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The impact of daily supplementation with rhamnogalacturonan-I on the gut microbiota in healthy adults: A randomized controlled trial
Biomed Pharmacother. 2024 Apr 8;174:116561. doi: 10.1016/j.biopha.2024.116561. Online ahead of print.ABSTRACTPectin and its derivatives have been shown to modulate immune signaling as well as gut microbiota in preclinical studies, which may constitute the mechanisms by which supplementation of specific pectic polysaccharides confers protection against viral respiratory infections. In a double-blind, placebo-controlled rhinovirus (RV16) challenge study, healthy volunteers were randomized to consume placebo (0.0 g/day) (N = 46), low-dose (0.3 g/day) (N = 49) or high-dose (1.5 g/day) (N = 51) of carrot derived rhamnogalacturo...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - April 9, 2024 Category: Drugs & Pharmacology Authors: Ching Jian Nikolaj Sorensen Ren é Lutter Ruud Albers Willem de Vos Anne Salonen Annick Mercenier Source Type: research

Physiological and oxidative stress response of carrot (Daucus carota L.) to jumping plant-louse Bactericera trigonica Hodkinson (Hemiptera: Psylloidea) infestation
Carrot is an important vegetable crop grown worldwide. The major economic problem in carrot cultivation is yellow disease caused by Bactericera trigonica, which induces biotic stress and has the greatest impact o... (Source: BMC Plant Biology)
Source: BMC Plant Biology - April 4, 2024 Category: Biology Authors: Marija Đurić, Slađana Jevremović, Milana Trifunović-Momčilov, Snežana Milošević, Angelina Subotić and Dušanka Jerinić-Prodanović Tags: Research Source Type: research

Supramolecular Control of the Temperature Responsiveness of Fluorescent Macrocyclic Molecular Rotamers
This study provides an example of an information rich small molecule, in which programable rotational speed states can be observed with facile read-out.PMID:38499467 | DOI:10.1002/chem.202400504 (Source: Chemistry)
Source: Chemistry - March 18, 2024 Category: Chemistry Authors: Stuart N Berry Meijun Zou Sarah L Nguyen Aidan E Sajowitz Lei Qin William Lewis Katrina Jolliffe Source Type: research

Mainstreaming in parallel with ovarian cancer tumor testing to improve genetic testing uptake
CONCLUSIONS: Mainstreaming increased the likelihood of GT in patients with EOC. We found lower testing rates in patients without partners/spouses, non-high-grade serous histology, and early-stage disease, representing potential areas for future interventions.PMID:38493020 | DOI:10.1016/j.ygyno.2024.03.005 (Source: Gynecologic Oncology)
Source: Gynecologic Oncology - March 16, 2024 Category: Cancer & Oncology Authors: Maureen Byrne Tiffany Y Sia Christopher Fong Aliya Khurram Michele Waters Yelena M Kemel Qin Zhou Megha Ranganathan Kara Long Roche Dennis S Chi Sally Saban Michelle Wu Nancy Varice Jada G Hamilton Jian Carrot-Zhang Nadeem R Abu-Rustum Alexia Iasonos Lora Source Type: research

Molecules, Vol. 29, Pages 1259: High-Pressure Processing of Fruit Smoothies Enriched with Dietary Fiber from Carrot Discards: Effects on the Contents and Bioaccessibilities of Carotenoids and Vitamin E
r Böhm The effects of high-pressure processing (HPP) (450 MPa/600 MPa/3 min) on the carotenoid and vitamin E contents of smoothies made from strawberry, orange juice, banana and apple, and the same smoothies enriched with dietary fiber from discarded carrots were compared. The contents and bioaccessibilities of these compounds were also evaluated over the course of 28 days at 4 &deg;C. The application of HPP in the formulations significantly increased the contents of &beta;-cryptoxanthin, &alpha;-carotene and &beta;-carotene and retained the contents of lutein, zeaxanthin and vitamin E ...
Source: Molecules - March 12, 2024 Category: Chemistry Authors: Melisa Donda Zbinden Mario Schmidt Charito Ivana Vignatti Mar ía Élida Pirovani Volker B öhm Tags: Article Source Type: research

Genome-wide analysis of plant specific YABBY transcription factor gene family in carrot (Dacus carota) and its comparison with Arabidopsis
YABBY gene family is a plant-specific transcription factor with DNA binding domain involved in various functions i.e. regulation of style, length of flowers, and polarity development of lateral organs in floweri... (Source: BMC Genetics)
Source: BMC Genetics - March 5, 2024 Category: Genetics & Stem Cells Authors: Mujahid Hussain, Muhammad Mubashar Javed, Adnan Sami, Muhammad Shafiq, Qurban Ali, Hafiz Sabah-Ud-Din Mazhar, Javaria Tabassum, Muhammad Arshad Javed, Muhammad Zeeshan Haider, Muhammad Hussain, Irfan Ali Sabir and Daoud Ali Tags: Research Source Type: research

Molecules, Vol. 29, Pages 1093: Effects and Mechanisms of Luteolin, a Plant-Based Flavonoid, in the Prevention of Cancers via Modulation of Inflammation and Cell Signaling Molecules
n Rahmani Luteolin, a flavonoid, is mainly found in various vegetables and fruits, including carrots, cabbages, onions, parsley, apples, broccoli, and peppers. Extensive research in vivo and in vitro has been performed to explore its role in disease prevention and treatment. Moreover, this compound possesses the ability to combat cancer by modulating cell-signaling pathways across various types of cancer. The studies have confirmed that luteolin can inhibit cancer-cell survival and proliferation, angiogenesis, invasion, metastasis, mTOR/PI3K/Akt, STAT3, Wnt/&beta;-catenin, and cell-cycle arrest, and induce apop...
Source: Molecules - February 29, 2024 Category: Chemistry Authors: Saleh A. Almatroodi Ahmad Almatroudi Hajed Obaid A. Alharbi Amjad Ali Khan Arshad Husain Rahmani Tags: Review Source Type: research

Formulation of Functional Liquid Diets Under IDDSI Levels 0 to 2 for Dysphagia Patients: Physico-Chemical, Sensory, Antioxidant and Electromyographic Oral Processing Analyses
In this study, functional liquid diets were formulated under International Dysphagia Diet Standardization Initiative (IDDSI) levels 0 –2. The developed diets were analysed for their proximate composition, colour, antioxidant and sensory properties. Antioxidant activities were determined using 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS+), 2,2-diphenyl-1-picrylhydrazyl (DPPH), ferric reducing antioxidant power (FRAP) and total phenolic content (TPC) methods. The highest ABTS+ value was observed in pumpkin puree (level-2) i.e. 98.59%. Black carrot juice (level-1) showed the highest DPPH free radical scav...
Source: Dysphagia - February 21, 2024 Category: Speech-Language Pathology Source Type: research

Molecules, Vol. 29, Pages 917: Bioactive Potential of Carrot-Based Products Enriched with Lactobacillus plantarum
rămioara Lisă The primary goal of this study was to generate different kinds of functional products based on carrots that were supplemented with lactic acid bacteria. The fact that carrots (Daucus carota sp.) rank among the most popular vegetables in our country led to the convergence of the research aim. Their abundance of bioactive compounds, primarily polyphenols, flavonoids, and carotenoids, offers numerous health benefits. Among the obtained products, the freeze-dried carrot powder (FDCP) variation presented the highest concentrations of total carotenoids (TCs) and &beta;-carotene (BC) of 26.977 &amp...
Source: Molecules - February 19, 2024 Category: Chemistry Authors: Monica Boev Cristina St ănescu Mihaela Turturic ă Mihaela Cot ârleţ Denisa Bat îr-Marin Nicoleta Maftei Carmen Chi ţescu Leontina Grigore-Gurgu Vasilica Barbu Elena Enachi Elena L ăcrămioara Lisă Tags: Article Source Type: research

Prognostic Value of the Modeled Prostate-Specific Antigen KELIM Confirmation in Metastatic Castration-Resistant Prostate Cancer Treated With Taxanes in FIRSTANA
CONCLUSION: This external validation study confirmed previous results about modeled PSA longitudinal kinetics prognostic value regarding PFS/OS in patients with mCRPC treated with taxanes. PSA.KELIM could be used to identify a subpopulation with poor prognosis, who may benefit from treatment intensification.PMID:38364191 | DOI:10.1200/CCI.23.00208 (Source: Clinical Prostate Cancer)
Source: Clinical Prostate Cancer - February 16, 2024 Category: Cancer & Oncology Authors: Aurore Carrot St éphane Oudard Olivier Colomban Karim Fizazi Denis Maillet Oliver Sartor Gilles Freyer Benoit You Source Type: research

Description of Microbacterium dauci sp. nov., a plant growth hormone indoleacetic acid-producing and nitrogen-fixing bacterium isolated from carrot rhizosphere soil
Arch Microbiol. 2024 Feb 14;206(3):102. doi: 10.1007/s00203-023-03810-7.ABSTRACTA plant growth hormone indoleacetic acid-producing strain LX3-4T was isolated from a carrot rhizosphere soil sample collected in Shandong Province, China. It is Gram-stain-positive, non-motile, and has irregular short rod-shaped cells. LX3-4T shared high 16S rRNA gene sequence identity with Microbacterium oleivorans DSM 16091T (99.4%), M. testaceum NBRC 12675T (98.6%), M. marinum DSM 24947T (98.5%), M. resistens NBRC 103078T (98.4%), and M. paraoxydans NBRC 103076T (98.3%). Phylogenetic analysis based on the concatenated gene sequences of 16S r...
Source: Archives of Microbiology - February 14, 2024 Category: Microbiology Authors: Jiawen Zheng Yunyu Liao Yang Li Dongsheng Li Yaping Sun Zijun Xiao Source Type: research