Osteochondral Allograft Effective in Some Knee Cartilage Repair
No abstract available (Source: Lippincott's Bone and Joint Newsletter)
Source: Lippincott's Bone and Joint Newsletter - June 15, 2018 Category: Orthopaedics Tags: Snapshot Source Type: news

Pediatric Kidney Recipients Often Have Subclinical Inflammation
FRIDAY, June 15, 2018 -- For pediatric kidney recipients, subclinical inflammation is associated with increased risk for acute rejection and allograft failure, according to a study published online May 15 in the American Journal of... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - June 15, 2018 Category: Pharmaceuticals Source Type: news

Wright Medical wins FDA PMA for Augment injectable bone graft
Wright Medical (NSDQ:WMGI) said today it won FDA premarket approval for its Augment injectable bone graft. The bone graft won clearance for the same indications as the Amsterdam-based company’s non-injectable Augment bone graft. The newly cleared Augment Injectable consists of both recombinant human platelet derived growth factor and a blend of Type I collagen and beta tri-calcium phosphate, the company said. “In Canada, my colleagues and I have been using Augment Injectable since 2011 based upon its ideal handling characteristics and impressive clinical results.  FDA approval of Augmen...
Source: Mass Device - June 13, 2018 Category: Medical Devices Authors: Fink Densford Tags: Food & Drug Administration (FDA) Orthopedics Pre-Market Approval (PMA) Regulatory/Compliance wrightmedical Source Type: news

NuVasive launches AttraX scaffold bone graft biologic
NuVasive (NSDQ:NUVA) said today it launched its AttraX scaffold ceramic-collagen bone graft in the US, touting that the scaffold’s surface has been shown to increase bone formation for faster fusion than standard ceramic bone grafts. The San Diego-based company claims that the Attrax scaffold features a unique microstructure and microporosity that are optimized for bone formation, and that its AttraX surface technology drives the differentiation of mesenchymal stem cells into bone-forming osteoblasts without the need for added growth factors. “AttraX scaffold was easy to use and maintained excellent handli...
Source: Mass Device - June 12, 2018 Category: Medical Devices Authors: Fink Densford Tags: Business/Financial News Spinal Nuvasive Source Type: news

MiMedx Announces Executive to Lead its International Operations and Provides Update on Company's International Progress
MARIETTA, Ga., June 7, 2018 -- (Healthcare Sales & Marketing Network) -- MiMedx Group, Inc. (NASDAQ: MDXG), a leading developer and marketer of regenerative and therapeutic biologics, today announced that John D. Harris has joined the Company as its Senio... Biopharmaceuticals, Regenerative Medicine, Personnel MiMedx Group, PURION, placental tissue, allograft (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - June 7, 2018 Category: Pharmaceuticals Source Type: news

Camber Spine wins FDA nod for combining existing tech
Camber Spine Technologies has won 510(k) clearance from the FDA to market its ENZA-A Titanium Anterior Lumbar Interbody Fusion (ALIF) system, which leverages two of its existing technologies. The new device borrows from the Wayne, Penn.-based company’s first-generation ENZA, which has dual-grip anchor technology, and from its Spira line, which use spiral support arches to increase fusion rates and stabilization. The FDA approved the original Spira device in August 2017. ENZA-A is indicated for use with autogenous bone graft in patients with degenerative disc disease at one or two contiguous levels from L2 to S1 and i...
Source: Mass Device - June 4, 2018 Category: Medical Devices Authors: Nancy Crotti Tags: 510(k) Food & Drug Administration (FDA) Regulatory/Compliance Spinal camberspine Source Type: news

7 medtech stories we missed this week: May 25, 2018
[Image from unsplash.com]From Mauna Kea receiving FDA clearance to Medacta getting clearance for its pedicle screw placement guide, here are seven medtech stories we missed this week but thought were still worth mentioning. 1. Mauna Kea wins FDA nod for neurosurgery indication Mauna Kea announced in a May 24 press release that it has received FDA 510(k) clearance for its Celivizio 100 series F400 and F800 with new Confocal Miniprobe, the CranioFlex. The clearance allows the device to be used during neurosurgical procedures. The Cellvizio 100 with CranioFlex gives allows for imaging of tissue internal microstructures a...
Source: Mass Device - May 25, 2018 Category: Medical Devices Authors: Danielle Kirsh Tags: 510(k) Catheters Diagnostics Food & Drug Administration (FDA) Imaging Implants Patient Monitoring Regulatory/Compliance Bonesupport collagenmatrix crossroadsextremitysystems Implanet Mauna Kea Technologies MC10 Medacta xablec Source Type: news

How Orthopedics Innovation Doesn ’t Get Lost In Shuffle
What are some of the growing trends and unmet needs in the orthopedics market? If you’re a surgeon, just how do you convince the CEO of a hospital to invest in these technologies? During MDM East, held in New York from June 12-14,  Michael Levy, MD will be a part of two panels that will touch on some of these subjects. The panels are titled “Prominent Physicians Address Unmet Needs in Orthopedics” and “Selling Your Idea to Upper Management.” Levy is an expert in the field and has been involved in orthopedics for 34 years including basic research, orthopedic product development, and c...
Source: MDDI - May 24, 2018 Category: Medical Devices Authors: Omar Ford Tags: Orthopedics Source Type: news

FDA clears Zimmer Biomet ’ s 3D-printed titanium Zyston spinal implant
Zimmer Biomet (NYSE:ZBH) said yesterday it won FDA 510(k) clearance for its Zyston Strut open titanium interbody spacer system, touting it as the company’s first 3D-printed titanium spinal implant. The Zyston Strut open titanium system is a family of lumbar cages intended to enhance strength, graft capacity and visualization capabilities of interbody spacers in spinal fusion cases, the Warsaw, Ind.-based company said. The system also includes surgical instruments needed for insertion, manipulation and removal. The newly cleared cages will be available in a series of sizes to accommodate different patient anatomi...
Source: Mass Device - May 23, 2018 Category: Medical Devices Authors: Fink Densford Tags: 510(k) Food & Drug Administration (FDA) Regulatory/Compliance Spinal zimmerbiomet Source Type: news

Therapies After Autograft Failure in a Patient With Melanoma Therapies After Autograft Failure in a Patient With Melanoma
This report describes a case of amelanotic melanoma of the foot initially diagnosed and treated as a pressure ulcer.Wounds (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 23, 2018 Category: Consumer Health News Tags: General Surgery Journal Article Source Type: news

Does anterior cruciate ligament reconstruction affect the outcome of osteochondral allograft transplantation? A matched cohort study with a mean follow-up of 6 years - T írico LEP, McCauley JC, Pulido PA, Bugbee WD.
BACKGROUND: Few studies have evaluated the influence of anterior cruciate ligament (ACL) reconstruction on the outcome of cartilage repair. Hypothesis/Purpose: The purpose was to investigate the association between ACL reconstruction and functional outcome... (Source: SafetyLit)
Source: SafetyLit - May 21, 2018 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Medtronic wins expanded indications for Infuse bone growth protein
Medtronic (NYSE:MDT) said today it won expanded approval from the FDA for its Infuse bone growth protein implant, marking the second expansion for the implant over the past two years. The Infuse implant contains the active ingredient rhBMP-2, a manufactured version of a bone growth protein normally present in the body. The Infuse device is designed for use with certain Medtronic interbody fusion devices to treat lumbar degenerative disc disease. “Different spine patients can have very different surgical needs, so the more options surgeons have to combine a clinically-proven bone grafting technology like Infuse with d...
Source: Mass Device - April 30, 2018 Category: Medical Devices Authors: Fink Densford Tags: Food & Drug Administration (FDA) Regulatory/Compliance Spinal Medtronic Source Type: news

Newly Founded Company, Datum Orthobiologics, to Apply Dental Technology in Orthopedics
Collagen Technology Mimics Nature, to Regenerate Bone and Cartilage NESS ZIONA, Israel, April 24, 2018 -- (Healthcare Sales & Marketing Network) -- Datum Biotech Ltd. has announced the founding of Datum Orthobiologics Ltd. Datum Orthobiologics will foc... Devices, Orthopaedic, Regenerative Medicine Datum Biotech, Datum Orthobiologics, bone graft, GLYMATRIX (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - April 24, 2018 Category: Pharmaceuticals Source Type: news

Infected tooth with sinus perforation treatment: feedback?
A middle aged woman presented with a swollen gingiva buccal to tooth #15 which had a previous RCT and crown. I am wondering if I should place a membrane and bone graft after extracting the tooth or if I should let it drain on its own?The postInfected tooth with sinus perforation treatment: feedback? appeared first onOsseoNews Dental Implants. (Source: Dental Implants Discussed by Experts)
Source: Dental Implants Discussed by Experts - April 17, 2018 Category: Dentistry Authors: osseonews Tags: Clinical Cases Regenerative Surgical Source Type: news

Spineology touts 1-year OptiMesh lumbar interbody fusion study results
Spinal tech developer Spineology today released 12-month results from a study of its OptiMesh deployable implant designed for use in instrumented lumbar interbody fusion procedures to treat degenerative disc disease. Results from the Scout trial were presented at the annual meeting of the International Society for the Advancement of Spine Surgery in Toronto, the St. Paul, Minn.-based company said. “We are grateful to Dr. Chi and all the Scout investigators for their dedication in helping us to complete this important clinical trial. We look forward to completing the patient follow-up and gaining the market ...
Source: Mass Device - April 12, 2018 Category: Medical Devices Authors: Fink Densford Tags: Clinical Trials Spinal Spineology Source Type: news

Sinus Tract Next to Tenting Screw After Bone Graft and Implant Placement: How to Resolve?
After 5 months of uneventful healing of implants, I now see a small lesion resembling a sinus tract that is present in the immediate vicinity of one tenting screw.The postSinus Tract Next to Tenting Screw After Bone Graft and Implant Placement: How to Resolve? appeared first onOsseoNews Dental Implants. (Source: Dental Implants Discussed by Experts)
Source: Dental Implants Discussed by Experts - April 11, 2018 Category: Dentistry Authors: osseonews Tags: Clinical Questions Surgical Source Type: news

Ridge Augmentation: Thoughts about Bond Apatite synthetic Bone Graft?
Any thoughts on using synthetic bone augmentation materials, like Bond Apatite for lateral ridge augmentation or ridge widening?The postRidge Augmentation: Thoughts about Bond Apatite synthetic Bone Graft? appeared first onOsseoNews Dental Implants. (Source: Dental Implants Discussed by Experts)
Source: Dental Implants Discussed by Experts - April 6, 2018 Category: Dentistry Authors: osseonews Tags: Clinical Questions Regenerative Source Type: news

7 medtech stories we missed this week: March 23, 2018
[Image from unsplash.com]From Medizone’s evaluation deal to Advantis Medical Imaging getting CE Mark approval, here are seven medtech stories we missed this week but thought were still worth mentioning. 1. Medizone inks AsepticSure evaluation deal with commercial cleaning products maker Innovasource Medizone announced in a March 22 press release that it has signed a product evaluation agreement with Innovasource. As part of the agreement, Innovasource will be leading the evaluation of the AsepticSure system and compare it to existing cleaning practices in a number of facilities and settings. AsepticSure is desig...
Source: Mass Device - March 23, 2018 Category: Medical Devices Authors: Danielle Kirsh Tags: 510(k) Food & Drug Administration (FDA) Hospital Care Imaging Implants Patient Monitoring Regulatory/Compliance Respiratory advantismedicalimaging aziyobiologics Balt endospan Medizone MedTech Olympus Respiratory Motion Source Type: news

LifeNet Health launches unique, life-saving vascular allograft
AngioGraft® Aortoiliac Artery, the first to offer pressurized sizing, offers unparalleled efficiency and precision in aortic reconstruction VIRGINIA BEACH, Va., March 19, 2018 -- (Healthcare Sales & Marketing Network) -- LifeNet Health today announc... Devices, Cardiology, Surgery, Product Launch LifeNet Health, AngioGraft, Aortoiliac Artery, vascular allograft (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - March 19, 2018 Category: Pharmaceuticals Source Type: news

Cerapedics wins FDA IDE nod for P-15L bone graft trial
Cerapedics said today it won FDA investigational device exemption approval to launch a clinical trial examining the safety and efficacy of its P-15L Peptide Enhanced bone graft. In the trial, the Wesminster, Colo.-based company will explore the use of the P-15L graft as it compares to autografts in transforaminal lumbar interbody fusion procedures meant for treating degenerative disk disease. “Prior research of this proprietary P-15 technology has demonstrated potential benefits in fusion rates, neurological outcomes and safety in cervical and lumbar fusions. We are pleased to participate in a new study evaluati...
Source: Mass Device - March 14, 2018 Category: Medical Devices Authors: Fink Densford Tags: Clinical Trials Food & Drug Administration (FDA) Regulatory/Compliance Spinal Cerapedics Inc. Source Type: news

Cerapedics Receives FDA IDE Approval to Initiate Study of P-15L Bone Graft for Transforaminal Lumbar Interbody Fusion Surgery
Pivotal study to evaluate next-generation synthetic small peptide technology (P-15) compared to autograft in most common spine procedure WESTMINSTER, Colo., March 14, 2018 -- (Healthcare Sales & Marketing Network) -- Cerapedics, a privately-held orthob... Devices, Orthopaedic, FDA Cerapedics, orthobiologic, i-FACTOR, Peptide Enhanced Bone Graft (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - March 14, 2018 Category: Pharmaceuticals Source Type: news

Autogenous Bone: Most Effective Material?
Two recent studies show good results with autogenous bone grafts, long considered the most effective material in bone regeneration procedures.The postAutogenous Bone: Most Effective Material? appeared first onOsseoNews Dental Implants. (Source: Dental Implants Discussed by Experts)
Source: Dental Implants Discussed by Experts - March 13, 2018 Category: Dentistry Authors: osseonews Tags: Implant News Surgical Source Type: news

Osteochondral allograft transplantation effective for certain knee cartilage repairs
(American Orthopaedic Society for Sports Medicine) Isolated femoral condyle lesions account for 75 percent of the cartilage repair procedures performed in the knee joint, and physicians have a variety of techniques to consider as part of surgical treatment. Osteochondral allograft transplantation (OCA) is a valuable and successful approach for this condition, as described by research presented today at the American Orthopaedic Society for Sports Medicine's Specialty Day in New Orleans. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 10, 2018 Category: International Medicine & Public Health Source Type: news

Medtronic wins one lawsuit, settles state AG probes over Infuse
Medtronic (NYSE:MDT) said a shareholder lawsuit brought over its Infuse bone-growth protein is over, after the U.S. Supreme Court declined to review the case. Approved in 2002 for use in spinal fusion surgery, Infuse at one point had annual sales of nearly $1 billion. The bone-grafting product has since been linked to abnormal bone growth, certain cancers and male reproductive problems. Fridley, Minn.-based Medtronic has been accused of not only downplaying the product’s risks but also promoting it for off-label use. The derivative lawsuit, brought in March 2012 by  investor Charlotte Kokocinski in the U.S. Dist...
Source: Mass Device - March 5, 2018 Category: Medical Devices Authors: Brad Perriello Tags: Legal News Orthopedics Regenerative Medicine Medtronic Source Type: news

Human bone tissue grown from a patient's fat cells in a lab, then implanted to finish growing inside the patient's body
(Natural News) Thanks to an extraordinary medical procedure, a man is on the road to recovering from a fractured tibia with a bone graft created from his own fat cells. This isn’t a work of science fiction; it’s the result of efforts made by Bonus BioGroup, an Israel-based biomedical company. According to the TimesOfIsrael.com, a... (Source: NaturalNews.com)
Source: NaturalNews.com - March 4, 2018 Category: Consumer Health News Source Type: news

Collaboration Is Key in Bioventus ’s Path Toward Innovation
Durham, NC-based Bioventus is hoping to expand its position in the allograft market through a collaboration with LifeLink Foundation. The accord will have the companies work together to co-develop a next-generation bone allograft solution for use in spine and trauma surgery. Bivoentus specializes in orthobiologic products for bone healing, bone graft, and knee osteoarthritis. “LifeLink is a fully equipped tissue bank,” Samson Tom, vice president of research and development at Bioventus, told MD+DI. “Here at Bioventus, we have significant infrastructure, but we are not a tissue bank. We recognize partneri...
Source: MDDI - February 27, 2018 Category: Medical Devices Authors: Omar Ford Tags: Business Source Type: news

Purulent discharge and radiolucent area around implant: Advice?
I placed an implant at area 32 with bone graft.  Saw patient after 18 days and there is purulent discharge and a radiolucent area around the implant.  (Source: Dental Implants Discussed by Experts)
Source: Dental Implants Discussed by Experts - February 19, 2018 Category: Dentistry Authors: osseonews Tags: Clinical Cases Surgical Source Type: news

Distal tibial allograft reconstruction and Latarjet may offer similar outcomes for recurrent anterior shoulder instability
According to a study published online in The American Journal of Sports Medicine, fresh distal tibia allograft (DTA) reconstruction and the Latarjet procedure may offer similar outcomes for recurrent anterior shoulder instability.  (Source: Orthogate - Latest News)
Source: Orthogate - Latest News - February 10, 2018 Category: Orthopaedics Tags: Featured Editors Choice News Source Type: news

Detecting and treating dnDSA early preserves allograft function
(Children's National Health System) Monitoring and treating de novo donor-specific antibodies before they could cause graft damage helped to decrease dnDSA in a majority of pediatric kidney transplant recipients at Children National Health System and prevented graft failure in the first few years. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 5, 2018 Category: International Medicine & Public Health Source Type: news

Finland ’ s BBS-Bioactive Bone Substitute plans $10m IPO
BBS-Bioactive Bone Substitutes said today that’s its planning for an initial public offering later this year it hopes will bring in some $10 million. Oulu, Finland-based BBS said it plans to list 1.5 million shares at €5.50 apiece beginning Feb. 5 for gross proceeds of €7.7 million, or roughly $9.6 million. The shares, due to trade on the First North Finland and NASDAQ First North Sweden exchanges, would represent about 23.9% of BBS’s total shares if the flotation is fully subscribed. Based on proteins extracted from reindeer bone, BBS’s Artebone is designed to be injected to the site ...
Source: Mass Device - January 31, 2018 Category: Medical Devices Authors: Brad Perriello Tags: Funding Roundup Initial Public Offering (IPO) Orthopedics Regenerative Medicine Wall Street Beat bioactivebonesolutions Source Type: news

Socket grafting after extraction of an infected endodontic tooth?
How do you treat and clean the socket after extraction of an infected endodontic tooth and prepare it for the bone graft for ridge preservation? (Source: Dental Implants Discussed by Experts)
Source: Dental Implants Discussed by Experts - January 30, 2018 Category: Dentistry Authors: osseonews Tags: Clinical Cases Clinical Questions Source Type: news

The University City Science Center is backing development of NJIT's novel bone graft tech
(New Jersey Institute of Technology) Treena Arinzeh, director of NJIT's Tissue Engineering and Applied Biomaterials Laboratory, has been awarded a grant from the University City Science Center in Philadelphia to help commercialize technology she is developing to reduce the recovery time and cost associated with bone grafts. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 29, 2018 Category: International Medicine & Public Health Source Type: news

West Sacramento-based bone graft company raises funds, wins federal clearance
Molecular Matrix Inc. has raised money and passed a major regulatory milestone for its product that helps bone heal. (Source: bizjournals.com Health Care News Headlines)
Source: bizjournals.com Health Care News Headlines - January 19, 2018 Category: Health Management Authors: Mark Anderson Source Type: news

West Sacramento-based bone graft company raises funds, wins federal clearance
Molecular Matrix Inc. has raised money and passed a major regulatory milestone for its product that helps bone heal. (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - January 19, 2018 Category: Biotechnology Authors: Mark Anderson Source Type: news

New Kleiner Spine Graft Delivery Tool Improves Outcomes for Patients, Surgeons, Hospitals and Payers
DENVER, Jan. 10, 2018 -- (Healthcare Sales & Marketing Network) -- Kleiner Device Labs today announced full commercial availability of a new spinal bone graft delivery tool, the KG® 1, featuring a patented design that facilitates less-invasive procedu... Devices, Oncology, Neurosurgery, Product Launch Kleiner Device Labs, bone graft (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - January 10, 2018 Category: Pharmaceuticals Source Type: news

Do I have to place a membrane in this immediate implant case?
I placed an implant in the maxillary lateral incisor site immediately after extraction and did a small particulate bone graft. (Source: Dental Implants Discussed by Experts)
Source: Dental Implants Discussed by Experts - January 5, 2018 Category: Dentistry Authors: osseonews Tags: Clinical Questions Surgical Source Type: news

RTI Surgical buys Zyga Tech and its SImmetry sacroiliac fusion device, updates 2018 outlook
RTI Surgical (NSDQ:RTIX) yesterday announced an agreement to purchase Zyga Technology and its SImmetry sacroiliac joint fusion system and today released updated guidance for 2018 and beyond. The Alachua, Fla.-based RTI surgical said that Zyga Technology has approximately 30 employees and $4 million in annual revenue, and that it plans to fund the acquisition through a combination of cash and through borrowing under its existing credit facility. Terms of the deal were not disclosed, and RTI Surgical it expects the deal to close when the Delaware Department of State re-opens as it is currently closed due to incleme...
Source: Mass Device - January 5, 2018 Category: Medical Devices Authors: Fink Densford Tags: Business/Financial News Mergers & Acquisitions Spinal RTI Surgical Source Type: news

NuVasive wins expanded FDA nod, launches interbody fusion devices
NuVasive Inc. (NSDQ:NUVA) said today it won expanded FDA 510(k) clearance for its Cohere cervical interbody fusion device and that it launched the Coalesce thoracolumbar interbody fusion device. Both the launch and updated clearance comes from the company’s acquisition of Vertera Spine, which it closed last September. The Cohere and Coalesce implants use porous version of the material polyetheretherketone, or PEEK, and are designed to provide three-dimensional achitecture to elicit and encourage bone growth, San Diego, Calif.-based NuVasive said. “Our strategy in building our AMS portfolio is to ...
Source: Mass Device - January 4, 2018 Category: Medical Devices Authors: Fink Densford Tags: 510(k) Business/Financial News Food & Drug Administration (FDA) Regulatory/Compliance Spinal Nuvasive Source Type: news

Distants between implants considerable: long-term success?
I placed 2 implants in the maxillary right posterior quadrant using an indirect sinus lift without bone grafts.  I am concerned about a few issues. (Source: Dental Implants Discussed by Experts)
Source: Dental Implants Discussed by Experts - January 2, 2018 Category: Dentistry Authors: gkaplowitz Tags: Clinical Cases Surgical Source Type: news

Anika Therapeutics wins FDA nod for bone void filler
Anika Therapeutics (NSDQ:ANIK) said today that it won 510(k) clearance from the FDA for its hyaluronic acid-based bone void filler The indication covers filling bone voids or defects that aren’t intrinsic to the stability of the bone, created during surgery or the result of traumatic injury. Made of a synthetic, biocompatible bone graft substitute material, the filler is injected into a void and hardens at body temperature. It’s then resorbed and replaced by new bone growth. Get the full story at our sister site, Drug Delivery Business News. The post Anika Therapeutics wins FDA nod for bone void filler appeared...
Source: Mass Device - December 27, 2017 Category: Medical Devices Authors: Brad Perriello Tags: Food & Drug Administration (FDA) Orthopedics Regulatory/Compliance Anika Therapeutics Inc. Source Type: news

Flapless procedure with no graft: Failing or Not?
I placed an immediate 3.5x13 Nobel Replace conical connection implant in area #7 using a flapless procedure with gap space about 1mm to 1.5, which was impossible to fill with bone graft. (Source: Dental Implants Discussed by Experts)
Source: Dental Implants Discussed by Experts - December 18, 2017 Category: Dentistry Authors: osseonews Tags: Clinical Cases Surgical Source Type: news

Knee Stability and Alterations in Synovial Fluid After Arthroscopic ACL Reconstruction With Hamstring Autograft or Hamstring Allograft
No abstract available (Source: Lippincott's Bone and Joint Newsletter)
Source: Lippincott's Bone and Joint Newsletter - December 17, 2017 Category: Orthopaedics Tags: CME Article Source Type: news

Dehydrated Amniotic Membrane Allograft for Extremity Wounds Dehydrated Amniotic Membrane Allograft for Extremity Wounds
What benefits might this novel amniotic allograft offer in the treatment of lower extremity wounds?Wounds (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 15, 2017 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news

Medtronic Settles States' Probe Into Infuse Marketing for $12 Million Medtronic Settles States' Probe Into Infuse Marketing for $12 Million
Medtronic Plc has agreed to pay $12 million to resolve claims that the company engaged in a deceptive marketing strategy to promote its Infuse bone graft product used in spinal surgery, the Massachusetts attorney general said on Wednesday.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - December 14, 2017 Category: Consumer Health News Tags: Medscape Today News Source Type: news

Medtronic Forks Over $12 Million in Deceptive Marketing Settlement
Medtronic has agreed to pay a total of $12 million in a five-state settlement of litigation over its controversial Infuse bone graft device. Oregon Attorney General Ellen Rosenblum announced the settlement with Medtronic Sofamor Danek Inc. and Medtronic Sofamor Danek USA Inc. to resolve allegations that the company unlawfully promoted Infuse, used in spinal fusion procedures, to doctors. Other states participating in the settlement are California, Illinois, Massachusetts, and Washington. Oregon alleged that Medtronic made deceptive claims about Infuse by using trusted scientific publications to rep...
Source: MDDI - December 14, 2017 Category: Medical Devices Authors: Nancy Crotti Tags: Regulatory and Compliance Medical Device Business Source Type: news

Sintered Xenograft over Allograft?
There is an article which describes using sintered xenograft (bovine) over an allograft for Ridge Augmentation. Any thoughts on this technique? (Source: Dental Implants Discussed by Experts)
Source: Dental Implants Discussed by Experts - December 14, 2017 Category: Dentistry Authors: osseonews Tags: Clinical Questions Regenerative Source Type: news

Medtronic to pay $12m to settle Infuse false marketing claims
Medtronic‘s (NYSE:MDT) spinal devices division has agreed to pay $12 million to settle allegations that the medtech giant made false claims to doctors and patients about its Infuse bone-growth protein, according to a Star Tribune report. States joining in the settlement include California, Massachusetts, Illinois, Washington and Oregon, according to the report. In Oregon, Attorney General Ellen Rosenblum said that Medtronic Sofamor Danek agreed to settle claims that it manipulated journal articles to make its controversial Infuse protein appear safer than it was to sell more products, breaking Oregon law, the Star Tr...
Source: Mass Device - December 13, 2017 Category: Medical Devices Authors: Fink Densford Tags: Legal News Spinal Medtronic Source Type: news

Medtronic settles states' probe into Infuse marketing for $12 million
BOSTON (Reuters) - Medtronic Plc has agreed to pay $12 million to resolve claims that the company engaged in a deceptive marketing strategy to promote its Infuse bone graft product used in spinal surgery, the Massachusetts attorney general said on Wednesday. (Source: Reuters: Health)
Source: Reuters: Health - December 13, 2017 Category: Consumer Health News Tags: healthNews Source Type: news

C-reactive protein promotes bone destruction in human myeloma through the CD32-p38 MAPK-Twist axis
Bone destruction is a hallmark of myeloma and affects 80% of patients. Myeloma cells promote bone destruction by activating osteoclasts. In investigating the underlying mechanism, we found that C-reactive protein (CRP), a protein secreted in increased amounts by hepatocytes in response to myeloma-derived cytokines, activated myeloma cells to promote osteoclastogenesis and bone destruction in vivo. In mice bearing human bone grafts and injected with multiple myeloma cells, CRP bound to surface CD32 (also known as FcRII) on myeloma cells, which activated a pathway mediated by the kinase p38 MAPK and the transcription factor ...
Source: Signal Transduction Knowledge Environment - December 12, 2017 Category: Science Authors: Yang, J., Liu, Z., Liu, H., He, J., Yang, J., Lin, P., Wang, Q., Du, J., Ma, W., Yin, Z., Davis, E., Orlowski, R. Z., Hou, J., Yi, Q. Tags: STKE Research Articles Source Type: news

State of the U.S. Market for Dental Bone Graft Substitutes and Other Biomaterials
The dental bone graft substitute and other biomaterials market includes dental bone graft substitutes (DBGS), dental growth factors, and dental barrier membranes. The DBGS market is relatively stable with an increasing shift towards allografts. Already representing the largest segment of total DBGS materials, the allograft market is expected to grow at a 5.8% compound annual growth rate (CAGR) by 2023. The most innovative market in dental biomaterials is dental growth factor technology. However, these products have been slow to make strides on the market due to their relatively high price point. As such, growth within the ...
Source: MDDI - December 9, 2017 Category: Medical Devices Authors: Salma Mashkoor and Celine Mashkoor Tags: Materials Source Type: news