Subacute Thyroiditis Following SARS-CoV-2 Vaccines: Six Cases Report and Review of the Literature
Horm Metab Res DOI: 10.1055/a-1804-9561Subacute thyroiditis (SAT) is an inflammatory disease of the thyroid that
develops following viral upper respiratory tract infections. SARS-CoV-2 virus,
the cause of COVID-19, binds to the Angiotensin-Converting Enzyme-2 (ACE2)
molecule expressed on the target cell surface. Thyroid gland shows high levels
of ACE2 expression. The cases of SARS-CoV-2-related subacute thyroiditis and
Graves’ disease have been reported. It has recently been noted that
vaccines for SARS-CoV-2 also induce autoimmune and inflammatory reactions. We
present six (4 male, 2 female) cases of SAT that developed after mRNA and
inactivated SARS-CoV-2 vaccines. And we have reviewed the literature. SAT was
seen in 5 patients after mRNA vaccine, in one after inactivated vaccine. Their
clinic and laboratory findings suggested to SAT. They were treated with
nonsteroid anti-inflamatory drugs and/or methylprednisolone.They
recovered within few weeks. Out patients did not have permanent hypothyroidism
after SAT. The history of SARS-CoV-2 vaccination should be questioned in
patients with subacute thyroiditis in pandemic days. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text
Source: Hormone and Metabolic Research - Category: Endocrinology Authors: Kurtulmus, Neslihan Kayikci, Kubra Tags: Original Article: Endocrine Care Source Type: research
More News: Autoimmune Disease | Covid Vaccine | COVID-19 | Endocrinology | Hormones | Hypothyroidism | Laboratory Medicine | Methylprednisolone | Pandemics | Respiratory Medicine | SARS | Thyroid | Thyroiditis | Vaccines