Hemolysis question
I see LDH/haptoglobin ordered a lot in ICUs and was wondering how much of this is truly necessary. Does normal bilirubin pretty much rule out significant hemolysis or is there additional utility in ordering LDH/haptoglobin? (Source: Student Doctor Network)
Source: Student Doctor Network - May 24, 2023 Category: Universities & Medical Training Authors: Student3322 Tags: Hematology / Oncology Source Type: forums
Question from EM - how do you differentiate liver disease vs hemolysis labs?
Hello IM friends, I am in EM and have a question that I think better fits your expertise. I've had several chronic alcoholic patients come in with a lab pattern of anemia, low platelets, and elevated bilirubin. I know this can be expected for some cirrhotics, but it is also the pattern that might prompt consideration of hemolysis/MAHA. What do you do in these situations to differentiate between the two?
I'm sure that sending a full hemolysis panel and smear would help guide us, but we...
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Source: Student Doctor Network - October 24, 2022 Category: Universities & Medical Training Authors: EMgordo Tags: Internal Medicine and IM Subspecialties Source Type: forums
Does conjugated bilirubin cause jaundice too?
I understand unconjugated bilirubin can cause jaundice. Can conjugated bilirubin also jaundice? Much of the literature I'm finding simply states "bilirubin". Thanks for the help. (Source: Student Doctor Network)
Source: Student Doctor Network - January 11, 2017 Category: Universities & Medical Training Authors: yanks26dmb Source Type: forums
Bilirubin in the Neonate... (normal or alarming?)
OK so I have been confused on this for a while
I have heard that a newborn should never be jaundiced... and yet I have heard that it is normal.
Reading MTB2 it says this
Transient Hyperbilirubinemia
"Over 60% of all newborn infants are jaundiced. This is due to the infant's spleen removing RBCs carrying HgbF. This results in a physiological release of hemoglobin and in turn a rise in bilirubin"
Then...
Pathologic Jaundice in the Newborn...
Bilirubin in the Neonate... (normal or alarming?) (Source: Student Doctor Network)
Source: Student Doctor Network - August 30, 2016 Category: Universities & Medical Training Authors: Delacroix22 Source Type: forums
urinary bilirubin
In hemolysis due to inherited disorders, the level of
1)UCB: increase, decrease or normal?
2) conjugated bilirubin: increase, decrease or normal?
3) urinary bilirubin: increase, decrease or normal? (Source: Student Doctor Network)
Source: Student Doctor Network - August 20, 2016 Category: Universities & Medical Training Authors: enhancers Source Type: forums
NBME 16 the unsolvables
Answer and please explain if you did get them right >.<|||
3) 28. 27 y/o with hodgkins gets bone marrow transplant. two weeks after transplant, develops an erythematous, maculopapular rash, diarrhea, and elevated serum liver enzymes and bilirubin. no evidence of infection or drug reaction found. what's the mechanism of these symptoms? It’s graft vs host so answer should be c right?
a-donor macrophages secreting cytokines and affecting host cells
b-donor plasma cells ellaborating...
NBME 16 the unsolvables (Source: Student Doctor Network)
Source: Student Doctor Network - July 19, 2016 Category: Universities & Medical Training Authors: fatwalletuab Source Type: forums
