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Health Care Provider Knowledge Regarding Alpha-gal Syndrome - United States, March-May 2022
MMWR Morb Mortal Wkly Rep. 2023 Jul 28;72(30):809-814. doi: 10.15585/mmwr.mm7230a1.ABSTRACTAlpha-gal syndrome (AGS) is an emerging, tick bite-associated immunoglobulin E-mediated allergic condition characterized by a reaction to the oligosaccharide galactose-alpha-1,3-galactose (alpha-gal), which is found in mammalian meat and products derived from mammals, including milk, other dairy products, and some pharmaceutical products. Symptoms range from mild (e.g., a rash or gastrointestinal upset) to severe (anaphylaxis); onset typically occurs ≥2 hours after exposure to alpha-gal. No treatment or cure is currently available....
Source: MMWR Morb Mortal Wkl... - July 27, 2023 Category: Epidemiology Authors: Ann Carpenter Naomi A Drexler David W McCormick Julie M Thompson Gilbert Kersh Scott P Commins Johanna S Salzer Source Type: research

Drug-induced Hypersensitivity Syndrome / Drug Reaction with Eosinophilia and Systemic Symptoms. Part I. Epidemiology, Pathogenesis, Clinicopathological Features, and Prognosis.
Drug-induced hypersensitivity syndrome (DiHS), also known as drug reaction with eosinophilia and systemic symptoms (DRESS), is a severe cutaneous adverse reaction (SCAR) characterized by an exanthem, fever, and hematologic and visceral organ involvement. Anticonvulsants, antibiotics, and allopurinol are the most common triggers. The pathogenesis involves a complex interplay between drugs, viruses, and the immune system primarily mediated by T-cells. DiHS/DRESS typically presents with a morbilliform eruption 2-6 weeks after drug exposure, and is associated with significant morbidity, mortality, and risk of relapse. (Source:...
Source: Journal of the American Academy of Dermatology - July 27, 2023 Category: Dermatology Authors: Brian M. Wei, Lindy P. Fox, Benjamin H. Kaffenberger, Abraham M. Korman, Robert G. Micheletti, Arash Mostaghimi, Megan H. Noe, Misha Rosenbach, Kanade Shinkai, Jason H. Kwah, Elizabeth J. Phillips, Jean L. Bolognia, William Damsky, Caroline A. Nelson Tags: Continuing Medical Education Source Type: research

Drug-induced Hypersensitivity Syndrome / Drug Reaction with Eosinophilia and Systemic Symptoms. Part II. Diagnosis and Management.
Drug-induced hypersensitivity syndrome (DiHS), also known as drug reaction with eosinophilia and systemic symptoms (DRESS), is a severe cutaneous adverse reaction (SCAR) characterized by an exanthem, fever, and hematologic and visceral organ involvement. The differential diagnosis includes other cutaneous adverse reactions, infections, inflammatory and autoimmune diseases, and neoplastic disorders. Three sets of diagnostic criteria have been proposed; however, consensus is lacking. The cornerstone of management is immediate discontinuation of the suspected drug culprit. (Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - July 27, 2023 Category: Dermatology Authors: Brian M. Wei, Lindy P. Fox, Benjamin H. Kaffenberger, Abraham M. Korman, Robert G. Micheletti, Arash Mostaghimi, Megan H. Noe, Misha Rosenbach, Kanade Shinkai, Jason H. Kwah, Elizabeth J. Phillips, Jean L. Bolognia, William Damsky, Caroline A. Nelson Tags: Continuing Medical Education Source Type: research

Drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms. Part I. Epidemiology, pathogenesis, clinicopathological features, and prognosis
Drug-induced hypersensitivity syndrome (DiHS), also known as drug reaction with eosinophilia and systemic symptoms (DRESS), is a severe cutaneous adverse reaction (SCAR) characterized by an exanthem, fever, and hematologic and visceral organ involvement. Anticonvulsants, antibiotics, and allopurinol are the most common triggers. The pathogenesis involves a complex interplay between drugs, viruses, and the immune system primarily mediated by T-cells. DiHS/DRESS typically presents with a morbilliform eruption 2-6 weeks after drug exposure, and is associated with significant morbidity, mortality, and risk of relapse. (Sourc...
Source: Journal of the American Academy of Dermatology - July 27, 2023 Category: Dermatology Authors: Brian M. Wei, Lindy P. Fox, Benjamin H. Kaffenberger, Abraham M. Korman, Robert G. Micheletti, Arash Mostaghimi, Megan H. Noe, Misha Rosenbach, Kanade Shinkai, Jason H. Kwah, Elizabeth J. Phillips, Jean L. Bolognia, William Damsky, Caroline A. Nelson Tags: Continuing medical education Source Type: research

Drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms. Part II diagnosis and management
Drug-induced hypersensitivity syndrome, also known as drug reaction with eosinophilia and systemic symptoms, is a severe cutaneous adverse reaction characterized by an exanthem, fever, and hematologic and visceral organ involvement. The differential diagnosis includes other cutaneous adverse reactions, infections, inflammatory and autoimmune diseases, and neoplastic disorders. Three sets of diagnostic criteria have been proposed; however, consensus is lacking. The cornerstone of management is immediate discontinuation of the suspected drug culprit. (Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - July 27, 2023 Category: Dermatology Authors: Brian M. Wei, Lindy P. Fox, Benjamin H. Kaffenberger, Abraham M. Korman, Robert G. Micheletti, Arash Mostaghimi, Megan H. Noe, Misha Rosenbach, Kanade Shinkai, Jason H. Kwah, Elizabeth J. Phillips, Jean L. Bolognia, William Damsky, Caroline A. Nelson Tags: Continuing medical education Source Type: research

Erratum to Continuing Medical Education Pediatric Hypertension: An Update on the American Academy of Pediatrics Clinical Practice Guidelines
The publisher regrets that contact hours cannot be provided for this Continuing Education article. For a few of the questions, the correct answers were provided on the posttest and for one question two answers were the same. The posttest errors should not reflect upon the authors. The contents of the article itself are evidence-based and a scientifically correct analysis of the best available evidence reported in the AAP's hypertension clinical practice guideline. The contact hours have been updated in the original article to reflect this change. (Source: Journal of Pediatric Health Care)
Source: Journal of Pediatric Health Care - July 25, 2023 Category: Pediatrics Authors: Kelsey Pearson, Susan M. Halbach Tags: Erratum Source Type: research

Events of Interest
News items of interest to the vascular surgeon must be received at least 8 weeks before the desired month of publication. Announcements published at no charge include those received from a sponsoring society of this Journal, those courses and conferences sponsored by state, regional, national, or international vascular surgical organizations, and university-sponsored continuing medical education courses. Send applicable events to Andrew O ’Brien, Journal Manager, at a.obrien@elsevier.com. All other news items selected for publication carry a charge of $60.00 US for each insertion, and the fee must accompany the request t...
Source: Journal of Vascular Surgery - July 20, 2023 Category: Surgery Source Type: research

CME Exam 1: Effect of Helicobacter pylori Eradication Therapy on the Incidence of Noncardia Gastric Adenocarcinoma in a Large Diverse Population in the United States
(Source: Gastroenterology)
Source: Gastroenterology - July 19, 2023 Category: Gastroenterology Tags: Continuing Medical Education (CME)/MOC Activities Source Type: research

Answers to CME examination
(Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - July 15, 2023 Category: Dermatology Tags: Continuing medical education Source Type: research

CME examination
(Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - July 15, 2023 Category: Dermatology Tags: Continuing medical education Source Type: research

Exploring Family Physician Training Needs to Improve Cancer Patient Care
This study explored the needs and perspectives of family physicians regarding their oncology training and experiences. As well, physician cancer care experiences, knowledge use, and continuing education practices were elucidated. The authors employed a qualitative approach with family physicians participating in semi-structured interviews. General practitioners in oncology were excluded. Purposeful sampling was used, with recruitment through Ontario regional primary cancer care leads and social media. Interviews were transcribed, and thematic analysis was conducted. Thirteen participants were interviewed —1.6:1 female: m...
Source: Journal of Cancer Education - July 14, 2023 Category: Cancer & Oncology Source Type: research

Continuing Medical Education
Transfusion. 2023 Jul;63(7):1391. doi: 10.1111/trf.17470.NO ABSTRACTPMID:37439100 | DOI:10.1111/trf.17470 (Source: Transfusion)
Source: Transfusion - July 13, 2023 Category: Hematology Source Type: research