Contamination and health risk of pesticides in eight popular Chinese traditional medicines from Zhejiang Province
In this study, pesticides residual levels in crude and processing samples were assessed along with their health risks in Zhebawei primarily produced in Zhejiang Province. In total, the exceeded ratios of pesticides residual concentrations in above mentioned eight species were 15/23, 4/7, 26/70, 22/44, 10/19, 8/12, 7/15, and 0/2, respectively. No acute dietary intake health risks were found but the long-term risks from permethrin in S. Radix should be carefully considered, with all quotient values being higher than 2.1 for all groups between 7 and 70 years. Furthermore, the risks of total benzene hexachloride in T. Fritilla...
Source: Environmental Science and Pollution Research International - January 5, 2024 Category: Environmental Health Authors: Tingting Ma Xia Pan Tiantian Wang Yongming Luo Source Type: research

Evaluation of the knockdown resistance locus ( < em > kdr < /em > ) in < em > Anopheles stephensi < /em > (Diptera: Culicidae) in southeastern Iran
CONCLUSION: The current study revealed the presence of L1014F mutation for the first time in Iran. So, further monitoring of kdr mutations in the VGSC gene and resistance phenotypes should be performed.PMID:38174525 | DOI:10.4103/0972-9062.383648 (Source: Journal of Vector Borne Diseases)
Source: Journal of Vector Borne Diseases - January 4, 2024 Category: Infectious Diseases Authors: Ramtin Hajibeygi Seyed Zia Hejripour Nader Taghavi Hamzeh Shahali Saeed Zarei Majid Nouri Hadi Mirahmadi Seyed Mahdi Tabatabaie Rahmat Solgi Mohammad Darvishi Source Type: research

Retraction for Drali et al., “Detection of a Knockdown Resistance Mutation Associated with Permethrin Resistance in the Body Louse Pediculus humanus corporis by Use of Melting Curve Analysis Genotyping”
Journal of Clinical Microbiology, Ahead of Print. (Source: Journal of Clinical Microbiology)
Source: Journal of Clinical Microbiology - January 4, 2024 Category: Microbiology Source Type: research

Pyrethroid susceptibility reversal in < i > Aedes aegypti < /i > : A longitudinal study in Tapachula, Mexico
by Patricia Penilla-Navarro, Francisco Solis-Santoyo, Alma Lopez-Solis, Americo D. Rodriguez, Farah Vera-Maloof, Saul Lozano, Elsa Contreras-Mej ía, Geovanni Vázquez-Samayoa, Rene Torreblanca-Lopez, Rushika Perera, William C. Black IV, Karla Saavedra-Rodriguez Pyrethroid resistance inAedes aegypti has become widespread after almost two decades of frequent applications to reduce the transmission of mosquito-borne diseases. Because few insecticide classes are available for public health use, insecticide resistance management (IRM) is proposed as a strategy to retain their use. A key hypothesis of IRM assumes that negative...
Source: PLoS Neglected Tropical Diseases - January 2, 2024 Category: Tropical Medicine Authors: Patricia Penilla-Navarro Source Type: research

Molecules, Vol. 29, Pages 45: Magnetic Persimmon Leaf Composite: Preparation and Application in Magnetic Solid-Phase Extraction of Pesticides in Water Samples
This study introduces, for the first time, the preparation of Fe3O4/persimmon leaf magnetic biomass composites. The magnetic composites were employed in a magnetic solid-phase extraction method, coupled with gas chromatography-electron capture detection (GC-ECD), for the analysis of four pesticides (trifluralin, triadimefon, permethrin, and fenvalerate) in environmental water samples. The innovative magnetic persimmon leaf composites were synthesized by in situ generation of Fe3O4 nanoparticles through coprecipitation and loaded onto persimmon leaves. These composites exhibit superparamagnetism with a saturation magnetizat...
Source: Molecules - December 20, 2023 Category: Chemistry Authors: Yuyue Zang Na Hang Jiale Sui Senlin Duan Wanning Zhao Jing Tao Songqing Li Tags: Article Source Type: research

Comparison of topical 5% permethrin vs. 25% benzyl benzoate in treating scabies - A double-blinded, randomized controlled study
CONCLUSION: Topical permethrin demonstrated a lack of efficacy in the majority of cases whereas benzyl benzoate demonstrated an excellent cure rate and reasonable tolerability. Considering the reduced sensitivity of scabies mites to 5% permethrin, our results suggest that benzyl benzoate is an appropriate first-line therapy in the treatment of scabies.TRIAL REGISTRATION: drks.de, ID DRKS00031062.PMID:38112640 | DOI:10.1093/bjd/ljad501 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - December 19, 2023 Category: Dermatology Authors: Damian Meyersburg Magdalena Hoellwerth Matthias Brandlmaier Allesandra Handisurya Andreas Kaiser Christine Prodinger Johann W Bauer Source Type: research

Comparison of topical 5% permethrin vs. 25% benzyl benzoate in treating scabies - A double-blinded, randomized controlled study
CONCLUSION: Topical permethrin demonstrated a lack of efficacy in the majority of cases whereas benzyl benzoate demonstrated an excellent cure rate and reasonable tolerability. Considering the reduced sensitivity of scabies mites to 5% permethrin, our results suggest that benzyl benzoate is an appropriate first-line therapy in the treatment of scabies.TRIAL REGISTRATION: drks.de, ID DRKS00031062.PMID:38112640 | DOI:10.1093/bjd/ljad501 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - December 19, 2023 Category: Dermatology Authors: Damian Meyersburg Magdalena Hoellwerth Matthias Brandlmaier Allesandra Handisurya Andreas Kaiser Christine Prodinger Johann W Bauer Source Type: research

Adult Mosquito and Butterfly Exposure to Permethrin and Relative Risk Following ULV Sprays from a Truck-Mounted Sprayer
This study compared the risk of permethrin to adult mosquitoes and adult butterflies to assess the likelihood that the butterflies would be affected following such sprays. Permethrin toxicity values were determined for Aedes aegypti and Culex quinquefasciatus (LD50s of 81.1 and 166.3 ng/g dw, respectively) and then combined with published toxicity data in a species sensitivity distribution for comparison with published permethrin toxicity data for adult butterflies. The sensitivity distributions indicated adult butterflies and mosquitoes are similarly sensitive, meaning relative risk would be a function of exposure. Exposu...
Source: Archives of Environmental Contamination and Toxicology - December 7, 2023 Category: Environmental Health Authors: Timothy A Bargar Yongxing Jiang Source Type: research

Adult Mosquito and Butterfly Exposure to Permethrin and Relative Risk Following ULV Sprays from a Truck-Mounted Sprayer
This study compared the risk of permethrin to adult mosquitoes and adult butterflies to assess the likelihood that the butterflies would be affected following such sprays. Permethrin toxicity values were determined for Aedes aegypti and Culex quinquefasciatus (LD50s of 81.1 and 166.3 ng/g dw, respectively) and then combined with published toxicity data in a species sensitivity distribution for comparison with published permethrin toxicity data for adult butterflies. The sensitivity distributions indicated adult butterflies and mosquitoes are similarly sensitive, meaning relative risk would be a function of exposure. Exposu...
Source: Archives of Environmental Contamination and Toxicology - December 7, 2023 Category: Environmental Health Authors: Timothy A Bargar Yongxing Jiang Source Type: research

An adverse outcome pathway-based approach to assess the neurotoxicity by combined exposure to current-use pesticides
Toxicology. 2023 Nov 29:153687. doi: 10.1016/j.tox.2023.153687. Online ahead of print.ABSTRACTExposure to multiple pesticides in daily life has become an important public health concern. However, the combined effects of pesticide mixtures have not been fully elucidated by the conventional toxicological testing used for individual chemicals. Grouping of chemicals by mode of action using common key events (KEs) in the adverse outcome pathway (AOP) as endpoints could be applied for efficient risk assessment of combined exposure to multiple chemicals. The purpose of this study was to investigate whether exposure to multiple pe...
Source: Toxicology - December 1, 2023 Category: Toxicology Authors: Tetsushi Hirano Yoshinori Ikenaka Kei Nomiyama Masato Honda Nobuo Suzuki Nobuhiko Hoshi Yoshiaki Tabuchi Source Type: research

An adverse outcome pathway-based approach to assess the neurotoxicity by combined exposure to current-use pesticides
Toxicology. 2023 Nov 29:153687. doi: 10.1016/j.tox.2023.153687. Online ahead of print.ABSTRACTExposure to multiple pesticides in daily life has become an important public health concern. However, the combined effects of pesticide mixtures have not been fully elucidated by the conventional toxicological testing used for individual chemicals. Grouping of chemicals by mode of action using common key events (KEs) in the adverse outcome pathway (AOP) as endpoints could be applied for efficient risk assessment of combined exposure to multiple chemicals. The purpose of this study was to investigate whether exposure to multiple pe...
Source: Toxicology - December 1, 2023 Category: Toxicology Authors: Tetsushi Hirano Yoshinori Ikenaka Kei Nomiyama Masato Honda Nobuo Suzuki Nobuhiko Hoshi Yoshiaki Tabuchi Source Type: research