Functional and molecular 3D mapping of angiosarcoma tumor using non-invasive laser speckle, hyperspectral, and photoacoustic imaging
CONCLUSIONS: We demonstrate the different physiological parameters that can be obtained with the different techniques and how these can be combined to provide detailed 3D maps of the functional and molecular properties of tumors useful in preoperative assessment.PMID:38591750 | DOI:10.1080/01676830.2024.2331718 (Source: Orbit)
Source: Orbit - April 9, 2024 Category: Opthalmology Authors: Magne Stridh Ulf Dahlstrand Magdalena Naumovska Karl Engelsberg Bodil Gesslein Rafi Sheikh Aboma Merdasa Malin Malmsj ö Source Type: research

Functional and molecular 3D mapping of angiosarcoma tumor using non-invasive laser speckle, hyperspectral, and photoacoustic imaging
CONCLUSIONS: We demonstrate the different physiological parameters that can be obtained with the different techniques and how these can be combined to provide detailed 3D maps of the functional and molecular properties of tumors useful in preoperative assessment.PMID:38591750 | DOI:10.1080/01676830.2024.2331718 (Source: Orbit)
Source: Orbit - April 9, 2024 Category: Opthalmology Authors: Magne Stridh Ulf Dahlstrand Magdalena Naumovska Karl Engelsberg Bodil Gesslein Rafi Sheikh Aboma Merdasa Malin Malmsj ö Source Type: research

Functional and molecular 3D mapping of angiosarcoma tumor using non-invasive laser speckle, hyperspectral, and photoacoustic imaging
CONCLUSIONS: We demonstrate the different physiological parameters that can be obtained with the different techniques and how these can be combined to provide detailed 3D maps of the functional and molecular properties of tumors useful in preoperative assessment.PMID:38591750 | DOI:10.1080/01676830.2024.2331718 (Source: Orbit)
Source: Orbit - April 9, 2024 Category: Opthalmology Authors: Magne Stridh Ulf Dahlstrand Magdalena Naumovska Karl Engelsberg Bodil Gesslein Rafi Sheikh Aboma Merdasa Malin Malmsj ö Source Type: research

Functional and molecular 3D mapping of angiosarcoma tumor using non-invasive laser speckle, hyperspectral, and photoacoustic imaging
CONCLUSIONS: We demonstrate the different physiological parameters that can be obtained with the different techniques and how these can be combined to provide detailed 3D maps of the functional and molecular properties of tumors useful in preoperative assessment.PMID:38591750 | DOI:10.1080/01676830.2024.2331718 (Source: Orbit)
Source: Orbit - April 9, 2024 Category: Opthalmology Authors: Magne Stridh Ulf Dahlstrand Magdalena Naumovska Karl Engelsberg Bodil Gesslein Rafi Sheikh Aboma Merdasa Malin Malmsj ö Source Type: research

Functional and molecular 3D mapping of angiosarcoma tumor using non-invasive laser speckle, hyperspectral, and photoacoustic imaging
CONCLUSIONS: We demonstrate the different physiological parameters that can be obtained with the different techniques and how these can be combined to provide detailed 3D maps of the functional and molecular properties of tumors useful in preoperative assessment.PMID:38591750 | DOI:10.1080/01676830.2024.2331718 (Source: Orbit)
Source: Orbit - April 9, 2024 Category: Opthalmology Authors: Magne Stridh Ulf Dahlstrand Magdalena Naumovska Karl Engelsberg Bodil Gesslein Rafi Sheikh Aboma Merdasa Malin Malmsj ö Source Type: research

Functional and molecular 3D mapping of angiosarcoma tumor using non-invasive laser speckle, hyperspectral, and photoacoustic imaging
CONCLUSIONS: We demonstrate the different physiological parameters that can be obtained with the different techniques and how these can be combined to provide detailed 3D maps of the functional and molecular properties of tumors useful in preoperative assessment.PMID:38591750 | DOI:10.1080/01676830.2024.2331718 (Source: Orbit)
Source: Orbit - April 9, 2024 Category: Opthalmology Authors: Magne Stridh Ulf Dahlstrand Magdalena Naumovska Karl Engelsberg Bodil Gesslein Rafi Sheikh Aboma Merdasa Malin Malmsj ö Source Type: research

Functional and molecular 3D mapping of angiosarcoma tumor using non-invasive laser speckle, hyperspectral, and photoacoustic imaging
CONCLUSIONS: We demonstrate the different physiological parameters that can be obtained with the different techniques and how these can be combined to provide detailed 3D maps of the functional and molecular properties of tumors useful in preoperative assessment.PMID:38591750 | DOI:10.1080/01676830.2024.2331718 (Source: Orbit)
Source: Orbit - April 9, 2024 Category: Opthalmology Authors: Magne Stridh Ulf Dahlstrand Magdalena Naumovska Karl Engelsberg Bodil Gesslein Rafi Sheikh Aboma Merdasa Malin Malmsj ö Source Type: research

Radiotherapy combined with anti-PD-1 and TKI for primary cardiac angiosarcoma considering the joint assessment of TLSs and PD-L1: a case report
Primary cardiac angiosarcoma(PCA) has a low incidence rate and poor prognosis. Currently, no unified clinical treatment standards are available. (Source: Journal of Cardiothoracic Surgery)
Source: Journal of Cardiothoracic Surgery - April 9, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Shuzhe Deng, Xinxin Yang, Lin He, Qian Zhang, Chunbo Zhao and Hongxue Meng Tags: Case Report Source Type: research

Paediatric hepatic angiosarcoma with consumptive hypothyroidism —an important diagnostic pitfall to avoid during evaluation of hepatic vascular tumours
We present a case of hepatic angiosarcoma in a 20-month-old girl, associated with consumptive hypothyroidism and, as a result, initially misdiagnosed as infantile hepatic haemangioma. Radiologists should be aware that consumptive hypothyroidism is not a reliable feature to use in  excluding paediatric hepatic angiosarcoma. Biopsy should be performed in patients older than 1 year of age or with atypical imaging features.Graphical abstract (Source: Pediatric Radiology)
Source: Pediatric Radiology - April 6, 2024 Category: Radiology Source Type: research

Strongyloides stercoralis infection masquerading as malignant ascites in a case of angiosarcoma
We present a case of a 56-year-old male with a known case of angiosarcoma liver with massive ascites and low-grade fever. He was clinically diagnosed as having malignant ascites and was planned for chemotherapy. During therapeutic cum diagnostic ascitic tap, cell block sections revealed the presence of cross sections of nematode S. stercoralis gravid uterus with eggs. Later, stool for ova and cysts also revealed multiple larval forms of the nematode. S. stercoralis hyperinfection is often accompanied by sepsis or meningitis with enteric organisms. Patient was started on tab. ivermectin 12 mg once a day for two days (in the...
Source: Indian Journal of Pathology and Microbiology - April 2, 2024 Category: Pathology Authors: Gurpreet K Walia Ramanjit S Akal Abhishek Singh Jayanth Pothedar Source Type: research

Strongyloides stercoralis infection masquerading as malignant ascites in a case of angiosarcoma
We present a case of a 56-year-old male with a known case of angiosarcoma liver with massive ascites and low-grade fever. He was clinically diagnosed as having malignant ascites and was planned for chemotherapy. During therapeutic cum diagnostic ascitic tap, cell block sections revealed the presence of cross sections of nematode S. stercoralis gravid uterus with eggs. Later, stool for ova and cysts also revealed multiple larval forms of the nematode. S. stercoralis hyperinfection is often accompanied by sepsis or meningitis with enteric organisms. Patient was started on tab. ivermectin 12 mg once a day for two days (in the...
Source: Indian Journal of Pathology and Microbiology - April 2, 2024 Category: Pathology Authors: Gurpreet K Walia Ramanjit S Akal Abhishek Singh Jayanth Pothedar Source Type: research

Strongyloides stercoralis infection masquerading as malignant ascites in a case of angiosarcoma
We present a case of a 56-year-old male with a known case of angiosarcoma liver with massive ascites and low-grade fever. He was clinically diagnosed as having malignant ascites and was planned for chemotherapy. During therapeutic cum diagnostic ascitic tap, cell block sections revealed the presence of cross sections of nematode S. stercoralis gravid uterus with eggs. Later, stool for ova and cysts also revealed multiple larval forms of the nematode. S. stercoralis hyperinfection is often accompanied by sepsis or meningitis with enteric organisms. Patient was started on tab. ivermectin 12 mg once a day for two days (in the...
Source: Indian Journal of Pathology and Microbiology - April 2, 2024 Category: Pathology Authors: Gurpreet K Walia Ramanjit S Akal Abhishek Singh Jayanth Pothedar Source Type: research

Strongyloides stercoralis infection masquerading as malignant ascites in a case of angiosarcoma
We present a case of a 56-year-old male with a known case of angiosarcoma liver with massive ascites and low-grade fever. He was clinically diagnosed as having malignant ascites and was planned for chemotherapy. During therapeutic cum diagnostic ascitic tap, cell block sections revealed the presence of cross sections of nematode S. stercoralis gravid uterus with eggs. Later, stool for ova and cysts also revealed multiple larval forms of the nematode. S. stercoralis hyperinfection is often accompanied by sepsis or meningitis with enteric organisms. Patient was started on tab. ivermectin 12 mg once a day for two days (in the...
Source: Indian Journal of Pathology and Microbiology - April 2, 2024 Category: Pathology Authors: Gurpreet K Walia Ramanjit S Akal Abhishek Singh Jayanth Pothedar Source Type: research

Strongyloides stercoralis infection masquerading as malignant ascites in a case of angiosarcoma
We present a case of a 56-year-old male with a known case of angiosarcoma liver with massive ascites and low-grade fever. He was clinically diagnosed as having malignant ascites and was planned for chemotherapy. During therapeutic cum diagnostic ascitic tap, cell block sections revealed the presence of cross sections of nematode S. stercoralis gravid uterus with eggs. Later, stool for ova and cysts also revealed multiple larval forms of the nematode. S. stercoralis hyperinfection is often accompanied by sepsis or meningitis with enteric organisms. Patient was started on tab. ivermectin 12 mg once a day for two days (in the...
Source: Indian Journal of Pathology and Microbiology - April 2, 2024 Category: Pathology Authors: Gurpreet K Walia Ramanjit S Akal Abhishek Singh Jayanth Pothedar Source Type: research

Chemo-senolytic therapeutic potential against angiosarcoma
Angiosarcoma is an aggressive soft-tissue sarcoma with a poor prognosis. Chemotherapy for this cancer typically employs paclitaxel, a taxane (genotoxic drug), although it has a limited effect owing to chemoresistance to prolonged treatment. Here, we examine an alternative angiosarcoma treatment approach that combines chemotherapeutic and senolytic agents. We find that the chemotherapeutic drugs cisplatin and paclitaxel efficiently induce senescence in angiosarcoma cells. Subsequent treatment with the senolytic agent ABT-263 eliminates senescent cells by activating the apoptotic pathway. (Source: Journal of Investigative Dermatology)
Source: Journal of Investigative Dermatology - April 1, 2024 Category: Dermatology Authors: Xuebing Wang, Claire Yik-Lok Chung, Ai Yoshioka, Shinya Hashimoto, Haruki Jimbo, Hideki Tanizawa, Shinya Ohta, Takeshi Fukumoto, Ken-ichi Noma Tags: Original Article Source Type: research