Investigating the Effects of Addictive Substances on Brain Developmental Trajectories Using Innovative Scalable Methods for Quantification of Cell Identity, Lineage and Connectivity (R01 - Clinical Trial Not Allowed)
Funding Opportunity RFA-DA-23-036 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) will support projects that investigate the effects of addictive substances on developmental trajectories of molecularly-defined CNS cells and circuits. Emphasis is on carrying out systematic and highly granular quantitative characterizations of the impact of in utero and/or postnatal substance exposure on the numbers, spatial distribution and connectivity of molecularly-defined cells, across whole brains or within distributed circuits of clinical relevance. The ultimate goals of the program are to i...
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 8, 2022 Category: Research Source Type: funding

Targeting Inflammasomes in Substance Abuse and HIV (R21 Clinical Trial Not Allowed)
Funding Opportunity RFA-DA-24-004 from the NIH Guide for Grants and Contracts. The scientific objective of this Funding Opportunity Announcement is to encourage research to delineate the role of inflammasomes in the neuropathology produced by acute or chronic drug exposure and HIV infection. Understanding the involvement of inflammasomes in virus and drug-induced immune activation may help identify molecular markers and CNS immune cells associated with HIV-1 infection or disease progression among substance abuse populations, as well as identify novel therapies to target inflammasome activation or suppression to treat ne...
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 3, 2022 Category: Research Source Type: funding

Targeting Inflammasomes in Substance Abuse and HIV (R01 Clinical Trial Not Allowed)
Funding Opportunity RFA-DA-24-003 from the NIH Guide for Grants and Contracts. The scientific objective of this Funding Opportunity Announcement is to encourage research to delineate the role of inflammasomes in the neuropathology produced by acute or chronic drug exposure and HIV infection. Understanding the involvement of inflammasomes in virus and drug-induced immune activation may help identify molecular markers and CNS immune cells associated with HIV-1 infection or disease progression among substance abuse populations, as well as identify novel therapies to target inflammasome activation or suppression to treat ne...
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 3, 2022 Category: Research Source Type: funding

Notice of Pre-Application Technical Assistance Webinar for RFA-DA-23-030, "BRAIN Initiative: Brain-Behavior Quantification and Synchronization Transformative and Integrative Models of Behavior at the Organismal Level (R34 Clinical Trial Not Allowed)"
Notice NOT-DA-22-083 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 2, 2022 Category: Research Source Type: funding

Functional Validation and/or Characterization of Genes or Variants Implicated in Substance Use Disorders (R21/R33 Clinical Trial Not Allowed)
Funding Opportunity PAR-23-041 from the NIH Guide for Grants and Contracts. The purpose of this initiative is to support projects which exploit genome or epigenome editing to functionally validate and characterize genes or variants involved in substance use disorder-relevant phenotypes. It is expected that any genetic resources generated will be made broadly available to the scientific community to enable investigation of the relevant neurobiological mechanisms involved and provide critical foundational knowledge for the development of future prevention, diagnostic, and therapeutic strategies. (Source: NIH Funding Oppor...
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 1, 2022 Category: Research Source Type: funding