Notice of Special Interest (NOSI): Availability of Administrative Supplements for BRAIN Initiative Recipients to Support Resource Dissemination
Notice NOT-EB-23-010 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - August 16, 2023 Category: Research Source Type: funding

Addressing Rigor in Scientific Studies
Guest blog by Devon C. Crawford, Ph.D., Program Director, Office of Research Quality, NIH’s National Institute of Neurological Disorders and Stroke. Originally published on the NIH Science, Health, and Public Trust blog. Devon C. Crawford, Ph.D., Program Director, Office of Research Quality Science communication is rapidly evolving. The growing use of preprints and the sheer number of published studies make it increasingly difficult to determine which findings are worthy of attention. Not all scientific studies are created equal. Communicators need to discern which are reputable in order to know what to co...
Source: NIH Extramural Nexus - August 14, 2023 Category: Research Authors: NIH Staff Tags: blog Open Mike Grants policy rigor Source Type: funding

Neural and Non-Neural Mechanisms Underlying Gait as a Preclinical Marker for Alzheimers Disease and Alzheimers Disease-Related Dementias (R01 Clinical Trial Optional)
Funding Opportunity RFA-AG-24-041 from the NIH Guide for Grants and Contracts. The purpose of this Notice of Funding Opportunity (NOFO) is to invite applications that investigate the neural and/or non-neural mechanisms that underlie the association between gait and cognition in aging and Alzheimer's disease and Alzheimer's disease-related dementias (AD/ADRD). Elucidating these mechanisms would help inform the potential use of changes gait as an early biomarker of AD/ADRD or inform the design of early interventions for AD/ADRD. To achieve these goals, it will be necessary to facilitate a team science approach by bringing...
Source: NIH Funding Opportunities (Notices, PA, RFA) - August 11, 2023 Category: Research Source Type: funding

NIH Brain Development Cohorts (NBDC) Biospecimen Access (X01 Clinical Trial Not Allowed)
Funding Opportunity PAR-23-229 from the NIH Guide for Grants and Contracts. The Adolescent Brain Cognitive Development (ABCD) Study is the largest longitudinal study of brain development and child health collecting data from more than 11,000 children across the U.S. beginning when they are 9-10 years old and continuing for a decade. In addition to behavioral assessments, youth undergo neuroimaging and provide biospecimens, including saliva for hormone analysis, urine and hair for substance use and exposure, deciduous teeth for environmental exposure, and blood for genetic analysis and metabolic and hematologic assays. T...
Source: NIH Funding Opportunities (Notices, PA, RFA) - August 11, 2023 Category: Research Source Type: funding

Community-Engaged Health Equity Research in Neuroscience Initiative (R34 CT Not Allowed)
Funding Opportunity RFA-NS-24-007 from the NIH Guide for Grants and Contracts. This NOFO solicits applications for planning grants to assess feasibility and/or determine best practices to conduct community-engaged health equity research in neurological disorders with populations that experience health disparities (HDPs). If successful, these planning grants would support, enable and/or lay the groundwork for future clinical studies or trials.In addition to posing a research question related to addressing health disparities in neurological disorders, applicants must also be filling a gap in 1) Engagement with one or more...
Source: NIH Funding Opportunities (Notices, PA, RFA) - August 11, 2023 Category: Research Source Type: funding

Community-Engaged Health Equity Research in Neuroscience Initiative (R01 CT Not Allowed)
Funding Opportunity RFA-NS-24-006 from the NIH Guide for Grants and Contracts. TBD (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - August 10, 2023 Category: Research Source Type: funding

Notice of Early Termination of PAR-21-059 "Clinical Validation of a Candidate Biomarker for Neurological or Neuromuscular Disorders (U44 Clinical Trial Optional)"
Notice NOT-NS-23-104 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - August 8, 2023 Category: Research Source Type: funding

Notice of Early Termination of PAR-21-057 "Analytical Validation of a Candidate Biomarker for Neurological or Neuromuscular Disorders (U44 Clinical Trial Optional)"
Notice NOT-NS-23-103 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - August 8, 2023 Category: Research Source Type: funding

Feasibility Trials of the NIH Music-based Interventions Toolkit for Brain Disorders of Aging (R34 Clinical Trial Required)
Funding Opportunity PAR-23-256 from the NIH Guide for Grants and Contracts. The purpose of this Notice of Funding Opportunity (NOFO) is to support proof-of-concept feasibility trials guided by the NIH Music-based Interventions (MBI) Toolkit for research on brain disorders of aging. These early phase clinical trials will generate evidence supporting the validity of the NIH MBI Toolkits guiding principles as well as the necessary pilot data to design a subsequent clinical efficacy or effectiveness study (or pragmatic clinical trial) using music-based interventions in the context of brain disorders of aging, including but ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - August 7, 2023 Category: Research Source Type: funding

Alcohol and Other Substance Use Research Education Programs for Health Professionals (R25 Clinical Trial Not Allowed)
Funding Opportunity PAR-23-240 from the NIH Guide for Grants and Contracts. The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The over-arching goal of this NIAAA/NIDA R25 program is to support educational activities that foster a better understanding of biomedical, behavioral, and clinical research on alcohol and other substance use disorders and their implications. To accomplish the stated over-arching goal, this FOA will support creative educational activities with a primary focus on Outreach. Specifically, this FOA will support projects designed to engage...
Source: NIH Funding Opportunities (Notices, PA, RFA) - August 1, 2023 Category: Research Source Type: funding

A Consortium for Gut-Brain Communication in Parkinsons Disease (U24 Clinical Trial not allowed)
Funding Opportunity RFA-DK-23-001 from the NIH Guide for Grants and Contracts. Parkinsons disease (PD) is the second most common and fastest growing neurodegenerative disorder, with approximately 60,000 Americans diagnosed annually. PD symptoms are not limited to motor dysfunction and more than 50% of patients who develop PD often have a history of bowel complaints affecting nearly all parts of the gastrointestinal (GI) system. These SI symptoms often precede the onset of motor symptoms, indicating that GI dysfunction may be an early manifestation of the disease and the gut may be an unexplored diagnostic and/or therape...
Source: NIH Funding Opportunities (Notices, PA, RFA) - July 31, 2023 Category: Research Source Type: funding

A Consortium for Gut-Brain Communication in Parkinsons Disease (U01 Clinical Trial Not Allowed)
The objective of this consortium is to accelerate research on the role gastrointestinal (GI) symptoms and changes in gut-brain communication in the initiation and pathogenesis of Parkinsons disease in order to facilitate development and validation of innovative early-phase GI-based diagnostic tools and biomarkers for PD. The research centers of the GBPDC will serve as sites for enrollment of PD patients with and without GI symptoms, patients with GI symptoms considered to be at risk for PD, and healthy age-matched controls for laboratory-based studies on biological samples obtained from these patients. The NIDDK strongly e...
Source: NIH Funding Opportunities (Notices, PA, RFA) - July 31, 2023 Category: Research Source Type: funding

Notice of Special Interest (NOSI): BRAIN Initiative: Mentored Clinician Scientist Research Career Development program to Develop Expertise in Intracranial Human Neuroscience Research (K08)
Notice NOT-AA-23-015 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - July 26, 2023 Category: Research Source Type: funding

NIH Blueprint and BRAIN Initiative Program for Enhancing Neuroscience Diversity through Undergraduate Research Education Experiences (BP BRAIN-ENDURE) (R25 Clinical Trial Not Allowed)
Funding Opportunity RFA-NS-24-014 from the NIH Guide for Grants and Contracts. The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The over-arching goal of this NIH Blueprint R25 program is to encourage individuals from diverse backgrounds, including those from groups underrepresented in the biomedical, behavioral, and clinical research workforce, to pursue further studies or careers in research. To accomplish the stated over-arching goal, this FOA will support creative educational activities with a primary focus on Courses for Skills Development, Research E...
Source: NIH Funding Opportunities (Notices, PA, RFA) - July 21, 2023 Category: Research Source Type: funding

The Role of Sleep Deficiency in Persons with Type 1 Diabetes: Sleep, Glycemic Control, and Cardiovascular Risk (R34 Clinical Trial Optional)
Funding Opportunity RFA-HL-24-009 from the NIH Guide for Grants and Contracts. This NOFO will support preliminary studies aimed to obtain information necessary to guide the design of a full randomized control trial to test whether sleep and circadian targeted interventions improve the clinical course and treatment outcomes in individuals with Type 1 Diabetes (T1D). Applications should focus on pilot studies to inform practical and potentially sustainable strategies to improve processes of care and cardiometabolic health outcomes in individuals with T1D. The scope of research for this NOFO includes a range of feasibility...
Source: NIH Funding Opportunities (Notices, PA, RFA) - July 20, 2023 Category: Research Source Type: funding