Peptoid Oligomers Target Viral Membranes
Researchers at New York University have developed a new method to target many viruses that cause disease. For viruses with a lipid membrane, which includes many that commonly cause disease, this new technique could prove to be fatal. By targeting the lipid membrane, the approach may circumvent the treatment resistance that arises when viruses mutate to alter their surface proteins, which are the most common targets for conventional anti-viral drugs. This new approach is based on a synthetic version of antimicrobial peptides, which are naturally produced by our immune system and can target pathogens such as bacteria and vir...
Source: Medgadget - August 30, 2023 Category: Medical Devices Authors: Conn Hastings Tags: Medicine Public Health Source Type: blogs

Harvard Health Ad Watch: An arthritis ad in 4 parts
Perhaps you’ve grown as weary as I have of repeated arthritis ads. They appear in frequent rotation on television, online, and in magazines, promoting Enbrel, Humira, Otezla, Xeljanz, and others. If you’ve actually read or listened to these ads, you might have felt perplexed at certain points. Here’s a quick rundown on what they’re saying — and not saying — in one of those ads. “The clock is ticking” Part 1: A teakettle whistles on the stove and a disembodied voice speaks as this ad for Humira opens. “This is your wakeup call. If you have moderate to severe rheumatoid arthritis, month after month the cloc...
Source: Harvard Health Blog - April 29, 2020 Category: Consumer Health News Authors: Robert H. Shmerling, MD Tags: Arthritis Bones and joints Health Inflammation Source Type: blogs

Harvard Health AdWatch: An arthritis ad in 4 parts
Perhaps you’ve grown as weary as I have of repeated arthritis ads. They appear in frequent rotation on television, online, and in magazines, promoting Enbrel, Humira, Otezla, Xeljanz, and others. If you’ve actually read or listened to these ads, you might have felt perplexed at certain points. Here’s a quick rundown on what they’re saying — and not saying — in one of those ads. “The clock is ticking” Part 1: A teakettle whistles on the stove and a disembodied voice speaks as this ad for Humira opens. “This is your wakeup call. If you have moderate to severe rheumatoid arthritis, month after month the cloc...
Source: Harvard Health Blog - April 29, 2020 Category: Consumer Health News Authors: Robert H. Shmerling, MD Tags: Arthritis Bones and joints Health Inflammation Source Type: blogs

Coronavirus: the human factor in intensive care
The summer of 1979 is permanently etched into my memory. I walked into the intensive care unit as a newly minted intern. I walked over to ICU-Bed 1 to be introduced to my first patient, a frail teenaged boy who was tethered to a ventilator. “He is day 30 with respiratory failure from disseminated coccidioidomycosis,” […]Find jobs at  Careers by KevinMD.com.  Search thousands of physician, PA, NP, and CRNA jobs now.  Learn more. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - March 21, 2020 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/lawrence-hurwitz" rel="tag" > Lawrence Hurwitz, MD < /a > < /span > Tags: Conditions COVID-19 coronavirus Infectious Disease Source Type: blogs

Coccidioidomycosis in the United States
Although largely limited to the western and southwestern states, Coccidioidomycosis is more commonly reported than legionellosis. More Americans die from Coccidioidomycosis than from the other two regional mycoses, Blastomycosis and Histoplasmosis. [1,2]   While Coccidioidomycosis is best known as a disease of California (“Valley Fever”) , highest incidence is reported from Arizona.  These data are even more striking when adjusted for relative population size (cases per 100,000 population).   References: Berger S. Infectious Diseases of the United States, 2019. 1,422 pages , 513 graphs , 18,048 re...
Source: GIDEON blog - September 4, 2019 Category: Databases & Libraries Authors: Dr. Stephen Berger Tags: Ebooks Epidemiology Graphs ProMED Source Type: blogs

Pediatric Conjunctivitis a Simple Diagnosis Until It Isn’t
​Conjunctivitis is a common condition and easy enough to treat, but several uncommon conjunctivitis syndromes require more care and should not be missed.Conjunctivitis is either infectious (viral or bacterial) or noninfectious (allergic or nonallergic). Viral infections are more common in adults, bacterial ones in children, usually caused by Staphylococcus aureus, Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis. Adults tend to have more S. aureus infections, while the other pathogens are more common in children. An adenovirus is typically responsible for viral-associated infections in conjunct...
Source: M2E Too! Mellick's Multimedia EduBlog - March 1, 2019 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs

Answer to Case 506
Answer: Hard tick, Hyalommasp.As many of you noted, this is one of the " Old World " ticks found in many parts of North Africa, South Africa, the Middle East, Asia, and Europe.Here are a few important facts about this tick :They are one of the most medically important ticks in the Old World. Important species includeHyalomma marginatum(MediterraneanHyalomma), H. trucantum, H. asiaticum, H. excavatum, H. aegyptium, H. scupense andH. rufipes. They are vectors for several important disease agents, including Crimean-Congo hemorrhagic fever virus, several Rickettsia spp., Anaplasma phagoc...
Source: Creepy Dreadful Wonderful Parasites - August 12, 2018 Category: Parasitology Source Type: blogs

Job: Environmental Microbiology – UC Riverside
UC Riverside faculty position in Environmental Microbiology part of Hiring Cluster BREATHE: Environ./Medical Microbiology, Environ./Medical History, Pulmonary Physiology, Pulmonary/Mucosal Immunol Job #JPF00639 School of Medicine – Biomedical Sciences Environmental Microbiology – experience working in natural systems, and in soil and/or air microbial ecology. A range of expertise between bacterial, archaeal, and fungal organisms, is preferred, including aeromicrobiology, and organisms with airborne spores (e.g., Coccidioides, Aspergilli, Pseudomonas, Clostridium, etc.). In addition, the environmental microbiolo...
Source: Fungal Genomes and Comparative Genomics - December 6, 2016 Category: Genetics & Stem Cells Authors: Jason Stajich Tags: jobs aspergillus BREATHE coccidioides microbiology UCRiverside Source Type: blogs

You ’ ve Got Questions, We ’ ve Got Answers: Cell Day 2016
Students from Connecticut to Washington State and points in between peppered our experts with questions during the recent live Cell Day web chat. They fielded questions about cell structures, microscopes and other tools, life as a scientist, and whether there are still discoveries to be made in cell biology. One of the Cell Day moderators, Jessica Faupel-Badger, even gave a shout-out to the Biomedical Beat blog as a great way to keep up with new and exciting discoveries being made every day. Thanks! The full transcript with all the questions and answers is now available. We’ve recapped some of the highlights below. [...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - December 1, 2016 Category: Research Authors: Anne Oplinger Tags: Being a Scientist Cell Biology Source Type: blogs

To Improve Pandemic Preparedness, Update The Priority Review Voucher Program
Legislation recently introduced in the U.S. House of Representatives would add the Zika virus to the list of diseases in the Food and Drug Administration’s (FDA) priority review voucher (PRV) program. The Senate HELP Committee has also recently advanced similar legislation. This is a positive step that would help incentivize needed research and development (R&D) to fight the disease. However, it also illustrates the fact that the PRV platform could be used far more proactively to help address future pandemics before they strike. Incentive For Innovation In 2007 the US government created the PRV as an incentive to dri...
Source: Health Affairs Blog - March 22, 2016 Category: Health Management Authors: Kenneth Gustavsen Tags: Drugs and Medical Technology Featured Global Health Congress Ebola FDA outbreaks pandemic priority review Research Zika Source Type: blogs

Arthropod-borne Viruses of Senegal
A recent outbreak of suspected viral infection in Kedougou Region (http://www.promedmail.org/direct.php?id=3626668) highlights the complexity of establishing a specific etiological agent in West Africa.  At least twenty arthropod-borne viruses are associated with known or suspected human infection in Senegal.  The following alphabetical list is abstracted from Gideon www.GideonOnline.com and the Gideon e-book series [1]   (Primary references are available from Dr. Berger on request) Bagaza – Bagaza virus has been recovered from mosquitoes in Senegal (Aedes fowleri, Culex neavei, Cx. Poicilipes and Mansonia, Mimomyia ...
Source: GIDEON blog - September 6, 2015 Category: Databases & Libraries Authors: Dr. Stephen Berger Tags: Ebooks Epidemiology Outbreaks ProMED Senegal Source Type: blogs

Guest post by Lizzy Wilbanks: Story behind the paper "Microscale sulfur cycling in the phototrophic pink berry consortia of the Sippewissett Salt Marsh"
Conclusions:Using the pink berries, we demonstrate how an integrative microbiological and microgeochemical approach can be used to decrypt the microbial metabolic partnerships that drive sulfur cycling at the microscale. This methodology, which may ultimately be used to examine more complex ecosystems, offers direct evidence of syntrophic interspecies sulfur transfer. For more details on how all these different pieces came together, you'll just have to check out our paper yourself!   FAQ:What do they taste like?Mostly just salty, and a bit sandy :)Are the pink berries found anywhere else?Not really!  I...
Source: The Tree of Life - March 5, 2014 Category: Medical Scientists Authors: Jonathan Eisen Source Type: blogs

Climate Change and Disease: USA Today Gets It Wrong
This report describes statistically significant increases in the incidence rate of reported coccidioidomycosis in endemic states during 1998–2011 after adjusting for changes in population size and in age and sex distribution. Although the number of cases decreased in Arizona during 2007–2008 and in California during 2007–2009, incidence dramatically increased in 2010 and 2011. In 2011, coccidioidomycosis was the second most commonly reported nationally notifiable condition in Arizona and the fourth most commonly reported in California. The reasons for the increases described in this report are unclear. Coccidioides e...
Source: Cato-at-liberty - December 16, 2013 Category: Health Medicine and Bioethics Commentators Authors: Patrick J. Michaels, Paul C. "Chip" Knappenberger Source Type: blogs

Medical Mispronunciations and Misspelled Words: The Definitive List.
Hearing medical mispronunciations and seeing misspelled words are an under appreciated  joy of working in healthcare.  Physicians often forget just how alien the language of medicine is to people who don't live it everyday.  The best part about being a physician is not helping people recover from critical illness. The best part is not  about  listening and understanding with compassion and empathy.  Nope, the best part about being a physician is hearing patients and other healthcare providers butcher the language of medicine and experiencing great entertainment in the process.   Doctors c...
Source: The Happy Hospitalist - October 2, 2013 Category: Internists and Doctors of Medicine Authors: Tamer Mahrous Source Type: blogs

Notifiable diseases in the US for 2011
The US Centers for Disease Control and Prevention has released a summary of notifiable diseases in the US for the year 2011. These statistics are collected and compiled from reports sent by state health departments and territories to the National Notifiable Diseases Surveillance System (NNDSS). According to the CDC, a notifiable disease is one for which regular, frequent, and timely information regarding individual cases is considered necessary for the prevention and control of the disease. The list of nationally notifiable infectious diseases is dynamic, as new diseases are added and others deleted as incidence declines...
Source: virology blog - July 9, 2013 Category: Virology Authors: Vincent Racaniello Tags: Information CDC centers for disease control notifiable disease viral virology virus Source Type: blogs