Optimizing Outcomes for Patients with Chronic Illnesses and Disabilities
This presentation has three themes. Its overall theme focuses on improving health professionals ’ scientists ’ and policy makers ’ awareness of patients ’ lived experiences of chronic health needs whether in the clinic or in the home and work environment. By doing so all parties can make the best possible contribution to optimizing outcomes for tens of millions of Americans with chronic health needs. The second theme focus is on improving the understanding of various NIH constituencies on what can and must be done to accommodate patients and their caregivers in the clinical and research environments. The third area...
Source: Videocast - All Events - December 14, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
IIG seminar - Neutrophils: acute responders in chronic inflammatory diseases
Dr. Kaplan's research has focused on identifying mechanisms of immune dysregulation, organ damage, and premature vascular disease in systemic autoimmunity. More specifically, she investigates how innate immunity (in particular, type I interferons and myeloid cells) promote autoimmune responses and end-organ damage in systemic lupus erythematosus, rheumatoid arthritis, and other systemic autoimmune diseases. Recently, her research has focused on identifying abnormalities of neutrophil subsets, aberrant myeloid immunometabolism and the role of neutrophil extracellular traps (NETs) in systemic autoimmune disorders and chronic...
Source: Videocast - All Events - December 12, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
Sensing Inflammation in the Skin and Beyond
The type 2 immune response has evolved to arm the mammalian host with the capacity to expel parasites and noxious environmental substances from barrier surfaces. One critical aspect of this defense mechanism is stimulating protective behavioral responses such as coughing, sneezing, and scratching. Increasingly, it is appreciated that cytokines associated with type 2 immunity such as IL-4, IL-13, and IL-31 play critical roles in triggering mechanical reflexes like itch via direct interactions with sensory neurons. However, the tissue- and cell-specific manner in which these cytokines imprint unique sensory and neuroinflamma...
Source: Videocast - All Events - November 22, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
How does the Plasma Membrane Participate in Receptor-Mediated Cell Signaling?
Cells are poised to respond to their physical environment and must distinguish specific stimuli from biological noise. Specific response mechanisms depend on collective molecular interactions that are regulated in time and space by the plasma membrane and its connections with the cytoskeleton and intracellular structures. Molecular stimuli engage their specific receptors to initiate a transmembrane signal, and the surrounding system efficiently rearranges to amplify this nanoscale interaction to microscale assemblies, yielding a cellular response that often reaches to longer length scales within the organism. A striking ex...
Source: Videocast - All Events - November 21, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
Genetics at the maternal-placental-fetal interface: insights into fetal growth and cardiometabolic health.
The early life period is critical for long term health. Fetal growth abnormalities and cardiometabolic diseases are interconnected and cause high burden of morbidity. Understanding the complex genetic and environmental factors that underlie these relationships is crucial to developing preventive and therapeutic interventions for maximizing health across the life span. The placenta is critical for fetal development and potentially underlies later onset diseases, but it is understudied. Moreover, to date, perinatal genomic studies have failed to capture human ancestral diversity, which impedes biological understanding of dis...
Source: Videocast - All Events - November 8, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
WALS: Climate, Humans, and The Fate of the American Megafauna
Beth Alison Shapiro is a professor in the Department of Ecology and Evolutionary Biology at the University of California, Santa Cruz. Shapiro's work has centered on the analysis of ancient DNA. She was awarded a MacArthur Fellowship in 2009 and a Royal Society University Research Fellowship in 2006.Research InterestsMy research aims to better understand how populations and species change through time, in particular in in response to environmental and other changes to their habitat. To address this, my group uses the latest experimental and computational approaches to analyze genetic information isolated from fossil and arc...
Source: Videocast - All Events - November 7, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
2023 Stephen E. Straus Lecture: Novel Insights Into Heart-Brain Interactions and Neurobiological Resilience
Ahmed Tawakol, M.D., Massachusetts General Hospital and Harvard Medical School, will deliver the 2023 Stephen E. Straus Distinguished Lecture in the Science of Complementary Therapies. In his talk, Dr. Tawakol will review how neural pathways related to stress and depression result in cardiovascular diseases. Many studies have shown that stress and depression are associated with heightened amygdalar activity relative to regulatory activity in the cortex. Multisystem research has shown that increased stress-neural network activity triggers sympathetic system activity and induces leukopoiesis, resulting in systemic inflammati...
Source: Videocast - All Events - October 24, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
WALS Lecture: Laura Niedernhofer Ph.D.
Laura Niedernhofer joined the University of Minnesota in July 2018 to direct the new Institute on the Biology of Aging& Metabolism ;(external link)(iBAM) and Medical Discovery Team on the Biology of Aging. She is also a Professor in the Department of Biochemistry, Molecular Biology and Biophysics at UMN. Dr. Niedernhofer ’ s expertise is in DNA damage and repair, genome instability disorders, cellular senescence and aging. Her research program is centered on studying fundamental mechanisms of aging and developing therapeutics to target them. Her research program implements a murine model of a human progeroid syndrome...
Source: Videocast - All Events - October 4, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
Advancing Health Equity Through Culture-Centered Dietary Interventions to Address Chronic Diseases Virtual Workshop (Day 2)
Goals and Key Audience: Objectives: 1. Identify gaps and opportunities for research on the cultural adaptation of evidence-based dietary approaches (e.g., DASH and Mediterranean Diet) to address diet-related diseases in racial/ethnic populations; 2. Understand dietary acculturation and its influence on the development and effectiveness of dietary interventions among diverse immigrant populations; 3. Interrogate the influence of dietary acculturation on the gut microbiome, and understand gut microbiome response to traditional and evidence-based diets. Need and Justification: Adherence to evidence-based dietary approaches, s...
Source: Videocast - All Events - September 26, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
Advancing Health Equity Through Culture-Centered Dietary Interventions to Address Chronic Diseases Virtual Workshop (Day 1)
Goals and Key Audience: Objectives: 1. Identify gaps and opportunities for research on the cultural adaptation of evidence-based dietary approaches (e.g., DASH and Mediterranean Diet) to address diet-related diseases in racial/ethnic populations; 2. Understand dietary acculturation and its influence on the development and effectiveness of dietary interventions among diverse immigrant populations; 3. Interrogate the influence of dietary acculturation on the gut microbiome, and understand gut microbiome response to traditional and evidence-based diets. Need and Justification: Adherence to evidence-based dietary approaches, s...
Source: Videocast - All Events - September 26, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
Reducing cyber risks in the home environment
Taking care to address the challenges of securing remote patient monitoring devices will help mitigate the cybersecurity risks of hospital-at-home care, says Kevin Littlefield, principal, cybersecurity at MITRE. (Source: Healthcare ITNews Videos)
Source: Healthcare ITNews Videos - September 20, 2023 Category: Information Technology Source Type: video
Prospective Cohort Studies for Environmental Health Research
Established in 1968 in honor of the first NIH director of laboratories and clinics, the G. Burroughs Mider Lecture is presented by an NIH intramural scientist to recognize and appreciate outstanding contributions to biomedical research.Air date: 9/20/2023 2:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - September 7, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
Advancing Cardiovascular Health Equity Through Culture-Centered Dietary Interventions: Research Gaps and Opportunities (Day 2)
Adherence to evidence-based dietary approaches, such as the Dietary Approaches to Stop Hypertension (DASH) diet and Mediterranean diet, is associated with a multitude of health benefits, including lowered blood pressure, improved lipid profiles, reduced cardiovascular disease (CVD) incidence, and decreased risk of type 2 diabetes.1-5 Also, adherence to healthy dietary patterns is associated with decrease risk for several cancers and cancer mortality. 6, 7 Yet, the strength of these associations varies by race and ethnicity, though results have been inconsistent; and there are racial and ethnic differences in adherence to t...
Source: Videocast - All Events - August 30, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
Advancing Cardiovascular Health Equity Through Culture-Centered Dietary Interventions: Research Gaps and Opportunities
Goals and Key Audience:
Objectives:
1. Identify gaps and opportunities for research on the cultural adaptation of evidence-based dietary approaches (e.g., DASH and Mediterranean Diet) to address diet-related diseases in racial/ethnic populations;
2. Understand dietary acculturation and its influence on the development and effectiveness of dietary interventions among diverse immigrant populations;
3. Interrogate the influence of dietary acculturation on the gut microbiome, and understand gut microbiome response to traditional and evidence-based diets.
Need and Justification:
Adherence to evidence-based dietary approac...
Source: Videocast - All Events - August 23, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
The Social Genome in Nonhuman Primates
Jenny Tung, born 1982 in Seaford, Delaware, United States, studied Evolutionary Biology at Duke University, Durham, North Carolina, USA. She received her Ph.D. at Duke University investigating the causes and consequences of genetic variation in wild baboons, under the supervision of Susan Alberts and Gregory Wray. She spent her postdoctoral studies investigating the functional genomic signature of genotype and social environment in nonhuman primates, under the supervision of Yoav Gilad at the University of Chicago, Chicago, USA. In 2012, she joined the Department of Evolutionary Anthropology and the Duke Population Researc...
Source: Videocast - All Events - August 1, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
