An integrated in vitro approach on the enzymatic and antioxidant mechanisms of four commercially available essential oils (Copaifera officinalis, Gaultheria fragrantissima, Helichrysum italicum, and Syzygium aromaticum) traditionally used topically for their anti-inflammatory effects
Conclusion: More studies are needed to describe the essential oils properties, but these results confirm the potential of these essential oils as anti-inflammatory and antioxidant agents. (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - January 29, 2024 Category: Drugs & Pharmacology Source Type: research
Disparities in Olfactory Dysfunction in African Americans
CONCLUSION: On both tests of olfaction, AA performed worse than Whites and a greater proportion of AA were considered hyposmic compared to Whites. This is a discrepancy with self-reported olfaction, which showed no difference between Whites and AA. AA performed significantly worse than their White counterparts on several scents, with possible implications regarding cultural appropriateness of scents used in olfactory testing.PMID:38235801 | DOI:10.1177/00034894231222693 (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - January 18, 2024 Category: ENT & OMF Authors: Nicholas J Choi Kevin J Sykes Mark Villwock Jennifer Villwock Source Type: research
Establishing a safe anesthesia concentration window for Nile tilapia (Oreochromis niloticus) (Linnaeus 1758) by monitoring cardiac activity in eugenol immersion baths
Comp Biochem Physiol C Toxicol Pharmacol. 2024 Jan 11;278:109839. doi: 10.1016/j.cbpc.2024.109839. Online ahead of print.ABSTRACTNile tilapia, Oreochromis niloticus, is the most cultivated fish species in the world, due to its low cost, high growth rate, environmental adaptability, and resistance to disease and stress. Anesthetics for fish become necessary in management because they minimize mortality during transport and maintenance of ponds, one of the most used anesthetics is clove oil, which has eugenol as the major substance, representing 90-95 % of clove oil. The present study evaluates the effect of eugenol on cardi...
Source: Comparative biochemistry and physiology. Toxicology and pharmacology : CBP - January 13, 2024 Category: Biochemistry Authors: Clarissa Araujo da Paz Brenda Maria Pereira Alho da Costa Maria Klara Otake Hamoy Murilo Farias Dos Santos Lucas Lima da Rocha Yris da Silva Deiga Anara de Sousa Barbosa Anthony Lucas Gurgel do Amaral Tays Mata C âmara Gabriela Brito Barbosa Daniella Bas Source Type: research
Insights into the mechanisms of diabetic wounds: pathophysiology, molecular targets, and treatment strategies through conventional and alternative therapies
AbstractDiabetes mellitus is a prevalent cause of mortality worldwide and can lead to several secondary issues, including DWs, which are caused by hyperglycemia, diabetic neuropathy, anemia, and ischemia. Roughly 15% of diabetic patient ’s experience complications related to DWs, with 25% at risk of lower limb amputations. A conventional management protocol is currently used for treating diabetic foot syndrome, which involves therapy using various substances, such as bFGF, pDGF, VEGF, EGF, IGF-I, TGF-β, skin substitutes, cytokin e stimulators, cytokine inhibitors, MMPs inhibitors, gene and stem cell therapies, ECM, and ...
Source: Inflammopharmacology - January 11, 2024 Category: Drugs & Pharmacology Source Type: research
Mefenamic Acid Loaded and TPGS Stabilized Mucoadhesive Nanoemulsion for the Treatment of Alzheimer's Disease: Development, Optimization, and Brain-Targeted Delivery via Olfactory Pathway
AAPS PharmSciTech. 2024 Jan 10;25(1):16. doi: 10.1208/s12249-023-02727-0.ABSTRACTAlzheimer's disease (AD) is a very common disorder that affects the elderly. There are relatively few medications that can be used orally or as a suspension to treat AD. A mucoadhesive (o/w) nano emulsion of mefenamic acid was made by adding Carbopol 940P to the optimised drug nanoemulsion using distilled water as the aqueous phase (6%); Solutol HS: tween 20 (3.6%) as the surfactant and co-surfactant; and clove oil: TPGS (0.4%) as the oil phase and mefenamic acid as the drug (2.8 mg/ml). The mucoadhesive nanoemulsion (S40.5%w/v) had a particle...
Source: AAPS PharmSciTech - January 10, 2024 Category: Drugs & Pharmacology Authors: Anmol Dogra Ramandeep Singh Narang Tajpreet Kaur Jasjeet Kaur Narang Source Type: research
Gender minority stress and diurnal cortisol profiles among transgender and gender diverse people in the United States
Horm Behav. 2024 Jan 7;159:105473. doi: 10.1016/j.yhbeh.2023.105473. Online ahead of print.ABSTRACTThe field of behavioral neuroendocrinology has only begun to explore the lived experiences of transgender and gender diverse (TGD) people exposed to stigma. In light of escalating attacks and legislation targeting TGD people in the United States, it is crucial to examine the physiological pathways through which gender minority stressors become embodied, impact health, and contribute to health inequities. The Trans Resilience and Health Study included baseline data collection from fall 2019 to spring 2020 from a sample of 124 ...
Source: Hormones and Behavior - January 8, 2024 Category: Endocrinology Authors: L Zachary DuBois Jae A Puckett Dee Jolly Sally Powers Tian Walker Debra A Hope Richard Mocarski T Zachary Huit Brenna R Lash Natalie Holt Allura Ralston Makinna Miles A Capannola Clove Tipton Geeta Eick Robert-Paul Juster Source Type: research
Pharmacodynamic, pharmacokinetic, toxicity, and recent advances in Eugenol's potential benefits against natural and chemical noxious agents: A mechanistic review
Toxicon. 2024 Jan 6:107607. doi: 10.1016/j.toxicon.2024.107607. Online ahead of print.ABSTRACTThe active biological phytochemicals, crucial compounds employed in creating hundreds of medications, are derived from valuable and medicinally significant plants. These phytochemicals offer excellent protection from various illnesses, including inflammatory disorders and chronic conditions caused by oxidative stress. A phenolic monoterpenoid known as eugenol (EUG), it is typically found in the essential oils of many plant species from the Myristicaceae, Myrtaceae, Lamiaceae, and Lauraceae families. One of the main ingredients of ...
Source: Toxicon - January 8, 2024 Category: Toxicology Authors: Negin Tavvabi-Kashani Maede Hasanpour Vafa Baradaran Rahimi Naser Vahdati-Mashhadian Vahid Reza Askari Source Type: research
Gender minority stress and diurnal cortisol profiles among transgender and gender diverse people in the United States
Horm Behav. 2024 Jan 7;159:105473. doi: 10.1016/j.yhbeh.2023.105473. Online ahead of print.ABSTRACTThe field of behavioral neuroendocrinology has only begun to explore the lived experiences of transgender and gender diverse (TGD) people exposed to stigma. In light of escalating attacks and legislation targeting TGD people in the United States, it is crucial to examine the physiological pathways through which gender minority stressors become embodied, impact health, and contribute to health inequities. The Trans Resilience and Health Study included baseline data collection from fall 2019 to spring 2020 from a sample of 124 ...
Source: Hormones and Behavior - January 8, 2024 Category: Endocrinology Authors: L Zachary DuBois Jae A Puckett Dee Jolly Sally Powers Tian Walker Debra A Hope Richard Mocarski T Zachary Huit Brenna R Lash Natalie Holt Allura Ralston Makinna Miles A Capannola Clove Tipton Geeta Eick Robert-Paul Juster Source Type: research
Pharmacodynamic, pharmacokinetic, toxicity, and recent advances in Eugenol's potential benefits against natural and chemical noxious agents: A mechanistic review
Toxicon. 2024 Feb 1;238:107607. doi: 10.1016/j.toxicon.2024.107607. Epub 2024 Jan 7.ABSTRACTThe active biological phytochemicals, crucial compounds employed in creating hundreds of medications, are derived from valuable and medicinally significant plants. These phytochemicals offer excellent protection from various illnesses, including inflammatory disorders and chronic conditions caused by oxidative stress. A phenolic monoterpenoid known as eugenol (EUG), it is typically found in the essential oils of many plant species from the Myristicaceae, Myrtaceae, Lamiaceae, and Lauraceae families. One of the main ingredients of cl...
Source: Toxicon - January 8, 2024 Category: Toxicology Authors: Negin Tavvabi-Kashani Maede Hasanpour Vafa Baradaran Rahimi Naser Vahdati-Mashhadian Vahid Reza Askari Source Type: research
Insecticidal plants as trade opportunities and use by small vegetable producers: an example using essential oils to control Diaphania hyalinata (Lepidoptera: Crambidae)
The objective of this study was to evaluate the toxicity of essential oils to Diaphania hyalinata (Lepidoptera: Crambidae) and to show regions with the potential to use Cinnamomum zeylanicum, Citrus sinensis, and Syzygium aromaticum in the formulation and commercialization of insecticides to control this insect. The C. zeylanicum oil was more toxic to larvae and pupae and the S. aromaticum to eggs of D. hyalinata. Essential oils are an alternative for the management of D. hyalinata. The production of pesticides from essential oils of C. zeylanicum, C. sinensis, and S. aromaticum to control D. hyalinata has high potential i...
Source: An Acad Bras Cienc - December 21, 2023 Category: Science Authors: Isabel M DA Silva Jos é E Serrão Marinalva M Dos Santos Ricardo S DA Silva Am élia G DE Carvalho Evaldo M Pires Jos é C Zanuncio Marcus A Soares Source Type: research
Insecticidal plants as trade opportunities and use by small vegetable producers: an example using essential oils to control Diaphania hyalinata (Lepidoptera: Crambidae)
The objective of this study was to evaluate the toxicity of essential oils to Diaphania hyalinata (Lepidoptera: Crambidae) and to show regions with the potential to use Cinnamomum zeylanicum, Citrus sinensis, and Syzygium aromaticum in the formulation and commercialization of insecticides to control this insect. The C. zeylanicum oil was more toxic to larvae and pupae and the S. aromaticum to eggs of D. hyalinata. Essential oils are an alternative for the management of D. hyalinata. The production of pesticides from essential oils of C. zeylanicum, C. sinensis, and S. aromaticum to control D. hyalinata has high potential i...
Source: An Acad Bras Cienc - December 21, 2023 Category: Science Authors: Isabel M DA Silva Jos é E Serrão Marinalva M Dos Santos Ricardo S DA Silva Am élia G DE Carvalho Evaldo M Pires Jos é C Zanuncio Marcus A Soares Source Type: research
Insecticidal plants as trade opportunities and use by small vegetable producers: an example using essential oils to control Diaphania hyalinata (Lepidoptera: Crambidae)
The objective of this study was to evaluate the toxicity of essential oils to Diaphania hyalinata (Lepidoptera: Crambidae) and to show regions with the potential to use Cinnamomum zeylanicum, Citrus sinensis, and Syzygium aromaticum in the formulation and commercialization of insecticides to control this insect. The C. zeylanicum oil was more toxic to larvae and pupae and the S. aromaticum to eggs of D. hyalinata. Essential oils are an alternative for the management of D. hyalinata. The production of pesticides from essential oils of C. zeylanicum, C. sinensis, and S. aromaticum to control D. hyalinata has high potential i...
Source: An Acad Bras Cienc - December 21, 2023 Category: Science Authors: Isabel M DA Silva Jos é E Serrão Marinalva M Dos Santos Ricardo S DA Silva Am élia G DE Carvalho Evaldo M Pires Jos é C Zanuncio Marcus A Soares Source Type: research
Insecticidal plants as trade opportunities and use by small vegetable producers: an example using essential oils to control Diaphania hyalinata (Lepidoptera: Crambidae)
The objective of this study was to evaluate the toxicity of essential oils to Diaphania hyalinata (Lepidoptera: Crambidae) and to show regions with the potential to use Cinnamomum zeylanicum, Citrus sinensis, and Syzygium aromaticum in the formulation and commercialization of insecticides to control this insect. The C. zeylanicum oil was more toxic to larvae and pupae and the S. aromaticum to eggs of D. hyalinata. Essential oils are an alternative for the management of D. hyalinata. The production of pesticides from essential oils of C. zeylanicum, C. sinensis, and S. aromaticum to control D. hyalinata has high potential i...
Source: An Acad Bras Cienc - December 21, 2023 Category: Science Authors: Isabel M DA Silva Jos é E Serrão Marinalva M Dos Santos Ricardo S DA Silva Am élia G DE Carvalho Evaldo M Pires Jos é C Zanuncio Marcus A Soares Source Type: research
Insecticidal plants as trade opportunities and use by small vegetable producers: an example using essential oils to control Diaphania hyalinata (Lepidoptera: Crambidae)
The objective of this study was to evaluate the toxicity of essential oils to Diaphania hyalinata (Lepidoptera: Crambidae) and to show regions with the potential to use Cinnamomum zeylanicum, Citrus sinensis, and Syzygium aromaticum in the formulation and commercialization of insecticides to control this insect. The C. zeylanicum oil was more toxic to larvae and pupae and the S. aromaticum to eggs of D. hyalinata. Essential oils are an alternative for the management of D. hyalinata. The production of pesticides from essential oils of C. zeylanicum, C. sinensis, and S. aromaticum to control D. hyalinata has high potential i...
Source: An Acad Bras Cienc - December 21, 2023 Category: Science Authors: Isabel M DA Silva Jos é E Serrão Marinalva M Dos Santos Ricardo S DA Silva Am élia G DE Carvalho Evaldo M Pires Jos é C Zanuncio Marcus A Soares Source Type: research
Insecticidal plants as trade opportunities and use by small vegetable producers: an example using essential oils to control Diaphania hyalinata (Lepidoptera: Crambidae)
The objective of this study was to evaluate the toxicity of essential oils to Diaphania hyalinata (Lepidoptera: Crambidae) and to show regions with the potential to use Cinnamomum zeylanicum, Citrus sinensis, and Syzygium aromaticum in the formulation and commercialization of insecticides to control this insect. The C. zeylanicum oil was more toxic to larvae and pupae and the S. aromaticum to eggs of D. hyalinata. Essential oils are an alternative for the management of D. hyalinata. The production of pesticides from essential oils of C. zeylanicum, C. sinensis, and S. aromaticum to control D. hyalinata has high potential i...
Source: An Acad Bras Cienc - December 21, 2023 Category: Science Authors: Isabel M DA Silva Jos é E Serrão Marinalva M Dos Santos Ricardo S DA Silva Am élia G DE Carvalho Evaldo M Pires Jos é C Zanuncio Marcus A Soares Source Type: research
