Haemophilia can be cured through 'miracle' therapy
University College London researchers say a one-off gene therapy blood transfusion could stop people with haemophilia having to take weekly injections to manage the rare condition. (Source: the Mail online | Health)
Source: the Mail online | Health - July 21, 2022 Category: Consumer Health News Source Type: news

Belfast Trust: Refrigeration issues cause loss of blood stocks
The loss comes as the Blood Transfusion service calls on eligible donors to come forward to donate. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - July 14, 2022 Category: Consumer Health News Source Type: news

What are Potential Problems with Placental Abnormalities?
Discussion “The placenta is a unique organ that sits at the interface of, and facilitates nearly all interactions between, maternal and fetal physiology. It is the sole source of oxygen and nutrition for the fetus, and provides a protective barrier against external insults. The placenta is also a highly adaptable organ that is capable of showing a wide range of pathological changes in response to various maternal and fetal factors and stressors.” The placenta has 3 layers: the amnion (fetal side), the chorion, and decidua (maternal side). In addition to making observations about the maternal and fetal sides, co...
Source: PediatricEducation.org - June 27, 2022 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Rwanda: Rwanda Looks to Meet Blood Transfusion Demand By 2025
[New Times] Christian Mfashingabo, 25, had always wanted to donate blood but didn't have adequate information until last year when a campaign for blood donation happened at his school. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - June 14, 2022 Category: African Health Source Type: news

Janssen Presents Updated Data at EHA for Teclistamab in Patients with Relapsed or Refractory Multiple Myeloma
June 10, 2022 (VIENNA) – The Janssen Pharmaceutical Companies of Johnson & Johnson announced updated efficacy and safety results from the teclistamab cohort of the Phase 1b TriMM-2 study (NCT04108195). Teclistamab, an investigational, off-the-shelf, T-cell redirecting bispecific antibody targeting B-cell maturation antigen (BCMA) is being studied in combination with DARZALEX FASPRO® (daratumumab and hyaluronidase-fihj) in patients with relapsed or refractory multiple myeloma (RRMM) who have received three or more prior lines of therapy.1 Patients in the study, including a high proportion with prior anti-CD38 exposur...
Source: Johnson and Johnson - June 10, 2022 Category: Pharmaceuticals Tags: Innovation Source Type: news

Janssen Presents Updated Results Evaluating First-in-Class GPRC5D Bispecific Antibody Talquetamab in Heavily Pretreated Patients with Multiple Myeloma
June 10, 2022 (VIENNA) – The Janssen Pharmaceutical Companies of Johnson & Johnson announced updated results from the Phase 1 MonumenTAL-1 first-in-human dose-escalation study of talquetamab (NCT03399799), an investigational, off-the-shelf, T cell redirecting bispecific antibody targeting both GPRC5D, a novel multiple myeloma target, and CD3 on T cells.1 Results from the study showed encouraging responses in heavily pretreated patients with relapsed or refractory multiple myeloma (RRMM) who received talquetamab at the recommended subcutaneous Phase 2 dose (RP2D) administered weekly (QW) or every two weeks (Q2W).2 The...
Source: Johnson and Johnson - June 10, 2022 Category: Pharmaceuticals Tags: Innovation Source Type: news

Updated Data for Janssen ’s Bispecific Teclistamab Suggest Continued Deep and Durable Responses in the Treatment of Patients with Relapsed or Refractory Multiple Myeloma
CHICAGO, ILLINOIS, June 5, 2022 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced updated efficacy and safety results from the teclistamab Phase 1/2 MajesTEC-1 study. Teclistamab is an investigational, off-the-shelf, T-cell redirecting bispecific antibody targeting B-cell maturation antigen (BCMA), which is being studied in patients with relapsed or refractory multiple myeloma (RRMM) who have received three or more prior lines of therapy.1 The data were featured as part of an oral session during the 2022 American Society of Clinical Oncology (ASCO) Annual Meeting. Additional poster presentations f...
Source: Johnson and Johnson - June 5, 2022 Category: Pharmaceuticals Tags: Innovation Source Type: news

Janssen to Highlight Science, Innovation and Advances in Robust Oncology Portfolio and Pipeline Through More Than 60 Data Presentations at ASCO and EHA
RARITAN, N.J., May 31, 2022 — The Janssen Pharmaceutical Companies of Johnson & Johnson announced today that new research and data from its robust oncology portfolio and pipeline of investigational therapies will be presented at the 2022 American Society of Clinical Oncology (ASCO) Annual Meeting, taking place June 3-7 in Chicago, and the European Hematology Association (EHA) 2022 Congress taking place in Vienna, Austria, June 9-12. More than 60 presentations from company-sponsored studies across the two congresses, including 14 oral presentations, will feature new data and updates for both approved and investigation...
Source: Johnson and Johnson - May 31, 2022 Category: Pharmaceuticals Source Type: news

Malawi: CDH Investment Bank Invests U.S.$2,461 Towards Procurement of Blood Bank Fridge for MBTS
[Nyasa Times] In its efforts to boost access to blood transfusions for hard-to-reach areas across the country, Malawi Blood Transfusion Services (MBTS) is on a drive to place blood bank fridges in district hospitals that have several other health centres sorrounding it. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - April 26, 2022 Category: African Health Source Type: news

Prehospital Blood Transfusion for Civilian Trauma? Prehospital Blood Transfusion for Civilian Trauma?
This debate presents the pros and cons of prehospital blood transfusion, which is routine in the treatment of military trauma patients but remains controversial for civilians.Anesthesia & Analgesia (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - April 15, 2022 Category: Surgery Tags: Anesthesiology Journal Article Source Type: news

First-in-Class Drug Thwarts Hemolytic Anemia in Adults With PK Deficiency
(MedPage Today) -- Treatment with mitapivat (Pyrukynd) increased hemoglobin levels and decreased hemolysis in patients with pyruvate kinase (PK) deficiency who did not require regular blood transfusions, the randomized ACTIVATE trial showed. For... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - April 14, 2022 Category: Hematology Source Type: news

Kids With Cancer in Ukraine Take Shelter, Wait for Evacuation Kids With Cancer in Ukraine Take Shelter, Wait for Evacuation
At Kyiv Regional Oncology Center, some kids ' blood counts grew so low, and supplies became so sparse, that doctors started blood transfusions from parents to their kids.WebMD Health News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - March 1, 2022 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Consumer Health: Blood donation saves lives; are you a donor?
January is National Blood Donor Month, which makes this a good time to become a blood donor. Nearly 16 million blood components are transfused each year in the U.S., according to the American Red Cross. Daily needs include 29,000 units of red blood cells, 5,000 units of platelets and 6,500 units of plasma. People need a blood transfusion for many reasons. Some may need blood during surgery. Others depend on it after an accident or because they… (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - January 19, 2022 Category: Databases & Libraries Source Type: news

Is it safe to use lower blood counts as a trigger for blood transfusion?
Tuesday, January 4, 2022 (Source: Cochrane News and Events)
Source: Cochrane News and Events - January 4, 2022 Category: Information Technology Authors: Muriah Umoquit Source Type: news

Mayo Clinic Q & amp;A podcast: Urgent need for blood donation
Blood donations typically drop off around the holidays, making National Blood Donor Month in January and important time to share the message about saving lives by giving blood. The COVID-19 pandemic also has affected blood donations. "The COVID-19 pandemic has really had an adverse effect on us recruiting and collecting blood donors in general," says Dr. Justin Juskewitch, associate medical director of Mayo Clinic Blood Donor Services.  Millions of people need blood transfusions each year.… (Source: Mayo Clinic Minnesota News)
Source: Mayo Clinic Minnesota News - January 3, 2022 Category: Hospital Management Source Type: news