on unifying the protocol for state competency evaluations, but with special concerns about undiagnosed FASD and developmental immaturity in adolescents. States do not mandate any process whereby psychometric tests are first performed prior to psychiatric mental status evaluations, often causing disparities in evaluations which might easily be avoided in court proceedings. Adding to the complications in current competency evaluations are recent studies from Canada and Australia identifying exceptionally high rates...
Source: American Journal of Law and Medicine - February 12, 2024 Category: Medical Law Authors: David R Katner Source Type: research

Optogenetic stimulation of corticostriatal circuits improves behavioral flexibility in mice with prenatal alcohol exposure
Neuropharmacology. 2024 Feb 7;247:109860. doi: 10.1016/j.neuropharm.2024.109860. Online ahead of print.ABSTRACTFetal alcohol spectrum disorder (FASD) is the most common preventable form of developmental and neurobehavioral disability. Animal models have demonstrated that even low to moderate prenatal alcohol exposure (PAE) is sufficient to impair behavioral flexibility in multiple domains. Previously, utilizing a moderate limited access drinking in the dark paradigm, we have shown that PAE 1) impairs touchscreen pairwise visual reversal in male adult offspring 2) leads to small but significant decreases in orbitofrontal (O...
Source: Neuropharmacology - February 9, 2024 Category: Drugs & Pharmacology Authors: Valentina Licheri Jayapriya Chandrasekaran Johnny A Kenton Clark W Bird C Fernando Valenzuela Jonathan L Brigman Source Type: research

GSE254846 Sex-Specific DNA Methylation and Gene Expression Changes in Mouse Placentas After Early Preimplantation Alcohol Exposure[RNA-Seq]
Contributors : Lisa-Marie Legault ; M élanie Breton-Larrivée ; Fannie Filion-Bienvenue ; Anthony Lemieux ; Alexandra Langford-Avelar ; Thomas Dupas ; Serge McGrawSeries Type : Expression profiling by high throughput sequencingOrganism :Preimplantation alcohol exposure can negatively impact embryonic development through disruption of molecular profiles and lead to fetal alcohol spectrum disorder (FASD). Despite the central role of the placenta in proper embryonic development and successful pregnancy, studies on the placenta in a FASD context are markedly lacking. Here, preimplantation binge-like alcohol exposure wa...
Source: GEO: Gene Expression Omnibus - February 7, 2024 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Source Type: research

GSE254845 Sex-Specific DNA Methylation and Gene Expression Changes in Mouse Placentas After Early Preimplantation Alcohol Exposure[Methyl-Seq]
Contributors : Lisa-Marie Legault ; M élanie Breton-Larrivée ; Fannie Filion-Bienvenue ; Anthony Lemieux ; Alexandra Langford-Avelar ; Thomas Dupas ; Serge McGrawSeries Type : Methylation profiling by high throughput sequencingOrganism :Preimplantation alcohol exposure can negatively impact embryonic development through disruption of molecular profiles and lead to fetal alcohol spectrum disorder (FASD). Despite the central role of the placenta in proper embryonic development and successful pregnancy, studies on the placenta in a FASD context are markedly lacking. Here, preimplantation binge-like alcohol exposure w...
Source: GEO: Gene Expression Omnibus - February 7, 2024 Category: Genetics & Stem Cells Tags: Methylation profiling by high throughput sequencing Source Type: research

Challenges and strengths experienced by fetal alcohol spectrum disorder diagnostic clinics in Canada
. (Source: Journal of Intellectual and Developmental Disability)
Source: Journal of Intellectual and Developmental Disability - January 18, 2024 Category: Disability Authors: Kelly D. HardingColleen BurnsChristine LafontaineAndrew WrathAlicia GroomKatherine FlanniganKathy UnsworthAudrey McFarlanea The Canada FASD Research Network, Vancouver, Canadab Department of Psychology, Laurentian University, Sudbury, Canadac Lakeland Cen Source Type: research

Caregivers' perspectives of support needs for adolescents with fetal alcohol spectrum disorder
AbstractResearch focused on fetal alcohol spectrum disorder (FASD) is often deficit-focused, limiting a holistic understanding of individuals' support needs. Families of adolescents with FASD also struggle to access appropriate services. Using semi-structured interviews, the current study explored the perspectives of seven caregivers of adolescents with FASD in Australia. Interpretative phenomenological analysis revealed that anxiety was perceived as a main barrier to participation for adolescents; however, incorporating adolescents' strengths facilitated participation. Additionally, caregivers described that professionals...
Source: Children and Society - January 11, 2024 Category: Child Development Authors: Kelly Skorka, Jodie Copley, Catherine McBryde, Pamela J. Meredith, Natasha Reid Tags: ORIGINAL ARTICLE Source Type: research

IJERPH, Vol. 21, Pages 85: Strong Born & mdash;A First of Its Kind National FASD Prevention Campaign in Australia Led by the National Aboriginal Community Controlled Health Organisation (NACCHO) in Collaboration with the Aboriginal Community Controlled Health Organisations (ACCHOs)
IJERPH, Vol. 21, Pages 85: Strong Born—A First of Its Kind National FASD Prevention Campaign in Australia Led by the National Aboriginal Community Controlled Health Organisation (NACCHO) in Collaboration with the Aboriginal Community Controlled Health Organisations (ACCHOs) International Journal of Environmental Research and Public Health doi: 10.3390/ijerph21010085 Authors: Robyn Williams Sarah Hayton Annabel Campbell Holly Kemp Dorothy Badry The Strong Born Campaign (2022&ndash;2025) was launched by the National Aboriginal Community Controlled Health Organisation (NACCHO) in 2023. Strong...
Source: International Journal of Environmental Research and Public Health - January 11, 2024 Category: Environmental Health Authors: Robyn Williams Sarah Hayton Annabel Campbell Holly Kemp Dorothy Badry Tags: Commentary Source Type: research

Long-term effects of low prenatal alcohol exposure on GABAergic interneurons of the murine posterior parietal cortex
CONCLUSIONS: These results suggest that impairments in cognitive control observed in FASD may be due to the significant reduction of parvalbumin-expressing GABAergic interneurons in the PPC. PAE animals may show compensatory changes in GABAergic function following developmental reduction of these interneurons.PMID:38151788 | DOI:10.1111/acer.15210 (Source: Cell Research)
Source: Cell Research - December 28, 2023 Category: Cytology Authors: Valentina Licheri Belkis J Jacquez Victoria K Castillo Dylan B Sainz C Fernando Valenzuela Jonathan L Brigman Source Type: research

Hesperidin Protects Alcohol-induced Mitochondrial Abnormalities via the Inhibition of Oxidative Stress and MPT Pore opening in Newborn Male Rats as Fetal Alcohol Syndrome Model
CONCLUSIONS: This study demonstrates that hesperidin exerts a potent mitochondria protective effect against alcohol-induced mitochondrial toxicity in FAS model. Moreover, these findings indicates that hesperidin might be a useful compound for prevention of alcohol-induced fetal developmental abnormalities during pregnancy.PMID:38147083 | DOI:10.15288/jsad.23-00243 (Source: Journal of Studies on Alcohol and Drugs)
Source: Journal of Studies on Alcohol and Drugs - December 26, 2023 Category: Addiction Authors: Zhaleh Jamali Ahmad Salimi Behzad Garmabi Saleh Khezri Mehdi Khaksari Source Type: research