Interventions for bullous pemphigoid
CONCLUSIONS: Clobetasol propionate cream applied over the whole body is probably similarly effective as, and may cause less mortality than, oral prednisone for treating bullous pemphigoid. Lower-dose clobetasol propionate cream applied over the whole body is probably similarly effective as standard-dose clobetasol propionate cream and has similar mortality. Doxycycline is less effective but causes less mortality than prednisolone for treating bullous pemphigoid. Other treatments need further investigation.PMID:37572360 | PMC:PMC10421473 | DOI:10.1002/14651858.CD002292.pub4 (Source: Cochrane Database of Systematic Reviews)
Source: Cochrane Database of Systematic Reviews - August 12, 2023 Category: General Medicine Authors: Sanjay Singh Gudula Kirtschig Vinayak N Anchan Ching-Chi Chi Kathy Taghipour Robert J Boyle Dedee F Murrell Source Type: research

Interventions for bullous pemphigoid
CONCLUSIONS: Clobetasol propionate cream applied over the whole body is probably similarly effective as, and may cause less mortality than, oral prednisone for treating bullous pemphigoid. Lower-dose clobetasol propionate cream applied over the whole body is probably similarly effective as standard-dose clobetasol propionate cream and has similar mortality. Doxycycline is less effective but causes less mortality than prednisolone for treating bullous pemphigoid. Other treatments need further investigation.PMID:37572360 | PMC:PMC10421473 | DOI:10.1002/14651858.CD002292.pub4 (Source: Cochrane Database of Systematic Reviews)
Source: Cochrane Database of Systematic Reviews - August 12, 2023 Category: General Medicine Authors: Sanjay Singh Gudula Kirtschig Vinayak N Anchan Ching-Chi Chi Kathy Taghipour Robert J Boyle Dedee F Murrell Source Type: research

Vulvar lichen sclerosus et atrophicus: Refractory to standard therapy
Thasneem S Luqman, Akshay Kalavant, KS Sunil Kumar, AR SwathyJournal of Indian Association of Pediatric Surgeons 2023 28(4):345-347 Vulvar lichen sclerosus et atrophicus is an inflammatory disease which can affect the pediatric age group, although rarely. Its prevalence is underestimated. It may have genital or extragenital manifestations. If left untreated, it may progress to complications which hamper the quality of life. The treatment of choice is topical clobetasol propionate. Here, we present a case of prepubertal vulvar LS, which was refractory to topical clobetasol but responded to topical tacrolimus application. (...
Source: Journal of Indian Association of Pediatric Surgeons - July 11, 2023 Category: Surgery Authors: Thasneem S Luqman Akshay Kalavant KS Sunil Kumar AR Swathy Source Type: research

CO2 LASER versus clobetasol propionate 0,05% on vulvar Lichen Sclerosus treatment for climateric women: pilot-study
Introduction: The vulvar Lichen Sclerosus (LS) is a cutaneous, inflammatory, chronic disease, of probable autoimmune etiology, that affects mainly women on climacteric. The first option of treatment is the high pontent corticosteroid (clobetasol propionate 0,05). However, the CO2 LASER is being considered as a terapeutical option. (Source: Maturitas)
Source: Maturitas - June 8, 2023 Category: Primary Care Authors: Andr éa Cytryn, Yara Lúcia Furtado, Filomena Aste Silveira, João Alfredo Seixas, Amanda Damian, Nereu Gilberto De Moraes Guerra Neto, Gutemberg Leão de Almeida Filho Tags: Abstract ID: 291 Source Type: research

Allergens in Common Brands of Clobetasol
CONCLUSIONS: Forty-nine different ingredients were identified among all 18 products included, with an average of 8.4 ingredients per product; 19 of these ingredients have allergenic potential, while one has protective effects. Two branded foam formulations contained the greatest number of potential allergens (5), while a shampoo formulation contained no potential allergens. Knowing which allergens are present in different products may be helpful when treating a patient with an allergy or suspected allergy to one of these ingredients. J Drugs Dermatol. 2023;22(5): doi:10.36849/JDD.4651.PMID:37133477 | DOI:10.36849/JDD.4651 ...
Source: Journal of Drugs in Dermatology - May 3, 2023 Category: Dermatology Authors: Leena Ramani Wasim Haidari Shalanda Hall Sima Amin Sarah Chisolm Steven Feldman Source Type: research