Assessing the Real-World Effectiveness of Immunizations for Respiratory Syncytial Virus
This Viewpoint discusses recommendations from the US Centers for Disease Control and Prevention for newly licensed immunizations for respiratory syncytial virus in infants, children with high-risk conditions, and older adults. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - April 11, 2024 Category: General Medicine Source Type: research

Health Systems Science Integration in Graduate Medical Education: A Pathway to Quintuple Aim Success for Independent Practice
The United States continues to outspend other high-income countries on health care without improving health outcomes.1 This understanding has been a launching pad for changes to health care structure and processes and movement towards achieving the Institution of Healthcare Improvement (IHI) Quintuple Aim.2 While health systems evolve in the approaches to health care delivery, education on these fundamental skills for the professional medical community has lagged. The American Medical Association (AMA) instituted health systems science (HSS) in 2013 as a third pillar of medical education, bringing national attention to the...
Source: The American Journal of Medicine - April 11, 2024 Category: General Medicine Authors: Sonia Bharel, Brian McGillen, Rachel Salas, Dharmini Shah Pandya Tags: AAIM Perspectives Source Type: research

Including Pregnant and Lactating Women in Clinical Research
This Viewpoint summarizes a new report from the National Academies of Sciences, Engineering, and Medicine that encourages the inclusion of pregnant and lactating individuals in clinical research. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - April 10, 2024 Category: General Medicine Source Type: research

Consortium Authors and Nonauthor Collaborators Added
The Original Investigation titled “Development of a Definition of Postacute Sequelae of SARS-CoV-2 Infection,” published in the June 13, 2023, issue of JAMA, has been corrected to include additional consortium authors and nonauthor collaborator names in a supplement. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - April 10, 2024 Category: General Medicine Source Type: research

Uterine Fibroids
This JAMA Insights in the Women ’s Health series discusses the incidence, diagnosis, and treatment of uterine fibroids. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - April 10, 2024 Category: General Medicine Source Type: research

Manufacturer Payments to Cardiologists and Use of Devices
This study examines whether payments from a left ventricular assist device manufacturer to cardiologists performing percutaneous coronary intervention were associated with any use of the devices. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - April 10, 2024 Category: General Medicine Source Type: research

Sternotomy
Armour I built over slow weeks in my first trimester (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - April 10, 2024 Category: General Medicine Source Type: research

Complications and Surgeon Health: Resources for individuals and institutions
This article underscores the importance of such educational initiatives in the mid-career phase, proposing strategies to promote surgeon health, and psychological safety. It advocates for utilizing Morbidity and Mortality conferences as platforms for peer support, learning from 'near miss' events, and encourages at least annual department-wide discussions to raise awareness and normalize the emotional challenges faced by surgeons. Furthermore, it highlights the role of formal peer support programs, acceptance and commitment therapy, and resilience training as vital tools for promoting surgeon well-being. Resources from var...
Source: Urologic Oncology - April 9, 2024 Category: Urology & Nephrology Authors: Gagan Prakash Chloe E Peters Gina Badalato Lindsay A Hampson Jay D Raman Aditya Bagrodia Source Type: research

Complications and Surgeon Health: Resources for individuals and institutions
This article underscores the importance of such educational initiatives in the mid-career phase, proposing strategies to promote surgeon health, and psychological safety. It advocates for utilizing Morbidity and Mortality conferences as platforms for peer support, learning from 'near miss' events, and encourages at least annual department-wide discussions to raise awareness and normalize the emotional challenges faced by surgeons. Furthermore, it highlights the role of formal peer support programs, acceptance and commitment therapy, and resilience training as vital tools for promoting surgeon well-being. Resources from var...
Source: Urologic Oncology - April 9, 2024 Category: Urology & Nephrology Authors: Gagan Prakash Chloe E Peters Gina Badalato Lindsay A Hampson Jay D Raman Aditya Bagrodia Source Type: research

Error in Conflict of Interest Disclosure Statements
In several JAMA articles published in 2022 and 2023, an incorrect institution was published in Dr Califf ’s conflict of interest disclosure statements: the Center for Policy Analysis on Trade and Health should have been listed as the Critical Path Institute. The articles have been corrected online. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - April 8, 2024 Category: General Medicine Source Type: research

Cardiac Function Before Sepsis and Clinical Outcomes
This cohort study characterizes heterogeneity in cardiac function prior to sepsis and describes associations with hospitalization outcomes and mortality. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - April 8, 2024 Category: General Medicine Source Type: research

Single Ascending and Multiple-Dose Trial of Zerlasiran, a Short Interfering RNA Targeting Lipoprotein(a)
This phase 1 randomized study assesses the safety and tolerability of zerlasiran, a short interfering RNA targeting hepatic synthesis of apolipoprotein(a), and its effects on serum concentrations of lipoprotein(a), in healthy participants and patients with stable atherosclerotic cardiovascular disease. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - April 8, 2024 Category: General Medicine Source Type: research

Systemic Lupus Erythematosus
This review summarizes current evidence regarding the diagnosis, treatment, and prognosis of systemic lupus erythematosus. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - April 8, 2024 Category: General Medicine Source Type: research

Data Checks Before Registering Study Protocols for Health Care Database Analyses
This Viewpoint discusses the challenges involved with secondary health care data collection vs primary data collection and provides a list of suggested data checks before registration of a study protocol using secondary data. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - April 8, 2024 Category: General Medicine Source Type: research

Clinical Benefit and Regulatory Outcomes of Cancer Drugs Receiving Accelerated Approval
This study aims to determine whether cancer drugs granted accelerated approval from the US Food and Drug Administration ultimately demonstrate clinical benefit and to evaluate the basis of conversion to regular approval. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - April 7, 2024 Category: General Medicine Source Type: research