Antimicrobial Resistance Clinical Trials This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Testing the effects of mass drug administration of azithromycin on mortality and other outcomes among 1 –11-month-old infants in Mali (LAKANA): study protocol for a cluster-randomized, placebo-controlled, double-blinded, parallel-group, three-arm clinical trial
DiscussionIf LAKANA provides evidence in support of a positive mortality benefit resulting from azithromycin MDA, it will significantly contribute to the options for successfully promoting child survival in Mali, and elsewhere in sub-Saharan Africa.Trial registrationClinicalTrials.gov NCT04424511. Registered on 11 June 2020. (Source: Trials)
Source: Trials - January 3, 2023 Category: Research Source Type: clinical trials

Ocular Rosacea microBiome Study (ORBS) —sub-microbial versus antibiotic dosing of doxycycline versus placebo in treatment of symptomatic ocular rosacea: study protocol for a parallel-arm randomized clinical trial
DiscussionThese results will enhance our understanding of the overall systemic impact of long-term systemic sub-microbial antibiotic dosing for the treatment of chronic recurrent ocular inflammatory diseases.Trial registrationThis trial was registered on ClinicalTrials.org (NCT05296837) on March 22, 2022. (Source: Trials)
Source: Trials - December 20, 2022 Category: Research Source Type: clinical trials

ASEPTIC: primary antibiotic prophylaxis using co-trimoxazole to prevent SpontanEous bacterial PeritoniTIs in Cirrhosis —study protocol for an interventional randomised controlled trial
DiscussionThis trial will investigate the efficacy, safety, and cost-effectiveness of co-trimoxazole for patients with liver cirrhosis and ascites to determine whether this strategy improves clinical outcomes. Given there are no treatments that improve survival in decompensated cirrhosis outside of liver transplant, if the trial has a positive outcome, we anticipate widespread adoption of primary antibiotic prophylaxis.Trial registrationClinicalTrials.govNCT043955365. Registered on 18 April 2020. Research ethical approval was granted by the Research Ethics Committee (South Central – Oxford B; REC 19/SC/0311) and the Medi...
Source: Trials - September 27, 2022 Category: Research Source Type: clinical trials

Investigating Point-of-care Diagnostics for Sexually Transmitted Infections and Antimicrobial Resistance in Primary Care in Zimbabwe
Conditions: Sexually Transmitted Infection; Chlamydia; Gonorrhea; Trichomoniasis; Syphilis; Hepatitis B; HIV Infections; Pregnancy; Sexually Transmitted Diseases Intervention: Diagnostic Test: Point-of-care STI testing Sponsors: London School of Hygiene and Tropical Medicine; Biomedical Research and Training Institute Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 15, 2022 Category: Research Source Type: clinical trials