BRAIN Initiative: Preclinical Proof of Concept for Novel Recording and Modulation Technologies in the Human CNS (R18 - Clinical Trial Not Allowed)
Funding Opportunity RFA-NS-24-031 from the NIH Guide for Grants and Contracts. Awarded activities will facilitate the translation of novel recording and modulation technologies that can be used to treat and/or diagnose central nervous system (CNS) diseases and disorders and to better understand the human CNS, from proof of concept up to the stage of readiness for first in human (FIH) studies. Technologies may incorporate any signal modality (e.g., electrical, optical, magnetic, acoustic) or a combination thereof. Diverse team-based applications that integrate appropriate domains of expertise are encouraged. (Source: NIH...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 19, 2024 Category: Research Source Type: funding

BRAIN Initiative: Data Archives for the BRAIN Initiative (R24 Clinical Trial Optional)
Funding Opportunity RFA-MH-25-110 from the NIH Guide for Grants and Contracts. This Notice of Funding Opportunity (NOFO) solicits applications to develop web-accessible data archives to capture, store, and curate data related to BRAIN Initiative activities. The data archives will work with the research community to incorporate tools that allow users to analyze and visualize the data, but the creation of such tools is not part of this NOFO. The data archives will use appropriate standards to describe the data, but the creation of such standards is not part of this NOFO. A goal of this program is to advance research by cr...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 19, 2024 Category: Research Source Type: funding

BRAIN Initiative: Clinical Studies to Advance Next-Generation Devices for Recording and Modulation in the Human Central Nervous System (UH3 Clinical Trial Optional)
Funding Opportunity RFA-NS-24-017 from the NIH Guide for Grants and Contracts. Reissue: RFA-NS-21-024: The purpose of this Funding Opportunity Announcement (FOA) is to encourage investigators to pursue a small clinical trial to obtain critical information necessary to advance recording and/or stimulating devices to treat central nervous system disorders and better understand the human brain (e.g., Early Feasibility Study). Clinical studies supported may consist of acute or short-term procedures that are deemed Non-Significant Risk (NSR) by an Institutional Review Board (IRB), or Significant Risk (SR) studies that requir...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 19, 2024 Category: Research Source Type: funding

Research on the Neuro-Immune Axis in the Context of HIV and Substance Use (R21 Clinical Trial Not Allowed)
Funding Opportunity RFA-DA-25-005 from the NIH Guide for Grants and Contracts. The purpose of this notice of funding opportunity (NOFO) is to support research towards identifying and characterizing neuroimmune networks, communication pathways, and targets that reside within neuroimmune axes, in the context of HIV and substance use. This NOFO will also support research on the discovery of novel modulatory probes/tools that can advance our knowledge of the regulatory mechanisms by which neuroimmune interactions contribute to HIV and substance use disorder comorbidity. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 14, 2024 Category: Research Source Type: funding

Research on the Neuro-Immune Axis in the context of HIV and Substance Use (R01 Clinical Trial Not Allowed)
Funding Opportunity RFA-DA-25-004 from the NIH Guide for Grants and Contracts. The purpose of this notice of funding opportunity (NOFO) is to support research towards identifying and characterizing neuroimmune networks, communication pathways, and targets that reside within neuroimmune axes, in the context of HIV and substance use. This NOFO will also support research on the discovery of novel modulatory probes/tools that can advance our understanding of the regulatory mechanisms by which neuroimmune interactions contribute to HIV and substance use disorder comorbidity. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 14, 2024 Category: Research Source Type: funding

Exploring Proteogenomic Approaches to Unravel the Mechanisms of Mis-Folded Protein Accumulation in Tauopathies (R01 Clinical Trial Not Allowed)
Funding Opportunity RFA-AG-25-017 from the NIH Guide for Grants and Contracts. This funding opportunity invites innovative research proposals to explore the accumulation of misprocessed proteins in Tauopathies within specific brain regions and cell types. We encourage collaborative efforts to create advanced single-cell or single-cell type proteogenomic platforms. These platforms aim to shed light on dynamic changes in protein-misfolding responses in neuronal proteomes and their potential biological consequences during aging and the development of AD and ADRD. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 13, 2024 Category: Research Source Type: funding

NINDS Advanced Institutional Research Training Program (T32 Clinical Trial Not Allowed)
Funding Opportunity PAR-24-126 from the NIH Guide for Grants and Contracts. The purpose of this FOA is to provide support for institutional research training programs in areas relevant to the NINDS mission. These institutional research training programs should produce well-trained neuroscientists who leave the program with the research skills and scientific knowledge to make a significant contribution to neuroscience research. Programs should be designed to enhance the breadth and depth of training in NINDS mission areas by incorporating didactic, research and career development components in the context of a defined sc...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 12, 2024 Category: Research Source Type: funding

Notice of Change to RFA-MH-254-171, "BRAIN Initiative: Research on the Ethical Implications of Advancements in Neurotechnology and Brain Science (R21 Clinical Trial Optional"
Notice NOT-MH-24-205 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 1, 2024 Category: Research Source Type: funding

Institutional Translational Research Training Program (T32 - Clinical Trial Not Allowed)
Funding Opportunity PAR-24-108 from the NIH Guide for Grants and Contracts. The purpose of the NINDS Institutional Translational Research Training Program is to equip trainees with the knowledge and skills needed to advance basic research toward clinical application. These programs will support, students and/or postdocs conducting basic, disease-relevant research in an environment that includes 1) basic neuroscientists and clinicians who are actively engaged in collaborative research projects, 2) neuroscience researchers with expertise in translational processes who are conducting research designed to move basic discove...
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 28, 2024 Category: Research Source Type: funding

Notice of Intent to Publish a Funding Opportunity Announcement for Novel Preclinical Models of NeuroHIV in the cART Era (R61/R33 - Clinical Trial Not Allowed)
Notice NOT-NS-24-065 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 27, 2024 Category: Research Source Type: funding

Notice of Special Interest (NOSI): Myelin plasticity in sculping addiction neurocircuitry
Notice NOT-DA-25-028 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 26, 2024 Category: Research Source Type: funding

NIH All About Grants Podcast: Ins and Outs of Training Grants (miniseries)
Dr. Maria Carranza, Senior Training Officer with the National Institute on Aging Dr. Kenneth Gibbs, Chief of the Undergraduate and Predoctoral Cross-Disciplinary Training Branch at the National Institute of General Medical Sciences Institutional training grants help prepare undergraduates, predoctoral students and postdoctoral scholars for careers in biomedical and behavioral research. Part 1 of this NIH All About Grants podcast miniseries dives into considerations for developing training grant applications and the review process, and part 2 focuses on post-award monitoring, mentorship, and provides insights for traine...
Source: NIH Extramural Nexus - February 26, 2024 Category: Research Authors: NIH Staff Tags: New Resources mentorship trainees training grants workforce Source Type: funding

Translational Neural Devices (R61/R33 - Clinical Trial Optional)
Funding Opportunity PAR-24-151 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to encourage investigators to pursue translational activities and small clinical studies to advance the development of therapeutic, and diagnostic devices for disorders that affect the nervous or neuromuscular systems. Activities supported in this program include implementation of clinical prototype devices, non-clinical safety and efficacy testing, design verification and validation activities, obtaining an Investigational Device Exemption (IDE) for a Significant Risk (SR) study or I...
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 23, 2024 Category: Research Source Type: funding

INCLUDE (INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE) Predoctoral to Postdoctoral Fellow Transition Award (F99/K00 Clinical Trial Not Allowed)
Funding Opportunity RFA-OD-24-007 from the NIH Guide for Grants and Contracts. The purpose of the INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Predoctoral to postdoctoral Fellow Transition award (F99/K00) is to recruit exceptional graduate students from diverse research fields to pursue postdoctoral training focused on Down syndrome related research. Talented graduate students from disciplines including, but not limited to, genetics, biochemistry, data science, imaging, engineering and neurobiology are invited to apply to this opportunity. Prospective applicants are ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 22, 2024 Category: Research Source Type: funding

Notice of NICHD Withdrawal from Participation in PAR-24-063 " Blueprint Neurotherapeutics Network (BPN): Small Molecule Drug Discovery and Development for Disorders of the Nervous System (U44 Clinical Trial Optional)
Notice NOT-HD-24-006 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 22, 2024 Category: Research Source Type: funding