Fight Aging! Newsletter, October 21st 2019
In this study, AT1-AAs were detected in the sera of patients with peripheral arterial disease (PAD) and the positive rate was 44.44% vs. 17.46% in non-PAD volunteers. In addition, analysis showed that AT1-AAs level was positively correlated with PAD. To reveal the causal relationship between AT1-AAs and vascular aging, an AT1-AAs-positive rat model was established by active immunization. The carotid pulse wave velocity was higher, and the aortic endothelium-dependent vasodilatation was attenuated significantly in the immunized rats. Morphological staining showed thickening of the aortic wall. Histological examination showe...
Source: Fight Aging! - October 20, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Autoimmunity Against AT1 Receptor Spurs Endothelial Cellular Senescence and Vascular Aging
In this study, AT1-AAs were detected in the sera of patients with peripheral arterial disease (PAD) and the positive rate was 44.44% vs. 17.46% in non-PAD volunteers. In addition, analysis showed that AT1-AAs level was positively correlated with PAD. To reveal the causal relationship between AT1-AAs and vascular aging, an AT1-AAs-positive rat model was established by active immunization. The carotid pulse wave velocity was higher, and the aortic endothelium-dependent vasodilatation was attenuated significantly in the immunized rats. Morphological staining showed thickening of the aortic wall. Histological examination showe...
Source: Fight Aging! - October 17, 2019 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Injectable Bone Scaffolding Made of Plant Cellulose
The majority of bone implants, cements, and grafts are hard objects that don’t always work well in filling the space they’re supposed to inhabit. Soft objects can gently expand and relocate their mass evenly over a volume, and they tent to be less dense so as to leave room for cells to make home inside of.
Researchers at the University of British Columbia and McMaster University in Canada have just reportred on a plant cellulose-based bone scaffolds that can be injected into areas of damage. The material allows native tissue cells to invade into its interior and to propagate. Eventually, because it is biodegrad...
Source: Medgadget - March 20, 2019 Category: Medical Devices Authors: Editors Tags: Materials Nanomedicine Source Type: blogs
Bioreactors Inside Body Grow New Bones for Transplantation
This study demonstrated that we could create viable bone grafts from artificial bone substitute materials.
Study in Proceedings of the National Academy of Sciences: Biomaterials-aided mandibular reconstruction using in vivo bioreactors…
Via: Rice… (Source: Medgadget)
Source: Medgadget - March 19, 2019 Category: Medical Devices Authors: Editors Tags: ENT Genetics Materials Neurosurgery Source Type: blogs
Alternative Orthopedic Fixation Company Ossio Developing Absorbable Fixation Devices
Ossio, a medical device company with offices in Caesarea, Israel and Woburn, Massachusetts, recently announced a $22 million Series A venture investment round led by LA-based OCV Partners. This brings the company’s total venture funding to $35 million. This technology received FDA 510(k) clearance in January 2019.
Ossio has developed the OSSIOfiber Intelligent Bone Regeneration Technology, which provides a biocompatible framework for bone regeneration after traumatic fractures or orthopedic surgery. The platform is a bioabsorbable polymer resin (PLDLA) combined with natural mineral fibers, constructed in a sturdy matrix...
Source: Medgadget - March 15, 2019 Category: Medical Devices Authors: Kurt Yaeger Tags: Materials Orthopedic Surgery Source Type: blogs
Mid-Semester Check-Ins Keep Your A & P Course on Track | Episode 38
00:45 | Sperm Speed02:48 | Sponsored by HAPS03:32 | Hematopoiesis in the Gut07:04 | Sponsored by AAA07:22 | Swallow Legos Much?10:41 | New Sponsor: MS-HAPI Program15:23 |Featured: Mid-Semester Check-Ins Keep Your A&P Course on TrackIf you cannot see or activate the audio playerclick here.Questions& Feedback:1-833-LION-DEN (1-833-546-6336)FollowThe A&P Professor onTwitter,Facebook,Blogger,Nuzzel,Tumblr, orInstagram! Vulnerability sounds like truth and feels like courage. Truth and courage aren't always comfortable, but they're never weakness. (Bren é Brown) 1 | Sperm Speed2 minutesWe know that so...
Source: The A and P Professor - February 25, 2019 Category: Physiology Authors: Kevin Patton Source Type: blogs
Bioengineered Bone Grafts for Large Bone Defects
Researchers at the New York Stem Cell Foundation have developed a technique to produce bioengineered bone grafts for large bone defects, which are currently difficult to treat using conventional techniques.
To deal with bone defects, clinicians currently use either synthetic materials or bone grafts from the patient or a donor. However, these grafts can trigger an immune response, and do not always integrate with the surrounding bone. “Bone defects obtained in disease or injury are a growing issue, and having effective treatment options in place for personalized relief, no matter the severity of a patient’s conditi...
Source: Medgadget - July 18, 2018 Category: Medical Devices Authors: Conn Hastings Tags: Genetics Materials Orthopedic Surgery Source Type: blogs
Fight Aging! Newsletter, June 4th 2018
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more.
This content is...
Source: Fight Aging! - June 3, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Exploring the Utility of Decellularized Muscle Grafts in Animal Models
In this open access paper, researchers explore the utility of decellularized muscle grafts to repair severe injury. Decellularization is the process by which a donor tissue is cleared of cells, leaving behind the extracellular matrix. This intricate structure includes capillary networks and chemical cues to guide cells, line items that the research community has yet to reliably recreate when building tissue from scratch. Over the past decade, researchers have demonstrated the ability to repopulate decellularized tissue with patient-derived cells, a capacity that in principle allows for the production of patient-matched don...
Source: Fight Aging! - May 29, 2018 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Gold standard for cardiac allograft rejection – Cardiology MCQ – Answer
>>>Available Here with Free Look Inside Option
Correct Answer: 3. Endomyocardial Biopsy
Original methods to detect cardiac allograft rejection were signs of heart failure and ECG abnormalities. But these were quite insensitive.
Endomyocardial biopsies are taken from the right ventricular aspect of the interventricular septum using bioptomes introduced through right internal jugular vein.
Back to question (Source: Cardiophile MD)
Source: Cardiophile MD - January 4, 2018 Category: Cardiology Authors: Prof. Dr. Johnson Francis, MD, DM, FACC, FRCP Edin, FRCP London Tags: Cardiology MCQ DM / DNB Cardiology Entrance Source Type: blogs
Gold standard for cardiac allograft rejection – Cardiology MCQ
Gold standard for detection of cardiac allograft rejection:
HLA Antibody estimation
Signs of heart failure
Endomyocardial biopsy
ECG
Echocardiography
Please post your answer as a comment below.
Correct answer will be published on: Jan 4, 2018 @ 21:20 (Source: Cardiophile MD)
Source: Cardiophile MD - January 2, 2018 Category: Cardiology Authors: Prof. Dr. Johnson Francis, MD, DM, FACC, FRCP Edin, FRCP London Tags: Cardiology MCQ DM / DNB Cardiology Entrance Source Type: blogs
When the Nurse Becomes the Patient
While nurses have a great deal of experience treating and caring for patients, unforeseen circumstances will occasionally cause the tables to turn, giving the nurse the chance to be a patient. This became my personal reality just last week. Friday, Bloody FridayOn a recent Friday afternoon, I was doing my usual workout at a local gym where I can be found pretty much every other day most weeks of the year. Cardio, weightlifting, various machines, balance exercises, and resistance training all figure in my personalized routine. Early in my workout, I was using thick rubber tubes for resistance training. These bunge...
Source: Digital Doorway - July 17, 2017 Category: Nursing Tags: nurse nurses nursing Source Type: blogs
Fight Aging! Newsletter, June 26th 2017
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more.
This content is...
Source: Fight Aging! - June 25, 2017 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Altering Relative Macrophage Population Numbers to Enhance Nerve Regeneration
This study suggests that biasing the infiltrating inflammatory/immune cellular milieu after injury toward a proregenerative population creates a permissive environment for repair. This approach is a shift from the current modes of clinical and laboratory methods for nerve repair, which potentially opens an alternative paradigm to stimulate endogenous peripheral nerve repair.
Link: https://doi.org/10.1073/pnas.1705757114 (Source: Fight Aging!)
Source: Fight Aging! - June 22, 2017 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
A Combination Cell and Gene Therapy Repairs Severe Bone Fractures
The progress in various approaches to gene therapy over the past decade has succeeded in reducing cost and increasing reliability. This has reached the point at which researchers can afford, from the point of view of both time and funding, to begin to combine gene therapies with other areas of medicine under development. In particular, reliable gene therapies targeting the controlling switches and dials of cell growth and regeneration should be a way to greatly improve the effectiveness of cell therapies and other, similar forms of regenerative medicine. The research reported below is a good example of the type, in which s...
Source: Fight Aging! - June 20, 2017 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
