[Antimicrobial effects of fentanyl and bupivacaine].
CONCLUSIONS: Addition of fentanyl to Local Anesthetics (LAs) is often preferred in regional anesthesia applications in today's practice owing especially to its effect on decreasing the local anesthetic dose and increasing analgesia quality and patient satisfaction. However, when the fact that fentanyl antagonized the antimicrobial effects of LAs in the studies is taken into account, it might be though that it contributes to an increase in infection complications. When the fact that fentanyl citrate, which was used in our study and included hydrochloric acid and sodium hydroxide as protective agents, broadened the antimicro...
Source: Revista Brasileira de Anestesiologia - August 22, 2020 Category: Anesthesiology Tags: Rev Bras Anestesiol Source Type: research
Contact Transfer Risk from Fentanyl-Contaminated RSDL ® Kit.
Contact Transfer Risk from Fentanyl-Contaminated RSDL® Kit.
Toxicol Lett. 2019 Nov 15;:
Authors: de Bruin-Hoegée M, de Koning MC, Cochrane L, Joosen MJA
Abstract
The RSDL® (Reactive Skin Decontamination Lotion) Kit contains a lotion-impregnated sponge extensively studied for the removal or neutralization of chemical warfare agents from skin. Pilot investigation of efficacy with industrial threat compounds noted that synthetic opioid fentanyl citrate was removed by the RSDL Kit but not chemically inactivated by the lotion. This implies that after use the RSDL Kit will contain in...
Source: Toxicology Letters - November 14, 2019 Category: Toxicology Authors: de Bruin-Hoegée M, de Koning MC, Cochrane L, Joosen MJA Tags: Toxicol Lett Source Type: research
[Quasi-experimental study of an intervention on the pharmacological management of non-oncological chronic pain in Primary Care].
CONCLUSIONS: The intervention reduced the number of patients with incidences, and this reduction was higher in the prospective cohort, confirming the efficacy of sending information about patients with incidences to their physicians. The incorporation of new treatments during the follow-up year was significant, so these interventions should be perpetuated over time.
PMID: 31727390 [PubMed - as supplied by publisher] (Source: Atencion Primaria)
Source: Atencion Primaria - November 10, 2019 Category: Primary Care Authors: García Vicente JA, Vedia Urgell C, Vallès Fernández R, Reina Rodríguez D, Rodoreda Noguerola S, Samper Bernal D Tags: Aten Primaria Source Type: research
H-Bonded anion –anion complexes in fentanyl citrate polymorphs and solvates
We report the experimental observation (X-ray characterization) of two types of anion –anion complexes (anion = dihydrogen citrate) stabilized by H-bonds that are observed in fentanyl citrate solvates. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Chem. Commun. latest articles)
Source: RSC - Chem. Commun. latest articles - December 6, 2018 Category: Chemistry Authors: Rafael Barbas Source Type: research
H-Bonded anion –anion complexes in fentanyl citrate polymorphs and solvates
We report the experimental observation (X-ray characterization) of two types of anion –anion complexes (anion = dihydrogen citrate) stabilized by H-bonds that are observed in fentanyl citrate solvates. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Chem. Commun. latest articles)
Source: RSC - Chem. Commun. latest articles - December 5, 2018 Category: Chemistry Authors: Rafael Barbas Source Type: research
H-Bonded anion-anion complexes in fentanyl citrate polymorphs and solvates.
Abstract
Herein we report the experimental observation (X-ray characterization) of two different binding modes in H-bonded anion-anion complexes (anion = citrate) in N-(1-(2-phenylethyl)-4-piperidinylium)-N-phenyl-propanamide-citrate (fentanyl citrate). High level DFT calculations indicate that both types of anion-anion complexes (one with two and the other with four H-bonds) are thermodynamically unstable but kinetically stable with respect to the isolated anions with activation barriers as high as 14 kcal mol-1.
PMID: 30516180 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - December 5, 2018 Category: Chemistry Authors: Barbas R, Prohens R, Bauzá A, Franconetti A, Frontera A Tags: Chem Commun (Camb) Source Type: research
H-bonded anion-anion complexes in fentanyl citrate polymorphs and solvates
Chem. Commun., 2018, Accepted Manuscript DOI: 10.1039/C8CC09028A, CommunicationRafael Barbas, Rafel Prohens, Antonio Bauza, Antonio Franconetti, Antonio Frontera Herein we report the experimental observation (X-ray characterization) of two different binding modes in H-bonded anion –anion complexes (anion = citrate) in N-(1-(2-Phenylethyl)-4-piperidinylium)-N-phenyl-propanamide-citrate (fentanyl citrate). High level DFT calculations indicate that... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Chem. Commun. latest articles)
Source: RSC - Chem. Commun. latest articles - November 27, 2018 Category: Chemistry Authors: Rafael Barbas Source Type: research
Evaluation of Intravenous Parecoxib Infusion Pump of Patient-Controlled Analgesia Compared to Fentanyl for Postoperative Pain Management in Laparoscopic Liver Resection.
CONCLUSIONS Use of the intravenous infusion parecoxib pump for patient-controlled analgesia provides superior analgesic efficacy and fewer adverse effects for patients after laparoscopic liver resection.
PMID: 30439866 [PubMed - in process] (Source: Medical Science Monitor)
Source: Medical Science Monitor - November 17, 2018 Category: Research Tags: Med Sci Monit Source Type: research
Intraoperative pectoral nerve block (Pec) for breast cancer surgery: A randomized controlled trial
Conclusion: Pec II block with ropivacaine delivered under vision reduced analgesic requirement and pain scores significantly. (Source: Journal of Anaesthesiology Clinical Pharmacology)
Source: Journal of Anaesthesiology Clinical Pharmacology - October 11, 2018 Category: Anesthesiology Authors: Mary Thomas Frenny A Philip Arun P Mathew KM Jagathnath Krishna Source Type: research
Trends in Prehospital Analgesia Administration by US Forces From 2007 Through 2016.
CONCLUSIONS: During the study period, rates of prehospital administration of IM morphine remained relatively stable while those for OTFC and ketamine both rose. These findings suggest that TCCC guidelines recommending the use of these agents had a material impact on prehospital analgesia patterns.
PMID: 30118637 [PubMed - as supplied by publisher] (Source: Prehospital Emergency Care)
Source: Prehospital Emergency Care - August 18, 2018 Category: Endocrinology Tags: Prehosp Emerg Care Source Type: research
A Survey of Wilderness Medicine Analgesia Practice Patterns
ConclusionsWilderness medicine practitioners prefer analgesic agents recommended by the WMS for the treatment of acute pain. Respondents most frequently preferred acetaminophen and NSAIDs. (Source: Wilderness and Environmental Medicine)
Source: Wilderness and Environmental Medicine - July 11, 2018 Category: Environmental Health Source Type: research
Pharmacokinetics of Fentanyl Sublingual Spray in Opioid-Na ïve Participants: Results of a Phase 1, Multiple Ascending Dose Study
ConclusionDose-dependent fentanyl pharmacokinetics following multiple doses of fentanyl sublingual spray were well characterized in an opioid-na ïve population.ClinicalTrials.gov identifierNCT02641340. (Source: Clinical Drug Investigation)
Source: Clinical Drug Investigation - June 16, 2018 Category: Drugs & Pharmacology Source Type: research
Pharmacokinetics of fentanyl citrate and norfentanyl in Holstein calves and effect of analytical performances on fentanyl parameter estimation
Journal of Veterinary Pharmacology and Therapeutics, EarlyView. (Source: Journal of Veterinary Pharmacology and Therapeutics)
Source: Journal of Veterinary Pharmacology and Therapeutics - March 30, 2018 Category: Veterinary Research Source Type: research
A Survey of Wilderness Medicine Analgesia Practice Patterns
Conclusions Wilderness medicine practitioners prefer analgesic agents recommended by the WMS for the treatment of acute pain. Respondents most frequently preferred acetaminophen and NSAIDs. (Source: Wilderness and Environmental Medicine)
Source: Wilderness and Environmental Medicine - March 23, 2018 Category: Environmental Health Source Type: research
