NextGen COVID-19 Antibodies Destroy Spike Protein
Researchers at the Garvan Institute of Medical Research in Australia have developed a new generation of antibodies to treat COVID-19. So far, the antibodies have been shown to neutralize several of the viral variants behind COVID-19, and the researchers hope that they will form an effective treatment for at-risk patients. Previously developed antibody treatments for COVID-19 have been rendered largely useless as the virus has mutated. Such antibodies have focused on binding to the most obvious site on the viral spike protein, the ACE2 receptor binding site, but their efficacy in destroying the virus has waned with new vira...
Source: Medgadget - February 23, 2023 Category: Medical Devices Authors: Conn Hastings Tags: Medicine Public Health Source Type: blogs
The Future of COVID-19 Therapies and Vaccines
Against all odds and breaking development records, we now have several approved COVID-19 vaccines rolling out worldwide. No need for DIY vaccines; these research-backed shots have repeatedly been shown to prevent SARS-CoV-2 infections and its spread. In May, following new evidence of efficacy in children, the FDA further approved administering the Pfizer / BioNTech COVID-19 vaccine to children aged between 12 and 15 years. Before, only those aged 16 and up could get the vaccine but vaccinating more children will be key to achieving herd immunity and ending the pandemic.
With such a promising outlook of available vaccine...
Source: The Medical Futurist - June 1, 2021 Category: Information Technology Authors: Pranavsingh Dhunnoo Tags: Covid-19 Digital Health Research therapy Fauci cdc vaccine pfizer Moderna SARS SARS-CoV-2 trials Duke Human Vaccine Institute Altimmune Nigel McMillan Source Type: blogs
Fight Aging! Newsletter, September 14th 2020
This study is the first to provide a direct link between this inflammation and plaque development - by way of IFITM3.
Scientists know that the production of IFITM3 starts in response to activation of the immune system by invading viruses and bacteria. These observations, combined with the new findings that IFITM3 directly contributes to plaque formation, suggest that viral and bacterial infections could increase the risk of Alzheimer's disease development. Indeed, researchers found that the level of IFITM3 in human brain samples correlated with levels of certain viral infections as well as with gamma-secretase activ...
Source: Fight Aging! - September 13, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Kimer Med Founded to Develop the DRACO Antiviral Strategy
Today's good news is that a biotech startup, Kimer Med, has been founded to develop the DRACO approach to defeating viral infections. Those of us who have been following developments in antiviral technologies that might be applied to persistent infections relevant to aging, such as cytomegalovirus (CMV) and other herpesviruses, may recall a burst of interest in DRACO some years ago, particularly the research crowdfunding efforts in 2015 and 2016.
DRACO (Double-stranded RNA Activated Caspase Oligomerizer) works by selectively killing cells that exhibit one of the distinctive signs of viral replication. This replicati...
Source: Fight Aging! - September 7, 2020 Category: Research Authors: Reason Tags: Healthy Life Extension Community Source Type: blogs
Planning for Future Pandemics Including Smallpox Outbreaks: Interview with Dr. Phil Gomez, CEO, SIGA Technologies
The COVID-19 pandemic has had significant global consequences, with healthcare systems stretched to their limits, a growing death toll, and economic devastation as economies came grinding to a halt.
The pandemic
and its aftereffects will be with us for some time to come, but this isn’t the
first pandemic humanity has weathered, and it won’t be the last. Given accelerating
advances in medical technology, there is plenty to discuss in terms of how we
can be better prepared for the next infectious disease event.
While COVID-19 is widely thought to have arisen naturally through transmission between an animal and a hu...
Source: Medgadget - May 27, 2020 Category: Medical Devices Authors: Conn Hastings Tags: Exclusive Medicine Public Health Source Type: blogs
Fight Aging! Newsletter, November 25th 2019
This study demonstrates for the first time that senescent cells secrete functional LTs, significantly contributing to the LTs pool known to cause or exacerbate idiopathic pulmonary fibrosis.
Against Senolytics
https://www.fightaging.org/archives/2019/11/against-senolytics/
There is no consensus in science that is so strong as to have no heretics. So here we have an interview with a naysayer on the matter of senolytic treatments, who argues that the loss of senescent cells in aged tissues will cause more harm to long-term health than the damage they will do by remaining. To be clear, I think this to be a...
Source: Fight Aging! - November 24, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Vaccination and Antiviral Therapies Targeting CMV as an Approach to Reducing Immunosenescence
Today's open access paper discusses possible approaches to the treatment of immunosenescence, the age-related decline in effectiveness of the immune system. Unfortunately it is largely a tour of compensatory treatments, ways to force the cells of the immune system into greater or more useful activity without addressing any of the underlying causes of immunosenescence. Many of these methodologies have serious side-effects, are disruptive of normal immune function and overall health, and cannot be applied for the long term. Checkpoint inhibition, or the delivery of recombinant IL-7, for example, both of which are used as sho...
Source: Fight Aging! - November 20, 2019 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Cracking the Herpes Encephalitis Code | Causes, Symptoms and Treatment
Conclusion
Herpes encephalitis may rule your body but don't allow the infection to take over your brain. Herpes encephalitis is suppressible and so its symptoms if managed with great attention.
Antiviral drugs such as Zovirax, acyclovir, Valacyclovir are some of the prominently used drugs in suppressing therapy of herpes infection.
You are counseled to see your GP as soon as the very onset of any symptoms described above.You've read Cracking the Herpes Encephalitis Code | Causes, Symptoms and Treatment, originally posted on Pick the Brain | Motivation and Self Improvement. If you've enjoyed this, please visit our site f...
Source: PickTheBrain | Motivation and Self Improvement - June 5, 2019 Category: Consumer Health News Authors: anilkumar Tags: health and fitness Herpes Encephalitis symptoms of herpes encephalitis Source Type: blogs
Baby boomers and hepatitis C: What ’s the connection?
Hepatitis C is a viral infection that is spread through contact with infected blood. Hepatitis C infection can be short-term (acute) or long-term (chronic). Most people with acute hepatitis C eventually develop chronic hepatitis C.
Hepatitis C usually does not cause symptoms, which is why most people with hepatitis C don’t know that they are infected. Left untreated, hepatitis C can lead to cirrhosis, liver cancer, and liver failure.
Why screen baby boomers for hepatitis C?
Why are we recommending screening of adults in the baby boomer generation? To understand this, it’s worth reviewing how we got here.
In 1998, t...
Source: Harvard Health Blog - May 1, 2019 Category: Consumer Health News Authors: Raymond Chung, MD Tags: Health Healthy Aging Infectious diseases Screening Source Type: blogs
Tropical Travel Trouble 008 Total TB Extravaganza
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog
aka Tropical Travel Trouble 008
Peer Reviewer Dr McBride ID physician, Wisconsin
TB affects 1/3rd of the population and one patient dies every 20 seconds from TB. Without treatment 50% of pulmonary TB patients will be dead in 5 years. In low to middle income countries both TB and HIV can be ubiquitous, poor compliance can lead to drug resistance and malnourished infants are highly susceptible. TB can be very complex and this post will hopefully give you the backbone to TB m...
Source: Life in the Fast Lane - June 16, 2018 Category: Emergency Medicine Authors: Neil Long Tags: Clinical Cases Tropical Medicine Genexpert meningitis TB TB meningitis Tuberculosis Source Type: blogs
A physician makes the case for some routine labs
Many medical organizations have recently been promoting focused and individualized lab testing for routine screening or when pursuing a diagnosis. Research has shown that the “shotgun” approach to lab testing usually leads to further invasive testing which has not been proven to significantly alter morbidity or mortality.
Additionally, tests rely on pre-test probabilities and can have false-positive or negative results and even lead to adverse events from the follow-up testing. In response to this, medical organizations have created many resources to help educate and guide physicians from over-testing. The American Col...
Source: Kevin, M.D. - Medical Weblog - May 1, 2018 Category: General Medicine Authors: < a href="https://www.kevinmd.com/blog/post-author/shmuel-golfeyz" rel="tag" > Shmuel Golfeyz, MD < /a > Tags: Conditions Gastroenterology Hospital-Based Medicine Primary Care Source Type: blogs
Funtabulously Frivolous Friday Five 228
LITFL • Life in the Fast Lane Medical Blog
LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog
Just when you thought your brain could unwind on a Friday, you realise that it would rather be challenged with some good old fashioned medical trivia FFFF…introducing Funtabulously Frivolous Friday Five 228.
Question 1
Who is the Berlin patient?
+ Reveal the Funtabulous Answer
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Timothy Ray Brown
Arguably the first person to be cured of HIV. There are other patients w...
Source: Life in the Fast Lane - March 2, 2018 Category: Emergency Medicine Authors: Neil Long Tags: Frivolous Friday Five Berlin patient bullet virus HIV PCP pneumocystis carinii Pneumocystis jiroveci Queen Square Hammer rabies Reflex hammer reflexes Taylor Hammer The Ramones Timothy Ray Brown Troemner hammer Source Type: blogs
Fight Aging! Newsletter, May 22nd 2017
In this study, researchers analysed data of millions of British patients between 1995 and 2015 to see if this claim held true. They tracked people who were obese at the start of the study, defined as people with a body mass index (BMI) of 30 or more, who had no evidence of heart disease, high blood pressure, high cholesterol or diabetes at this point. They found these people who were obese but "metabolically healthy" were at higher risk of developing heart disease, strokes and heart failure than people of normal weight.
No such thing as 'fat but fit', major study finds
Several studies in the past have sug...
Source: Fight Aging! - May 21, 2017 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Researchers Generate Improved Lung Tissue Organoids
In tissue engineering this is the age of organoids: while the challenge of generating a blood vessel network sufficient to grow large tissue sections is not yet solved, researchers are nonetheless establishing the diverse set of methodologies needed to grow functional organ tissue from a cell sample. The recipe is different for every tissue type, and there are many forms of tissue in the body. The resulting small tissue sections are known as organoids. At this time organoids are largely used to speed up further research, but for some tissue types there is the potential to produce therapies based on transplantation of multi...
Source: Fight Aging! - May 16, 2017 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
