Janssen Announces Results from Phase 3 MAIA Study Showing Significant Overall Survival Benefits for Treatment with DARZALEX ® (daratumumab) in Patients with Newly Diagnosed Multiple Myeloma Who are Transplant Ineligible
Raritan, N.J., June 12, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced overall survival (OS) results from the Phase 3 MAIA (NCT02252172) study showing the addition of DARZALEX® (daratumumab) to lenalidomide and dexamethasone (D-Rd) resulted in a statistically significant survival benefit over lenalidomide and dexamethasone (Rd) alone in patients with newly diagnosed multiple myeloma (NDMM) who were ineligible for autologous stem cell transplant (ASCT) and were treated to progression.[1] These data were featured in the European Hematology Association (EHA) 2021 Virtual Press Briefing and w...
Source: Johnson and Johnson - June 12, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

South Africa: Blood Donation Saves Lives but Few South Africans Are Regular Donors
[The Conversation Africa] Blood donation is a vital therapy for a number of life threatening conditions. South Africa needs around 810,000 units of blood every year. People needing blood transfusions include accident victims, those with anaemia and patients undergoing surgery. But less than 1% of South Africans are active blood donors, which means regular shortages of supply. Glenda Mary Davison, a medical scientist with a special interest in haematological malignancy, immunology and inflammation, unpacks the blood donation process (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - June 11, 2021 Category: African Health Source Type: news

Covid US: Blood donations ARE safe amid pandemic as NIH finds transfusion has just 0.001% risk
You can safely give - or receive - blood without worrying about giving someone COVID, according to new research. This is good news for the thousands of patients who need blood transfusions. (Source: the Mail online | Health)
Source: the Mail online | Health - June 1, 2021 Category: Consumer Health News Source Type: news

Janssen Highlights Commitment to Advancing Transformative Innovations in Oncology with Scientific Updates from Deep, Diverse Pipeline and Portfolio at ASCO and EHA Virtual Scientific Programs
June 1, 2021 (RARITAN, N.J.) – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today that more than 30 company-sponsored studies, including six oral presentations, will be featured during the 2021 American Society of Clinical Oncology (ASCO) Annual Meeting, June 4-8. Janssen presentations will include new data and updates for both approved and investigational therapeutics that are being studied for the treatment of various solid tumors and blood cancers. Immediately following ASCO, additional data will be featured during the European Hematology Association (EHA) Virtual Congress, June 9-17. A comp...
Source: Johnson and Johnson - June 1, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Updated Data Demonstrate Significant Improvement in Hematologic Complete Response with DARZALEX FASPRO ® (daratumumab and hyaluronidase-fihj) in Patients with Newly Diagnosed Light Chain (AL) Amyloidosis
RARITAN, N.J., May 26, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced updated results from the Phase 3 ANDROMEDA study, which evaluated DARZALEX FASPRO® (daratumumab and hyaluronidase-fihj) for the treatment of patients with newly diagnosed light chain (AL) amyloidosis, a rare blood cell disorder associated with the deterioration of vital organs, most notably the heart, kidneys and liver.[1] Longer-term results from a median follow-up of 20.3 months showed rates of hematologic complete response (hemCR) remained significantly higher in patients treated with DARZALEX FASPRO® in combi...
Source: Johnson and Johnson - May 26, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

UCLA Health clinic helps mom heal after near-death birth experience
Marisa Peters, a 38-year-old mom of three, expected the delivery of her third child to be ordinary and uneventful, just like the births of her two other children. But right after her water broke at Ronald Reagan UCLA Medical Center on Feb. 6, 2019, she became quickly aware that this delivery would be very different.The first sign was a high fever that escalated rapidly. Then she developed an infection and began experiencing full-body convulsions, which were followed by a painful singular contraction that lasted for one hour. During this time, the baby ’s heart rate dipped, but she was lucky to catch a small window of tim...
Source: UCLA Newsroom: Health Sciences - May 26, 2021 Category: Universities & Medical Training Source Type: news

How West African Leaders Can Tackle Youth and Gender Inequities
Women informal cross-border traders. Credit: Trevor Davies/IPSBy Ifeanyi Nsofor, Adaeze Oreh, and John Lazame TindabilMay 6 2021 (IPS) Recently, both Republics of Benin and Chad held their 2021 national elections. These countries are among thirteen countries on the continent billed to elect new political leaders in 2021 alone. This is a good opportunity to improve conditions on the continent. Indeed, the COVID-19 pandemic has magnified other issues on the continent like youth unemployment that better leadership could help improve. These are three ways West African leaders can better help their nations at this time of CO...
Source: IPS Inter Press Service - Health - May 6, 2021 Category: International Medicine & Public Health Authors: Ifeanyi Nsofor, Adaeze Oreh, and John Lazame Tindabil Tags: Africa Gender Global Governance Headlines Health Poverty & SDGs Source Type: news

Blood transfusions in cats: A precious resource requiring a considered approach
(SAGE) Blood transfusions are a common procedure in medical practice in which donated blood is used to replace blood lost to injury or surgery or to treat serious medical conditions. The procedure is not performed as routinely in the treatment of pet cats - but, as in people, can be lifesaving. The availability of donors has been a limitation in primary care veterinary practice, but with the growth of blood banks providing greater access to feline blood, the procedure is likely to become more commonplace. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - April 26, 2021 Category: International Medicine & Public Health Source Type: news

Kenya: Bungoma County Breaks Ground for New Blood Bank Centre
[Nation] Residents of Bungoma and the wider Western region are set to benefit after the county government started the construction of a 10.8 million blood transfusion centre. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - April 23, 2021 Category: African Health Source Type: news

Massive transfusion prediction in patients with multiple trauma by decision tree: a retrospective analysis - Wei L, Chenggao W, Juan Z, Aiping L.
Early initial massive transfusion protocol and blood transfusion can reduce patient mortality, however accurately identifying the risk of massive transfusion (MT) remains a major challenge in severe trauma patient therapy. We retrospectively analyzed clini... (Source: SafetyLit)
Source: SafetyLit - April 23, 2021 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Uganda: Relief As Namutumba Hospital Starts Blood Transfusion Services
[Monitor] Residents of Namutumba have reason to smile as the district referral hospital starts blood transfusion services. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - March 15, 2021 Category: African Health Source Type: news

Kenya: Meru Sets Up 1,000-Unit Blood Bank at County Referral Hospital
[Nation] The Meru county government, in conjunction with the Kenya National Blood Transfusion Service (KNBTS), has established a 1,000-unit capacity blood bank at the Meru Referral Hospital. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - February 17, 2021 Category: African Health Source Type: news

Cancer Treatment Centers of America-Philadelphia establishes bloodless surgery program
The program is designed for cancer patients seeking medical care without receiving a blood transfusion or blood products. (Source: bizjournals.com Health Care:Physician Practices headlines)
Source: bizjournals.com Health Care:Physician Practices headlines - February 5, 2021 Category: American Health Authors: John George Source Type: news

DARZALEX FASPRO ® (daratumumab and hyaluronidase-fihj) Becomes the First FDA-Approved Treatment for Patients with Newly Diagnosed Light Chain (AL) Amyloidosis
January 15, 2021 (HORSHAM, Pa.) – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today the U.S. Food and Drug Administration (FDA) approval of DARZALEX FASPRO® (daratumumab and hyaluronidase-fihj), a subcutaneous formulation of daratumumab, in combination with bortezomib, cyclophosphamide and dexamethasone (D-VCd) for the treatment of adult patients with newly diagnosed light chain (AL) amyloidosis.[1] DARZALEX FASPRO® is the first and only FDA-approved treatment for patients with this blood cell disorder that is associated with the production of an abnormal protein, which leads to the deterior...
Source: Johnson and Johnson - January 16, 2021 Category: Pharmaceuticals Tags: Our Company Source Type: news

Consumer Health: The lifesaving gift of blood donation
January is National Blood Donor Month, which makes this a good time to learn more about blood donation. Each year, millions of people need a blood transfusion, and the need knows no season. Some may need blood during surgery. Others depend on it after an accident or because they have a disease that requires blood [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - January 15, 2021 Category: Databases & Libraries Source Type: news