Microfluidic Photoreactor for Neonatal Jaundice
Researchers at the Oregon State University College of Engineering have developed a microfluidic photoreactor that is intended to treat severe cases of neonatal jaundice. Jaundice is caused by an excess of a pigment called bilirubin, which can be difficult to excrete due to underlying conditions in many neonates. In severe cases, newborns may need multiple blood transfusions, which is resource and labor intensive, and can come with risks. This system could help avoid such procedures, and involves passing the blood of the newborn through a microfluidic device, where an LED helps to break the bilirubin down into more easily e...
Source: Medgadget - December 8, 2021 Category: Medical Devices Authors: Conn Hastings Tags: Medicine Pediatrics Source Type: blogs
Does your health monitor have device bias?
In recent years, there’s been a veritable explosion in the number and type of health monitoring devices available in smartphones and fitness apps.
Your smartphone is likely tracking the number of steps you take, how far and fast you walk, and how many flights of stairs you climb each day. Some phones log sleep, heart rate, how much energy you’re burning, and even “gait health” (how often are both feet on the ground? how even are your steps?). And, of course, nonphone wearables and fitness gadgets are available, such as devices to measure your heart rhythm, blood pressure, or oxygen levels. The accuracy of these dev...
Source: Harvard Health Blog - February 19, 2021 Category: Consumer Health News Authors: Robert H. Shmerling, MD Tags: Children's Health Health care disparities Health trends Healthy Aging Heart Health Source Type: blogs
Newborn jaundice: What parents need to know
Most newborn babies turn at least a little bit yellow. Known as jaundice, this condition is a very common and usually normal part of the newborn period. But in some very rare cases it can lead to (or be a sign of) a more serious problem. That’s why parents need to know about it.
What causes jaundice?
The yellow color of newborn jaundice is caused by high levels of a substance called bilirubin in the blood. Bilirubin mostly comes from the breakdown of red blood cells. It gets processed in the liver to make it easier for the body to get rid of through the urine and stool.
Newborn livers need some time to get up and running...
Source: Harvard Health Blog - February 4, 2021 Category: Consumer Health News Authors: Claire McCarthy, MD Tags: Children's Health Parenting Screening Source Type: blogs
COVID-19 anosmia: Unmasking a new dark “twist”
A 4-day-old term, formula-fed male infant with an uncomplicated prenatal course and no ABO set up or other identified cause of excessive jaundice was admitted to the hospital for phototherapy treatment of hyperbilirubinemia with a peak bilirubin of 19.5. He had an uneventful hospital course and was discharged on day 6 of life. On day […]Find jobs at Careers by KevinMD.com. Search thousands of physician, PA, NP, and CRNA jobs now. Learn more. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - October 14, 2020 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/michael-d-schwartz" rel="tag" > Michael D. Schwartz, MD < /a > < /span > Tags: Conditions COVID-19 coronavirus Emergency Medicine Infectious Disease Pediatrics Source Type: blogs
Clinical characteristics and predictors of outcomes of hospitalised patients with COVID-19 in a London NHS trust: a retrospective cohort study
This report is one of the first studies to describe the characteristics and predictors of outcome for hospitalised Covid-19 patients in the UK. It finds that older age, male sex and admission hypoxia, thrombocytopenia, renal failure, hypoalbuminaemia and raised bilirubin are associated with increased odds of death. Ethnic minority groups were over-represented in the cohort and, compared to whites, people of black ethnicity may be at increased odds of mortality.ReportMore detail (Source: Health Management Specialist Library)
Source: Health Management Specialist Library - May 4, 2020 Category: UK Health Authors: The King ' s Fund Library Tags: Equality and diversity Local authorities, public health and health inequalities Source Type: blogs
RAPIDPoint 500e Blood Gas Analyzer FDA Cleared to Help Ventilated Patients
To help address the COVID-19 emergency that’s taking over emergency rooms and intensive care units in the United States, the FDA has cleared the RAPIDPoint 500e blood gas system from Siemens Healthineers.
The device uses the company’s Integri-sense technology to provide results on blood gas, electrolyte, metabolite, CO-oximetry, and neonatal bilirubin. This is important during the crisis, as mechanically ventilated patients require regular blood gas testing to maintain proper ventilator settings and to adjust any other therapies being delivered.
The system already has the CE Mark, clearing its use in...
Source: Medgadget - March 31, 2020 Category: Medical Devices Authors: Medgadget Editors Tags: Anesthesiology Cardiology Critical Care Diagnostics Emergency Medicine Pediatrics Source Type: blogs
MELD and MELD-XI scores
Model for End-Stage Liver Disease (MELD) score is a logarithmic function of creatinine, total bilirubin and International Hospitalized Ratio (INR):
MELD = 9.57(logeCreatinine) + 3.78(logeBilirubin) + 11.21(logeINR) + 6.43.
MELD score was originally developed to assess prognosis in patients undergoing transjugular intrahepatic portosystemic shunts (TIPS) for cirrhosis liver [1]. Later MELD score has been used in cardiovascular conditions like patients undergoing left ventricular assist device (LVAD) placement to operative transfusion requirements, morbidity, and mortality [2].
An important limitation for using MELD sc...
Source: Cardiophile MD - December 15, 2019 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: Cardiology Source Type: blogs
Fight Aging! Newsletter, November 18th 2019
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter,
please visit:
https://www.fightaging.org/newsletter/
Longevity Industry Consulting Services
Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - November 17, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Poor Results from an Initial Human Trial of Nicotinamide Mononucleotide
Mitochondria are the power plants of the cell, responsible for packaging energy store molecules that power cellular processes. NAD+ is an essential metabolite for mitochondrial function, but levels decline with age. The proximate causes of this decline are fairly well mapped, and involve insufficient resources in a variety of pathways for synthesis or recycling of NAD+. The deeper reasons are poorly understood, however, meaning how these pathway issues emerge from the underlying molecular damage to cells and tissues that causes aging. Ways to force an increase in NAD+ levels have been shown to improve mitochondrial functio...
Source: Fight Aging! - November 11, 2019 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
The Three Ps of Pyloric Stenosis
The back story of pyloric stenosis is fascinating. It is a relatively minor surgical condition today, but the disease had a mortality of 100 percent before 1904, when only five operative cases were known to have been performed in the United States. The dying process was slow and painful, and parents watched their infants slowly starve to death.The pyloromyotomy procedure currently used to treat pyloric stenosis was introduced by Conrad Ramstedt, MD, in 1911 at the Children's Hospital of Munster, and is still called the Ramstedt procedure. Before surgical management was introduced for this gastric outlet obstruction, mul...
Source: M2E Too! Mellick's Multimedia EduBlog - October 1, 2019 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs
A Troublesome Cup of Tea
A 45-year-old woman presented to the emergency department with nausea and vomiting. Her symptoms had started seven days earlier and steadily worsened. She reported generalized abdominal pain and distention and that her eyes appeared yellow.The patient had no past medical history, took no medications, and said she did not drink or use drugs. Her history showed that she had been drinking an herbal preparation every day for the past five months to ameliorate her heavy menstrual periods.The patient had mild right upper quadrant tenderness but no distention, rebound, or guarding. Her lungs were clear, and her heart rate and rhy...
Source: The Tox Cave - July 1, 2019 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs
Pros and Cons of Delayed Cord Clamping
Delayed cord clamping allows extra time, usually one to three minutes, between the clamping and separation of the umbilical cord from the baby, until pulsations in the umbilical cord have ceased or the placenta is delivered. This allows the remaining stem cell-rich blood from the placenta to be transferred to the baby after birth (up to one-third of the baby’s total blood volume).
Delayed cord clamping at birth has proven to benefit both baby and mom. Some studies show that the added blood volume in babies (especially in pre-term babies) increases their red blood count by 60%. Not only does this help prevent iron deficie...
Source: Cord Blood News - January 29, 2019 Category: Perinatology & Neonatology Authors: Maze Cord Blood Tags: Cord Blood pregnancy stem cells Source Type: blogs
In Search of Intra-Aero-Bili-ty
By MATTHEW HOLT
Another one of my favorites, although this one is much more recent than those published so far–dating back to only March 2015. It was the written version of a talk I gave in September 2014 following the birth of my son Aero on August 26, 2014. So if we are discussing birthdays (and re-posting classics as, yes, it’s still THCB’s 15th birthday week!) we might as well have one that is literally about the confluence of a birthday and the state of health IT, health business, care for the underserved and much more!
Today is the kick-off of the vendor-fest that is HIMSS. Late last week on THCB, ...
Source: The Health Care Blog - August 16, 2018 Category: Consumer Health News Authors: matthew holt Tags: Health 2.0 Matthew Holt Tech Epic Interoperability Nadine Burke Sutter Source Type: blogs
Tropical Travel Trouble 009 Humongous HIV Extravaganza
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog
aka Tropical Travel Trouble 009
The diagnosis of HIV is no longer fatal and the term AIDS is becoming less frequent. In many countries, people with HIV are living longer than those with diabetes. This post will hopefully teach the basics of a complex disease and demystify some of the potential diseases you need to consider in those who are severely immunosuppressed. While trying to be comprehensive this post can not be exhaustive (as you can imagine any patient with a low ...
Source: Life in the Fast Lane - July 7, 2018 Category: Emergency Medicine Authors: Amanda McConnell Tags: Clinical Cases Tropical Medicine AIDS art cryptococcoma cryptococcus HIV HIV1 HIV2 PEP PrEP TB toxoplasma tuberculoma Source Type: blogs
Tropical Travel Trouble 007 Mega Malaria Extravaganza
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog
aka Tropical Travel Trouble 007
When you think tropical medicine, malaria has to be near the top. It can be fairly complex and fortunately treatment has become a lot simpler. This post is designed to walk you through the basic principals with links to more in depth teaching if your niche is travel medicine, laboratory diagnostics or management of severe or cerebral malaria. If you stubbled on this post while drinking a cup of tea or sitting on the throne and want a few basi...
Source: Life in the Fast Lane - April 5, 2018 Category: Emergency Medicine Authors: Neil Long Tags: Clinical Cases Tropical Medicine malaria Plasmodium plasmodium falciparum plasmodium knowles plasmodium malariae plasmodium ovale plasmodium vivax Source Type: blogs
