Effect of Nonpharmacological Methods on Pruritus in Patients with Liver Disease and Liver Cirrhosis: Systematic Review
CONCLUSIONS: Based on the findings, nonpharmacological methods have a positive effect on itching in individuals with liver disease and liver cirrhosis. It is recommended to conduct more studies with higher methodological quality, using larger sample groups, different interventions, randomization, and blinding methods, to examine the effectiveness of nonpharmacological methods in patients with liver disease and liver cirrhosis.PMID:38702165 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - May 3, 2024 Category: Complementary Medicine Authors: Yasemin Çayir Meral G ün Emine Kaplan Serin Source Type: research

Effect of Nonpharmacological Methods on Pruritus in Patients with Liver Disease and Liver Cirrhosis: Systematic Review
CONCLUSIONS: Based on the findings, nonpharmacological methods have a positive effect on itching in individuals with liver disease and liver cirrhosis. It is recommended to conduct more studies with higher methodological quality, using larger sample groups, different interventions, randomization, and blinding methods, to examine the effectiveness of nonpharmacological methods in patients with liver disease and liver cirrhosis.PMID:38702165 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - May 3, 2024 Category: Complementary Medicine Authors: Yasemin Çayir Meral G ün Emine Kaplan Serin Source Type: research

Unraveling molecular advancements in chordoma tumorigenesis and treatment response: a review of scientific discoveries and clinical implications
Neurosurg Focus. 2024 May;56(5):E18. doi: 10.3171/2024.2.FOCUS2417.ABSTRACTChordomas are tumors thought to originate from notochordal remnants that occur in midline structures from the cloves of the skull base to the sacrum. In adults, the most common location is the sacrum, followed by the clivus and then mobile spine, while in children a clival origin is most common. Most chordomas are slow growing. Clinical presentation of chordomas tend to occur late, with local invasion and large size often complicating surgical intervention. Radiation therapy with protons has been proven to be an effective adjuvant therapy. Unfortuna...
Source: Neurosurgical Focus - May 1, 2024 Category: Neurosurgery Authors: Michael C Jin Ian D Connolly Karthik Ravi Daniel G Tobert Shannon M MacDonald John H Shin Source Type: research

A novel biopolymeric composite edible film based on sunnhemp protein isolate and potato starch incorporated with clove oil: Fabrication, characterization, and amino acid composition
Int J Biol Macromol. 2024 Apr 29:131940. doi: 10.1016/j.ijbiomac.2024.131940. Online ahead of print.ABSTRACTComposite edible films were developed by casting method using sunnhemp protein isolate (SHPI) and potato starch (PS) at various proportions (100:0, 90:10, 80:20; 70:30, 60:40, and 50:50) containing glycerol as a plasticizer and clove oil. All the edible films were evaluated for thickness, moisture content, solubility, swelling ratio, water activity. Further characterization of edible films was done on the basis of mechanical, optical, thermal and structural attributes along with morphology. Among all the films, compo...
Source: International Journal of Biological Macromolecules - May 1, 2024 Category: Biochemistry Authors: Rashmi Rawat Charanjiv Singh Saini Source Type: research

Unraveling molecular advancements in chordoma tumorigenesis and treatment response: a review of scientific discoveries and clinical implications
Neurosurg Focus. 2024 May;56(5):E18. doi: 10.3171/2024.2.FOCUS2417.ABSTRACTChordomas are tumors thought to originate from notochordal remnants that occur in midline structures from the cloves of the skull base to the sacrum. In adults, the most common location is the sacrum, followed by the clivus and then mobile spine, while in children a clival origin is most common. Most chordomas are slow growing. Clinical presentation of chordomas tend to occur late, with local invasion and large size often complicating surgical intervention. Radiation therapy with protons has been proven to be an effective adjuvant therapy. Unfortuna...
Source: Neurosurgical Focus - May 1, 2024 Category: Neurosurgery Authors: Michael C Jin Ian D Connolly Karthik Ravi Daniel G Tobert Shannon M MacDonald John H Shin Source Type: research

Unraveling molecular advancements in chordoma tumorigenesis and treatment response: a review of scientific discoveries and clinical implications
Neurosurg Focus. 2024 May;56(5):E18. doi: 10.3171/2024.2.FOCUS2417.ABSTRACTChordomas are tumors thought to originate from notochordal remnants that occur in midline structures from the cloves of the skull base to the sacrum. In adults, the most common location is the sacrum, followed by the clivus and then mobile spine, while in children a clival origin is most common. Most chordomas are slow growing. Clinical presentation of chordomas tend to occur late, with local invasion and large size often complicating surgical intervention. Radiation therapy with protons has been proven to be an effective adjuvant therapy. Unfortuna...
Source: Neurosurgical Focus - May 1, 2024 Category: Neurosurgery Authors: Michael C Jin Ian D Connolly Karthik Ravi Daniel G Tobert Shannon M MacDonald John H Shin Source Type: research

Unraveling molecular advancements in chordoma tumorigenesis and treatment response: a review of scientific discoveries and clinical implications
Neurosurg Focus. 2024 May;56(5):E18. doi: 10.3171/2024.2.FOCUS2417.ABSTRACTChordomas are tumors thought to originate from notochordal remnants that occur in midline structures from the cloves of the skull base to the sacrum. In adults, the most common location is the sacrum, followed by the clivus and then mobile spine, while in children a clival origin is most common. Most chordomas are slow growing. Clinical presentation of chordomas tend to occur late, with local invasion and large size often complicating surgical intervention. Radiation therapy with protons has been proven to be an effective adjuvant therapy. Unfortuna...
Source: Neurosurgical Focus - May 1, 2024 Category: Neurosurgery Authors: Michael C Jin Ian D Connolly Karthik Ravi Daniel G Tobert Shannon M MacDonald John H Shin Source Type: research

In vivo determination of the anti-inflammatory and antioxidant effects of the aqueous extract of Syzygium aromaticum (clove) in an asthmatic rat model
This study aimed to evaluate the anti-inflammatory and antioxidant effects of an Aqueous Extract of Clove (AEC) Syzygium aromaticum on the lungs and erythrocytes of an experimental asthma model in Wistar rats. For this purpose, four groups of male rats were examined: control, sensitized with ovalbumin (OVA), treated with AEC, and treated with a combination of OVA/AEC. After treatment, the antioxidant effect was determined by measuring the malondialdehyde (MDA), glutathione peroxidase (GPx), glutathione (GSH), and catalase (CAT) levels. The anti-inflammatory effect was determined by measuring IL-4 levels by performing enzym...
Source: Cellular and Molecular Biology - April 23, 2024 Category: Molecular Biology Authors: Lynda Sabrina Ounaceur Mahfoud Messarah Abdelaziz Lankar Djihane Touaibia Hanene Ghadab Zohir Garri Sonia Boudjil Khadidja Belkacem Djeffel Latifa Atoui Anis Ounaceur Nesrine Djaber Amel Boumendjel Source Type: research

In vivo determination of the anti-inflammatory and antioxidant effects of the aqueous extract of Syzygium aromaticum (clove) in an asthmatic rat model
This study aimed to evaluate the anti-inflammatory and antioxidant effects of an Aqueous Extract of Clove (AEC) Syzygium aromaticum on the lungs and erythrocytes of an experimental asthma model in Wistar rats. For this purpose, four groups of male rats were examined: control, sensitized with ovalbumin (OVA), treated with AEC, and treated with a combination of OVA/AEC. After treatment, the antioxidant effect was determined by measuring the malondialdehyde (MDA), glutathione peroxidase (GPx), glutathione (GSH), and catalase (CAT) levels. The anti-inflammatory effect was determined by measuring IL-4 levels by performing enzym...
Source: Mol Biol Cell - April 23, 2024 Category: Molecular Biology Authors: Lynda Sabrina Ounaceur Mahfoud Messarah Abdelaziz Lankar Djihane Touaibia Hanene Ghadab Zohir Garri Sonia Boudjil Khadidja Belkacem Djeffel Latifa Atoui Anis Ounaceur Nesrine Djaber Amel Boumendjel Source Type: research

In vivo determination of the anti-inflammatory and antioxidant effects of the aqueous extract of Syzygium aromaticum (clove) in an asthmatic rat model
This study aimed to evaluate the anti-inflammatory and antioxidant effects of an Aqueous Extract of Clove (AEC) Syzygium aromaticum on the lungs and erythrocytes of an experimental asthma model in Wistar rats. For this purpose, four groups of male rats were examined: control, sensitized with ovalbumin (OVA), treated with AEC, and treated with a combination of OVA/AEC. After treatment, the antioxidant effect was determined by measuring the malondialdehyde (MDA), glutathione peroxidase (GPx), glutathione (GSH), and catalase (CAT) levels. The anti-inflammatory effect was determined by measuring IL-4 levels by performing enzym...
Source: Cellular and Molecular Biology - April 23, 2024 Category: Molecular Biology Authors: Lynda Sabrina Ounaceur Mahfoud Messarah Abdelaziz Lankar Djihane Touaibia Hanene Ghadab Zohir Garri Sonia Boudjil Khadidja Belkacem Djeffel Latifa Atoui Anis Ounaceur Nesrine Djaber Amel Boumendjel Source Type: research

Cancers, Vol. 16, Pages 1611: An Overview of the Spices Used for the Prevention and Potential Treatment of Gastric Cancer
We present the potential molecular mechanisms responsible for the effectivity of a given seasoning substance and their impact on GC cells. We discuss their potential effects on proliferation, apoptosis, and migration. For most of the spices discussed, we also outline the unavailability and side effects of their use. (Source: Cancers)
Source: Cancers - April 22, 2024 Category: Cancer & Oncology Authors: Katarzyna Kostelecka Łukasz Bryliński Olga Komar Justyna Michalczyk Agata Mi łosz Jan Bi łogras Filip Woli ński Alicja Forma Jacek Baj Tags: Review Source Type: research

Oleanolic acid: an antimycobacterial component of < em > Syzygium aromaticum < /em > L. and inhibitor of efflux mediated drug resistance
Nat Prod Res. 2024 Apr 18:1-7. doi: 10.1080/14786419.2024.2343916. Online ahead of print.ABSTRACTOleanolic acid (OA) was isolated from Syzygium aromaticum L. buds, and structurally characterised using different spectroscopic techniques; MS, IR,1H/13C-NMR and 2D NMR experiments. The antimycobacterial activity according to a resazurin microtiter assay (REMA) showed important inhibitory effect of OA on the virulent H37Rv strain, with the lowest minimum concentration of 50 µg/mL, compared to other fractions. Molecular docking of OA with BacA drug efflux pump resulted in good binding affinity of hydrophobic interaction type. T...
Source: Natural Product Research - April 18, 2024 Category: Biochemistry Authors: Yassine El Ghallab Mohamed Dakir Achraf Aainouss My Driss El Messaoudi Sanae Derfoufi Source Type: research