Experimental study on the protective mechanism of mesenchymal stem cells against central nervous system injury in heat stroke

CONCLUSIONS: These results suggested that MSCs injection may provide therapeutic effects in HS of rats by improving the liver and kidney function, reducing the CNS damage. Moreover, MSCs injection inhibited the brain inflammatory response of HS rats, and the BDNF-TrkB and P38/MAPK signal pathways may be involved.which may provide a potential mechanism for HS therapy by MSCs administration.PMID:35546753 | DOI:10.2174/1574888X17666220511144254

Source: Current Stem Cell Research and Therapy - May 13, 2022 Category: Stem Cells Authors: Rui Yuan Lu Wang Zi-Hui Deng Meng-Meng Yang Yan Zhao Jie Hu Yu Zhang Yun Li Meng Liu Shi-Fei Liu Fei-Hu Zhou None Hanyu-Zhu Hong-Jun Kang Source Type: research