Study Compares Clinical Outcomes of Older Adults Prescribed 10 Common Antidepressants
Older adults with depression may be least likely to discontinue or switch treatment when prescribed sertraline for the first time compared with other antidepressants, suggests areport inThe American Journal of Psychiatry. The study compared one-year outcomes in 93,000 Danish residents with depression who for the first time filled a prescription for one of 10 antidepressants. The research was funded in part by the Health Research Foundation of the Central Denmark Region.“Although clinical trials are considered the gold standard in drug effectiveness research, their experimental conditions often do not represent complex, r...
Source: Psychiatr News - October 23, 2023 Category: Psychiatry Tags: antidepressants cardiovascular problems death depression falls older adults sertraline The American Journal of Psychiatry treatment discontinuation Source Type: research
Real-World Evidence on Clinical Outcomes of Commonly Used Antidepressants in Older Adults Initiating Antidepressants for Depression: A Nationwide Cohort Study in Denmark
CONCLUSIONS: This real-world evidence suggests that clinical outcomes may vary among initiators of commonly used antidepressants in older adults, which may inform benefit-risk evaluation at treatment initiation, and highlights the importance of careful selection of antidepressant treatment.PMID:37849303 | DOI:10.1176/appi.ajp.20230356 (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - October 18, 2023 Category: Psychiatry Authors: Kazi Ishtiak-Ahmed Katherine L Musliner Kaj Sparle Christensen Erik Lykke Mortensen Andrew A Nierenberg Christiane Gasse Source Type: research
Clinical pharmacokinetics of nebivolol: a systematic review
Drug Metab Rev. 2023 Oct 17:1-13. doi: 10.1080/03602532.2023.2271195. Online ahead of print.ABSTRACTNebivolol is a beta-1 receptor blocker used to treat hypertension, heart failure, erectile dysfunction, vascular disease, and diabetes mellitus. This review investigated the data regarding pharmacokinetic (PK) parameters, drug-drug interactions, dextrorotatory (D), and levorotatory (L) stereoisomers of nebivolol. The articles related to the PK of nebivolol were retrieved by searching the five databases; Google Scholar, PubMed, Cochrane Library, ScienceDirect, and EBSCO. A total of 20 studies comprising plasma concentration-t...
Source: Drug Metabolism Reviews - October 18, 2023 Category: Drugs & Pharmacology Authors: Nida Hanif Ammara Zamir Imran Imran Hamid Saeed Abdul Majeed Anees Ur Rehman Waseem Ashraf Faleh Alqahtani Muhammad Fawad Rasool Source Type: research
Real-World Evidence on Clinical Outcomes of Commonly Used Antidepressants in Older Adults Initiating Antidepressants for Depression: A Nationwide Cohort Study in Denmark
CONCLUSIONS: This real-world evidence suggests that clinical outcomes may vary among initiators of commonly used antidepressants in older adults, which may inform benefit-risk evaluation at treatment initiation, and highlights the importance of careful selection of antidepressant treatment.PMID:37849303 | DOI:10.1176/appi.ajp.20230356 (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - October 18, 2023 Category: Psychiatry Authors: Kazi Ishtiak-Ahmed Katherine L Musliner Kaj Sparle Christensen Erik Lykke Mortensen Andrew A Nierenberg Christiane Gasse Source Type: research
Clinical pharmacokinetics of nebivolol: a systematic review
Drug Metab Rev. 2023 Oct 17:1-13. doi: 10.1080/03602532.2023.2271195. Online ahead of print.ABSTRACTNebivolol is a beta-1 receptor blocker used to treat hypertension, heart failure, erectile dysfunction, vascular disease, and diabetes mellitus. This review investigated the data regarding pharmacokinetic (PK) parameters, drug-drug interactions, dextrorotatory (D), and levorotatory (L) stereoisomers of nebivolol. The articles related to the PK of nebivolol were retrieved by searching the five databases; Google Scholar, PubMed, Cochrane Library, ScienceDirect, and EBSCO. A total of 20 studies comprising plasma concentration-t...
Source: Drug Metabolism Reviews - October 18, 2023 Category: Drugs & Pharmacology Authors: Nida Hanif Ammara Zamir Imran Imran Hamid Saeed Abdul Majeed Anees Ur Rehman Waseem Ashraf Faleh Alqahtani Muhammad Fawad Rasool Source Type: research
Real-World Evidence on Clinical Outcomes of Commonly Used Antidepressants in Older Adults Initiating Antidepressants for Depression: A Nationwide Cohort Study in Denmark
CONCLUSIONS: This real-world evidence suggests that clinical outcomes may vary among initiators of commonly used antidepressants in older adults, which may inform benefit-risk evaluation at treatment initiation, and highlights the importance of careful selection of antidepressant treatment.PMID:37849303 | DOI:10.1176/appi.ajp.20230356 (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - October 18, 2023 Category: Psychiatry Authors: Kazi Ishtiak-Ahmed Katherine L Musliner Kaj Sparle Christensen Erik Lykke Mortensen Andrew A Nierenberg Christiane Gasse Source Type: research
Clinical pharmacokinetics of nebivolol: a systematic review
Drug Metab Rev. 2023 Oct 17:1-13. doi: 10.1080/03602532.2023.2271195. Online ahead of print.ABSTRACTNebivolol is a beta-1 receptor blocker used to treat hypertension, heart failure, erectile dysfunction, vascular disease, and diabetes mellitus. This review investigated the data regarding pharmacokinetic (PK) parameters, drug-drug interactions, dextrorotatory (D), and levorotatory (L) stereoisomers of nebivolol. The articles related to the PK of nebivolol were retrieved by searching the five databases; Google Scholar, PubMed, Cochrane Library, ScienceDirect, and EBSCO. A total of 20 studies comprising plasma concentration-t...
Source: Drug Metabolism Reviews - October 18, 2023 Category: Drugs & Pharmacology Authors: Nida Hanif Ammara Zamir Imran Imran Hamid Saeed Abdul Majeed Anees Ur Rehman Waseem Ashraf Faleh Alqahtani Muhammad Fawad Rasool Source Type: research
Real-World Evidence on Clinical Outcomes of Commonly Used Antidepressants in Older Adults Initiating Antidepressants for Depression: A Nationwide Cohort Study in Denmark
CONCLUSIONS: This real-world evidence suggests that clinical outcomes may vary among initiators of commonly used antidepressants in older adults, which may inform benefit-risk evaluation at treatment initiation, and highlights the importance of careful selection of antidepressant treatment.PMID:37849303 | DOI:10.1176/appi.ajp.20230356 (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - October 18, 2023 Category: Psychiatry Authors: Kazi Ishtiak-Ahmed Katherine L Musliner Kaj Sparle Christensen Erik Lykke Mortensen Andrew A Nierenberg Christiane Gasse Source Type: research
Clinical pharmacokinetics of nebivolol: a systematic review
Drug Metab Rev. 2023 Oct 17:1-13. doi: 10.1080/03602532.2023.2271195. Online ahead of print.ABSTRACTNebivolol is a beta-1 receptor blocker used to treat hypertension, heart failure, erectile dysfunction, vascular disease, and diabetes mellitus. This review investigated the data regarding pharmacokinetic (PK) parameters, drug-drug interactions, dextrorotatory (D), and levorotatory (L) stereoisomers of nebivolol. The articles related to the PK of nebivolol were retrieved by searching the five databases; Google Scholar, PubMed, Cochrane Library, ScienceDirect, and EBSCO. A total of 20 studies comprising plasma concentration-t...
Source: Drug Metabolism Reviews - October 18, 2023 Category: Drugs & Pharmacology Authors: Nida Hanif Ammara Zamir Imran Imran Hamid Saeed Abdul Majeed Anees Ur Rehman Waseem Ashraf Faleh Alqahtani Muhammad Fawad Rasool Source Type: research
Real-World Evidence on Clinical Outcomes of Commonly Used Antidepressants in Older Adults Initiating Antidepressants for Depression: A Nationwide Cohort Study in Denmark
CONCLUSIONS: This real-world evidence suggests that clinical outcomes may vary among initiators of commonly used antidepressants in older adults, which may inform benefit-risk evaluation at treatment initiation, and highlights the importance of careful selection of antidepressant treatment.PMID:37849303 | DOI:10.1176/appi.ajp.20230356 (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - October 18, 2023 Category: Psychiatry Authors: Kazi Ishtiak-Ahmed Katherine L Musliner Kaj Sparle Christensen Erik Lykke Mortensen Andrew A Nierenberg Christiane Gasse Source Type: research
Clinical pharmacokinetics of nebivolol: a systematic review
Drug Metab Rev. 2023 Oct 17:1-13. doi: 10.1080/03602532.2023.2271195. Online ahead of print.ABSTRACTNebivolol is a beta-1 receptor blocker used to treat hypertension, heart failure, erectile dysfunction, vascular disease, and diabetes mellitus. This review investigated the data regarding pharmacokinetic (PK) parameters, drug-drug interactions, dextrorotatory (D), and levorotatory (L) stereoisomers of nebivolol. The articles related to the PK of nebivolol were retrieved by searching the five databases; Google Scholar, PubMed, Cochrane Library, ScienceDirect, and EBSCO. A total of 20 studies comprising plasma concentration-t...
Source: Drug Metabolism Reviews - October 18, 2023 Category: Drugs & Pharmacology Authors: Nida Hanif Ammara Zamir Imran Imran Hamid Saeed Abdul Majeed Anees Ur Rehman Waseem Ashraf Faleh Alqahtani Muhammad Fawad Rasool Source Type: research
Real-World Evidence on Clinical Outcomes of Commonly Used Antidepressants in Older Adults Initiating Antidepressants for Depression: A Nationwide Cohort Study in Denmark
CONCLUSIONS: This real-world evidence suggests that clinical outcomes may vary among initiators of commonly used antidepressants in older adults, which may inform benefit-risk evaluation at treatment initiation, and highlights the importance of careful selection of antidepressant treatment.PMID:37849303 | DOI:10.1176/appi.ajp.20230356 (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - October 18, 2023 Category: Psychiatry Authors: Kazi Ishtiak-Ahmed Katherine L Musliner Kaj Sparle Christensen Erik Lykke Mortensen Andrew A Nierenberg Christiane Gasse Source Type: research
Clinical pharmacokinetics of nebivolol: a systematic review
Drug Metab Rev. 2023 Oct 17:1-13. doi: 10.1080/03602532.2023.2271195. Online ahead of print.ABSTRACTNebivolol is a beta-1 receptor blocker used to treat hypertension, heart failure, erectile dysfunction, vascular disease, and diabetes mellitus. This review investigated the data regarding pharmacokinetic (PK) parameters, drug-drug interactions, dextrorotatory (D), and levorotatory (L) stereoisomers of nebivolol. The articles related to the PK of nebivolol were retrieved by searching the five databases; Google Scholar, PubMed, Cochrane Library, ScienceDirect, and EBSCO. A total of 20 studies comprising plasma concentration-t...
Source: Drug Metabolism Reviews - October 18, 2023 Category: Drugs & Pharmacology Authors: Nida Hanif Ammara Zamir Imran Imran Hamid Saeed Abdul Majeed Anees Ur Rehman Waseem Ashraf Faleh Alqahtani Muhammad Fawad Rasool Source Type: research
Real-World Evidence on Clinical Outcomes of Commonly Used Antidepressants in Older Adults Initiating Antidepressants for Depression: A Nationwide Cohort Study in Denmark
CONCLUSIONS: This real-world evidence suggests that clinical outcomes may vary among initiators of commonly used antidepressants in older adults, which may inform benefit-risk evaluation at treatment initiation, and highlights the importance of careful selection of antidepressant treatment.PMID:37849303 | DOI:10.1176/appi.ajp.20230356 (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - October 18, 2023 Category: Psychiatry Authors: Kazi Ishtiak-Ahmed Katherine L Musliner Kaj Sparle Christensen Erik Lykke Mortensen Andrew A Nierenberg Christiane Gasse Source Type: research
Clinical pharmacokinetics of nebivolol: a systematic review
Drug Metab Rev. 2023 Oct 17:1-13. doi: 10.1080/03602532.2023.2271195. Online ahead of print.ABSTRACTNebivolol is a beta-1 receptor blocker used to treat hypertension, heart failure, erectile dysfunction, vascular disease, and diabetes mellitus. This review investigated the data regarding pharmacokinetic (PK) parameters, drug-drug interactions, dextrorotatory (D), and levorotatory (L) stereoisomers of nebivolol. The articles related to the PK of nebivolol were retrieved by searching the five databases; Google Scholar, PubMed, Cochrane Library, ScienceDirect, and EBSCO. A total of 20 studies comprising plasma concentration-t...
Source: Drug Metabolism Reviews - October 18, 2023 Category: Drugs & Pharmacology Authors: Nida Hanif Ammara Zamir Imran Imran Hamid Saeed Abdul Majeed Anees Ur Rehman Waseem Ashraf Faleh Alqahtani Muhammad Fawad Rasool Source Type: research
