Rescue stem cell allograft in intensive care unit patients during septic shock with multi-organ failure
We describe what we believe to be the first two cases of patients who received an allograft in intensive care unit (ICU) despite severe septic shock with multi-organ failure (MOF). Allograft should be considered as a rescue therapy in ICU for patients with aplasia, during septic shock with multi-organ failure, however close multidisciplinary discussion is required between intensivists and onco-hematologists. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - January 23, 2020 Category: Consumer Health News Source Type: news
20 Private Companies to Watch in 2020
MD+DI has taken a hard look at the private medtech sector and developed this list of 20 private companies we will be paying particularly close attention to in the new year. It was not an easy task. There are so many interesting private companies in the industry right now that we started with a much longer list and whittled it down to the 20 companies that stood out most to us.
So without further ado, here are the 20 companies that made the cut:
4C Medical is developing the AltaValve, a transcatheter mitral valve replacement (TMVR) platform designed to address mitr...
Source: MDDI - December 24, 2019 Category: Medical Devices Authors: Amanda Pedersen Tags: Business Source Type: news
20 Private Medtech Companies to Watch in 2020
MD+DI has taken a hard look at the private medtech sector and developed this list of 20 private companies we will be paying particularly close attention to in the new year. It was not an easy task. There are so many interesting private companies in the industry right now that we started with a much longer list and whittled it down to the 20 companies that stood out most to us.
So without further ado, here are the 20 companies that made the cut:
4C Medical is developing the AltaValve, a transcatheter mitral valve replacement (TMVR) platform designed to address mitr...
Source: MDDI - December 24, 2019 Category: Medical Devices Authors: Amanda Pedersen Tags: Business Source Type: news
A mouse model of prostate cancer bone metastasis in a syngeneic immunocompetent host
(Impact Journals LLC) The research team reports the establishment of B6Ca P, an allograft tumor line from a Hi-Myc transgenic mouse that had been backcrossed onto C57BL/6J background. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - December 4, 2019 Category: Cancer & Oncology Source Type: news
New Score Accurately Predicts Risk of Kidney Allograft Loss New Score Accurately Predicts Risk of Kidney Allograft Loss
A new eight-factor scoring system, iBox, accurately predicts the risk of allograft loss in patients receiving kidney transplants, according to an international study.Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - October 30, 2019 Category: Pathology Tags: Transplantation News Source Type: news
Autogenous bone graft after tenting?
I posted a tenting case question a couple months ago and it did fine. I gained 3mm height and I want to gain another 5mm. I have used 5mm block bovine grafts in the past but I am on board with an autogenous block graft.The postAutogenous bone graft after tenting? appeared first onOsseoNews Dental Implants. (Source: Dental Implants Discussed by Experts)
Source: Dental Implants Discussed by Experts - October 24, 2019 Category: Dentistry Authors: osseonews Tags: Clinical Questions Regenerative Source Type: news
Protecting the Heart Allograft With a Statin Protecting the Heart Allograft With a Statin
An intriguing study investigates whether a single dose of a statin administered to a brain-dead heart donor might improve outcomes for the transplant recipient.Circulation (Source: Medscape Transplantation Headlines)
Source: Medscape Transplantation Headlines - October 4, 2019 Category: Transplant Surgery Tags: Cardiology Journal Article Source Type: news
Medtronic Announces New Infuse Trial on Heels of NASS Panel
This study has the potential to add to the broader clinical and scientific evidence regarding use of Infuse and may allow surgeons to better understand its safe and effective use in TLIF procedures.†(Source: MDDI)
Source: MDDI - September 28, 2019 Category: Medical Devices Authors: Amanda Pedersen Tags: Orthopedics Source Type: news
NASS Panel Revisits Medtronic Infuse Bone Graft Controversy
A panel at the North American Spine Society (NASS) meeting in Chicago, IL, revisited a controversy that dates back nearly 15 years surrounding Medtronic’s Infuse bone graft, which contains a recombinant version of bone morphogenetic protein-2 (rhBMP-2).
The timing of Wednesday’s panel session, “The Biologic Hasn’t Changed but the Evidence Has,†was interesting given Medtronic was already gearing up to announce on Thursday that FDA has signed off on a new Infuse trial that could lead to the product being cleared for a new indication.
&...
Source: MDDI - September 25, 2019 Category: Medical Devices Authors: Amanda Pedersen Tags: Orthopedics Source Type: news
Cervical vertebral body replacement system made from PEEK-Optima HA receives FDA 510(k) clearance
Omnia Medical (Morgantown, WV) has been granted the first FDA 510(k) clearance for a cervical vertebral body replacement (VBR) system manufactured from PEEK-Optima HA Enhanced polymer from Invibio Biomaterial Solutions (Thornton Cleveleys, UK). The so-called Boxcar system is designed for use in cervical-corpectomy procedures, the replacement of a collapsed, damaged or unstable vertebral body located in the cervical spine.
Robert Gewirtz, a neurosurgeon based in Columbus, OH, collaborated on the development of the Boxcar VBR product. “I see many patients that require a cervical corpectomy, and it's excitin...
Source: MDDI - September 24, 2019 Category: Medical Devices Tags: Plastics Today Source Type: news
Mallinckrodt Announces Positive Top-line Results from Pivotal Phase 3 Clinical Trial of StrataGraft(R) Regenerative Tissue in Patients with Deep Partial-thickness Thermal Burns
Study met both co-primary endpoints with high statistical significance, demonstrating autograft sparing and durable wound closure at three months with StrataGraft
Company plans to submit Biologics License Application to the U.S. Food and Drug Administra... Regenerative Medicine Mallinckrodt, StrataGraft, regenerative tissue, burn wounds (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - September 23, 2019 Category: Pharmaceuticals Source Type: news
CareDx Enrolls First Patient in OKRA Registry
CareDx has enrolled the first patient in the Outcomes of KidneyCare in Renal Allografts (OKRA) registry. There will be about 4,000 patients in the Brisbane, CA-based company’s registry, which is statistically powered to determine the use of KidneyCare and provide real-world data on the use of KidneyCare and AlloSure.
OKRA targets more than 50 transplant centers and will enroll 1,500 newly transplanted patients, complementing the Kidney Outcomes Allograft Registry (KOAR) with 1,500 patients, matching both arms with 1,000 control patients.
“Data on 4,000 patients provides the ultimate regi...
Source: MDDI - September 18, 2019 Category: Medical Devices Authors: Omar Ford Tags: Business Source Type: news
New hydrogels show promise in treating bone defects
Bioengineers and dentists from the UCLA School of Dentistry have developed a new hydrogel that is more porous and effective in promoting tissue repair and regeneration compared to hydrogels that are currently available. Once injected in a mouse model, the new hydrogel is shown to induce migration of naturally occurring stem cells to better promote bone healing. Current experimental applications using hydrogels and stem cells introduced into the body or expensive biological agents can come with negative side effects.The findings, published online in the journal Nature Communications, suggest that in the near future the...
Source: Dental Technology Blog - August 27, 2019 Category: Dentistry Source Type: news
New hydrogels show promise in treating bone defects
Bioengineers and dentists from the UCLA School of Dentistry have developed a new hydrogel that is more porous and effective in promoting tissue repair and regeneration compared to hydrogels that are currently available. Once injected in a mouse model, the new hydrogel is shown to induce migration of naturally occurring stem cells to better promote bone healing. Current experimental applications using hydrogels and stem cells introduced into the body or expensive biological agents can come with negative side effects.The findings, published online in the journal Nature Communications, suggest that in the near future the ...
Source: UCLA Newsroom: Health Sciences - August 19, 2019 Category: Universities & Medical Training Source Type: news
Islet-Allograft Tolerance Possible in Monkeys Without Long-Term Immunosuppression Islet-Allograft Tolerance Possible in Monkeys Without Long-Term Immunosuppression
Long-term tolerance of islet allografts may be possible without prolonged immunosuppression, according to studies in monkeys.Reuters Health Information (Source: Medscape Allergy Headlines)
Source: Medscape Allergy Headlines - August 17, 2019 Category: Allergy & Immunology Tags: Transplantation News Source Type: news
