Metabolic Barriers to Effective Cancer Immunotherapy
NCI ’ s Center for Cancer Research (CCR) Grand Rounds Dr. Delgoffe is a tenured Associate Professor of Immunology at the University of Pittsburgh School of Medicine and the University of Pittsburgh Medical Center Hillman Cancer Center. Dr. Delgoffe graduated summa cum laude from Western Michigan University in 2004 before completing doctoral training at the Johns Hopkins School of Medicine in 2010. His Ph.D research, under the direction of Dr. Jonathan Powell, made seminal discoveries regarding the role of nutrient sensing in T cell function and fate, resulting in several first-author contributions in high impact journals...
Source: Videocast - All Events - December 2, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video

NIH Council of Councils - January 2020
The NIH Council of Councils advises the NIH Director on on the policies and activities of the Division of Program Coordination, Planning, and Strategic Initiatives (DPCPSI) in the Office of the Director, NIH. The Council also carries out concept clearance for grant programs proposed by the DPCPSI Office of Research Infrastructure Programs (ORIP) and the NIH Common Fund, and conducts second-level review of proposed ORIP grant awards, awards for the Common Fund High-Risk, High-Reward Research Program, and awards for the Environmental influences on Child Health Outcomes and All of Us Research Programs.For more information go ...
Source: Videocast - All Events - November 22, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video

Spadefoot toads fooled biologists for years, and now the species offers new insights on adaptive ...
Spadefoot toads are master "shape-shifters," able to make drastic changes to their form and behavior in response to their environment. They're excellent candidates for research on plasticity in nature, or the ability of an organism to adapt to environmental changes or differences in habitats. With ...This is an NSF Multimedia Gallery item. (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - October 25, 2019 Category: Science Source Type: video

Human-Animal Interactions in the Research Environment (Day 1)
This workshop will explore and characterize aspects of the complex scientific, ethical, and occupational health issues associated with human-animal interactions in the biomedical research environment. The workshop will consider the full range of people who are involved in animal care and use in biomedical research settings, including research scientists, their staff and students, laboratory animal facilities managers, animal care staff, veterinarians and members of Institutional Animal Care and Use Committees (IACUCs). This workshop will also consider possible metrics that, in combination with other contextual information,...
Source: Videocast - All Events - October 16, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video

Human-Animal Interactions in the Research Environment (Day 2)
This workshop will explore and characterize aspects of the complex scientific, ethical, and occupational health issues associated with human-animal interactions in the biomedical research environment. The workshop will consider the full range of people who are involved in animal care and use in biomedical research settings, including research scientists, their staff and students, laboratory animal facilities managers, animal care staff, veterinarians and members of Institutional Animal Care and Use Committees (IACUCs). This workshop will also consider possible metrics that, in combination with other contextual information,...
Source: Videocast - All Events - October 16, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video

Human-Animal Interactions in the Research Environment
This workshop will explore and characterize aspects of the complex scientific, ethical, and occupational health issues associated with human-animal interactions in the biomedical research environment. The workshop will consider the full range of people who are involved in animal care and use in biomedical research settings, including research scientists, their staff and students, laboratory animal facilities managers, animal care staff, veterinarians and members of Institutional Animal Care and Use Committees (IACUCs). This workshop will also consider possible metrics that, in combination with other contextual information,...
Source: Videocast - All Events - October 15, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video

A two act play: the character of cells and the role of biomechanics
NIH Director's Wednesday Afternoon Lecture Series Dr. Barabino ’ s research interests are primarily focused on cellular and tissue responses to fluid mechanical forces in the context of vascular disease and orthopedic tissue engineering. She concentrates on the characterization and quantification of mechanical and biochemical cues that influence tissue growth and disease progression. Her interdisciplinary work incorporates biology, materials science and engineering toward novel therapeutic strategies to improve the health of individuals suffering with sickle cell disease and those suffering with diseases associated with ...
Source: Videocast - All Events - October 10, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video

Scalable platforms for generating RNA sensors and controllers
NIH Director's Wednesday Afternoon Lecture Series DeWitt Stetten, Jr. Lecture Biosensors are key components in engineered biological systems that interface with the large biochemical space in living cells and their environment. Aptamers, functional nucleic acid molecules that bind ligands, provide a powerful sensing element for many classes of molecules of interest. Although procedures such as SELEX have been quite successful in generating individual aptamers that bind proteins, generating small molecule aptamers has been more challenging due to the need to chemically modify the ligand to permit the recovery of binding seq...
Source: Videocast - All Events - October 10, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video

mHabitat tackling the complexity of implementing tech across healthcare
mHabitat founder Victoria Betton details the process of introducing technology in challenging healthcare environments. (Source: Healthcare ITNews Videos)
Source: Healthcare ITNews Videos - October 8, 2019 Category: Information Technology Tags: Medical Devices Quality and Safety Telehealth Women In Health IT Source Type: video

Informatics for Genomics-informed Surveillance of RNA Viruses
NLM Informatics and Data Science Lecture Series Genomics-informed surveillance is now recognized as an important extension to the monitoring of rapidly evolving pathogens. Next generation sequencing has the ability to produce large amounts of data for tracking viruses of public health importance. Biomedical informatics approaches are able to facilitate the translation of these data into information for public health surveillance. Thus, epidemiologists can identify new outbreaks or monitor the course of a known epidemic by leveraging pathogen sequences (and corresponding metadata) generated from the clinical specimens of si...
Source: Videocast - All Events - October 1, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video

Protocol Navigation Training - BTRIS: Translating Data into Results
Discussion will follow the talk. NIH staff and contractors can subscribe to the NIH Protocol Navigation List-serv to receive informational emails about the Program and to connect with other community members interested in protocol navigation: https://list.nih.gov/cgi-bin/wa.exe?A0=protocol-navigationAir date: 10/3/2019 12:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - September 25, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video

Brief Prevention Interventions for Young Adults: Strengthening Effects (Day 2)
College age remains a significant risk period for hazardous/extreme drinking among males and females. Recent data suggests that while drinking patterns are converging across sexes, college-age females are engaging in greater levels of binge drinking. Although brief interventions (BI) designed to reduce alcohol consumption and related harms in college and young adult populations have shown positive effects, the rigor of research on this topic has been impaired by limited outcome measurement, measurement inconsistencies, variability in methodologies, and modest effect sizes. There is a paucity of studies that use comparative...
Source: Videocast - All Events - September 16, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video

Brief Prevention Interventions for Young Adults: Strengthening Effects (Day 1)
College age remains a significant risk period for hazardous/extreme drinking among males and females. Recent data suggests that while drinking patterns are converging across sexes, college-age females are engaging in greater levels of binge drinking. Although brief interventions (BI) designed to reduce alcohol consumption and related harms in college and young adult populations have shown positive effects, the rigor of research on this topic has been impaired by limited outcome measurement, measurement inconsistencies, variability in methodologies, and modest effect sizes. There is a paucity of studies that use comparativ...
Source: Videocast - All Events - September 16, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video

Pain in Animals Workshop 2019: Cross-species measurement of acute pain (Day 2)
Millions of Americans suffer acute pain every year and use of naturally occurring models of acute pain in animals could contribute to the translational paradigm, and accelerate the discovery of effective, non-opioid analgesic options. However, to do this successfully, we need to be able to accurately measure acute pain in animals. Additionally, acute pain suffered by all animals is a welfare concern; inadequate pain control can negatively affect the human animal bond; and pain in farm animals may negatively impact the animal ’ s ability to maintain normal productivity. The cost, time, and practical application of analge...
Source: Videocast - All Events - September 11, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video

Pain in Animals Workshop 2019: Cross-species measurement of acute pain (Day 1)
Millions of Americans suffer acute pain every year and use of naturally occurring models of acute pain in animals could contribute to the translational paradigm, and accelerate the discovery of effective, non-opioid analgesic options. However, to do this successfully, we need to be able to accurately measure acute pain in animals. Additionally, acute pain suffered by all animals is a welfare concern; inadequate pain control can negatively affect the human animal bond; and pain in farm animals may negatively impact the animal ’ s ability to maintain normal productivity. The cost, time, and practical application of analge...
Source: Videocast - All Events - September 11, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video