If a body wash falls in the forest, is it gentle on the microbiome?
Well, I guess I am happy Dove is interested in the microbiome. My exposure to Dove's thinking on the microbiome started with an ad that was shared with me by Christine Parks.The ad claims that Dove is gentle on the microbiome. OK. I am not sure I get what that means completely. But I think they are saying "Our product does not mess up your microbiome". I guess this could be good for some people if it were true. But for others, maybe you want to mess up the microbiome. Regardless, I would love to see data, if it exists, behind such a claim because my guess is that any body wash affects up the m...
Source: The Tree of Life - March 4, 2019 Category: Microbiology Authors: Jonathan Eisen Source Type: blogs

Bodily Fluids As The Basis For Digital Health
Blood, saliva, urine, sweat or even ear wax can carry valuable information about an individual’s medical state. Until now, even simpler tests on such bodily fluids had to be carried out at medical facilities, but with the recent uptick in the development of digital diagnostic technologies, more and more solutions appear on the market which enable the patient to do such tests at home. Here we take a look around the bodily fluid business. From bloodletting to digital sweat measurement Blood, yellow bile, black bile, phlegm. Although it doesn’t sound appealing, the ancient Greek already thought that bodily fluids ma...
Source: The Medical Futurist - February 27, 2019 Category: Information Technology Authors: nora Tags: Future of Medicine Health Sensors & Trackers Portable Diagnostics blood bodily fluid digital digital health digital solutions digital tattoo saliva smart smart healthcare sweat technology urine Source Type: blogs

The NextMove Patent Reaction Dataset
ConclusionOrganic synthesis underpins much of modern society. As such, it's hard to overstate the utility of an open, machine-readable, freely-reusable, annotated reaction corpus as large and complete as the NextMove reaction dataset. The theoretical and practical applications that have already appeared hint at some of the things that are now possible. (Source: Depth-First)
Source: Depth-First - January 28, 2019 Category: Chemistry Authors: Richard L. Apodaca Source Type: blogs

Acid-base and Electrolyte thoughts from Core IM Episode #14
Listening to Episode #14 of Core IM, I imagined discussing this case at VA morning report. For the past 20+ years, each month we have one session in which the chief residents present me acid-base &/or electrolyte cases to dissect. My discussion of this case is different from the podcast. That statement should not surprise anyone. This patient story lends itself to various discussions. I hope this blog post is complementary to the podcast. The presentation of quadriparesis immediately made me consider severe hypokalemia. The patient had no trauma and did not have the classic GB story. Perhaps I lean to severe hypokal...
Source: DB's Medical Rants - December 23, 2018 Category: Internal Medicine Authors: rcentor Tags: Medical Rants Source Type: blogs

Poem Sunday
ShowerI don ’t want to get out of the showerI want to stay in here where it ’s warm and wetStripped, drip drip dripped.It ’s only a thin polyvinyl chloride drapeThat hides me from that chilly lost world.I want to see you naked in the rainWhen everyone else thinks you ’ve gone insane.I want to watch you on the beachSunning yourself in rays of ruin.I want to capture you laughingAs you fall down trap doors of sorrow.Your squinting eyes are either hints of painAs you slip beyond my reach,Or the unfurling of a terminal smile.This water is warm and steady.I should like to bring you inside,Into the steam where we can hide...
Source: Buckeye Surgeon - December 2, 2018 Category: Surgery Authors: Jeffrey Parks MD FACS Source Type: blogs

Initial Evidence for the Antibiotics Azithromycin and Roxithromycin to be Senolytic
Researchers here report on two new senolytic compounds identified in the existing library of approved drugs, based on screening work in cell cultures. It is worth bearing in mind that drug candidates that demonstrate good results in cell culture quite often fail to show promise when tested in animals, so it is wise to be patient as new senolytics work their way through the research and development pipeline. There will be a lot more of this sort of thing in the years ahead, as ever greater amounts of funding pour into finding new ways to selectively destroy senescent cells. Any senolytic approach that removes a significant ...
Source: Fight Aging! - November 16, 2018 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

New At-Home Fetal Heart Rate Monitor with Clinical Accuracy
These days patients that are still in the womb have their heart rates measured on a regular basis to spot conditions such as fetal bradycardia or tachycardia or decreased variability. This is typically done in a hospital using specialty equipment that is too expensive for use in the home. Now researchers at the University of Essex in the UK have developed a new sensor that can be by the pregnant mother at home while achieving an accuracy that rivals that of in-clinic equipment. Existing fetal monitoring relies on silver chloride electrodes and ultrasound, but the U of Essex device works like an electrometer using so-call...
Source: Medgadget - October 22, 2018 Category: Medical Devices Authors: Editors Tags: Ob/Gyn Pediatrics Source Type: blogs

12 Year Old Asthmatic with Intermittent Dyspnea Unresponsive to Albuterol---What is it, and Why Now?
This case was written by one of ourgreat Hennepin 2nd year residents, Aaron Robinson, with lots of comments and edits by Smith.Thanks to Dr. Smith and Dr. Travis Olives for being part of this case. A 12 year old girl with a history of mild intermittent asthma presented to the emergency department with worsening shortness of breath over the past couple of days. She is up to date on her vaccinations and has no PMHx besides asthma and a noncontributory family history. She does not identify any specific triggers for her asthma. Initial screen in triage revealed normal vitals signs and a normal temperature. Upon interviewi...
Source: Dr. Smith's ECG Blog - August 7, 2018 Category: Cardiology Authors: Steve Smith Source Type: blogs

10 tricks to reduce salt (sodium) in your diet
The average adult eats about 3,400 milligrams (mg) of sodium per day — far more than the recommended daily goal of 2,300 mg. Here are the top 10 types of food that account for more than 40% of the sodium we eat each day, along with some ideas for simple swaps to help you eat less salt. 1. Breads and rolls This category tops the list not because bread is especially salty (a slice contains about 100 to 200 mg of sodium), but because we eat so much of it. Smart swaps: Instead of toast or a bagel for breakfast, have a bowl of oatmeal prepared with just a pinch of salt. Bypass the dinner breadbasket for a serving of whole gra...
Source: Harvard Health Blog - July 20, 2018 Category: Consumer Health News Authors: Julie Corliss Tags: Health Healthy Eating Heart Health Hypertension and Stroke Source Type: blogs

Could Have Social Media Saved Semmelweis?
Dr. Ignác Semmelweis, a Hungarian medical doctor, or ‘the savior of mothers’ suggested that hand sanitizing could save new mothers from “childbed fever”. However, the reflex reaction of his colleagues was rejection. For years, he strove for the introduction of handwashing in hospitals in vain. Being ostracized from the medical community, he died in a psychiatric ward from internal bleeding. Members of the staff beat him up. He was born 200 years ago. What if he could have shared his ideas via social media or peer-reviewed research? Could the power of online communities have saved him? The tragic fate of a doctor g...
Source: The Medical Futurist - July 14, 2018 Category: Information Technology Authors: nora Tags: Bioethics Social media in Healthcare history online community research research community Semmelweis Source Type: blogs

Citric Acid Increases Balloon Inflation (aka sour taste makes you more risky)
fromBalloon Analog Risk Task (BART)– Joggle Research for iPadRisk taking andrisk preference1 are complex constructs measured byself-report questionnaires ( “propensity”), laboratory tasks, and the frequency of real-life behaviors (smoking, alcohol use, etc).  A recent mega-study of 1507 healthy adults byFrey et al. (2017) measured risk preference using six questionnaires (and their subscales), eight behavioral tasks, and six frequency measures of real-life behavior.Table 1 (Frey et al., 2017).Risk-taking measures used in the Basel-Berlin Risk Study.-- click on image for a larger view --The authors were intereste...
Source: The Neurocritic - June 17, 2018 Category: Neuroscience Authors: The Neurocritic Source Type: blogs

Look at these " T " -waves
An alcoholic presented with confusion.  He had this ECG recorded:What do you think?Computer measures the QT at 505 ms, and QTc at 533 msThe measureappears to be correct.V3 reminds me of this ECG:Are These Wellens ' Waves??What is going on?These waves which youthink are T-wave are reallyvery large U-waves.  The clues are:1) the down-up morphology2) the apparent very long QTThe K returned at 2.1 ng/mL.The pH was 7.55 and bicarb was 47, with chloride less than 68.  The patient has a severe hypokalemic metabolic alkalosis from vomiting.(By the way, the pCO2 was 55.  An appropriate compensation for meta...
Source: Dr. Smith's ECG Blog - May 4, 2018 Category: Cardiology Authors: Steve Smith Source Type: blogs

A middle aged man with unwitnessed cardiac arrest
Written by Pendell Meyers, with edits by Steve SmithThanks to my attending Nic Thompson who superbly led this resuscitationWe received a call that a middle aged male in cardiac arrest was 5 minutes out. He was estimated to be in his 50s, with no known PMHx. He arrived with chest compressions ongoing, intubated, and being bagged. EMS report was that the patient had unknown down time with unwitnessed arrest, found initially in VFib arrest, defibrillated x1 followed by PEA arrest alternating with asystolic arrest during transport.He arrived in PEA arrest with a slow and wide cardiac waveform during initial rhythm check, with ...
Source: Dr. Smith's ECG Blog - April 6, 2018 Category: Cardiology Authors: Pendell Source Type: blogs

Fight Aging! Newsletter, April 2nd 2018
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
Source: Fight Aging! - April 1, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs