Fight Aging! Newsletter, July 4th 2022
This study showed that centenarians had very specific changes in CD4+ T cell populations, which were manifested by an elevated Th17/Treg ratio in vivo, as well as a changed secretory phenotype. Although the T cells of centenarians cannot resist the aging-related expression of proinflammatory genes, their secretory phenotype was altered, explaining the relatively low level of inflammation in centenarians. These results suggested the presence of a mechanism to ameliorate inflammaging in centenarians. This may be achieved by reversing the imbalance of Th17/Treg cells and reducing pro-inflammatory cytokines.
Longevit...
Source: Fight Aging! - July 3, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Longevity Conferences Coming up in Late 2022
Conferences are a measure of the health of a field; typically the more conferences one sees, the broader the efforts and the larger the funding. Most of the best conferences relating to aging research, and the longevity industry that has emerged from that research, feature an even mix of entrepreneurs, scientists, and investors. The networking at these conferences leads to the foundation of new ventures and seed funding for young ventures. This is important in a field in which there are many, many opportunities to make progress. Networking makes the world turn; it is an essential part of the messy, human process of bringin...
Source: Fight Aging! - June 30, 2022 Category: Research Authors: Reason Tags: Longevity Industry Source Type: blogs
Say it again:
This study in the Proceedings of the National Academy of Sciences finds that, in the context of the Covid 19 pandemic, " a single-payer universal healthcare system would have saved 212,000 lives in 2020 alone. We also calculated that US$105.6 billion of medical expenses associated with COVID-19 hospitalization could have been averted by a Medicare for All system. " This is not exactly news. Health services researchers have been making these sorts of calculations for decades, for as long as I ' ve even been on the periphery of the business, and it always comes out the same. With a universal single payer system we can:I...
Source: Stayin' Alive - June 14, 2022 Category: American Health Source Type: blogs
Fight Aging! Newsletter, June 13th 2022
In conclusion, long-term cumulative BP was associated with subsequent cognitive decline, dementia risk, and all-cause mortality in cognitively healthy adults aged ≥50 years. Efforts are required to control long-term systolic BP and pulse pressure and to maintain adequate diastolic BP.
Longer-Lived Mammals Tend to Have Lower Expression of Inflammation-Related Genes
https://www.fightaging.org/archives/2022/06/longer-lived-mammals-tend-to-have-lower-expression-of-inflammation-related-genes/
Researchers here make a few interesting observations on gene expression data from a range of mammalian species with...
Source: Fight Aging! - June 12, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Cancer Correlates with Increased Risk of Later Onset of Type 2 Diabetes
Researchers here note a correlation between cancer diagnosis and greater risk of later onset of type 2 diabetes. A reasonable guess is that this is mediated by the increased burden of cellular senescence produced by chemotherapy and radiotherapy, though, as the researchers point out, the widely different risks by cancer type may indicate that tumors are metabolically active in ways that specifically promote the metabolic dysfunction that leads to type 2 diabetes.
For patients with cancer, prevalent type 2 diabetes at the date of cancer diagnosis is associated with increased cancer-specific and all-cause mortality....
Source: Fight Aging! - June 9, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Study on the “ABCs of Mental Health” finds that simply believing you can improve mental wellbeing helps actually improve it
This article was originally published on The Conversation.
To Learn More:
Impact evaluation of the “ABCs of Mental Health” in Denmark and the role of mental health-promoting beliefs and actions (opens paper on Mental Health and Social Inclusion journal)
Study: Higher mental wellbeing (in 2016) seen to lower healthcare costs (in 2017)
The post Study on the “ABCs of Mental Health” finds that simply believing you can improve mental wellbeing helps actually improve it appeared first on SharpBrains. (Source: SharpBrains)
Source: SharpBrains - May 12, 2022 Category: Neuroscience Authors: The Conversation Tags: Brain/ Mental Health Education & Lifelong Learning mental wellbeing mental-disorders mental-health-treatment mind Source Type: blogs
68 Mind Your Business Quotes to Help Simplify Your Life
It’s sometimes too easy to get stuck in thinking about what other people may think or say if you do what you deep down want to do.
So you hold back. Get stuck in inaction.
To help you with that I’d like to share the 68 most helpful mind your own business quotes.
To get you unstuck and also to help you handle negative comments or busybodies interfering in your life in a way you don’t want or need.
I hope you’ll find something useful and freeing in this post.
And if you want even more inspiration to help you mind your own business and focus on what you want then check out this post with quotes on knowing your own wo...
Source: Practical Happiness and Awesomeness Advice That Works | The Positivity Blog - May 10, 2022 Category: Consumer Health News Authors: Henrik Edberg Tags: Inspirational Quotes Personal Development Source Type: blogs
Fight Aging! Newsletter, April 25th 2022
We examined central genetic and environmental lifespan regulators (putative anti-aging interventions, PAAIs; the following PAAIs were examined: mTOR loss-of-function, loss-of-function in growth hormone signaling, dietary restriction) for a possible countering of the signs and symptoms of aging. Importantly, in our study design, we included young treated groups of animals, subjected to PAAIs prior to the onset of detectable age-dependent phenotypic change. In parallel to our studies in mice, we assessed genetic variants for their effects on age-sensitive phenotypes in humans.
We observed that, surprisingly, many PAAI...
Source: Fight Aging! - April 24, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Evidence Supporting the View that Familial Longevity is Largely Cultural
Researchers have spent a great deal of effort looking for genetic determinants of longevity in long-lived families. Elsewhere, initiatives searching large national databases for genetic determinants of longevity have turned up increasing evidence for genetic variations to play very little role in human life span. The pendulum is swinging towards the idea that the specifics of culture within human lineages are largely responsible for differences in longevity: who stays thin; who exercises; who maintains beneficial dietary habits; who has a lesser early life exposure to persistent pathogens; and so forth.
What makes...
Source: Fight Aging! - April 18, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Denmark Finds New Ways to Promote Underground Trade
Jeffrey A. SingerIn 1969, Denmark became thefirst country to legalize pictorial and audiovisual pornography, so it is acutely painful to see its government take a new puritanical turn.The Health Ministry has already set the goal of raising the alcohol drinking age from 16 to 18. And last month, Denmark ’s health minister announcedplans to ban the sale of tobacco and nicotine products to anyone born after 2010. This way, the Health Ministry hopes to gradually phase out the use of all tobacco and nicotine products in the country. The Health Ministry took this action to address the 13,600 annual deaths from smoking ‐...
Source: Cato-at-liberty - April 11, 2022 Category: American Health Authors: Jeffrey A. Singer Source Type: blogs
What's new in midwifery - research - 11th April 2022
COVIDAssociation of COVID-19 vaccination in pregnancy with adverse peripartum outcomes, study carried out in Canada looking at primarily mRNA vaccines given in second and third trimester, comparing with vaccination given after pregnancy or no vaccination given, found no significant association.Retrospective cohort study of association of SARS-CoV-2 vaccination during pregnancy with pregnancy outcomes, " In this population-based retrospective cohort study that included 157 521 deliveries in Sweden and Norway, SARS-CoV-2 vaccination during pregnancy, compared with no SARS-CoV-2 vaccination during pregnancy, was no...
Source: Browsing - April 11, 2022 Category: Databases & Libraries Tags: midwifery Source Type: blogs
From Surgeries To Keeping Company: The Place Of Robots In Healthcare
Assisting surgeries, disinfecting rooms, dispensing medication, keeping company: believe it or not these are the tasks medical robots will soon undertake in hospitals, pharmacies, or your nearest doctor’s office. These new ‘colleagues’ will definitely make a difference in every field of medicine. Here’s our overview to understand robotics in healthcare better so that everyone can prepare for the appearance of mechanic helpers in medical facilities.
Metallic allies for the benefit of the vulnerable
While there are concerns for machines replacing people in the workforce, we believe there are adv...
Source: The Medical Futurist - April 11, 2022 Category: Information Technology Authors: berci.mesko Tags: Future of Medicine Future of Pharma Robotics digital health Healthcare Hospital medical nanotechnology Surgery pharmacies future of hospital blood telemedicine social companion social companion robot telemedical medical rob Source Type: blogs
What's new in midwifery - research - 30th March 2022
And some research, lots of it from theMcMaster Evidence Alerts, which flag up things practitioners have identified as being useful or important.I think librarian intervention (or a subscription or payment) will be needed for all these except where I have indicated they are open access.First, aRCT from Denmark to investigate if the rebozo intervention (a birthing shawl) performed by the pregnant woman and her partner before external cephalic version increases the rate of cephalic presentations at birth.Then, areport of the Oneplus trial in Sweden, looking at whether having two midwives present in the second stage of labour ...
Source: Browsing - March 30, 2022 Category: Databases & Libraries Tags: midwifery Source Type: blogs
My Recent Podcast on " The Diabetes Way "
A frequent complaint about U.S. prescription drug prices is it is difficult to explain WHY the prices here are so high. A frequent pharma answer to the question WHY is this happening is " it ' s complicated " . They aren ' t kidding. it IS complicated. But today, there are tools on the internet which can help many people navigate the dysfunctional U.S. system without being taken to the cleaners. I recently did a podcast about that which might be worth listening to. But it ' s helpful to understand how I became the guy the podcasters wanted to interview about the subject.Back in September 2021, I was invited as a guest to s...
Source: Scott's Web Log - March 23, 2022 Category: Endocrinology Tags: David Kliff 2022 Amber Clour coupons podcast prescriptions rebates Rx The Diabetes Way Source Type: blogs
