Crimean Congo Hemorrhagic Fever Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Crimean-Congo Hemorrhagic Fever Virus Diversity and Reassortment, Pakistan, 2017 –2020
M. Umair et al. (Source: Emerging Infectious Diseases Journal)
Source: Emerging Infectious Diseases Journal - February 28, 2024 Category: Infectious Diseases Source Type: research

Case Management of Imported Crimean-Congo Hemorrhagic Fever, Senegal, July 2023
Y. Gueye et al. (Source: Emerging Infectious Diseases Journal)
Source: Emerging Infectious Diseases Journal - February 28, 2024 Category: Infectious Diseases Source Type: research

Viruses, Vol. 16, Pages 378: A mRNA Vaccine for Crimean & ndash;Congo Hemorrhagic Fever Virus Expressing Non-Fusion GnGc Using NSm Linker Elicits Unexpected Immune Responses in Mice
In conclusion, our results indicated that NSm could be a factor that leads to decreased specific immune responses in the host and should be avoided in the development of CCHFV vaccine antigens. (Source: Viruses)
Source: Viruses - February 28, 2024 Category: Virology Authors: Tong Chen Zhe Ding Xuejie Li Yingwen Li Jiaming Lan Gary Wong Tags: Article Source Type: research

Viruses, Vol. 16, Pages 315: Emergence of Crimean & ndash;Congo Hemorrhagic Fever Virus in Eastern Senegal in 2022
In this study, clinical samples collected through national surveillance systems were screened for acute CCHF virus (CCHFV) infection using RT-PCR and for exposure using ELISA. For any CCHF-positive sample, livestock and tick samples were also collected in the neighborhood of the confirmed case and tested using ELISA and RT-PCR, respectively. Genome sequencing and phylogenetic analyses were also performed on samples with positive RT-PCR results. In Eastern Senegal, two human cases and one Hyalomma tick positive for CCHF were identified and a seroprevalence in livestock ranging from 9.33% to 45.26% was detected. Phylogenetic...
Source: Viruses - February 19, 2024 Category: Virology Authors: Ousseynou Sene Samba Niang Sagne D éthié Ngom Moussa Moise Diagne Aminata Badji Aliou Khoul é El Hadji Ndiaye Safietou Sankhe Cheikh Loucoubar Mawlouth Diallo Manfred Weidmann Ndongo Dia Etienne Simon-Lori ère Yoro Sall Boly Diop Mamadou Ndiaye Anavaj Tags: Article Source Type: research

Detection of Crimean-Congo haemorrhagic fever virus in < em > Hyalomma marginatum < /em > ticks, southern France, May 2022 and April 2023
Euro Surveill. 2024 Feb;29(6):2400023. doi: 10.2807/1560-7917.ES.2024.29.6.2400023.ABSTRACTCrimean-Congo haemorrhagic fever (CCHF), a potentially severe zoonotic viral disease causing fever and haemorrhagic manifestations in humans. As the Crimean-Congo haemorrhagic fever virus (CCHFV) has been detected in ticks in Spain and antibodies against the virus in ruminant sera in Corsica, it was necessary to know more about the situation in France. In 2022-2023, CCHFV was detected in 155 ticks collected from horses and cattle in southern France.PMID:38333936 | PMC:PMC10853980 | DOI:10.2807/1560-7917.ES.2024.29.6.2400023 (Source: Euro Surveill)
Source: Euro Surveill - February 9, 2024 Category: Infectious Diseases Authors: C élia Bernard Charlotte Joly Kukla Ignace Rakotoarivony Maxime Duhayon Fr édéric Stachurski Karine Huber Carla Giupponi Iyonna Zortman Philippe Holzmuller Thomas Pollet M élanie Jeanneau Alice Mercey Nathalie Vachiery Thierry Lefran çois Claire Garr Source Type: research

Detection of Crimean –Congo haemorrhagic fever virus in Hyalomma marginatum ticks, southern France, May 2022 and April 2023
Crimean–Congo haemorrhagic fever (CCHF), a potentially severe zoonotic viral disease causing fever and haemorrhagic manifestations in humans. As the Crimean–Congo haemorrhagic fever virus (CCHFV) has been detected in ticks in Spain and antibodies against the virus in ruminant sera in Corsica, it was necessary to know more about the situation in France. In 2022–2023, CCHFV was detected in 155 ticks collected from horses and cattle in southern France. (Source: Eurosurveillance)
Source: Eurosurveillance - February 8, 2024 Category: Infectious Diseases Authors: C élia Bernard, Charlotte Joly Kukla, Ignace Rakotoarivony, Maxime Duhayon, Frédéric Stachurski, Karine Huber, Carla Giupponi, Iyonna Zortman, Philippe Holzmuller, Thomas Pollet, Mélanie Jeanneau, Alice Mercey, Nathalie Vachiery, Thierry Lefrançois, Source Type: research

Analysis of liver fibrosis equations as a potential role of predictive models in Crimean-Congo hemorrhagic fever
This study aimed to evaluate the diagnostic efficacy of 14 hepatic fibrosis indices for distinguishing fatal cases and intensive care unit requirement (ICU) in CCHF. This study enrolled 194 patients with confirmed CCHF. Laboratory measurements were performed using auto analyzers. Indirect indicators of fibrosis were calculated for each patient based on previously described formulas. Time-dependent receiver operating characteristic (tdROC) curve analyses were employed to evaluate the predictive effects of hepatic fibrosis indices on both intensive care unit requirement and overall survival among patients. Regarding the tdRO...
Source: Acta Tropica - January 13, 2024 Category: Infectious Diseases Authors: Serkan Bolat Seyit Ali B üyüktuna Funda İpekten K übra Doğan G ökmen Zararsız Halef Okan Do ğan Source Type: research

LDLR is an entry receptor for Crimean-Congo hemorrhagic fever virus
Cell Res. 2024 Jan 5. doi: 10.1038/s41422-023-00917-w. Online ahead of print.ABSTRACTCrimean-Congo hemorrhagic fever virus (CCHFV) is the most widespread tick-born zoonotic bunyavirus that causes severe hemorrhagic fever and death in humans. CCHFV enters the cell via clathrin-mediated endocytosis which is dependent on its surface glycoproteins. However, the cellular receptors that are required for CCHFV entry are unknown. Here we show that the low density lipoprotein receptor (LDLR) is an entry receptor for CCHFV. Genetic knockout of LDLR impairs viral infection in various CCHFV-susceptible human, monkey and mouse cells, w...
Source: Cell Research - January 5, 2024 Category: Cytology Authors: Zhi-Sheng Xu Wen-Tian Du Su-Yun Wang Mo-Yu Wang Yi-Ning Yang Yu-Hui Li Zhen-Qi Li Li-Xin Zhao Yan Yang Wei-Wei Luo Yan-Yi Wang Source Type: research