Efficacy and safety of HIP1601 (dual delayed-release esomeprazole) 40 mg in erosive esophagitis compared to HGP1705 (delayed-release esomeprazole) 40 mg: a multicenter, randomized, double-blind, non-inferiority study
This study aime... (Source: BMC Gastroenterology)
Source: BMC Gastroenterology - December 18, 2023 Category: Gastroenterology Authors: Hyun Lim, Jong Kyu Park, Hyunsoo Chung, Si Hyung Lee, Jae Myung Park, Jung Ho Park, Gwang Ha Kim, Sung Kwan Shin, Su Jin Hong, Kwang Jae Lee, Moo In Park, Hye-Kyung Jung, Hyun-Soo Kim, Jae Kyu Sung, Seong Woo Jeon, Suck Chei Choi & hellip; Tags: Research Source Type: research

Acid ‐suppressive drugs: A systematic review and network meta‐analysis of their nocturnal acid‐inhibitory effect
ConclusionsThis is the first study to compare the effect of ASDs on inhibiting nocturnal acid breakthrough. Overall, in terms of nocturnal acid-inhibitory effect, vonoprazan and tegoprazan had an advantage against other regimens including H2RAs, isomer PPIs, traditional PPIs, AHB, and new PPIs. Even in some subgroups, such as language classification (English), types of study design (crossover-RCT), age ( ≤40 years), BMI (18.5-24.9 kg/m2), continent (Asia and North America), disease status (health), the duration of therapy (2  weeks), and time of administration (at daytime or at night-time), the nocturnal acid-inhibit...
Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - December 5, 2023 Category: Drugs & Pharmacology Authors: Shupeng Zou, Mengling Ouyang, Qian Cheng, Xuan Shi, Minghui Sun Tags: RESEARCH ARTICLE Source Type: research

Assessing the hypolipidemic and gastro-liver protective activity of herbal combination with emphasis on PPI amid selected multiple antihypertensive drug combination in experimental animal models
CONCLUSIONS: CThis investigation reported that antihypertensive drugs did not produce gastrointestinal (GI) toxicity, and the morphological structure of the organ was not changed. So, it could be concluded that the herbal combination used in this experiment has a promising role in controlling lipid profile, liver function, and antiulcer effects. Moreover, multiple drug therapy for hypertension does not cause any harm to the stomach. Further investigations might be carried out on a larger scale to make these statements more valid.PMID:38039033 | DOI:10.26355/eurrev_202311_34471 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - December 1, 2023 Category: Drugs & Pharmacology Authors: R P Monisa A K Azad I Rahma J T Israt A Shopnil A K Ayaz U H Taqweem T Aziz A Metab H A Thamer F A Abdullah Source Type: research

Assessing the hypolipidemic and gastro-liver protective activity of herbal combination with emphasis on PPI amid selected multiple antihypertensive drug combination in experimental animal models
CONCLUSIONS: CThis investigation reported that antihypertensive drugs did not produce gastrointestinal (GI) toxicity, and the morphological structure of the organ was not changed. So, it could be concluded that the herbal combination used in this experiment has a promising role in controlling lipid profile, liver function, and antiulcer effects. Moreover, multiple drug therapy for hypertension does not cause any harm to the stomach. Further investigations might be carried out on a larger scale to make these statements more valid.PMID:38039033 | DOI:10.26355/eurrev_202311_34471 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - December 1, 2023 Category: Drugs & Pharmacology Authors: R P Monisa A K Azad I Rahma J T Israt A Shopnil A K Ayaz U H Taqweem T Aziz A Metab H A Thamer F A Abdullah Source Type: research

Assessing the hypolipidemic and gastro-liver protective activity of herbal combination with emphasis on PPI amid selected multiple antihypertensive drug combination in experimental animal models
CONCLUSIONS: CThis investigation reported that antihypertensive drugs did not produce gastrointestinal (GI) toxicity, and the morphological structure of the organ was not changed. So, it could be concluded that the herbal combination used in this experiment has a promising role in controlling lipid profile, liver function, and antiulcer effects. Moreover, multiple drug therapy for hypertension does not cause any harm to the stomach. Further investigations might be carried out on a larger scale to make these statements more valid.PMID:38039033 | DOI:10.26355/eurrev_202311_34471 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - December 1, 2023 Category: Drugs & Pharmacology Authors: R P Monisa A K Azad I Rahma J T Israt A Shopnil A K Ayaz U H Taqweem T Aziz A Metab H A Thamer F A Abdullah Source Type: research

Assessing the hypolipidemic and gastro-liver protective activity of herbal combination with emphasis on PPI amid selected multiple antihypertensive drug combination in experimental animal models
CONCLUSIONS: CThis investigation reported that antihypertensive drugs did not produce gastrointestinal (GI) toxicity, and the morphological structure of the organ was not changed. So, it could be concluded that the herbal combination used in this experiment has a promising role in controlling lipid profile, liver function, and antiulcer effects. Moreover, multiple drug therapy for hypertension does not cause any harm to the stomach. Further investigations might be carried out on a larger scale to make these statements more valid.PMID:38039033 | DOI:10.26355/eurrev_202311_34471 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - December 1, 2023 Category: Drugs & Pharmacology Authors: R P Monisa A K Azad I Rahma J T Israt A Shopnil A K Ayaz U H Taqweem T Aziz A Metab H A Thamer F A Abdullah Source Type: research

Assessing the hypolipidemic and gastro-liver protective activity of herbal combination with emphasis on PPI amid selected multiple antihypertensive drug combination in experimental animal models
CONCLUSIONS: CThis investigation reported that antihypertensive drugs did not produce gastrointestinal (GI) toxicity, and the morphological structure of the organ was not changed. So, it could be concluded that the herbal combination used in this experiment has a promising role in controlling lipid profile, liver function, and antiulcer effects. Moreover, multiple drug therapy for hypertension does not cause any harm to the stomach. Further investigations might be carried out on a larger scale to make these statements more valid.PMID:38039033 | DOI:10.26355/eurrev_202311_34471 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - December 1, 2023 Category: Drugs & Pharmacology Authors: R P Monisa A K Azad I Rahma J T Israt A Shopnil A K Ayaz U H Taqweem T Aziz A Metab H A Thamer F A Abdullah Source Type: research

Assessing the hypolipidemic and gastro-liver protective activity of herbal combination with emphasis on PPI amid selected multiple antihypertensive drug combination in experimental animal models
CONCLUSIONS: CThis investigation reported that antihypertensive drugs did not produce gastrointestinal (GI) toxicity, and the morphological structure of the organ was not changed. So, it could be concluded that the herbal combination used in this experiment has a promising role in controlling lipid profile, liver function, and antiulcer effects. Moreover, multiple drug therapy for hypertension does not cause any harm to the stomach. Further investigations might be carried out on a larger scale to make these statements more valid.PMID:38039033 | DOI:10.26355/eurrev_202311_34471 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - December 1, 2023 Category: Drugs & Pharmacology Authors: R P Monisa A K Azad I Rahma J T Israt A Shopnil A K Ayaz U H Taqweem T Aziz A Metab H A Thamer F A Abdullah Source Type: research

Assessing the hypolipidemic and gastro-liver protective activity of herbal combination with emphasis on PPI amid selected multiple antihypertensive drug combination in experimental animal models
CONCLUSIONS: CThis investigation reported that antihypertensive drugs did not produce gastrointestinal (GI) toxicity, and the morphological structure of the organ was not changed. So, it could be concluded that the herbal combination used in this experiment has a promising role in controlling lipid profile, liver function, and antiulcer effects. Moreover, multiple drug therapy for hypertension does not cause any harm to the stomach. Further investigations might be carried out on a larger scale to make these statements more valid.PMID:38039033 | DOI:10.26355/eurrev_202311_34471 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - December 1, 2023 Category: Drugs & Pharmacology Authors: R P Monisa A K Azad I Rahma J T Israt A Shopnil A K Ayaz U H Taqweem T Aziz A Metab H A Thamer F A Abdullah Source Type: research

Assessing the hypolipidemic and gastro-liver protective activity of herbal combination with emphasis on PPI amid selected multiple antihypertensive drug combination in experimental animal models
CONCLUSIONS: CThis investigation reported that antihypertensive drugs did not produce gastrointestinal (GI) toxicity, and the morphological structure of the organ was not changed. So, it could be concluded that the herbal combination used in this experiment has a promising role in controlling lipid profile, liver function, and antiulcer effects. Moreover, multiple drug therapy for hypertension does not cause any harm to the stomach. Further investigations might be carried out on a larger scale to make these statements more valid.PMID:38039033 | DOI:10.26355/eurrev_202311_34471 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - December 1, 2023 Category: Drugs & Pharmacology Authors: R P Monisa A K Azad I Rahma J T Israt A Shopnil A K Ayaz U H Taqweem T Aziz A Metab H A Thamer F A Abdullah Source Type: research