Azithromycin-loaded liposomes and niosomes for the treatment of skin infections: Influence of excipients and preparative methods on the functional properties
Eur J Pharm Biopharm. 2024 Feb 20:114233. doi: 10.1016/j.ejpb.2024.114233. Online ahead of print.ABSTRACTThe aim of this study was to develop azithromycin (AZT)-loaded liposomes (LP) and niosomes (NS) useful for the treatment of bacterial skin infections and acne. LP based on phosphatidylcholine from egg yolk (EPC) or from soybean lecithin (SPC), and NS composed of sorbitan monopalmitate (Span 40) or sorbitan monostearate (Span 60) were prepared through the thin film hydration (TFH) and the ethanol injection (EI) methods. The formulations were subsequently characterized for their physico-chemical and functional properties....
Source: European Journal of Pharmaceutics and Biopharmaceutics - February 22, 2024 Category: Drugs & Pharmacology Authors: A Abruzzo R Pucci P M Abruzzo S Canaider C Parolin B Vitali F Valle M Brucale T Cerchiara B Luppi F Bigucci Source Type: research

Azithromycin-loaded liposomes and niosomes for the treatment of skin infections: Influence of excipients and preparative methods on the functional properties
Eur J Pharm Biopharm. 2024 Feb 20:114233. doi: 10.1016/j.ejpb.2024.114233. Online ahead of print.ABSTRACTThe aim of this study was to develop azithromycin (AZT)-loaded liposomes (LP) and niosomes (NS) useful for the treatment of bacterial skin infections and acne. LP based on phosphatidylcholine from egg yolk (EPC) or from soybean lecithin (SPC), and NS composed of sorbitan monopalmitate (Span 40) or sorbitan monostearate (Span 60) were prepared through the thin film hydration (TFH) and the ethanol injection (EI) methods. The formulations were subsequently characterized for their physico-chemical and functional properties....
Source: European Journal of Pharmaceutics and Biopharmaceutics - February 22, 2024 Category: Drugs & Pharmacology Authors: A Abruzzo R Pucci P M Abruzzo S Canaider C Parolin B Vitali F Valle M Brucale T Cerchiara B Luppi F Bigucci Source Type: research

Effects of different extenders, storage temperatures, and antioxidant supplementation on chilled semen quality: a review
AbstractThe successful preservation of ram semen is essential to promote genetic variability, ensure semen transportation, and inseminate multiple ewes. Currently, either animal or plant-based lipoprotein-based extenders are used for semen preservation. Animal product-based extenders include milk and egg yolk, while soybean lecithin is a plant-based extender. Although extenders containing products of animal origin better preserve the quality of chilled semen, the in vivo efficacy after 24  h of storage is still of great concern. Storage temperature is another important and effective factor in preserving sperm quality, whe...
Source: Tropical Animal Health and Production - February 22, 2024 Category: Veterinary Research Source Type: research

Modelling the low temperature growth boundaries of Salmonella Enteritidis in raw and pasteurized egg yolk, egg white and liquid whole egg: Influence of the initial concentration
Int J Food Microbiol. 2024 Feb 6;414:110619. doi: 10.1016/j.ijfoodmicro.2024.110619. Online ahead of print.ABSTRACTSalmonella is the most frequently reported cause of foodborne outbreaks with known origin in Europe, with eggs and egg products standing out as the most frequent food source (when it was known). The growth and survival of Salmonella in eggs and egg products have been extensively studied and, recently, it has been reported that factors such as the initial concentration and thermal history of the egg product can also influence its growth capability. Therefore, the objective of this study was to define the bounda...
Source: International Journal of Food Microbiology - February 17, 2024 Category: Food Science Authors: Silvia Guill én Lara Dom ínguez Pilar Ma ñas Ignacio Álvarez Elena Carrasco Guillermo Cebri án Source Type: research

Ultrasound-induced structural changes of different milk fat globule membrane protein-phospholipids complexes and their effects on physicochemical and functional properties of emulsions
This study investigated the effects of ultrasonic time (5 min, 10 min, 15 min) and power (150 W,300 W,500 W) on the structural properties of three types of phospholipids composed of different fatty acids (milk fat globule membrane phospholipid (MPL), egg yolk lecithin (EYL), soybean lecithin (SL)) and milk fat globule membrane protein (MFGMP). We found that the ultrasound treatment changed the conformation of the protein, and the emulsions prepared by the pretreatment showed better emulsification and stability, the lipid droplets were also more evenly distributed. Meanwhile, the flocculation phenomenon of the lipid droplet...
Source: Ultrasonics Sonochemistry - February 16, 2024 Category: Chemistry Authors: Yanjie Zhao Qian Ma Tao Zhou Lu Liu Yuxin Wang Xiaodong Li Xiuxiu Zhang Xiaoqing Dang Kouadio Jean Eric-Parfait Kouame Source Type: research

Ultrasound-induced structural changes of different milk fat globule membrane protein-phospholipids complexes and their effects on physicochemical and functional properties of emulsions
This study investigated the effects of ultrasonic time (5 min, 10 min, 15 min) and power (150 W,300 W,500 W) on the structural properties of three types of phospholipids composed of different fatty acids (milk fat globule membrane phospholipid (MPL), egg yolk lecithin (EYL), soybean lecithin (SL)) and milk fat globule membrane protein (MFGMP). We found that the ultrasound treatment changed the conformation of the protein, and the emulsions prepared by the pretreatment showed better emulsification and stability, the lipid droplets were also more evenly distributed. Meanwhile, the flocculation phenomenon of the lipid droplet...
Source: Ultrasonics Sonochemistry - February 16, 2024 Category: Chemistry Authors: Yanjie Zhao Qian Ma Tao Zhou Lu Liu Yuxin Wang Xiaodong Li Xiuxiu Zhang Xiaoqing Dang Kouadio Jean Eric-Parfait Kouame Source Type: research

Effects of taurine, cysteine and melatonin as antioxidant supplements to the freezing medium of Prochilodus brevis sperm
This study aimed to test taurine, cysteine, and melatonin on the freezing of Prochilodus brevis sperm and assess its effects on post-thawed sperm quality. Sperm was collected and seven pools were formed (n = 7). They were diluted (1:9) in standard medium (5% glucose, 10% dimethyl sulfoxide and 5% egg yolk) supplemented or not (control) with taurine (0.3, 1.0, 3.16 or 10.0 mM), cysteine (0.3, 1.0, 3.16 or 10.0 mM) or melatonin (0.6, 1.12, 2.0 or 3.56 mM). Post-thawed sperm was evaluated for kinetic (total motility, velocities, and percentage of rapid cells), morphology and membrane and DNA integrity. Differences were found ...
Source: Cryobiology - February 12, 2024 Category: Biology Authors: Thais Maia Torres Priscila Silva de Almeida-Monteiro Renata Vieira do Nascimento Silvio Alencar C ândido-Sobrinho Carla Tatiana Nascimento Sousa Yasmim Maia Ferreira Kamila Teixeira de Paula Carminda Sandra Brito Salmito-Vanderley Source Type: research

Production, characterization and therapeutic efficacy of egg yolk antibodies specific to < i > Nosema ceranae < /i >
by Mehmet Nuri A çık, Burcu Karagülle, Seda Yakut, Yasin Öztürk, Mehmet Ali Kutlu, Recep Kalın, Burhan ÇetinkayaNosema disease, caused byNosema ceranae, one of the single-celled fungal microsporidian parasites, is one of the most important and common diseases of adult honey bees. Since fumagillin, which has been used for decades in the control ofNosema disease in honey bees (Apis mellifera), poses a toxic threat and its efficacy againstN.ceranae is uncertain, there is an urgent need to develop alternative prophylactic and curative strategies for the treatment of this disease. The main aim of this study was to invest...
Source: PLoS One - February 9, 2024 Category: Biomedical Science Authors: Mehmet Nuri A çık Source Type: research

Metabolomics analysis of the yolk of Zhijin white goose during the embryogenesis based on LC-MS/MS
by Zhonglong Zhao, Hong Yang, Zhiwei Wang, Zhaobi Ai, Runqian Yang, Zhong Wang, Tiansong Wang, Kaibin Fu, Yong Zhang The egg yolk of the goose is rich in lipids, proteins and minerals, which is the main source of nutrition during the goose embryogenesis. Actually, the magnitude and variety of nutrients in yolk are dynamically changed to satisfy the nutritional requirements of different growth and development per iods. The yolk sac membrane (YSM) plays a role in metabolizing and absorbing nutrients from the yolk, which are then consumed by the embryo or extra-fetal tissues. Therefore, identification of metabolites in egg y...
Source: PLoS One - February 9, 2024 Category: Biomedical Science Authors: Zhonglong Zhao Source Type: research

Determination of the cryoprotective effect of n-methylacetamide in rabbit semen
CONCLUSION: DMSO appeared to be more useful for the cryopreservation of rabbit semen compared to MA. Doi.org/10.54680/fr23610110812.PMID:38311932 (Source: Cryo-Letters)
Source: Cryo-Letters - February 5, 2024 Category: Biology Authors: S A Akarsu I H Gungor T C Acisu A Cakir E Guler R H Koca I Yilmaz M Sonmez S Gur G Turk S O Kaya A Yuce Source Type: research

IGF-1 stabilizes goat sperm mitochondrial transmembrane potential and reduces dna fragmentation
CONCLUSION: IGF-1 may be used to improve post-thaw semen quality and fertility as measured by actual kidding rate. Doi.org/10.54680/fr23610110312.PMID:38311926 (Source: Cryo-Letters)
Source: Cryo-Letters - February 5, 2024 Category: Biology Authors: R Ranjan K Sharma M Kumar D K Swain S P Singh S D Kharche M K Singh M S Chauhan Source Type: research

Determination of the cryoprotective effect of n-methylacetamide in rabbit semen
CONCLUSION: DMSO appeared to be more useful for the cryopreservation of rabbit semen compared to MA. Doi.org/10.54680/fr23610110812.PMID:38311932 (Source: Cryo-Letters)
Source: Cryo-Letters - February 5, 2024 Category: Biology Authors: S A Akarsu I H Gungor T C Acisu A Cakir E Guler R H Koca I Yilmaz M Sonmez S Gur G Turk S O Kaya A Yuce Source Type: research

IGF-1 stabilizes goat sperm mitochondrial transmembrane potential and reduces dna fragmentation
CONCLUSION: IGF-1 may be used to improve post-thaw semen quality and fertility as measured by actual kidding rate. Doi.org/10.54680/fr23610110312.PMID:38311926 (Source: Cryo-Letters)
Source: Cryo-Letters - February 5, 2024 Category: Biology Authors: R Ranjan K Sharma M Kumar D K Swain S P Singh S D Kharche M K Singh M S Chauhan Source Type: research

Determination of the cryoprotective effect of n-methylacetamide in rabbit semen
CONCLUSION: DMSO appeared to be more useful for the cryopreservation of rabbit semen compared to MA. Doi.org/10.54680/fr23610110812.PMID:38311932 (Source: Cryo-Letters)
Source: Cryo-Letters - February 5, 2024 Category: Biology Authors: S A Akarsu I H Gungor T C Acisu A Cakir E Guler R H Koca I Yilmaz M Sonmez S Gur G Turk S O Kaya A Yuce Source Type: research

IGF-1 stabilizes goat sperm mitochondrial transmembrane potential and reduces dna fragmentation
CONCLUSION: IGF-1 may be used to improve post-thaw semen quality and fertility as measured by actual kidding rate. Doi.org/10.54680/fr23610110312.PMID:38311926 (Source: Cryo-Letters)
Source: Cryo-Letters - February 5, 2024 Category: Biology Authors: R Ranjan K Sharma M Kumar D K Swain S P Singh S D Kharche M K Singh M S Chauhan Source Type: research