Liver Stiffness Measurement-Based Approach for HBV Liver Stiffness Measurement-Based Approach for HBV
Decline of liver stiffness from baseline after 1 year of antiviral therapy for HBV infection may reflect remission of liver inflammation and fibrosis.Journal of Viral Hepatitis (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 3, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news
HBV Treatment Fails to Meet Global Targets (CME/CE)
(MedPage Today) -- Only 5% of hepatitis B patients received antiviral therapy in 2016 (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - March 26, 2018 Category: Primary Care Source Type: news
Treatment To Prevent Hepatitis C Recurrence After Liver Transplantation
In a clinical trial, researchers found that antiviral therapy prior to a liver transplant can prevent hepatitis C recurrence in some patients. (Source: NIDDK News)
Source: NIDDK News - March 15, 2018 Category: Endocrinology Source Type: news
Hepatitis C Virus Clearance in Older Adults Hepatitis C Virus Clearance in Older Adults
Does HCV clearance with direct-acting antiviral therapy improve outcomes in individuals aged 80 and older--even in the face of severe liver disease and multiple comorbidities?Journal of the American Geriatrics Society (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 21, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news
Shortening Duration of Therapy With DAAs for HCV Genotype 1 Shortening Duration of Therapy With DAAs for HCV Genotype 1
Can direct-acting antiviral therapy for hepatitis C genotype 1 be reduced to less than the current standard of 12 weeks without compromising outcomes?Journal of Viral Hepatitis (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 9, 2017 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news
Sofosbuvir Safe, Effective for HCV in Those With CKD Sofosbuvir Safe, Effective for HCV in Those With CKD
Sofosbuvir-based antiviral therapy cured hepatitis C virus infection in more than 80% of patients with chronic kidney disease, a retrospective cohort study found.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - September 15, 2017 Category: Consumer Health News Tags: Gastroenterology News Source Type: news
Treating a little-known virus, CMV, to combat hearing loss in children
(University of Utah Health) A National Institutes of Health-supported nationwide clinical trial will test a novel approach to combat hearing loss in children infected by a relatively unknown virus, cytomegalovirus (CMV). The University of Utah Health-led study will determine whether antiviral therapy can halt progressive hearing loss in children with a confirmed CMV infection. CMV is the leading non-genetic cause of hearing loss, contributing from 6 to 30 percent of childhood cases. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - September 14, 2017 Category: Infectious Diseases Source Type: news
Antiviral Therapy in Patients With Influenza Antiviral Therapy in Patients With Influenza
Which patients should receive antiviral therapy for influenza, and what are the currently available options?U.S. Pharmacist (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 22, 2017 Category: Consumer Health News Tags: Infectious Diseases Journal Article Source Type: news
Subcirrhotic Liver Stiffness Cuts HCC Risk in Hepatitis B
Achievement of subcirrhotic range of liver stiffness with antiviral therapy reduces HCC risk (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - July 10, 2017 Category: Cancer & Oncology Tags: Gastroenterology, Infections, Internal Medicine, Oncology, Journal, Source Type: news
Antiviral therapy is effective in fighting hepatitis C | Letters
The Cochrane analysis casting doubt on this life-saving therapy is flawed and may deter patients from seeking it, say clinicians and scientistsWe are clinicians and scientists who have studied and treated patients with chronic hepatitis C virus infection over many years and patient groups that represent those affected by hepatitis C. We write in response to your article on the effectiveness of antiviral therapy (Hepatitis ‘wonder drug’ may be clinically ineffective, say experts, 9 June). The Cochrane review that you highlight analysed clinical trials, which are by nature short term, where the sole purpose was to evalua...
Source: Guardian Unlimited Science - June 13, 2017 Category: Science Authors: Letters Tags: Hepatitis C Health Pharmaceuticals industry Medical research Drugs Business Science UK news Society Source Type: news
The Potential Role of Polymerase Chain Reaction in Diagnosis of Neonatal Herpes Simplex Virus Infection: Is Viral Culture Outdated?
Even in the era of effective antiviral therapy, neonatal herpes simplex viral infection causes significant morbidity and mortality in newborns. Prompt diagnosis is the cornerstone of treatment of these infants. Outside and inside the neonatal clinical practice, polymerase chain reaction (PCR) is replacing culture as a method of facilitating a speedy diagnosis of herpes simplex virus infection. New pediatric guidelines call for testing of high-risk asymptomatic infants, and thus, many more surface cultures and PCRs are being performed. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - June 6, 2017 Category: Microbiology Authors: Nicole L. Samies, Swathi M. Gowtham Source Type: news
IRE1{alpha} promotes viral infection by conferring resistance to apoptosis
The unfolded protein response (UPR) is an ancient cellular pathway that detects and alleviates protein-folding stresses. The UPR components X-box binding protein 1 (XBP1) and inositol-requiring enzyme 1α (IRE1α) promote type I interferon (IFN) responses. We found that Xbp1-deficient mouse embryonic fibroblasts and macrophages had impaired antiviral resistance. However, this was not because of a defect in type I IFN responses but rather an inability of Xbp1-deficient cells to undergo viral-induced apoptosis. The ability to undergo apoptosis limited infection in wild-type cells. Xbp1-deficient cells were generall...
Source: Signal Transduction Knowledge Environment - June 6, 2017 Category: Science Authors: Fink, S. L., Jayewickreme, T. R., Molony, R. D., Iwawaki, T., Landis, C. S., Lindenbach, B. D., Iwasaki, A. Tags: STKE Research Articles Source Type: news
Risk of HBV Reactivation in Patients on Antivirals for HCV Risk of HBV Reactivation in Patients on Antivirals for HCV
Is there a clinically relevant risk of HBV reactivation during direct-acting antiviral therapy for HCV with an interferon-free regimen?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 23, 2017 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news
HBIG Plus Antivirals May Prevent HBV Reinfection After Transplant HBIG Plus Antivirals May Prevent HBV Reinfection After Transplant
A very short course of hepatitis B immunoglobulin (HBIG) after liver transplantation, along with long-term antiviral therapy, may prevent hepatitis B virus (HBV) reinfection, a retrospective study suggests.Reuters Health Information (Source: Medscape Transplantation Headlines)
Source: Medscape Transplantation Headlines - May 22, 2017 Category: Transplant Surgery Tags: Transplantation News Source Type: news
Prevalence and Impact of Steatohepatitis in HBV Patients Prevalence and Impact of Steatohepatitis in HBV Patients
This study assessed the prevalence of steatohepatitis in chronic HBV-infected patients, its risk factors, and its correlation with liver fibrosis and response to antiviral therapy.Liver International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 9, 2017 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news
