How did all those calcium entered my father ’ s coronary artery doctor ?
“It was severe double vessel disease & turned out to be a complex angioplasty in LAD ”
Why doctor? what happened?
It was a hard lesion, there was plenty of calcium deposits. It was not clearly visible in the angiogram. I had to do IVUS. Curiously, the calcium was clustered in all the three planes of the vessel ( intima the media and adventitia) and they projected into the lumen blocking the path.
Image collage representation purpose
Thank you, doctor, how did you manage to remove it,?
It was a real struggle. I had to break the calcium shell before deploying the stent. (What we refer to as...
Source: Dr.S.Venkatesan MD - September 3, 2021 Category: Cardiology Authors: dr s venkatesan Tags: Cardiology -unresolved questions calcium supplementation coronary calcification intimal medial adventitial calcium ivl wolverine angiosculpt opn balloon orbitel atherectomy osteoporosis plaque calcium rotoablator serum calcium vs coron Source Type: blogs
Fight Aging! Newsletter, June 14th 2021
In conclusion, a number of high-income countries, changes in health expectancies over time have not kept pace with the growth in life expectancy. That is, people are living longer but disability and poor health are occupying an increasing proportion of later life. Our findings suggest that countries still need to make significant progress to achieve the WHO's Decade of Healthy Ageing goal of healthier, longer lives for all.
Progress on Understanding Why Human Growth Hormone Receptor Variants are Associated with Greater Longevity
https://www.fightaging.org/archives/2021/06/progress-on-understanding-why-human-gr...
Source: Fight Aging! - June 13, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Assessing Sarcopenia and Dynapenia via Ultrasound
Researchers here propose an approach to measure the progression of sarcopenia, the loss of muscle mass and strength with aging, via ultrasound assessment of muscle structure. The present most widely practiced approaches involve assessment of muscle mass, grip strength, walking speed, ability to stand up from a chair, and the like. As understanding of the underlying mechanisms of the condition grow, a more rigorous form of assessment becomes desirable, one that can hopefully be extended into detecting the earliest stages of sarcopenia, with an eye towards prevention.
While the definition of sarcopenia is an evolvin...
Source: Fight Aging! - June 10, 2021 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Fight Aging! Newsletter, January 27th 2020
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter,
please visit:
https://www.fightaging.org/newsletter/
Longevity Industry Consulting Services
Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - January 26, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Notes on the SENS Research Foundation Pitch Day, January 2020
The J.P. Morgan Healthcare conference runs every year in San Francisco, a big draw for the biotech industry, and many organizations take the opportunity to host events at the same time. Among these, the SENS Research Foundation has for the past few years hosted a pitch day in which biotech companies in the longevity industry, largely startups, present to that portion of the Bay Area investor community interested in funding the treatment of aging as a medical condition. I was there to present on progress at Repair Biotechnologies, and took some notes on the other companies as they talked about their work.
Kimera Labs
...
Source: Fight Aging! - January 20, 2020 Category: Research Authors: Reason Tags: Investment Source Type: blogs
Fight Aging! Newsletter, September 9th 2019
We examined human lung tissue from COPD patients and normal control subjects, and found a substantial increase in p16-expressing alveolar cells in COPD patients. Using a transgenic mouse deficient for p16, we demonstrated that lungs of mice lacking p16 were structurally and functionally resistant to CS-induced emphysema due to activation of IGF1/Akt regenerative and protective signaling.
Fat Tissue Surrounds Skeletal Muscle to Accelerate Atrophy in Aging and Obesity
https://www.fightaging.org/archives/2019/09/fat-tissue-surrounds-skeletal-muscle-to-accelerate-atrophy-in-aging-and-obesity/
Researchers he...
Source: Fight Aging! - September 8, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Declines in Limb Muscle Mass Correlate with Higher Mortality in Late Life
Given that resistance training is shown to reduce mortality in older individuals, it makes sense that we would see the opposite effect when looking at low muscle mass in limbs. Skeletal muscle isn't an inert tissue, being quite involved in insulin metabolism, for example, and exercise has all sorts of interesting effects on the operation of metabolism, such as upregulation of beneficial cellular stress response mechanisms. Aging is associated with a progressive loss of muscle mass and strength, with the loss of stem cell activity being a leading cause. This ultimately results in frailty and the condition of weakness known ...
Source: Fight Aging! - September 2, 2019 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
MKSAP: 55-year-old woman with an eating disorder
Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians.
A 55-year-old woman is evaluated for a new-patient visit. Medical history is significant for an eating disorder. Although she has maintained a normal weight for the past 20 years, she notes that prior to that time her weight would fluctuate in a range correlating with BMIs of 17 to 19. She has otherwise been healthy and currently feels well. She is postmenopausal and a never-smoker. Family history is significant for postmenopausal osteoporosis in her mother. Her medications are over-the-counter calcium and vitam...
Source: Kevin, M.D. - Medical Weblog - July 23, 2018 Category: General Medicine Authors: < a href="https://www.kevinmd.com/blog/post-author/mksap" rel="tag" > mksap < /a > Tags: Conditions Endocrinology Source Type: blogs
Fat Distribution Predicts a Person ’s Risk for Heart Attack
Obesity and overweight can lead to a heart attack, stroke, or diabetes. Yet, there are other ways to determine someone ’s chances of developing a cardiometabolic health condition. According to a recentstudy presented at the Radiological Society of North America annual meeting, the way fat is distributed throughout the body can indicate someone ’s cardiometabolic risk. Study lead Miriam A. Bredella, MD, a radiologist at Massachusetts General Hospital and associate professor at Harvard Medical School, and her colleagues evaluated 200 overweight and obese people who were the mean age of 37 and had similar BMI. The group o...
Source: radRounds - December 15, 2017 Category: Radiology Authors: Julie Morse Source Type: blogs
Professionalism And Choosing Wisely
The US health care system is plagued by the use of services that provide little clinical benefit. Estimates of expenditures on overuse of medical services range from 10–30 percent of total health care spending. These estimates are typically based on analyses of the geographic variation in patterns of care. For example, researchers at the Dartmouth Institute focused on differences in care use between high-spending and low-spending regions with no corresponding reductions in quality or outcomes. An analysis by the Network for Excellence in Health Innovation (formerly known as the New England Healthcare Institute) ident...
Source: Health Affairs Blog - October 24, 2017 Category: Health Management Authors: Michael Chernew and Daniel Wolfson Tags: Costs and Spending Quality Choosing Wisely inefficiency overuse of medical services Source Type: blogs
Exercise: Can a few minutes a day keep a hip fracture away?
This study is so important because it really gives all of us such a reasonable goal. Can we give it our strongest effort for one to two minutes a day? I think we can. It also shows that if we make a small, measurable, but regular change, we can all dance, run, jog, jump, or hop our way to better health!
The post Exercise: Can a few minutes a day keep a hip fracture away? appeared first on Harvard Health Blog. (Source: Harvard Health Blog)
Source: Harvard Health Blog - October 12, 2017 Category: Consumer Health News Authors: Nandini Mani, MD Tags: Exercise and Fitness Health Osteoporosis bone health brittle bones Source Type: blogs
Lions and Sentinel Nodes! Oh My!
Eid Mubarak!It seems surreal that two weeks have passed so quickly. As today is the holiday of Eid Al-Adha, the hospital has very little activity, and I ' m taking the day to pack, catch up on correspondence, and perhaps pay one last visit to Slipway for lunch.This was on Page 16 of the local English-language newspaper a few days ago. A coincidence with my arrival in country? I wonder...I haven ' t posted since heading out to Ngorongoro Crater, so let me briefly fill you in on that incredible experience. I ' ll place some photos here, but they can all be found at THIS LINK for your leisurely perusal. I left ...
Source: Dalai's PACS Blog - September 1, 2017 Category: Radiology Source Type: blogs
Zebra and Teleradiology Solutions Are Joining Forces
Zebra Medical Vision is partnering with India-based Teleradiology Solutions (TRS) to deliver its deep learning-powered image analysis system to 150 hospitals in 20 countries throughout Asia and Africa.Since 2015, Zebra has been working with health care facilities in the U.S. and Europe to bring technology that detects bone, liver, lung, and cardiovascular diseases. Their mission is to revolutionize the medical imaging service industry so that it can keep up with the needs of the steadily increasing middle class and aging populations. Their collaboration with TRS is a move to “bridge the growing gap between demand and sup...
Source: radRounds - July 14, 2017 Category: Radiology Authors: Julie Morse Source Type: blogs
Fight Aging! Newsletter, April 10th 2017
This study shows that lifespan-extending conditions can slow molecular changes associated with an epigenetic clock in mice livers.
Diverse interventions that extend mouse lifespan suppress shared age-associated epigenetic changes at critical gene regulatory regions
Age-associated epigenetic changes are implicated in aging. Notably, age-associated DNA methylation changes comprise a so-called aging "clock", a robust biomarker of aging. However, while genetic, dietary and drug interventions can extend lifespan, their impact on the epigenome is uncharacterised. To fill this knowledge gap, we defined age-assoc...
Source: Fight Aging! - April 9, 2017 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
The Mechanics of Kidney Aging
As examinations of aging go, this open access overview of kidney decline and kidney disease is more focused on the mechanics of the problem than most, which makes it an interesting read. As a bonus, it opens by touching on the thorny topic of whether aging is a disease, and where the arbitrary boundary lies between aging and disease. Kidney disease is not as large a problem in our species as heart disease and cancer, but that is only because most people are killed by something else first. Age-related fibrosis eats away at kidney tissue until there is no longer enough left fully functional to do its job. It is an unpleasant...
Source: Fight Aging! - April 3, 2017 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
