Daily intake of 30 mg duloxetine is effective in decreasing premature ejaculation severity: a prospective randomized placebo-controlled cross over clinical trial
ConclusionDuloxetine is an effective drug for treatment of LPE and APE patients. Further, larger studies are needed to compare duloxetine to different known therapeutic modalities for PE to assert it ’s efficacy and superiority. (Source: Basic and Clinical Andrology)
Source: Basic and Clinical Andrology - December 5, 2023 Category: Urology & Nephrology Source Type: research

A multicomponent physical activity home-based intervention for fibromyalgia patients: effects on clinical and skin biopsy features
CONCLUSIONS: Physical activity could improve FM outcomes, with a possible beneficial impact on peripheral factors contributing to pain-related disability.PMID:38019150 | DOI:10.55563/clinexprheumatol/iukp4c (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - November 29, 2023 Category: Rheumatology Authors: Eleonora Gentile Silvia Giovanna Quitadamo Livio Clemente Valerio Bonavolont à Raffaella Lombardi Giuseppe Lauria Gianpiero Greco Francesco Fischetti Marina De Tommaso Source Type: research

PROCESS trial: Effect of duloxetine premedication for postherpetic neuralgia within 72  h of herpes zoster reactivation: a randomized controlled trial
CONCLUSION: Although absolute prevention for PHN does not occur, this trial found that premedication with duloxetine can reduce pain associated with HZ, and therefore have clinically relevant benefits.TRIAL REGISTRATION: Clinicaltrials.gov NCT04313335. Registered on 18 March 2020.PMID:38015658 | DOI:10.1093/cid/ciad714 (Source: Herpes)
Source: Herpes - November 28, 2023 Category: Infectious Diseases Authors: Chunmei Zhao Tingjie Zhang Qian Zhu Zheng Chen Hao Ren Niti Shrestha Lan Meng Ying Shen Fang Luo Source Type: research

PROCESS trial: Effect of duloxetine premedication for postherpetic neuralgia within 72  h of herpes zoster reactivation: a randomized controlled trial
CONCLUSION: Although absolute prevention for PHN does not occur, this trial found that premedication with duloxetine can reduce pain associated with HZ, and therefore have clinically relevant benefits.TRIAL REGISTRATION: Clinicaltrials.gov NCT04313335. Registered on 18 March 2020.PMID:38015658 | DOI:10.1093/cid/ciad714 (Source: Herpes)
Source: Herpes - November 28, 2023 Category: Infectious Diseases Authors: Chunmei Zhao Tingjie Zhang Qian Zhu Zheng Chen Hao Ren Niti Shrestha Lan Meng Ying Shen Fang Luo Source Type: research

Venlafaxine aggravating interstitial pneumonia: A case report
Int J Clin Pharmacol Ther. 2023 Nov 16. doi: 10.5414/CP204459. Online ahead of print.ABSTRACTA 70-year-old male taking venlafaxine for depression developed interstitial pneumonia and was admitted with shortness of breath and dyspnea. A computed tomography (CT) chest scan showed diffuse multiple lung lesions in both lungs, suggesting interstitial changes with inflammation or exudation. Compared with the CT chest scan 1 month earlier, there were significant progresses and new findings. The clinical diagnosis was interstitial pneumonia with pulmonary infection. The patient had been treated with fluvoxamine 100 mg/day, duloxet...
Source: Clinical Pharmacology and Therapeutics - November 16, 2023 Category: Drugs & Pharmacology Authors: Xia Wu Lutao Zhang Chuanping Wang Source Type: research

Venlafaxine aggravating interstitial pneumonia: A case report
Int J Clin Pharmacol Ther. 2023 Nov 16. doi: 10.5414/CP204459. Online ahead of print.ABSTRACTA 70-year-old male taking venlafaxine for depression developed interstitial pneumonia and was admitted with shortness of breath and dyspnea. A computed tomography (CT) chest scan showed diffuse multiple lung lesions in both lungs, suggesting interstitial changes with inflammation or exudation. Compared with the CT chest scan 1 month earlier, there were significant progresses and new findings. The clinical diagnosis was interstitial pneumonia with pulmonary infection. The patient had been treated with fluvoxamine 100 mg/day, duloxet...
Source: International Journal of Clinical Pharmacology and Therapeutics - November 16, 2023 Category: Drugs & Pharmacology Authors: Xia Wu Lutao Zhang Chuanping Wang Source Type: research