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8 Rare 'House, M.D.' Cases That Can Actually Happen (And How To Avoid Them)
"House, M.D.," starring Hugh Laurie as a pill-popping genius, was conceived as the medical version of "Sherlock Holmes" and ran for eight seasons on Fox. Sunday, Nov. 16, marked the 10-year anniversary of the premiere. Though it's easy to look back on the show and focus on some of the unbelievable details of the cases, it might surprise you to learn that "House" was actually much more realistic than you thought. Yeah, the odds of all these rare medical cases coming to one hospital in New Jersey are pretty slim, but a variety of sources -- including Andrew Holtz, former CNN Medical Correspondent and author of Medical Scien...
Source: Science - The Huffington Post - November 17, 2014 Category: Science Source Type: news

Overcoming Cancer Consent
Part I: Non-Consensual Cancer Growing up, one of my heroes was Sir Ernest Shackleton. He was a polar explorer at the turn of the century who led an expedition straight south to explore Antarctica in his ship, aptly named The Endurance, with a motley crew of burly Englishmen wrapped in layers of wool, icicles hanging from their thick beards. After their ship was stuck in ice and capsized, Shackleton had to abandon his exploration mission and lead his crew through the harsh Antarctic conditions to safety. To his men, Shackleton was a true leader, heroic, humble and selfless. I have not thought much about Shackleton since t...
Source: Healthy Living - The Huffington Post - October 31, 2014 Category: Consumer Health News Source Type: news

Bone marrow drug could treat alopecia
Conclusion This is valuable laboratory research that identifies the specific type of immune cell (CD8+NKG2D+ T cells) that is involved in the disease process of alopecia. It further identifies several signalling molecules that are drivers of this T cell activity. The researchers then demonstrate that giving two molecular treatments to block the signalling molecules – ruxolitinib (currently licensed in the UK to treat certain bone marrow disorders) and tofacitinib (not currently licensed for any condition in the UK) – were effective in preventing and reversing the disease process in mice with alopecia. These findings i...
Source: NHS News Feed - August 18, 2014 Category: Consumer Health News Tags: Medication Source Type: news

Detecting Bone Marrow Involvement in Hodgkin LymphomaDetecting Bone Marrow Involvement in Hodgkin Lymphoma
Is FDG-PET/CT a better option than bone marrow biopsy for patients with Hodgkin's Lymphoma? Annals of Oncology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 13, 2014 Category: Consumer Health News Tags: Hematology-Oncology Journal Article Source Type: news

Measles virus used to treat bone marrow cancer
ConclusionThis research has shown that a modified measles virus can produce a long-term remission of cancerous lesions in a person with multiple myeloma that has not responded to chemotherapy. Patients such as this have limited remaining treatment options, so a new treatment would offer an important development.The article describes the response of two women in a phase I trial who received the highest dose of the virus. One of the women had a lasting response; the other woman showed some signs of an early response, but these were not as good and were not as long-lasting. As yet, we don’t know what proportion of patients ...
Source: NHS News Feed - May 16, 2014 Category: Consumer Health News Tags: Cancer Medical practice Source Type: news

Tumor cells in blood may indicate poor prognosis in early breast cancer
Tumor cells in bone marrow of early breast cancer patients predict a higher risk of relapse as well as poorer survival, but bone marrow biopsy is an invasive and painful procedure. Now, it may be possible to identify tumor cells in a routine blood sample and use them as prognostic markers, according to a study. The authors conclude that "Our data offer support for the clinical potential of CTCs to assess the individual risk of patients at the time of primary diagnosis and may be used for treatment tailoring in the absence of other strong quantitative markers." (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - May 15, 2014 Category: Science Source Type: news

Tumor cells in the blood may indicate poor prognosis in early breast cancer
(Oxford University Press USA) Tumor cells in bone marrow of early breast cancer patients predict a higher risk of relapse as well as poorer survival, but bone marrow biopsy is an invasive and painful procedure. Now, it may be possible to identify tumor cells in a routine blood sample and use them as prognostic markers, according to a study published May 15 in the Journal of the National Cancer Institute. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - May 15, 2014 Category: Cancer & Oncology Source Type: news

What scientific idea is ready for retirement?
Each year a forum for the world's most brilliant minds asks one question. This year's drew responses from such names as Richard Dawkins, Ian McEwan and Alan Alda. Here, edge.org founder John Brockman explains how the question came into being and we pick some of the best responsesEdge.org was launched in 1996 as the online version of "the Reality Club", an informal gathering of intellectuals who met from 1981 to 1996 in Chinese restaurants, artist lofts, investment banking firms, ballrooms, museums, living rooms and elsewhere. Though the venue is now in cyberspace, the spirit of the Reality Club lives on in the lively back-...
Source: Guardian Unlimited Science - January 12, 2014 Category: Science Authors: The Observer Tags: Astronomy Biology Mathematics Technology Physics Features Internet Animal behaviour The Observer Science Source Type: news

Advanced Breast Cancer First Diagnosed on Bone Marrow BiopsyAdvanced Breast Cancer First Diagnosed on Bone Marrow Biopsy
The first major North American study since 1978 of solid tumor metastases to bone marrow has found a frequency of about 0.2% for breast cancer. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 25, 2013 Category: Consumer Health News Tags: Pathology & Lab Medicine News Source Type: news

PET/CT bests gold standard bone marrow biopsy for diagnosis and prognosis of lymphoma patients
(Society of Nuclear Medicine) A more precise method for determining bone marrow involvement in patients with diffuse large B-cell lymphoma -- a key factor in tailoring patient management plans -- has been identified by researchers in a study published in the August issue of The Journal of Nuclear Medicine. Imaging with 18F-FDG positron emission tomography/computed tomography, when compared to bone marrow biopsy, was more sensitive, showed a higher negative predictive value and was more accurate. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 1, 2013 Category: Global & Universal Source Type: news

Medicine: the appliance of science
A cure for HIV? A new approach to obesity? Tailor-made therapies for cancer? Medical science surges aheadMore than once last year, researchers described leaps in medical science that were so breathtaking, and held so much potential for patients, that they immediately joined the list of fields to watch in the year ahead. In most cases, the work was, and is, at an early stage and its future success far from certain. Such is the nature of science. Most of today's breakthroughs will be tomorrow's failures. But some may go down in history for transforming how medicine is done.Often, medical science surges ahead when different a...
Source: Guardian Unlimited Science - January 1, 2013 Category: Science Authors: Ian Sample Tags: The Guardian Genetics Biology Medical research Microbiology Society Features Cancer Aids and HIV Chemistry Biochemistry and molecular biology Science Source Type: news

Stem Cells for Cell-Based Therapies
The world of stem cells We know the human body comprises many cell types (e.g., blood cells, skin cells, cervical cells), but we often forget to appreciate that all of these different cell types arose from a single cell—the fertilized egg. A host of sequential, awe-inspiring events occur between the fertilization of an egg and the formation of a new individual: Embryonic stem (ES) cells are also called totipotent cells. The first steps involve making more cells by simple cell division: one cell becomes two cells; two cells become four cells, etc. Each cell of early development is undifferentiated; that is, it is no...
Source: ActionBioscience - December 28, 2012 Category: Biology Authors: Ali Hochberg Source Type: news

Stem Cells for Cell-Based Therapies
The world of stem cells We know the human body comprises many cell types (e.g., blood cells, skin cells, cervical cells), but we often forget to appreciate that all of these different cell types arose from a single cell—the fertilized egg. A host of sequential, awe-inspiring events occur between the fertilization of an egg and the formation of a new individual: Embryonic stem (ES) cells are also called totipotent cells. The first steps involve making more cells by simple cell division: one cell becomes two cells; two cells become four cells, etc. Each cell of early development is undifferentiated; that is, it is...
Source: ActionBioscience - December 28, 2012 Category: Biology Authors: Ali Hochberg Source Type: news