Is methylphenidate an effective treatment for children and adolescents with attention deficit hyperactivity disorder (ADHD) and does it cause unwanted effects?
The Cochrane Developmental, Psychosocial and Learning Problems Group produced several reviews relevant to the treatment of attention deficit hyperactivity disorder and the update for one of these, investigating the drug methylphenidate, was published in March 2023. Here ' s one of the authors, Maja Storm from the Psychiatric Research Unit, Region Zealand in Denmark, to tell us about the latest evidence. (Source: Podcasts from The Cochrane Library)
Source: Podcasts from The Cochrane Library - October 23, 2023 Category: General Medicine Authors: Cochrane Source Type: podcasts

An anti-CRISPR system that helps save viruses from destruction
In this episode:00:47 An RNA-based viral system that mimics bacterial immune defencesTo protect themselves against viral infection, bacteria often use CRISPR-Cas systems to identify and destroy an invading virus’s genetic material. But viruses aren’t helpless and can deploy countermeasures, known as anti-CRISPRs, to neutralise host defences. This week, a team describe a new kind of anti-CRISPR system, based on RNA, which protects viruses by mimicking part of the CRISPR-Cas system. The researchers hope that this discovery could have future biotechnology applications, including making CRISPR-Cas genome editing more preci...
Source: Nature Podcast - October 18, 2023 Category: Science Authors: Springer Nature Limited Source Type: podcasts

Is Remote Ischemic Conditioning (RIC) an Effective Treatment for Acute Stroke?
It’s been unclear whether remote ischemic conditioning (RIC) with transient cycles of limb ischemia and reperfusion is an effective treatment for acute stroke. JAMA Deputy Editor Chris Muth, MD, speaks with author Rolf Blauenfeldt, MD, Aarhus University Hospital, Denmark, about the RESIST randomized clinical trial, which looks at the effect of RIC when initiated in the prehospital setting. Related Content: Remote Ischemic Conditioning for Acute Stroke (Source: JAMA Author Interviews)
Source: JAMA Author Interviews - October 3, 2023 Category: General Medicine Authors: JAMA Network Source Type: podcasts

Why cats love tuna, and powering robots with tiny explosions
Receptors that give our feline friends a craving for meat, and using combustion to propel insect-size robots   First up on this week’s episode, Online News Editor David Grimm joins host Sarah Crespi to talk about why despite originating from a dry, desert environment cats seem to love to eat fish.   Next on the show, bugs such as ants are tiny while at the same time fast and strong, and small robots can’t seem to match these insectile feats of speed and power. Cameron Aubin, a postdoc at Cornell University who will shortly join the University of Michigan, discusses using miniscule combustion reactions to bring sm...
Source: Science Magazine Podcast - September 14, 2023 Category: Science Authors: Science Magazine Source Type: podcasts

Why cats love tuna, and powering robots with tiny explosions
Receptors that give our feline friends a craving for meat, and using combustion to propel insect-size robots   First up on this week’s episode, Online News Editor David Grimm joins host Sarah Crespi to talk about why despite originating from a dry, desert environment cats seem to love to eat fish.   Next on the show, bugs such as ants are tiny while at the same time fast and strong, and small robots can’t seem to match these insectile feats of speed and power. Cameron Aubin, a postdoc at Cornell University who will shortly join the University of Michigan, discusses using miniscule combustion reactions to bring sm...
Source: Science Magazine Podcast - September 14, 2023 Category: Science Authors: Science Magazine Source Type: podcasts

What killed off North American megafauna, and making languages less complicated
Ancient wildfires may have doomed Southern California’s big mammals, and do insular societies have more complex languages?   First up on this week’s show, what killed off North America’s megafauna, such as dire wolves and saber-toothed cats? Online News Editor Mike Price joins host Sarah Crespi to talk about the likely culprits: climate or humans, or one that combines both—fire. They discuss how the La Brea Tar Pits are helping researchers figure this out. Read the related Science paper.   Next up, do languages get less complex when spoken in multilingual societies? Olena Shcherbakova, a doctoral researcher a...
Source: Science Magazine Podcast - August 17, 2023 Category: Science Authors: Science Magazine Source Type: podcasts

What killed off North American megafauna, and making languages less complicated
Ancient wildfires may have doomed Southern California’s big mammals, and do insular societies have more complex languages?   First up on this week’s show, what killed off North America’s megafauna, such as dire wolves and saber-toothed cats? Online News Editor Mike Price joins host Sarah Crespi to talk about the likely culprits: climate or humans, or one that combines both—fire. They discuss how the La Brea Tar Pits are helping researchers figure this out. Read the related Science paper.   Next up, do languages get less complex when spoken in multilingual societies? Olena Shcherbakova, a doctoral researcher a...
Source: Science Magazine Podcast - August 17, 2023 Category: Science Authors: Science Magazine Source Type: podcasts

TWiV 1012: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses the potential for recurrent Mpox outbreaks among gay, bisexual, and other men who have sex with men, association between SARS-CoV-2 variants and frequency of acute symptoms, prospective study of key correlates for household transmission of SARS-CoV-2, Pfizer’s PAXLOVID™ receiving FDA approval for adult patients at high risk of progression to severe COVID-19, efficacy and safety of antimicrobial stewardship prospective audit and feedback in patients hospitalized with COVID-19, development of a definition of postacute sequelae of SARS-CoV-2 infection, COVID-19 and risk...
Source: This Week in Virology - MP3 Edition - June 3, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Talking tongues, detecting beer, and shifting perspectives on females
Why it’s so hard to understand the tongue, a book on a revolutionary shift toward studying the female of the species, and using proteomics to find beer in a painting   First on the show this week, Staff Writer Elizabeth Pennisi joins host Sarah Crespi to talk tongues: Who has them, who doesn’t, and all their amazing elaborations.   We also have the first in a new six-part series on books exploring the science of sex and gender. For this month’s installment, host Angela Saini talks with evolutionary biologist Malin Ah-King about her book The Female Turn: How Evolutionary Science Shifted Perceptions About Females...
Source: Science Magazine Podcast - May 25, 2023 Category: Science Authors: Science Magazine Source Type: podcasts

Talking tongues, detecting beer, and shifting perspectives on females
Why it’s so hard to understand the tongue, a book on a revolutionary shift toward studying the female of the species, and using proteomics to find beer in a painting   First on the show this week, Staff Writer Elizabeth Pennisi joins host Sarah Crespi to talk tongues: Who has them, who doesn’t, and all their amazing elaborations.   We also have the first in a new six-part series on books exploring the science of sex and gender. For this month’s installment, host Angela Saini talks with evolutionary biologist Malin Ah-King about her book The Female Turn: How Evolutionary Science Shifted Perceptions About Females...
Source: Science Magazine Podcast - May 25, 2023 Category: Science Authors: Science Magazine Source Type: podcasts

Can tests for inflammation help doctors decide whether to use antibiotics for airway infections?
Acute respiratory infections are one of the most common reasons for people to present to primary care and decisions about whether or not to prescribe antibiotics might rely on point-of-care tests for inflammation. The relevant Cochrane review was updated in October 2022 and we asked new lead author, Siri Aas Smedemark from Odense University Hospital in Denmark, to tell us more in this podcast. (Source: Podcasts from The Cochrane Library)
Source: Podcasts from The Cochrane Library - May 22, 2023 Category: General Medicine Authors: Cochrane Source Type: podcasts

TWiV 1004: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses the U.S. Food and Drug Administration approving Arexvy: the first respiratory syncytial virus (RSV) vaccine approved for use in the United State, association between SARS-CoV-2 and metagenomic content of samples from the Huanan Seafood Market, researchers disagree over how bad it is to be reinfected and whether COVID-19 can cause lasting changes to the immune system, virtual care and emergency department use during the COVID-19 pandemic among patients of family physicians in Canada, vaccination with BCG-Denmark did not result in a lower risk of COVID-19 among healt...
Source: This Week in Virology - MP3 Edition - May 6, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

What are the benefits and risks of medication reviews for hospitalised adults?
Several strategies are used to monitor and optimise the use of drugs for hospitalised patients and the Cochrane review of medication review was updated in January 2023. In this podcast, one of the group ’s researchers, Mikkel Christensen, talks with lead author Cille Bülow, both from Copenhagen University Hospital in Denmark, about their latest findings. (Source: Podcasts from The Cochrane Library)
Source: Podcasts from The Cochrane Library - March 6, 2023 Category: General Medicine Authors: Cochrane Source Type: podcasts

Battling bias in medicine, and how dolphins use vocal fry
On this week’s show: Researchers are finding new ways to mitigate implicit bias in medical settings, and how toothed whales use distinct vocal registers for echolocation and communication First up this week: how to fight unconscious bias in the clinic. Staff Writer Rodrigo Pérez Ortega talks with host Sarah Crespi about how researchers are attempting to fight bias on many fronts—from online classes to machine learning to finding a biomarker for pain. Next up on the show: a close look at toothed whale vocalization. Though we have known for more than 50 years that toothed whales such as orcas, sperm whales, and dolphi...
Source: Science Magazine Podcast - March 2, 2023 Category: Science Authors: Science Magazine Source Type: podcasts

Battling bias in medicine, and how dolphins use vocal fry
On this week’s show: Researchers are finding new ways to mitigate implicit bias in medical settings, and how toothed whales use distinct vocal registers for echolocation and communication First up this week: how to fight unconscious bias in the clinic. Staff Writer Rodrigo Pérez Ortega talks with host Sarah Crespi about how researchers are attempting to fight bias on many fronts—from online classes to machine learning to finding a biomarker for pain. Next up on the show: a close look at toothed whale vocalization. Though we have known for more than 50 years that toothed whales such as orcas, sperm whales, and dolphi...
Source: Science Magazine Podcast - March 2, 2023 Category: Science Authors: Science Magazine Source Type: podcasts