Janssen to Highlight Science, Innovation and Advances in Robust Oncology Portfolio and Pipeline Through More Than 60 Data Presentations at ASCO and EHA
RARITAN, N.J., May 31, 2022 — The Janssen Pharmaceutical Companies of Johnson & Johnson announced today that new research and data from its robust oncology portfolio and pipeline of investigational therapies will be presented at the 2022 American Society of Clinical Oncology (ASCO) Annual Meeting, taking place June 3-7 in Chicago, and the European Hematology Association (EHA) 2022 Congress taking place in Vienna, Austria, June 9-12. More than 60 presentations from company-sponsored studies across the two congresses, including 14 oral presentations, will feature new data and updates for both approved and investigation...
Source: Johnson and Johnson - May 31, 2022 Category: Pharmaceuticals Source Type: news
U.S. FDA Approves CARVYKTI ™ (ciltacabtagene autoleucel), Janssen’s First Cell Therapy, a BCMA-Directed CAR-T Immunotherapy for the Treatment of Patients with Relapsed or Refractory Multiple Myeloma
HORSHAM, Pa., February 28, 2022 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today the U.S. Food and Drug Administration (FDA) has approved CARVYKTI™ (ciltacabtagene autoleucel; cilta-cel) for the treatment of adults with relapsed or refractory multiple myeloma (RRMM) after four or more prior lines of therapy, including a proteasome inhibitor, an immunomodulatory agent, and an anti-CD38 monoclonal antibody.1 The approval is based on data from the pivotal CARTITUDE-1 study, which included patients who had received a median of six prior treatment regimens (range, 3-18), and had previously rec...
Source: Johnson and Johnson - March 1, 2022 Category: Pharmaceuticals Tags: Innovation Source Type: news
Tomato concentrate could help reduce chronic intestinal inflammation associated with HIV
New UCLA-led research in mice suggests that adding a certain type of tomato concentrate to the diet can reduce the intestinal inflammation that is associated with HIV. Left untreated, intestinal inflammation can accelerate arterial disease, which in turn can lead to heart attack and stroke.The findings provide clues to how the altered intestinal tract affects disease-causing inflammation in people with chronic HIV infection, suggesting that targeting the inflamed intestinal wall may be a novel way to prevent the systemic inflammation that persists even when antiviral therapy is effective in controlling a person ’s HIV.Th...
Source: UCLA Newsroom: Health Sciences - January 11, 2022 Category: Universities & Medical Training Source Type: news
Why We Are Developing a Patent-Free COVID Antiviral Therapy Why We Are Developing a Patent-Free COVID Antiviral Therapy
During global health crises such as pandemics, drug discovery should be publicly funded and open, with no research secrets locked away.Knowable Magazine (Source: Medscape Critical Care Headlines)
Source: Medscape Critical Care Headlines - September 29, 2021 Category: Intensive Care Tags: Infectious Diseases Commentary Source Type: news
Synthetic SARS-CoV-2 could be used as antiviral therapy for COVID-19: Study
The cell is then tricked into reproducing the virus's genetic material and packaging it into virions, particles which burst from the cell and go off to infect other cells. (Source: The Economic Times)
Source: The Economic Times - July 13, 2021 Category: Consumer Health News Source Type: news
India's Hetero says COVID-19 drug reduces hospitalisations in late-stage trial
Molnupiravir is an antiviral therapy Merck& Co is developing with Ridgeback Biotherapeutics for the treatment of non-hospitalised COVID-19 patients. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - July 9, 2021 Category: Pharmaceuticals Source Type: news
Liver Transplant Outcomes Improving for US Patients With HIV/HCV Liver Transplant Outcomes Improving for US Patients With HIV/HCV
Hepatitis C virus (HCV) infection no longer confers worse patient survival in the era of direct-acting antiviral therapy, but the population remains underserved.Medscape Medical News (Source: Medscape Transplantation Headlines)
Source: Medscape Transplantation Headlines - May 28, 2021 Category: Transplant Surgery Tags: Gastroenterology News Source Type: news
City of Hope and Griffith University develop direct-acting antiviral to treat COVID-19
(City of Hope) An international team of scientists have developed an experimental direct-acting antiviral therapy to treat COVID-19. Traditional antivirals reduce symptoms and help people recover earlier. This next-generation antiviral approach used gene-silencing RNA technology called siRNA (small-interfering RNA) to attack the virus' genome directly, which stops the virus from replicating, as well as lipid nanoparticles designed at Griffith University and City of Hope to deliver the siRNA to the lungs, the critical site of infection. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - May 18, 2021 Category: Biology Source Type: news
HCV Antivirals Associated With Reduced Risk of CVD Events HCV Antivirals Associated With Reduced Risk of CVD Events
Hepatitis C virus infection has been associated with a greater risk of cardiovascular disease. Might antiviral therapy reduce the risk?Journal of Viral Hepatitis (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 9, 2021 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news
Liver Disease Progression in Persistent vs. Eradicated HCV Liver Disease Progression in Persistent vs. Eradicated HCV
This study investigated the long-term prognosis of liver disease in patients with HCV eradication after antiviral therapy versus those with persistent HCV infection.Journal of Viral Hepatitis (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 15, 2021 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news
Cell-free DNA and Risk of HCC in Treated HBV Patients Cell-free DNA and Risk of HCC in Treated HBV Patients
This study investigated whether different species of serum circulating cfDNA may be involved in the process of hepatocarcinogenesis in chronic HBV patients receiving oral antiviral therapy.Journal of Viral Hepatitis (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 11, 2021 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news
New combination antiviral therapy against coronavirus
(University of Malaga) SARS-CoV-2 genome is three times larger than influenza genome. Both consist of NRA molecules that mutate when replicate. It is essential to know its mutant spectrum, in other words, its 'fingerprints', to achieve an appropriate treatment that reduces its infectivity -the capacity of pathogens to invade organisms and cause infections-, since its composition of variants could determine how infection would develop in each patient. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 12, 2021 Category: International Medicine & Public Health Source Type: news
T cells linked to myelin implicated in MS-like disease in monkeys
(Oregon Health& Science University) Scientists have uncovered new clues implicating a type of herpes virus as the cause of a central nervous system disease in monkeys that's similar to multiple sclerosis in people. By linking two specific T cells to the loss of myelin, scientists say the new study opens the possibility of developing an antiviral therapy that could be especially useful for newly diagnosed cases of multiple sclerosis. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 15, 2021 Category: International Medicine & Public Health Source Type: news
Care Quality and Outcomes for Chronic HBV in the HCV DAA Era Care Quality and Outcomes for Chronic HBV in the HCV DAA Era
Has overall quality of care for HBV significantly improved in the era of widespread HCV direct-acting antiviral therapy?Journal of Viral Hepatitis (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - October 16, 2020 Category: Infectious Diseases Tags: Gastroenterology Journal Article Source Type: news
The Role of C-Section in Mother-to-child Transmission of HBV The Role of C-Section in Mother-to-child Transmission of HBV
Does cesarean section and nonbreastfeeding prevent mother-to-child transmission in HBV-positive mothers who did not receive antiviral therapy during pregnancy?Journal of Viral Hepatitis (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 9, 2020 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news
