Administrative Supplements for Equipment to Select NIGMS-Funded Awards
NIGMS is offering administrative supplements for equipment to select NIGMS-funded research projects or center/core facilities (NOT-GM-24-021). We welcome requests for single equipment systems that will advance the funded research of the parent project. Eligible investigators are strongly encouraged to discuss potential requests with the program officer of their parent award before submitting an application. The application deadline is February 15, 2024.
R01, R35, and R37 grantees:
Funds are available for the purchase of single equipment systems (to include components as necessary—e.g., for a working microscop...
Source: NIGMS Feedback Loop Blog - National Institute of General Medical Sciences - January 8, 2024 Category: Biomedical Science Authors: Chrissa Chverchko Tags: Funding Opportunities Resources Administrative Supplements Research Resources Source Type: blogs
PursueCare Completes Series B Fundraising Round and Acquires Digital Therapeutics Developed by Pear Therapeutics, Inc.
The Fundraising and Acquisition of Digital Therapeutics for SUD Strengthens PursueCare’s Ability to Provide Care for Individuals with Addiction
PursueCare, a digital addiction treatment provider, today announced the completion of a Series B fundraising round totaling $20 million. The Series B round was led by T.Rx Capital and Yamaha Motor Ventures, with participation from Seyen Capital and OCA Ventures. The proceeds from the financing will support PursueCare’s ongoing collaborative care initiatives with health systems across 11 states, as well as expansion into value-based care with Medicaid managed care and other heal...
Source: EMR and HIPAA - January 5, 2024 Category: Information Technology Authors: Healthcare IT News Tags: Health IT Company Healthcare IT Corey McCann Health IT Acquisitions Healthcare M&A Nicholas Mercadante OCA Ventures Pear Therapeutics PursueCare reSET reSET-O Seyen Capital T.Rx Capital Yamaha Motor Ventures Source Type: blogs
Health Equity – 2024 Health IT Predictions
As we kick off 2024, we wanted to start the new year with a series of 2024 Health IT predictions. We asked the Healthcare IT Today community to submit their predictions and we received a wide ranging set of responses that we grouped into a number of themes. In fact, we got so many that we had to narrow them down to just the best and most interesting. Check out our community’s predictions below and be sure to add your own thoughts and/or places you disagree with these predictions in the comments and on social media.
All of this year’s 2024 health IT predictions (updated as they’re shared):
John and ...
Source: EMR and HIPAA - January 2, 2024 Category: Information Technology Authors: John Lynn Tags: C-Suite Leadership Health IT Company Healthcare IT Hospital - Health System Regulations 2024 Health IT Predictions 86Borders Ali Modaressi Alice Wei Barnes & Thornburg Blue Shield of California BluePath Health Chris Bove CleanSla Source Type: blogs
Welcome To 2024 - I Hope It Is A Good One!
Welcome one and all to the New Year!While all sorts of platitudes are possible what I would really like to see over the next 12 months is some real accountability for the expenditure of Digital Health budgets so that, come December, we find the health system is working more smoothly and safely than at the start of the year and that better decisions are being made regarding patient care (Source: Australian Health Information Technology)
Source: Australian Health Information Technology - January 1, 2024 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs
Fight Aging! Newsletter, December 25th 2023
This study generates a comprehensive single-cell transcriptomic atlas of human atherosclerosis including 118,578 high-quality cells from atherosclerotic coronary and carotid arteries. By performing systematic benchmarking of integration methods, we mitigated data overcorrection while separating major cell lineages. Notably, we define cell subtypes that have not been previously identified from individual human atherosclerosis scRNA-seq studies.
Besides characterizing granular cell-type diversity and communication, we leverage this atlas to provide insights into smooth muscle cell (SMC) modulation. We integrate genome...
Source: Fight Aging! - December 24, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Modeling the Financials of a Drug to Treat Aging
We live in the world in which the regulatory costs imposed on the development of new medicine are enormous. This leads to centralization and regulatory capture. Only the largest entities, the Big Pharma companies, have the funds needed to satisfy the demands of regulators. These companies exist in synergy with the regulators, guiding the regulators (and the politicians backing them) to ensure that (a) their revenue streams are large and stable, and (b) there are fewer challenges to those revenue streams. Big Pharma entities are easily viewed through a cynical lens because their "treating the world, improving lives" rhetori...
Source: Fight Aging! - December 19, 2023 Category: Research Authors: Reason Tags: Longevity Industry Source Type: blogs
SEMCAP Health Continues Strategic Investment in SafeRide Health and Secures Memorial Hermann Health System Co-Investment
Recent Series C Financing of Leading Non-Emergency Medical Transportation Platform Fuels Rapid National Expansion
SEMCAP Health announces its continued support of portfolio company, SafeRide Health, with participation in the company’s recently announced Series C funding. This follows SEMCAP Health’s November 2021 initial investment in SafeRide Health, the leading network optimization platform for Non-Emergency Medical Transportation (NEMT). SafeRide Health’s ability to improve member experience and reduce costs for Medicaid and Medicare Advantage beneficiaries also attracted a strategic investment from Memorial Herm...
Source: EMR and HIPAA - November 27, 2023 Category: Information Technology Authors: Healthcare IT News Tags: Health IT Company Healthcare IT Feby Abraham Health IT Funding Health IT Fundings Health IT Investment Memorial Hermann Memorial Hermann Health System Ralph Muller Robbins Schrader SafeRide Health SEMCAP SEMCAP Health Vic Kats Source Type: blogs
Fight Aging! Newsletter, November 20th 2023
In this study, we attempted to further explain the role, exact mechanism and target of ICA in treating AD from the ferroptosis perspective. We found that ICA could improve the neurobehavioral, memory, and motor abilities of AD mice. It could lower the ferroptosis level and enhance the resistance to oxidative stress. After inhibition of MDM2, ICA could no longer improve the cognitive ability of AD mice, nor could it further inhibit ferroptosis. Network pharmacological analysis revealed that MDM2 might be the target of ICA action.
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Particulate Air Pollution and Its Effects on the Mechan...
Source: Fight Aging! - November 19, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
What Can Be Learned About Energy Metabolism and Longevity from Birds?
Here find an interesting commentary on some of the evolved genetic differences between mammals and birds, with a focus on genes relevant to energy metabolism - and potentially to species longevity. Larger animals live longer, but birds tend to be long-lived for their size. This is also the case for some bat species. It is thought that adaptations to energy metabolism needed to support the very energy-intensive activity of flight are involved in this increased longevity, providing resilience as a side effect.
The details have yet to be mapped in any comprehensive way, but studies such as today's open access example a...
Source: Fight Aging! - November 17, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
The Slow Spread of Off-Label Use for Treatments Shown to Target Mechanisms of Aging
A small number of low-cost and generic drugs have extensive human use and safety data, but also a sizable, compelling body of animal study evidence to suggest a likely modest slowing of aging, e.g. rapamycin, or that demonstrates the ability to target a mechanism of aging to reverse age-related disease, e.g. the dasatinib and quercetin, shown to selectively destroy senescent cells. In the US any drug approved for a given use can also be used off-label to treat other conditions. In principle the drug can be prescribed by any physician in this way. This is legal, though tends to require a slow bootstrapping process of educat...
Source: Fight Aging! - November 14, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Medicare and Social Security
Since it was a Krugzilla column about the Republican plan to drastically cut Medicare and Social Security benefits, I ' ll let the Krug answer the people who say " But we have to cut these programs, we can ' t afford them, what are the Democrats going to do about it? "Here ' s your gift link. By all means do read, but let me summarize the main points. First, regarding Social Security, the rise in cost resulting from the Baby Boomers retiring and the general aging of the population will actually be pretty modest, from about 4.9% of GDP today to 6.4% in 2052, according to CBO projections. And that ' s assuming that life...
Source: Stayin' Alive - October 30, 2023 Category: American Health Source Type: blogs
Worldwide Trends in Healthy versus Unhealthy Remaining Life Expectancy at 60
Human life expectancy has been trending upwards, slowly, for a very long time. Life expectancy at birth is influenced by a great many factors that have little to do with aging, and so is much less interesting than, say, life expectancy at 60. At present, that number increases by one year with every passing decade. This has been the case in an environment in which essentially nothing was being done to deliberately target underlying mechanisms of aging. The trend is an incidental side-effect of, most likely, (a) better life-long control over the burden of infectious disease, and (b) general improvements in the ability to tre...
Source: Fight Aging! - October 20, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Virgin Pulse and HealthComp Announce Intent to Merge to Create Comprehensive Employer Health Platform
Joining Forces to Improve Health Outcomes, Lower Costs, and Empower Members Through a Next-Generation Health Technology and Data Platform
New Mountain Capital, Marlin Equity Partners, Blackstone, and Morgan Health to Back Combined Entity, the Industry’s First Health Platform-as-a-Service
Virgin Pulse, a leading global digital-first health, wellbeing, and navigation company, today announced its intent to merge with HealthComp, a next-generation benefits and analytics platform. The merger will create a technology and data-powered health platform-as-a-service organization poised to tackle some of the industry’s biggest c...
Source: EMR and HIPAA - October 13, 2023 Category: Information Technology Authors: Healthcare IT News Tags: Health IT Company Healthcare IT Blackstone Chad Harris Chris Michalak Dan Mendelson Evercore® Health IT Acquisitions Healthcare M&A HealthComp J.P. Morgan Securities LLC JPMorgan Chase Kirkland & Ellis LLP Kyle Peterson Marlin Source Type: blogs
Fight Aging! Newsletter, October 9th 2023
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter,
please visit:
https://www.fightaging.org/newsletter/
Longevity Industry Consulting Services
Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - October 8, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Gardner Treadmill Protocol
Gardner Treadmill Protocol, also known as Gardner-Skinner Protocol was described in 1991 [1]. It is used mainly in the evaluation of peripheral arterial disease. The seminal article evaluated the effect of handrail support on claudication distance. Handrail support reduces energy cost of treadmill walking, and can affect claudication distance and hemodynamic responses in persons with peripheral vascular disease. Reliability of tests may also be reduced unless same pressure is applied to the handrails over repeated tests.
Gardner treadmill protocol is a symptom limited one with progressive graded workload having constant s...
Source: Cardiophile MD - October 6, 2023 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs
