Understanding Neurological Effects of COVID-19 and Post-Acute Sequelae of SARS-CoV-2 Infection (R01 Clinical Trial Optional)
Funding Opportunity RFA-NS-23-021 from the NIH Guide for Grants and Contracts. The purpose of thisNotice of Funding Opportunity (NOFO)is to invite applicationsfocused on theneurological and neuropsychiatric manifestationsof COVID-19 (neuro-COVID) andPost-Acute Sequelae of SARS-CoV-2 Infection (neuro-PASC) and on the effect of COVID-19 on pre-infection neurologic conditions. Applications investigating the pathophysiology and mechanisms of neuro-COVID and neuro-PASC and neurologically-focused human subjects research, as well as those proposing studies of scientifically compelling pathways to prevent the development of neu...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 28, 2023 Category: Research Source Type: funding
Notice of Special Interest of NCCIH in PAR-22-097/098, "Global Brain and Nervous System Disorders Research Across the Lifespan (R01/R21 Clinical Trial Optional)
Notice NOT-AT-24-001 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 27, 2023 Category: Research Source Type: funding
Novel Approaches for Developmental Neurotoxicity Testing (R43/R44 Clinical Trial Not Allowed)
Funding Opportunity RFA-ES-23-008 from the NIH Guide for Grants and Contracts. This Notice of Funding Opportunity (NOFO) supports Phase I (R43), Phase II (R44), Direct to Phase II (R44), and Fast Track (R44) Small Business Innovative Research (SBIR) grant applications from small businesses concerns (SBCs) to develop resources, new methods, and approaches that can be applied in testing strategies to help understand the role of environmental chemicals in the etiology of the neurodevelopmental disorders. There is a need for novel and innovative approaches including New Approach Methodologies (NAMs) that can provide effecti...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 21, 2023 Category: Research Source Type: funding
Jointly Sponsored Ruth L. Kirschstein National Research Service Award Institutional Predoctoral Training Program in the Neurosciences (T32 Clinical Trial Not Allowed)
Funding Opportunity PAR-22-265 from the NIH Guide for Grants and Contracts. Reissue of PAR-17-096. The Jointly Sponsored NIH Predoctoral Training Program in the Neurosciences (JSPTPN) is an institutional program that supports broad and fundamental research training in the neurosciences. In addition to a broad education in the neurosciences, a key component will be a curriculum that provides a strong foundation in experimental design, statistical methodology and quantitative reasoning. JSPTPN programs are intended to be 2 years in duration and students may only be appointed to this training grant during the first 2 years...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 20, 2023 Category: Research Source Type: funding
NINDS Institutional AD/ADRD Research Training Program (T32 Clinical Trial Not Allowed)
Funding Opportunity PAR-23-113 from the NIH Guide for Grants and Contracts. The purpose of this FOA is to provide support for institutional research training programs in Alzheimers Disease/Alzheimers Disease-Related Dementias (AD/ADRD). These institutional research training programs should produce well-trained neuroscientists who leave the program with the research skills and scientific knowledge to make a significant contribution to research on AD/ADRD cognitive impairment and dementia. Programs should be designed to enhance the breadth and depth of training across the spectrum AD/ADRD research areas (e.g. AD, Vascular...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 20, 2023 Category: Research Source Type: funding
Notice of Intent to Publish a Funding Opportunity for Emergency Medicine Research Career Development Program in the Neurological Sciences (EMRCDP-NS) (K12 - No Independent Clinical Trial Allowed)
Notice NOT-NS-23-065 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 16, 2023 Category: Research Source Type: funding
Limited Competition: The Health and Retirement Study and Harmonized Cognitive Assessment Protocol (U01 Clinical Trial Not Allowed)
Funding Opportunity RFA-AG-24-010 from the NIH Guide for Grants and Contracts. The purpose of this limited competition FOA is to solicit an application to continue data collection, development, and dissemination of the Health and Retirement Study (HRS). The HRS is a longitudinal panel study that surveys a nationally representative sample of approximately 20,000 people aged 50 and older in the United States via mixed-mode data collection to support multidisciplinary research on life course health and aging. This renewal provides additional research opportunities to use HRS to study Alzheimers Disease and Related Dementia...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 14, 2023 Category: Research Source Type: funding
BRAIN Initiative: New Technologies and Novel Approaches for Recording and Modulation in the Nervous System (R01 Clinical Trial Not Allowed)
Funding Opportunity RFA-NS-24-004 from the NIH Guide for Grants and Contracts. Reissue of RFA-NS-18-020: Understanding the dynamic activity of brain circuits is central to the NIH BRAIN Initiative. This FOA seeks applications for proof-of-concept testing and development of new technologies and novel approaches for recording and modulation (including various modalities for stimulation/activation, inhibition and manipulation) of cells (i.e., neuronal and non-neuronal) and networks to enable transformative understanding of dynamic signaling in the central nervous system (CNS). This FOA seeks exceptionally creative approach...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 14, 2023 Category: Research Source Type: funding
BRAIN Initiative: Optimization of Instrumentation and Device Technologies for Recording and Modulation in the Nervous System (U01 Clinical Trials Not Allowed)
Funding Opportunity RFA-NS-24-005 from the NIH Guide for Grants and Contracts. Reissue of RFA-NS-18-019: Understanding the dynamic activity of neural circuits is central to the NIH BRAIN Initiative. The invention, proof-of-concept investigation, and optimization of new technologies through iterative feedback from end users are key components of the BRAIN Initiative. This FOA seeks applications to optimize existing or emerging technologies through iterative testing with end users. The technologies and approaches should have potential to address major challenges associated with recording and modulation (including various ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 14, 2023 Category: Research Source Type: funding
Blood Brain Barrier Response to Antibodies Targeting Beta-Amyloid (R01 - Clinical Trial Not Allowed)
Funding Opportunity PAR-23-140 from the NIH Guide for Grants and Contracts. This initiative is designed to promote discovery of cellular and molecular mechanisms that underlie brain blood vessels responses to passive anti-beta-amyloid immunotherapy that result in amyloid-related imaging abnormalities (ARIA). The goal is to establish an understanding of molecular mechanisms that can be targeted to protect the blood brain barrier (BBB), and thus the brain blood vessels, during therapeutic interventions that target beta-amyloid. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 14, 2023 Category: Research Source Type: funding
Ex Vivo Models for Studies at the Intersection of HIV and Poly-Substance Use (R01 Clinical Trial Not Allowed)
Funding Opportunity RFA-DA-24-001 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites grant applications aimed at elucidating neuroimmune and neuronal-glial pathophysiological mechanisms of HIV-associated neurological disorders (HAND) using ex vivo culturing platforms derived from human induced pluripotent stem cells (hiPSC) in the presence of addictive substances. Specific emphasis is on unbiased, reproducible analysis of genetics and epigenetics, neuroglial interactions, and neuroimmune cell activities from the single cell to neural circuit levels. (Source: NIH Funding Oppo...
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 28, 2023 Category: Research Source Type: funding
Notice of Intent to Publish a Funding Opportunity Announcement for Understanding Neurological Effects of COVID-19 and Post-Acute Sequelae of SARS-CoV-2 Infection (R01 Clinical Trial Optional)
Notice NOT-NS-23-068 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 23, 2023 Category: Research Source Type: funding
Notice of Intent to Publish a Funding Opportunity Announcement for Understanding Neurological Effects of COVID-19 and Post-Acute Sequelae of SARS-CoV-2 Infection (R21 Clinical Trial Optional)
Notice NOT-NS-23-069 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 23, 2023 Category: Research Source Type: funding
Take Advantage of Our Many Resources for Enhancing the Rigor of Animal Research
“Despite the numerous successes stemming from animal research, concerning reports over the past decade have described biomedical experiments that fail to replicate or to translate in ways that improve human health. All research is not expected to translate to human treatments, as there is no perfect model. Scientific process is as much about failure as it is about success. Yet part of the scientific process is also continual improvement, which includes working to understand what might contribute to unexpected outcomes within animal research.”
The Advisory Committee to the NIH Director (ACD) expressed that view in their...
Source: NIH Extramural Nexus - February 10, 2023 Category: Research Authors: Mike Lauer Tags: blog Open Mike Alternatives to Animals reproducibility rigor Source Type: funding
Using Multimodal Biomarkers to Differentially Diagnose ADRDs for Clinical Trials (U19 Clinical Trial Optional)
Funding Opportunity RFA-NS-24-001 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity is to enable multi-site clinical validation of a multimodal set of neuroimaging and biospecimen biomarkers to differentially diagnosis three or more similarly presenting neurodegenerative diseases, including at least one of the Alzheimers Disease and Related Dementias (ADRDs). As part of the program deliverables, investigators will be required to work towards qualifying the candidate biomarkers as therapeutic/drug development tools through the FDAs Biomarker Qualification Program. *Note this FOA has cha...
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 9, 2023 Category: Research Source Type: funding
